• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11b
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• pp.416-421
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• 2002

This paper dealt with an experimental study on the hydro-elastic vibration of clamped perforated rectangular plates submerged in water. The penetration of holes in the plates had a triangular pattern with P/D (pitch to diameter) 1.750, 2.125, 2.500, 3.000 and 3.750. The natural frequencies of the perforated plates in air were obtained by the analytical method based n the relation between the reference kinetic and maximum potential energy and compared with the experimental results. Good agreement between the results was found for the natural frequencies of the perforated plates in air. It was empirically found that the natural frequencies of the perforated plate in air increase with an increase of P/D, on the other hand, the natural frequencies of the perforated plate in contact with water decrease with an increase of P/D. Additionally, the effect of the submerged depth on the natural frequency was investigated.

• Journal of Pharmaceutical Investigation
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• v.41 no.6
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• pp.347-354
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• 2011

Repeated oral administration of loxoprofen can induce many side effects such as gastric disturbances and acidosis. Therefore, we considered alternative routes of administration for loxoprofen to avoid such adverse effects. The aim of this study was to develop an ethylene-vinyl acetate (EVA) matrix system containing a permeation enhancer for enhanced transdermal delivery of loxoprofen. The EVA matrix containing loxoprofen was fabricated and the effects of drug concentration, temperature, enhancer and plasticizer on drug release were studied from the loxoprofen-EVA matrix. The solubility of loxoprofen was highest at 40% (v/v) PEG 400. The release rate of drug from drug-EVA matrix increased with increased loading dose and temperature. The release rate was proportional to the square root of loading dose. The activation energy (Ea), which was measured from the slope of log P versus 1000/T, was 5.67 kcal/mol for a 2.0% loaded drug dose from the EVA matrix. Among the plasticizer used, diethyl phthalate showed the highest release rate of loxoprofen. Among the enhancers used, polyoxyethylene 2-oleyl ether showed the greatest enhancing effect. In conclusion, for the enhanced controlled transdermal delivery of loxoprofen, the application of the EVA matrix containing plasticizer and penetration enhancer could be useful in the development of a controlled drug delivery system.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.11
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• pp.1455-1462
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• 2018

As the interests in eco-friendly energy has increased, the interests in Electric Vehicles(EVs) are increasing as well. Moreover, due to the government's economic support for EVs, penetration level of it has rapidly increased. These sharp increases, however, induce various problems in distribution system, such as voltage/frequency variations, peak demand increasement, demand control, etc. To minimize these possible matters, lots of research have conducted. Nevertheless, most of it assumed extremely important factors, such as numbers and charging patterns of EVs. It inevitably results in errors in their research, and thus make it difficult to prevent the possible matters from EVs. In this paper, therefore, we use actual EVs charging data from KEPCO, and analysis and deduction of it were conducted. The simulations were carried out for four aspect(season, region, purpose).

• Journal of Pharmaceutical Investigation
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• v.39 no.6
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• pp.437-443
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• 2009

To develop a topical bioadhesive formulation of clotrimazole for enhanced transdermal delivery, hydroxypropyl methylcellulose gel containing permeation enhancer was formulated and permeation studies were carried out. The release characteristics of the drug from the gel formulation were examined according to the receptor medium, drug concentration, and temperature. The rate of drug release from the gel increased with increasing drug concentration and temperature. The activation energy (Ea) of drug permeation, which was calculated from the slope of log P versus 1/T plots, was 14.41kcal/mol for a 1%(w/w) loading dose. The enhancer, such as saturated, unsaturated fatty acids, pyrrolidones, propylene glycol derivatives, glycerides, and non-ionic surfactants, were incorporated onto the gels to increase the amount of drug permeation into the skin. Among the enhancers used, polyoxyethylene 2-oleyl ether showed the highest level of enhancement. These results show that clotrimazole gels containing polyoxyethylene 2-oleyl ether could be used for the enhanced transdermal delivery of clotrimazole.

• Journal of the Korean Applied Science and Technology
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• v.22 no.2
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• pp.182-190
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• 2005

The propagation of light radiation within tissues is an important problem that confronts the dosimetry of therapeutic laser delivery and the development of diagnostic spectroscopy. In the clinical application of photodynamic therapy(PDT) and in photobiology, the photon deposition within a tissue determines the spatial distribution of photochemical reactions. Scattered light is measured as a function of the distance (r) between the axis of the incident beam and the detection spot. Consequently, knowledge of the photosensitizer(Chlorophyll-a) function that characterizes a phantom is important. To obtain the results of scattering coefficients(${\mu}s$) of a turbid material from diffusion described by experimental approach. It was measured the energy fluency of photon radiation at the position of penetration depth. From fluorescence experimental method obtained the analytical expression for the scattered light as the values of $(I\;/I_o)_{wavelength}$ vs the distance between the center of the incident beam and optical fiber in terms of the condition of "in situ spectroscopy(optically thick)" and real time by fluorometric measurements.

• Proceedings of the KWS Conference
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• 2006.10a
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• pp.253-255
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• 2006

Grey relational analysis has been carried out to develop a new approach for optimization of Nd:YAG laser and MIG hybrid welding parameters. The quality of welded material depends on welding parameters. The parameters chosen for current study include wire type, shielding gas, laser energy, laser focus, traveling speed, and wire feed rate. The welding experiments were performed on 6K21-T4 aluminum alloy sheet. Functional demands on products may vary widely depending on their use. The ultimate tensile stress, width, and penetration were chosen as the optimization criterion. Practice based on an orthogonal array which is following Taguchi's method has been progressed. Base on the results of grey relational analysis, the optimal process parameters were obtained. This integrated work was judged and it is observed that the results obtained by using the optimal parameters are much improved compared to those obtained through initial setting.

• KIEAE Journal
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• v.7 no.4
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• pp.57-62
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• 2007

At the moment, the reduction of building energy consumption is a unavoidable task of mankind for conserving global environment. Decreasing overall U-value of building envelope and air infiltration, especially in Korean climate condition with clear four seasons, are the obvious solutions for the objective. Thus low glazing ratio with small window openings are required for heating and cooling load reduction in buildings. Using larger window openings could provide better natural ventilation but it also increases the direct solar radiation penetration into indoor space, heat gain in summer and heat loss in winter. On the other hand, the ventilation rates decreasing problem with smaller window openings could be occurred. As a solution for it, the use of casement window can cause increasing natural ventilation rates by wing wall effect. This paper focuses on deduce the most efficient opening type of casement window in Korean climate. To estimate ventilation performance of each opening types, CFD simulation was used. The best performance of opening type in every wind direction is opening both windows to the center and the most appropriate opening type for Korean climate is also opening both windows to center.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.4
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• pp.533-538
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• 2016

In a power grid that has a high penetration of wind power, the highly-fluctuating output power of wind turbine generators (WTGs) adversely impacts the power quality in terms of the system frequency. This paper proposes a power smoothing scheme of a variable-speed WTG that can smooth its fluctuating output power caused by varying wind speeds, thereby improving system frequency regulation. To achieve this, an additional loop relying on the frequency deviation that operates in association with the maximum power point tracking control loop, is proposed; its control gain is modified with the rotor speed. For a low rotor speed, to ensure the stable operation of a WTG, the gain is set to be proportional to the square of the rotor speed. For a high rotor speed, to improve the power smoothing capability, the control gain is set to be proportional to the cube of the rotor speed. The performance of the proposed scheme is investigated under varying wind speeds for the IEEE 14-bus system using an EMTP-RV simulator. The simulation results indicate that the proposed scheme can mitigate the output power fluctuation of WTGs caused by varying wind speeds by adjusting the control gain depending on the rotor speed, thereby supporting system frequency regulation.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.3
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• pp.440-449
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• 2003

Residual strength of fiber metal laminates after impact was studied. 3/4 lay up FML was fabricated using 4 ply prepreg, 2 ply aluminum sheets, and 1 ply steel sheet. Quasi isotropic ([0/45/90/-45]s) and orthotropic ([0/90/0/90]s) FRP were also fabricated to compare with FML. Impact test were conducted by using instrumented drop weight impact machine (Dynatup, Model 8250). Penetration load and absorbed energy of FML were superior to those of FRPs. Tensile tests were conducted to evaluate the residual strength after impact. Strength degradation of FML was less than that of FRP. This means that the damage tolerance of FML is excellent than that of FRP. Residual strength of each specimen was predicted by using Whitney and Nuismer(WN) Model. Impact damage area is assumed as a circular notch in WN model. Damage width is defined as the average of back face and top face damage width of each specimen. Average stress and point stress criterions were used to calculate the characteristic length. It is supposing that a characteristic length is a constant. The distribution of characteristic length shows that the assumption is reasonable. Prediction was well matched with experiment under both stress criterions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.33 no.12
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• pp.992-999
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• 2009

The focus of this study is placed on the behavior characteristics of gasoline spray under condition field of room temperature and pressure. To analyze the behavior and flow characteristics of injected fuel spray is important in speculation of mixture formation process. Also the exhausted emissions from actual engines can be controlled by the analyzed results. The ${\varphi}$(degree of freedom) and K(energy ratio of particle motion) are selected as the simulation parameter. The factors affect characteristics of spray structure, and the factors are included in the sub-program of the KIVA-II code. In this study, the simulation study by modified KIVA-II code was conducted and the calculated results obtained by the modified KIVA-II code show good agreements with experimental results. As a result, applying the improved TAB model with ${\varphi}$=8 and K=2 to simulation analysis of the KIVA-II code is sufficiently useful for analyzing the macro characteristics in spray structure, such as the spray tip penetration of injected fuel spray.