• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.4
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• pp.937-945
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• 1996

Nitrous oxide has acquired widespread use as a tool for management of anxious and comprehensive pediatric dental patients. Clinical impressions have suggested that inhalation sedation with $N_2O/O_2$ reinforces the effect of other sedatives. Fifteen uncooperative children, mean age of 37months, who were regarded as fail in the first treatment using chloral hydrate-hydroxyzine orally, midazolam orally or intranasally, were sedated with the same sedatives in conjunction with $N_2O/O_2$. All the children were restrained in a pediwrap and were monitored with pulse oximeter for their heart rate and oxygen saturation. Degree of sleep, crying and movement were evaluated. The clinical results indicated that a satisfactory level of sedation was achieved in approximately two thirds of the cases (about 66 %) under those sedation manner. Complications were rare and those of treatments were successfully completed without difficulty.

• Journal of the korean academy of Pediatric Dentistry
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• v.23 no.4
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• pp.887-892
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• 1996

For the purpose of assessing the utility and cautionary aspects of pulse oximetry of which use is rapidly increased, it was applied to the maladaptive child patients with sedative drugs and evaluated the results. When pulse oximeter was used alone for vital sign monitoring, it was thought impossible to exclude the false alarm or false silence by various causes. To minimize or remove these misunderstanding, operators should have a extensive knowledge not only on the factors affecting the operation of this apparatus but also on the potential of misoperation. To review the present status of increasing risk of hypoxia during the sedation, it was thought unreasonable to solely depend upon this apparatus for vital sign monitoring. By combining with more accurate and auxiliary monitoring devices, pulse oximetry will be of greater value and can meet the clinical needs and conveniences.

• The Journal of Pediatrics of Korean Medicine
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• v.25 no.2
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• pp.8-14
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• 2011

Objectives: This study is performed to investigate the use of oriental medicine on pediatric outpatients with atopic dermatitis(AD). Methods: The study was carried out with 267 AD outpatients who visited the Department of Pediatrics, Oriental Medical Hospital from January 2010 to May 2011 and was completed by reviewing patients' chart. Results: The relative frequency of AD on the oriental pediatrics hospital was 6.8%. In a sexual distribution, the male children were more frequent than the females. In an age distribution, atopic dermatitis children visited the hospital were the most frequent in the age from 3 to 10. The highest frequency that started the oriental therapy after the outbreak of AD was from 1 month to 1 year. Approximately, 49.4% of the children who visited hospital relied on western medicine in treating their atopic dermatitis. The therapeutic effect of the oriental medicine was found to be excellent in 47.9%, no change was seen in 16.9%, and aggravation was seen in 3.4% of the patients. Less than a month of oriental treatment was the most common. The improvement depending on the length of the treatment was found to be 91.8% in more than 3 months, and 21.8% in less than 1 month. The use of the herbal medicine and herbal external treatment was seen in 67.4% and the therapeutic effect was improved in 63.3% of the patients. Conclusions: Considering the results, we can improve accommodation of oriental therapies for the pediatric outpatients with atopic dermatitis, and enhance the doctor-patient relationship to help the children with atopic dermatitis.

• Clinical and Experimental Pediatrics
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• v.64 no.12
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• pp.602-607
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• 2021

In April 2020, the Ministry of Food and Drug Safety licensed a hexavalent combined diphtheria and tetanus toxoids and acellular pertussis (DTaP), inactivated poliovirus (IPV), Haemophilus influenzae type b (Hib) conjugated to tetanus protein, and hepatitis B (HepB) (recombinant DNA) vaccine, DTaP-IPV-Hib-HepB (Hexaxim, Sanofi Pasteur), for use as a 3-dose primary series in infants aged 2, 4, and 6 months. The DTaP-IPV-Hib-HepB vaccine is highly immunogenic and safe and provides a long-term immune response based on studies performed in a variety of settings in many countries, including Korea. This report summarizes the Committee on Infectious Diseases of the Korean Pediatric Society guidelines for the use of this newly introduced hexavalent combination vaccine.

• Clinical and Experimental Pediatrics
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• v.56 no.5
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• pp.196-201
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• 2013

Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability. However, fluoroquinolone use in children is limited because juvenile animals developed arthropathy in previous experiments on fluoroquinolone use. Indications for fluoroquinolone use in patients younger than 18 years, as stated by the U.S. Food and Drug Administration, include treatment of complicated urinary tract infections and postexposure treatment for inhalation anthrax. In Korea, the systemic use of fluoroquinolones has not been approved in children younger than 18 years. Although concerns remain regarding the adverse musculoskeletal effects of fluoroquinolones in children, their use in the pediatric population has increased in many circumstances. While pediatricians should be aware of the indications and adverse effects of fluoroquinolones, recent studies have shown that the risk for musculoskeletal complications in children did not significantly increase following fluoroquinolone treatment. In addition, fluoroquinolones may be particularly helpful in treating multidrug-resistant infections that have not responded to standard antibiotic therapy in immunocompromised patients. In the present article, we provide an updated review on the safety and current recommendations for using fluoroquinolones in children.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.26 no.3
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• pp.135-145
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• 2023

Antibiotics are frequently administered during pregnancy. Although necessary to address acute infections, their use facilitates antibiotic resistance. Other associations have also been found with the use of antibiotics, such as perturbations of gut bacteria, delays in microbial maturation, and increased risks of allergic and inflammatory diseases. Little is known about how the prenatal and perinatal administration of antibiotics to mothers affects the clinical outcomes of their offspring. A literature search was conducted of the Cochrane, Embase, and PubMed engines. The retrieved articles were reviewed by two authors and verified for relevance. The primary outcome was the effect of pre- and perinatal maternal antibiotic use on clinical outcomes. Thirty-one relevant studies were included in the meta-analysis. Various aspects are discussed, including infections, allergies, obesity, and psychosocial factors. In animal studies, antibiotic intake during pregnancy has been suggested to cause long-term alterations in immune regulation. In humans, associations have been found between antibiotic intake during pregnancy and different types of infections and an increased risk of pediatric infection-related hospitalization. A dose-dependent positive association between pre- and perinatal antibiotic use and asthma severity has been reported in animal and human studies, while positive associations with atopic dermatitis and eczema were reported by human studies. Multiple associations were identified between antibiotic intake and psychological problems in animal studies; however, relevant data from human studies are limited. However, one study reported a positive association with autism spectrum disorders. Multiple animal and human studies reported a positive association between pre- and perinatal antibiotic use by mothers and diseases in their offspring. Our findings have potentially significant clinical relevance, particularly considering the implications for health during infancy and later in life as well as the related economic burden.

• Advances in pediatric surgery
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• v.13 no.1
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• pp.52-60
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• 2007

Pediatric laparoscopic appendectomy is controversial particularly in complicated appendicitis. We evaluated the outcomes of laparoscopic appendectomy (LA) and open appendectomy (OA) in simple appendicitis and complicated appendicitis respectively. Since June 2004, initial LA has been our policy in all appendicitis including complicated ones. A total of 160 patients were included in this study, consisting of 80 OA (August 2001 - August 2003) and 80 LA (June 2004 - June 2006). We compared the operating time, the length of hospital stay, the length of antibiotics use, and the postoperative complications between LA and OA. In simple appendicitis (73), there were no differences between LA and OA. However in the 87 patients with complicated appendicitis, the operating time was longer in LA (64.8 min vs. 50.2 min) but the length of hospital stay was shorter in LA than OA (8.5 days vs. 9.6 days). There was one complication in simple appendicitis group and six in complicated appendicitis group (3 cases in LA, 3 cases in OA). There was no difference in the results of LA versus OA in simple appendicitis. Therefore for simple appendicitis, LA is recommended in consideration of the cosmetic effect (fewer scar). In complicated appendicitis, early discharge was an advantage and there were no differences in complications in LA despite a longer operative time. So we conclude LA can be considered as the first choice of treatment for all pediatric appendicitis including complicated appendicitis. To confirm our impressions, more well controlled randomized prospective studied need to be done.

• Journal of the korean academy of Pediatric Dentistry
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• v.35 no.3
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• pp.523-531
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• 2008

Maxillary molar distalization is a treatment approach for patients with Class II malocclusions who do not require extractions and mesial movements of mandibular molars. The pendulum appliance is effective for distalization of the maxillary molars and independent of patient cooperation. This appliance can stabilize the maxillary premolars and use the palatal rugae area as an additional anchorage. However, caution is needed to control collateral effects, including increase of lower facial height, incisor protrusion and damage to the rugae area. This article reports the cases in which maxillary molar distalization achieved by pendulum appliance resolves the space problems and corrects the molar relationships.

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.3
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• pp.493-498
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• 1998

Computed tomography(CT) has become more widely available in recent years and is recognized as an important diagnostic tool for complex disease and condition of the orofacial structure in adults. In pediatric patients, especially in the mixed dentition period, the number of superimposing dental structures in the jaw bone is much greater than in the permanant dentition period. Therefore, in spite of radiation risk, computed tomography should sometimes be used in pediatric patients in order to obtain a precise and valid diagnosis. This case study presents clinical application of computed tomography on patients visiting department of pediatric dentistry in Seoul National University Dental Hospital. The results obtained through these cases were summarized as follow : 1. Localization of impacted teeth using CT allows for efficient treatment planning leading to reduced postoperative complications. 2. In orthodontic traction of impacted permanent teeth, utilization of CT made exact localization of window site and determination of prognosis possible. 3. Use of CT made possible definite diagnosis of lesions in the jaw that were only suspected on plain film radiographs. 4. Careful selection is necessary when applying CT on children due to increased radiation dose and high cost.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.4
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• pp.630-635
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• 2004

The etiology of mesiodens is unknown but the most widely accepted theory is the hyperactivity of the dental lamina. Complications of mesiodens are delayed or prevented eruption of maxillary central incisors, displacement or rotation of permanent teeth, crowding of affected region, abnormal diastema or permanent space closure, dilaceration or abnormal root development of permanent teeth, primordial or follicular cyst formation, root resorption of adjacent teeth, eruption into nasal cavity. If mesiodens rotate the maxillary central incisors, space deficiency is not common and relapse is very common. So overcorrection is needed. To prevent the rotational relapse, early treatment, overcorrection, long retention period, properly formed proximal surface, use of coupled force, and surgical techniques have been suggested. The authors present two cases, whose chief complain were severely rotated maxillary incisors by mesiodens, treated by orthodontic and surgical technique and showed good results.