• Clinical and Experimental Reproductive Medicine
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• 제11권1호
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• pp.33-37
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• 1984

A nornal pregnancy with IUD in situ, which is extremely rare case, is reported with the brief reviews of literatures. And assoc i at i on between intrauterine device and pelvic inflammatory disease is also rported.

• 대한한방부인과학회지
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• 제34권4호
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• pp.46-61
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• 2021

Objectives: The purpose of this review is to overview the studies of traditional herbal medicine for chronic pelvic inflammatory disease. Methods: We searched relevant studies using seven databases (The Journal of Korean obstetrics & gynecology, National Digital Science Library (NDSL), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Pubmed, Cochrane, Chinese National Knowledge Infrastructure (CNKI)). Data retrieval was carried out on April 5, 2021 and the papers published from January 1, 2015 to March 31, 2021 were included. The risk of bias was assessed by using Cochrane's risk of bias tool. Results: 524 studies were searched in domestic and foreign databases, and 7 studies were finally selected. In all studies, the treatment group was treated with oral traditional herbal medicine and the control group was treated with western medicine. Although the evaluation index was slightly different for each study, all studies used total efficacy rate index. In all 7 studies, the treatment group was more effective than the control group. Conclusions: Traditional herbal medicine can be an effective option in treating chronic pelvic inflammatory disease. Further high quality studies which include large number should be carried out to confirm the evidence and safety of traditional herbal medicine treatment.

• Korean Journal of Radiology
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• 제2권2호
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• pp.97-104
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• 2001

Pelvic fistulas may result from obstetric complications, inflammatory bowel disease, pelvic malignancy, pelvic radiation therapy, pelvic surgery, or other traumatic causes, and their symptoms may be distressing. In our experience, various types of pelvic fistulas are identified after pelvic disease or pelvic surgery. Because of its close proximity, the majority of such fistulas occur in the pelvic cavity and include the vesicovaginal, vesicouterine, vesicoenteric, ureterovaginal, ureteroenteric and enterovaginal type. The purpose of this article is to illustrate the spectrum of imaging features of pelvic fistulas.

• 대한한방부인과학회지
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• 제27권3호
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• pp.158-167
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• 2014

Objectives: This study aims to report the effect of Korean medicine treatments on a pelvic inflammatory disease (PID). Methods: The patient was treated with Qingbaozhuyu-tang, acupuncture at Jungwan (CV12), Gihae (CV6), Taechung (LR3), Hapgok (LI4), Sameumgyo (SP6), Sangryo (BL3), Charyou (BL32), Jungryo (BL33), Haryo (BL34), Cheonchu (ST25), Pungryung (ST40), Duyu (ST8), Taeyang (EX-HN5). And we evaluated treatment effects by visual analogue scale (VAS) and Urine analysis (UA) Finding. Results: After treatments, the symptoms such as lower abdominal pain, pelvic pain and fever were improved and there were no abnormal findings in urine analysis. Conclusions: This study suggests that Korean medicine treatments show effective on PID treatment.

• 대한한방부인과학회지
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• 제21권1호
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• pp.99-116
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• 2008

Purpose: This study was performed to evaluate anti-inflammatory effects of Hyulbuchukeotanggamibang water extract (HBCT). Methods: In the study of anti-inflammatory effects, HBCT was investigated using cultured cells and a murine models. As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were determined in mouse lung fibroblast cells (mLFCs) and RAW264.7 cells. Results: Prior to the experiment, we investigated the cytotoxicity of HBCT. HBCT showed a safety in cytotoxicity on mLFCs. In experiment of anti-inflammatory effect, HBCT effected scavenging activity on DPPH free radical, superoxide dismutase and superoxide anion radical. HBCT inhibited $IL-1{\beta}$, IL-6, $TNF-{\alpha}$, COX-2 and NOS-II mRNA expression in a concentration-dependent manner in RAW264.7 cell line, and inhibited significantly $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ production at $100{\mu}g/\;ml$ in a concentration-dependent manner. Conclusion: These results suggest that HBCT can be used for treating diverse female diseases caused by inflammation such as endometriosis, pelvic pain, cervicitis, pelvic inflammatory disease and pelvic tuberculosis and so forth.

• 대한한방부인과학회지
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• 제22권3호
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• pp.83-98
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• 2009

Purpose: This study was performed to evaluate the anti-inflammatory effect of Eungapbang extract (EGB). Methods: To evaluate the anti-inflammatory effects of EGB, we nourished RAW 264.7 cell lines in the laboratory dish. Next, inflammatory cytokine concentrations were analyzed. Then, sera were prepared from blood after lipopolysaccharide (LPS) injection in chemically induced mouse models of intestinal inflammation, and Interleukin-1${\beta}$ (IL-1${\beta}$), interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-${\alpha}$) were measured using ELISA kits. Results: 1. EGB significantly suppressed the expression levels of IL-1${\beta}$ and NOS-II genes at 100, 50 and 10 ${\mu}g/m{\ell}$ concentrations, and IL-6, TNF-${\alpha}$ and COX-2 mRNAs at 100 and 50 ${\mu}g/m{\ell}$ concentrations. 2. EGB significantly reduced the production level of IL-1${\beta}$ and TNF-${\alpha}$ at 100${\mu}g/m{\ell}$ concentrations, and IL-6 at 100 and 50 ${\mu}g/m{\ell}$ concentrations. 3. EGB significantly decreased the production level of IL-1${\beta}$ and IL-6 in sera of acute inflammation induced mice. 4. EGB could suppress the expression level of IL-1${\beta}$ and IL-6 mRNA in spleen tissues in acute inflammation induced mice. Conclusion: On the basis of the above results, it is confirmed that the anti-inflammatory effects of EGB were recognized. Therefore, EGB is recommended as promising therapy for treatment of such ailments as pelvic inflammatory disease.

• Journal of Yeungnam Medical Science
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• 제35권1호
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• pp.127-129
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• 2018

Fitz-Hugh-Curtis syndrome (FHCS) is characterized by inflammation of the perihepatic capsules associated with the pelvic inflammatory disease (PID). FHCS is not a serious disease, but if not treated properly, it can result in increased medical costs, prolonged treatment, and dissatisfaction with treatment. However, early recognition of FHCS in the emergency department can be difficult because its symptoms or physical findings may mimic many other diseases. Although contrast-enhanced computed tomography (CECT) is the useful imaging modality for recognition of FHCS, it is available only when a high suspicion is established. We performed point-of-care ultrasonography in an 18-year-old woman who had a sharp right upper quadrant (RUQ) abdominal pain without PID symptoms and found a thickened or three-layer hepatic capsule. These findings coincided with areas showing increased hepatic capsular enhancement in the arterial phase of CECT. These results show that if the thickened or three-layer hepatic capsule without evidence of a common cause of RUQ pain is observed on ultrasonography in women of childbearing age with RUQ abdominal pain, the physician can consider the possibility of FHCS.

• 대한한방부인과학회지
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• 제19권3호
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• pp.151-173
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• 2006

Purpose : This study was performed to evaluate anti-thrombotic and anti-inflammatory effects of BokbangHongdeungPaejangSan water extract (BHPS). Methods : BHPS was investigated using cultured cells and a murine models. As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were determined in mouse lung fibroblast cells (mLFC) and RAW 264.7 cells. Results : In experiment of anti-thrombotic effect, BHPS inhibited the platelet aggregation induced by ADP and epinephrine, and inhibited pulmonary embolism induced by collagen and epinephrine. BHPS increased Platelet number and fibrinogen amount, and shortened PT and APTT in thrombus model induced by dextran. In experiment of anti-inflammatory effect, BHPS inhibited IL-1${\beta}$, IL-6, TNF-${\alpha}$, COX-2 and NOS-II mRNA expression in a concentration-dependent manner in RAW 264.7 cell line, and inhibited significantly NO production at 50, 100 ${\mu}g/ml$, and also inhibited ROS production in a concentration-dependent manner. BHPS inhibited IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production significantly in serum of acute inflammation-induced Balb/c mice, and decreased IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production in spleen tissue, but increased IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production in liver tissue. BHPS increased survival rate at the 3th day in ICR mice with lethal endotoxemia induced by LPS. Conclusion : These results suggest that BHPS can be used for treating diverse female diseases caused by thrombosis and inflammation such as endometriosis, pelvic pain, cervicitis, pelvic inflammatory disease and pelvic tuberculosis and so forth.

• 대한방사선기술학회지:방사선기술과학
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• 제28권4호
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• pp.279-286
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• 2005

목 적 : 소장조영술과 복부골반 CT검사의 진단 결과를 비교함으로써 방사선학적 영상의 특징 파악 및 질환에 따른 적절한 방사선학적 검사법을 선택하는데 기초자료를 제공하고자 한다. 대상 및 방법 : 1999년부터 2000년까지 소장조영술과 복부골반 CT검사를 병행하여 시행한 환자 284명을 대상으로 하여, 각각의 진단 소견을 병명별로 분류하였다. 소장조영술은 250 ml 황산바륨 현탁액(W/V 40W/V%, Methylcellulose+$BaSo_4$)을 경구로 복용시키고, Rt. recumbent position을 취하게 한 후 약 10분 후에 Carboxymethylcellulose solution(0.5%) 600 ml 복용시켰다. 20분, 40분, 1시간 정규촬영을 하고, 조영제가 회맹판(I-C valve)을 통과하면 투시 하에 저격촬영을 시행하였다. 복부골반전산화단층촬영은 검사 1시간 전에 $BaSO_4$+Methylcellulose 1.5 W/V% 450 ml를 복용시키고 검사직전 450 ml 추가로 복용시켰다. 요오드 성분의 비이온성 조영제 2.5 ml flow/sec로 주입하고, 조영제 주입 후 72초 지연 촬영을 하였다. 촬영은 간 상연에서부터 치골결합 부위까지 continuous scan을 시행하였으며, 검사 protocol은 Helical thick 5 mm, picth 1.375 : 1, speed 27.50, increment 5 mm, 120 kV, 245 mA로 하였다. 결 과 : 소장조영술에서는 정상(Normal)이 131예(46.1%), 감염성 장질환(Inflammatory bowel disease ; 이하 IBS)이 65예(22.9%), ischemia+ileocolitis+vasculitis 22예(7.7%), obstruction+stricture 21예(7.4%)의 순으로 나타났고, 복부골반 CT검사에서는 정상이 103예(36.3%) IBS가 65예(22.9%), wall thickening+lymphadenopathy가 42예(14.8%), fluid collection이 17예(6%)의 순으로 나타났다. 소장조영술과 복부골반 CT검사에서 동일하지 않은 결과로 진단된 경우는 소장조영술에서 정상으로 진단된 132명(46.1%) 중 14예(10.6%), 복부골반 CT검사 결과에서는 wall thickening+lymphadenopathy와 IBS로 진단되어 차이를 보였으며, 복부골반 CT검사 결과 정상으로 진단된 103예(36.3%) 중 5예(5.8%)가 소장조영술에서 ischemia+ileocolitis+vasculitis로 진단되었다. 정상으로 진단 된 235예 중 37예(15.9%)가 서로 다른 결과로 진단되어 통계적으로 유의한 차이를 보였다(P<0.05). 결 론 : 본 연구에서 특정질환에 특정검사의 진단결과가 우수하게 나타나는 것으로 조사되었으므로 방사선학적 검사의 진단적 민감도를 높이기 위해서는 처방 및 검사에 있어서 질환에 따른 적절한 검사법의 선택이 무엇보다도 중요하리라 사료된다.

• 대한세포병리학회지
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• 제2권2호
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• pp.172-178
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• 1991

Actinomycosis involving the female genital tract has increased since the advent of the intra-uterine contraceptive devices (IUD) : the incidence of actinomyces in IUD users with pelvic inflammatory disease (PID) was reported to be between 17% and 30%. However a definte relationship between actinomyces and PID has not been demonstrated as yet. We present a case of pelvic actinomycotic infection that was initially diagnosed by means of fine needle aspiration. A 57-year-old female presented with urinary frequency and difficulty for 100 days. Computerized tomographic findings showed a mixed heterogenous soft tissue mass in the left superior aspect of urinary bladder. Fine needle aspiration was done under the impression of urinary bladder cancer. Microscopically, smears disclosed many sulfur granules in necrotic background with many neutrophils, histiocytes, multinucleated giant cells and granulation tissue. These findings were confirmed by surgical removal of the mass.