Background: To evaluate the performance of Siriraj liquid-based cytology (LBC) for cervical neoplasia screening after increasing use of this technology. Materials and Methods: Cytological reports of 103,057 Siriraj-LBC specimens obtained in 2007-2009 were compared with those of 23,676 specimens obtained in 2006. Results: Comparing with the year 2006, the 2007-2009 patients were slightly older ($43.4{\pm}12.yr$ vs $42.7{\pm}12.2yr$, p <0.001), and their specimens had much lower proportion of unsatisfactory slides (OR=0.06, 95%CI 0.04-0.09) with comparable detection rates (3.96% vs 3.70%, p=0.052) but different proportions of various cytological abnormalities (p<0.001). The 2007-2009 Siriraj-LBC had a negative predictive value (NPV) for cervical intraepithelial neoplasia 2+ (CIN2+) of 97.6% and an overall positive predictive value (PPV) of 43.9%. The PPV for CIN2+ varied with types of abnormal cytology, from 13.7% to 93.8% in atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LSIL), atypical squamous cells cannot exclude HSIL (ASC-H), high-grade squamous intraepithelial lesion (HSIL), atypical glandular cells (AGC), to squamous cell carcinoma (SCC), respectively. The PPVs for CIN2+ in ASCUS and LSIL were comparable, but the PPV for CIN1 was higher for LSIL than for ASCUS (41.63% vs 16.32%). Conclusions: Siriraj-LBC has demonstrated a stable detection rate and NPV for CIN2+ of >95% since the first year of use. The comparable PPVs for CIN2+ of ASCUS and LSIL suggests that these two conditions may undergo similar management; other cytological abnormalities need immediate evaluation.
The image display is an Important component of PACS and of medical digital imaging chain. Displayed image qualify is affected by the physical characteristics of display device, appropriate clinical settings and calibrations, and ambient lighting conditions. The performance of display systems is continuously degraded over time due to luminance deterioration and changes of clinical setting parameters. A routine QC is recommended because the performance of display systems is continuously degraded over time. Ten flat panel monochrome LCD display devices were included in the evaluation of the QC effect. The effect of QC on primary class LCD medical display devices for selected QC tests was evaluated by comparing the performances, luminance response, luminance dependencies, display resolution and display chromaticity in this study, of before and after the calibration procedures. The effects of the QC are significant to luminance response and luminance spatial dependencies test and the other side, are slight to the display resolution and display chromaticity test. A routine QC of display device is essential for the consistency of medical image display and presentation. The study of the QC effects of display devices will play an important role in practical QC procedures of display devices.
The Journal of the Convergence on Culture Technology
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v.9
no.4
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pp.303-308
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2023
The purpose of this study is to provide a practical guide for establishing BSC that can be practically applied by SMEs. To this end, a case study was conducted to establish a performance evaluation system through a field-required Balanced Scorecard (BSC) for company J, a tent pole manufacturer, and to provide a management strategy system map. As a survey method, the requirements of the ordering organization were organized through a comparison of the BSC-related proposal requests in the first stage. The BSC establishment method was organized through the arrangement of the second stage result report. The 3rd stage BSC derived KPI indicators for SMEs for each of the 4 perspectives. A corporate vision was derived through a 4-step SWOT analysis. A strategy map was developed through 5-step field-required KPI, weight setting, and BSC. The 6-step final strategy system was also drawn up. As a result of the study, the four perspectives of the BSC were reconstructed by department. That is, the financial (financial) perspective is from the executives' perspective, the customer's perspective is from the sales department's perspective, the internal process perspective is from the design department/production quality department's perspective, and the learning/innovation perspective is from the management department's perspective. In addition, a total of 11 CSFs and a total of 49 KPIs of J company were derived. The limitation of the study is that the final strategy system through the company's BSC has only been carried out, and it needs to be linked with the company's compensation system in the future.
The Ministry of National Defense is pushing for the Defense Acquisition Program to build strong defense capabilities, and it spends more than 10 trillion won annually on defense improvement. As the Defense Acquisition Program is directly related to the security of the nation as well as the lives and property of the people, it must be carried out very transparently and efficiently by experts. However, the excessive diversification of laws and regulations related to the Defense Acquisition Program has made it challenging for many working-level officials to carry out the Defense Acquisition Program smoothly. It is even known that many people realize that there are related regulations that they were unaware of until they push ahead with their work. In addition, the statutory statements related to the Defense Acquisition Program have the tendency to cause serious issues even if only a single expression is wrong within the sentence. Despite this, efforts to establish a sentence comparison system to correct this issue in real time have been minimal. Therefore, this paper tries to propose a "Comparison System between the Statement of Military Reports and Related Laws" implementation plan that uses the Siamese Network-based artificial neural network, a model in the field of natural language processing (NLP), to observe the similarity between sentences that are likely to appear in the Defense Acquisition Program related documents and those from related statutory provisions to determine and classify the risk of illegality and to make users aware of the consequences. Various artificial neural network models (Bi-LSTM, Self-Attention, D_Bi-LSTM) were studied using 3,442 pairs of "Original Sentence"(described in actual statutes) and "Edited Sentence"(edited sentences derived from "Original Sentence"). Among many Defense Acquisition Program related statutes, DEFENSE ACQUISITION PROGRAM ACT, ENFORCEMENT RULE OF THE DEFENSE ACQUISITION PROGRAM ACT, and ENFORCEMENT DECREE OF THE DEFENSE ACQUISITION PROGRAM ACT were selected. Furthermore, "Original Sentence" has the 83 provisions that actually appear in the Act. "Original Sentence" has the main 83 clauses most accessible to working-level officials in their work. "Edited Sentence" is comprised of 30 to 50 similar sentences that are likely to appear modified in the county report for each clause("Original Sentence"). During the creation of the edited sentences, the original sentences were modified using 12 certain rules, and these sentences were produced in proportion to the number of such rules, as it was the case for the original sentences. After conducting 1 : 1 sentence similarity performance evaluation experiments, it was possible to classify each "Edited Sentence" as legal or illegal with considerable accuracy. In addition, the "Edited Sentence" dataset used to train the neural network models contains a variety of actual statutory statements("Original Sentence"), which are characterized by the 12 rules. On the other hand, the models are not able to effectively classify other sentences, which appear in actual military reports, when only the "Original Sentence" and "Edited Sentence" dataset have been fed to them. The dataset is not ample enough for the model to recognize other incoming new sentences. Hence, the performance of the model was reassessed by writing an additional 120 new sentences that have better resemblance to those in the actual military report and still have association with the original sentences. Thereafter, we were able to check that the models' performances surpassed a certain level even when they were trained merely with "Original Sentence" and "Edited Sentence" data. If sufficient model learning is achieved through the improvement and expansion of the full set of learning data with the addition of the actual report appearance sentences, the models will be able to better classify other sentences coming from military reports as legal or illegal. Based on the experimental results, this study confirms the possibility and value of building "Real-Time Automated Comparison System Between Military Documents and Related Laws". The research conducted in this experiment can verify which specific clause, of several that appear in related law clause is most similar to the sentence that appears in the Defense Acquisition Program-related military reports. This helps determine whether the contents in the military report sentences are at the risk of illegality when they are compared with those in the law clauses.
Park, Young-Hee;Kam, Sin;Han, Chang-Hyun;Cha, Byung-Jun;Kim, Tae-Woong;Gie, Jung-Aie;Kim, Byong-Guk
Journal of agricultural medicine and community health
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v.25
no.2
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pp.353-377
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2000
This study was performed to investigate the performance state and improvement countermeasure of Primary Health care Posts(PHPs). The operation reports of PHPs(1996 330 PHPs, 1999 313 PHPs) located in Kyongsangbuk-Do and data collected by self-administered questionnaire survey of 280 community health practitioners(CHPs) were analyzed. The major results were as follows: Population per PHP in 1999 decreased in number compared with 1996. But population of the aged increased in number. The performance status of PHP in 1999 increased compared with 1996. A hundred forty one community health practitioners(50.4%) replied that the fiscal standing of PHP was good. Only 1.4% replied that the fiscal standing of PHP was difficult. For the degree of satisfaction in affairs, overall of community health practitioners felt proud. The degree of cooperation between PHP and public health institutions was high and the degree of cooperation of between PHP and private medical institutions was high. The degree of cooperation between PHP and Health Center was significantly different by age of CHP, the service period of CHP, and CHP's service period at present PHP. Over seventy percent of CHPs replied that they had cooperative relationship with operation council, village health workers, community organization. CHPs who drew up the paper on PHP's health activity plan were 96.4 % and only 11.4% of CHPs participated drawing up the report on the second community health plan. CHPs who grasped the blood pressure and smoking status of residents over 70% were 88.2%, 63.9% respectively and the grasp rate of blood pressure fur residents were significantly different according to age and educational level of CHP. CHPs received job education in addition continuous job education arid participated on research program in last 3 years were 27.5%, respectively. CHPs performed the return health program for residents in last 3years were 65.4%. Over 95% of CHPs replied that PHPs might be necessary and 53.9% of CHPs replied that the role of PHPs should be increased. CHPS indicated that major reasons of FHPs lockout were lack of understanding for PHP and administrative convenience, CHPs were officials in special government service governors intention of self-governing body. CHPs suggested number of population in health need such as the aged and patients with chronic disease, opinion of residents, population size, traffic situation and network in order as evaluation criteria for PHP and suggested results of health performance, degree of relationship with residents, results of medical examination anti treatment, ability for administration and affairs in order as evaluation criteria for CHP. CHPs replied that the important countermeasures for PHPs under standard were affairs improvement of PHPs and shifting of location to health weakness area in city. Over 50% of CHPs indicated that the most important thing for improvement of PHPs was affairs adjustment of CLIP. And CHPs suggested that health programs carried out in priority at PHP were management of diabetes mellitus and hypertention. home visiting health care, health care for the aged. The Affairs of BLIP should be adjusted to satisfy community health need and health programs such as management of diabetes mellitus and hypertention, home visiting health care, health care for the aged should be activated in order that PHPs become organization reflecting value system of primary health care.
OBJECTIVES : Bituminous materials, such as tack coat, are utilized between pavement layers for improving the bond strength in pavement construction sites. The standards regarding the application of bituminous material are not clearly presented in the Korean construction guideline without RS(C)-4. Hence, the objective of this study is to determine the optimum content of bituminous materials by analyzing interlayer shear strength (ISS) from the direct shear tester, which was developed in this research. The shear strength of tack coat was defined with the sort of bituminous materials. METHODS : The mixtures for the shear test were made using marshall mix design. The specimens were vertically and horizontally separated for the direct shear test. The separated specimens were bonded using bituminous material. The objectives of the experiment are to determine the performance of bond and shear properties resulting from slippage, rutting, shovel, and corrugation of asphalt pavements. A machine based on the Louisiana interlayer shear strength tester (LISST) of NCHRP Report-712 was developed to determine the ISS. The applied types of tack coat were RS(C)-4, AP-3, QRS-4, and BD-coat with contents of $0.3{\ell}/m^2$, $0.45{\ell}/m^2$, $0.6{\ell}/m^2$, and $0.8{\ell}/m^2$, respectively. RESULTS : Table 2 gives the results of the direct shear test using the developed shear machine. The BD-coat type indicated the highest average ISS value compared to the others. Between the surface and binder course, optimum tack coat application rates for AP-3, RS(C)-4, QRS-4, and BD-Coat were $0.6{\ell}/m^2$, $0.3{\ell}/m^2$, $0.6{\ell}/m^2$, and $0.45{\ell}/m^2$, respectively. These optimum contents were determined using the ISS value. CONCLUSIONS : The ISS values of AP-3, RS(C)-4, and QRS-4 showed similar tendencies when ISS increased in the range $0.3{\sim}0.6{\ell}/m^2$, while ISS decreased when the applied rate exceeded $0.6{\ell}/m^2$. Similarly, the highest ISS value of the BD-coat was observed when the applied rate was $0.45{\ell}/m^2$. However, shear strength was similar to the maximum value of ISS when the tack-coat application rate of BD-Coat exceeded $0.45{\ell}/m^2$.
Woo, Ye-Shin;Lee, Ye-Jin;Kim, Yeon-Ju;Kang, Jae-Won;Park, Hae Yean
Therapeutic Science for Rehabilitation
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v.6
no.2
/
pp.59-70
/
2017
Objective: It is important to assess the participation and understand the characteristics of participation for setting goal of the child's treatment and strengthening participation. In this study, we verified the validity of the LIFE-H 1.0, so that domestic occupational therapists can systematically evaluate children's participation. Methods: This study was conducted for about 2 months from February to April 2016 in 47 children with disabilities and non-disabled children. We divided the children into two groups aged 0-4 years and 5-13 years old and conducted a self-report questionnaire to parents. The collected data were verified by SPSS(Statistical Package for Social Science) statistical analysis program. Results: There was no difference between the two groups in general characteristics. In comparison of two groups, a significant difference(p<.05) was found in the LIFE-H 1.0 total performance and satisfaction score and the high discriminant validity was verified. Conclusion: The ultimate goal of occupational therapy is to increase participation. Therefore, the occupational therapist must be able to assess the level of participation and than set the goal of intervention. This study confirms the high level of validity and expects that Korean version of LIFE-H 1.0 will be widely used in clinical field and research.
Yoon, D. H.;Kim, T. H.;Lee, K. H.;Park, E. W.;Lee, H. K.;Cheong, I. C.;Hong, K. C.
Journal of Animal Science and Technology
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v.45
no.1
/
pp.13-22
/
2003
Growth Hormone (GH) gene is a member of gene family through the evolutionary process from a small common ancestral gene by a series of gene duplications. The role of the GH in growth and performance controls has been extensively studied in human, mice and livestock. Many researchers have considered GH as a strong candidate gene for evaluation of genetic polymorphisms that could be associated with economic traits in cattle. We report here a novel missense mutation within the exon 5 of the bovine Growth Hormone (bGH) gene. We could amplified 522 bp fragments from eight unrelated Hanwoo cattle by PCR, then, subsequently cloned and sequenced. An Msp I RFLP corresponding to a C to T transition was observed at position 2258 nt. From this result, we could predict a missense mutation (Arg to Trp) at codon 166 in a highly conserved region among many mammals. Codominant Mendelian segregation of the two alleles, Msp I (+) and Msp I (-), was observed in two full-sib F2 families (n = 32, African taurine Bos taurus ${\times}$ African zebu Bos indicus) and eight half-sib Hanwoo families. For the availability of genetic marker, we have performed PCR-RFLP with a large number of individual animals from 15 different cattle breeds (European and Asian taurines, and African indicines). Consideration of breed frequencies of Msp I (-) allele in relation to breed type and their geographic origins, shows higher frequencies in humped breeds or Asian cattle breeds than in humpless or European breeds. This result indicates that the missense mutation can be contributed the functional significance such as the signal transduction through the receptor binding, also may be used as a marker for selection of the economic traits in Hanwoo.
Lee, Jun Ho;Shin, Sunmy;Park, Gyu Nam;Rhee, Hyug-Gyo;Yang, Ho-Soon
Current Optics and Photonics
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v.1
no.2
/
pp.107-112
/
2017
An adaptive optics system can be simulated or analyzed to predict its closed-loop performance. However, this type of prediction based on various assumptions can occasionally produce outcomes which are far from actual experience. Thus, every adaptive optics system is desired to be tested in a closed loop on an optical test bench before its application to a telescope. In the close-loop test bench, we need an atmospheric simulator that simulates atmospheric disturbances, mostly in phase, in terms of spatial and temporal behavior. We report the development of an atmospheric turbulence simulator consisting of two point sources, a commercially available deformable mirror with a $12{\times}12$ actuator array, and two random phase plates. The simulator generates an atmospherically distorted single or binary star with varying stellar magnitudes and angular separations. We conduct a simulation of a binary star by optically combining two point sources mounted on independent precision stages. The light intensity of each source (an LED with a pin hole) is adjustable to the corresponding stellar magnitude, while its angular separation is precisely adjusted by moving the corresponding stage. First, the atmospheric phase disturbance at a single instance, i.e., a phase screen, is generated via a computer simulation based on the thin-layer Kolmogorov atmospheric model and its temporal evolution is predicted based on the frozen flow hypothesis. The deformable mirror is then continuously best-fitted to the time-sequenced phase screens based on the least square method. Similarly, we also implement another simulation by rotating two random phase plates which were manufactured to have atmospheric-disturbance-like residual aberrations. This later method is limited in its ability to simulate atmospheric disturbances, but it is easy and inexpensive to implement. With these two methods, individually or in unison, we can simulate typical atmospheric disturbances observed at the Bohyun Observatory in South Korea, which corresponds to an area from 7 to 15 cm with regard to the Fried parameter at a telescope pupil plane of 500 nm.
Lee, Soo Yeon;Lee, Jun Ho;Kim, Young-Gwang;Rhee, Hyug-Gyo;Lee, Munseob
Korean Journal of Optics and Photonics
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v.33
no.6
/
pp.267-274
/
2022
In this paper, we report the design and fabrication of binary diffractive optical elements (DOEs) for random-dot-pattern projection for Schlieren imaging. We selected the binary phase level and a pitch of 10 ㎛ for the DOE, based on cost effectiveness and ease of manufacture. We designed the binary DOE using an iterative Fourier-transform algorithm with binary phase optimization. During initial optimization, we applied a computer-generated pseudorandom dot pattern of uniform intensity as a target pattern, and found significant intensity nonuniformity across the field. Based on the evaluation of the initial optimization, we weighted the target random dot pattern with Gaussian profiles to improve the intensity uniformity, resulting in the improvement of uniformity from 52.7% to 90.8%. We verified the design performance by fabricating the designed binary DOE and a beam projector, to which the same was applied. The verification confirmed that the projector produced over 10,000 random dot patterns over 430 mm × 430 mm at a distance of 5 meters, as designed, but had a slightly less uniformity of 84.5%. The fabrication errors of the DOE, mainly edge blurring and spacing errors, were strong possibilities for the difference.
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