• Korean Journal of Food Science and Technology
• /
• v.33 no.2
• /
• pp.209-215
• /
• 2001

This study was conducted to examine the effects of 2,2,6,6-tetramethyl-1-piperidine oxoammonium ion(TEMPO) and sodium bromide(NaBr) for the selective oxidation on primary alcohol groups of rice starch molecules in rice flour and to use oxidized rice flour in Julpyun to extend its shelf life. Reaction time decreased with higher levels of TEMPO and NaBr. Yield and selectivity decreased with increased NaBr levels. TEMPO increased yield until certain levels, but decreased thereafter. The levels of TEMPO and NaBr for the preparation of oxidized rice flour were determined as 0.9 and 44 mM/100 mM anhydroglucose unit, respectively. Water and oil binding capacities, and viscosity increased significantly by the oxidation of rice flour. The partial replacement of rice flour with oxidized rice flour increased peak viscosity and decreased setback. Oxidized rice flour with the increased amount of water showed positive effect on the textural properties of Julpyun during storage.

• Journal of Ginseng Research
• /
• v.39 no.2
• /
• pp.169-177
• /
• 2015

Background: Ginsenoside Rd (GSRd), one of the most abundant ingredients of Panax ginseng, protects the heart via multiple mechanisms including the inhibition of $Ca^{2+}$ influx.We intended to explore the effects of GSRd on L-type $Ca^{2+}$ current ($I_{Ca,L}$) and define the mechanism of the suppression of $I_{Ca,L}$ by GSRd. Methods: Perforated-patch recording and whole-cell voltage clamp techniques were applied in isolated rat ventricular myocytes. Results: (1) GSRd reduced $I_{Ca,L}$ peak amplitude in a concentration-dependent manner [half-maximal inhibitory concentration $(IC_{50})=32.4{\pm}7.1{\mu}mol/L$] and up-shifted the current-voltage (I-V) curve. (2) GSRd ($30{\mu}mol/L$) significantly changed the steady-state activation curve of $I_{Ca,L}$ ($V_{0.5}:-19.12{\pm}0.68$ vs. $-6.26{\pm}0.38mV$; n = 5, p < 0.05) and slowed down the recovery of $I_{Ca,L}$ from inactivation [the time content (${\zeta}$) from 91 ms to 136 ms, n = 5, p < 0.01]. (3) A more significant inhibitive effect of GSRd ($100{\mu}mol/L$) was identified in perforated-patch recording when compared with whole-cell recording [$65.7{\pm}3.2%$ (n = 10) vs. $31.4{\pm}5.2%$ (n = 5), p < 0.01]. (4) Pertussis toxin ($G_i$ protein inhibitor) completely abolished the $I_{Ca,L}$ inhibition induced by GSRd. There was a significant difference in inhibition potency between the two cyclic adenosine monophosphate elevating agents (isoprenaline and forskolin) prestimulation [$55{\pm}7.8%$ (n = 5) vs. $17.2{\pm}3.5%$ (n = 5), p < 0.01]. (5) 1H-[1,2,4]Oxadiazolo[4,3-a]-quinoxalin-1-one (a guanylate cyclase inhibitor) and N-acetyl-$\small{L}$-cysteine (a nitric oxide scavenger) partly recovered the $I_{Ca,L}$ inhibition induced by GSRd. (6) Phorbol-12-myristate-13-acetate (a protein kinase C activator) and GF109203X (a protein kinase C inhibitor) did not contribute to the inhibition of GSRd. Conclusion: These findings suggest that GSRd could inhibit $I_{Ca,L}$ through pertussis toxin-sensitive G protein ($G_i$) and a nitric oxide-cyclic guanosine monophosphate-dependent mechanism.

• Korean journal of applied entomology
• /
• v.59 no.2
• /
• pp.145-152
• /
• 2020

The populations of Polyphagostarsonemus latus (Acari: Tarsonemidae) peaked two times on green perilla grown in greenhouses of Geumsan-Gun, Chungchungnamdo. The first peak of P. latus was in the middle of June, after it was first detected in late May. The population of P. latus peaked for the second time in mid July as its density stared rapidly increasing in early July. The application of chemical pesticides and eco-friendly agricultural materials, the two management methods used to control P. latus on green perilla, did not alter the occurrence patterns of P. latus; population size of the mite was much larger in greenhouses using chemical pesticides than in the ones using eco-friendly agricultural materials. This difference might be cuased by continuity of the management methods. Chemical control of P. latus should be limited owing to pesticide residue. The highest density of P. latus on green perilla plants was observed after 25 days after inoculation. The density was the highest in mid-aged leaves (e.g., the largest leaves) and the lowest in newly developed leaves (e.g., smallest leaves). However, there was no significant (P > 0.05) correlation between leaf size and density of P. latus. These results indicate that leaf size (e.g., leaf age) did not affect the occurrence of P. latus. Thus, any leaf of a green perilla plant is available as a sample unit for P. latus.

• Korean journal of applied entomology
• /
• v.39 no.1
• /
• pp.21-24
• /
• 2000

These studies were conducted to investigate the effect of temperature on the developmentof Delia platura (Meigen) under a laboratory condition at five different temperatures. The developmentalperiods of D. platurcr from egg to adult emcrgence at the temperatures of 11, 15, 19, 23, and 27$^{\circ}$C were67.8k 14.5, 43.7t-9.4, 31.2-t-7.0, 22.4k4.9, and 18.3k4.1 days, respectively. Based on these results,threshold temperature of development and effective cumulative degree-day (DD) for overall developmentwas 0.6"C and 579.8 DD, respectively. Generation of time D. pluturci averaged 30.8 days, and meannumber of eggs produced per female was 246.5 k 16.9 at 23$^{\circ}$C. Hatching rate and emergence rate curvesin relation to the temperature was dome shaped with the peak of 90.0 and 85.2% at 23"C, it wassuggesting that hatching and emergence were inhibited by high temperature above that temperature.Pupation rate of the insect reared on garlic and on onion were higher than those reared on other diets.Oviposition of D. platum usually began 7-9 days after emergence at 23$^{\circ}$C. Females laid about 3-4 eggsin a day. Oviposition of the females peaked at the age of 12- 18 days after emergence. of 12- 18 days after emergence.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.20 no.1
• /
• pp.58-63
• /
• 2010

The glass-ceramics made from the mixture of coal bottom ash, produced from a thermal power plant mixed with $Na_2O$ and $Li_2O$ was fabricated and their crystallization behavior was studied using a non-isothermal analyzing method. The temperature for 50% crystallization was higher than the exothermic peak temperature $T_p$ at DTA curve and the quickest crystallization temperature was much the same as $T_p$ as identified from the relationships of crystallized fraction and crystallization rate with temperature. By using Kissinger equation describing a crystallization behavior, the activation energy (262 kJ/mol), the Avrami constant (1.7) and the frequency ($5.7{\times}10^{16}/s$) for crystallization were calculated from which the nepheline crystal could be expected as showing an 1~2-dimensional surface crystallization behavior mainly with some bulk crystallization tendency at the same time. The actual observation of microstructure using SEM showed the considerable amount of surface crystals of dendrite and the bulk crystals with low fraction, so the prediction by the Kissinger equation was in accord with the crystallization behavior of glass-ceramics fabricated in this study.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.20 no.1
• /
• pp.53-57
• /
• 2010

The influence of CaO addition on the crystallization temperature, crystal types, and microstructure of L-A-S ($Li_2O-Al_2O_3-SiO_2$) glass-ceramics system fabricated from a coal bottom ash, produced at thermal power plant, was studied. The glass transition and crystallization temperatures were shifted to the higher temperature position with increasing CaO content in a non-isothermal analysis using a DTA. The major crystalline phases of L-A-S glass-ceramics system produced were identified as ${\beta}$-spodumene ($LiAlSi_2O_6$) and eucryptite ($LiAlSiO_4$). The glass-ceramics showed a bulk and surface crystallization behavior at a time. With increasing CaO content, the ${\beta}$-spodumene peak in XRD increased and some CaO-related phases were formed. The surface crystal grown from the exterior to the center in glass-ceramics showed various shapes by amount of CaO added. Some cracks were generated at the glass-ceramics containing CaO above 9 wt% due to the mismatch of thermal expansion coefficients between a ${\beta}$-spodumene and CaO-related crystal phases.

• Korean Journal of Clinical Pharmacy
• /
• v.8 no.2
• /
• pp.83-88
• /
• 1998

Improved knowledge of the time course of antimicrobial activity should provide useful information for designing optimal dosage regimen. In contrast to $\beta$-lactam, aminoglycosides tend to induce a prolonged postantibiotic effect against aerobic or facultative gram negative rods and clinical outcome was significantly correlated with achieving peak serum concentrations. The objective of this study was to compare the efficacy, safety of e same total daily dose of amikacin and gentamicin given either twice or thrice daily in the treatment of patients. Consecutive patients over 20 years old with a suspected or confirmed infection for which an aminoglycosides was indicated were eligible. Exclusion criteria were known allergy to aminoglycosides, renal impairment, granulocytopenia and pregnancy. Patients were treated with intravenous amikacin 15 mg/kg/day or gentamicin 4.5 mg/kg/day either in two devided or in three devided. Seventy-four patients with infection were enrolled in this study of amikacin twice daily (A2, n=29), gentamicin twice daily (G2, n=8) vs amikacin thrice daily (A3, n=30), gentamicin thrice daily (G3, n=7). Baseline characteristics were comparable in G2 and G3. The clinical cure rate (including partial improve) were $89.0\%\;and\;86.0\%$ in A2 group and A3 group respectively. The bacteriologic cure rate were $99.0\%\;and\;85.7\%$ in A2 group and in A3 group respectively. The clinical and bacteriologic effects were difficult to compare G2 with G3, because of the small numbers of patients. The serum creatinin rose in $3.44\%$ (1 in 29) of patients in the A2 group compared to $13.3\%$ (4 in 30) in e A3 group. Although audiometry was not performed, there was no clinical evidence of ototoxicity in any of the patients. In our opinion, twice-daily regimen of aminoglycosides is more effective and less nephrotoxic than thrice-daily regimen.

• Journal of Environmental Science International
• /
• v.11 no.4
• /
• pp.347-353
• /
• 2002

This study was conducted to investigate the characteristics of chloramination as a secondary disinfection in a drinking water distribution system. At the range from pH 6 to pH 8, monochloramine was predominant with a trace of dichloramine, and the free chlorine was detected after breakpoint. At $25^{\circ}C$, the breakpoints of pH 6, 7 and 8 appeared when the weight ratios of chlorine to ammonia nitrogen were 11:1, 9:1 and 10:1 respectively, and the peak points on the breakpoint curves at pH 6, 7 and 8 were in the Cl$_2$ / NH$_3$-N ratio of 9:1, 6:1 and 5:1 respectively. As pH increased from 6 to 8, maximum point of monochloramine on the breakpoint curve was moved from 7:1 to 5:1 in the weight ratio of chlorine to ammonia nitrogen. The maximum concentration of monochloramine was formed at the pH values of 7~8 and in the Cl$_2$ / NH$_3$-N ratio below 5:1. As the Cl$_2$/NH$_3$-N ratio increased and the pH lowered, chloramines decay proceeded at an increased rate, and residual chloramines lasted longer than the residual free chlorine. The monochloramine and the dichloramine were formed at pH 6, and then the dichloramine continued increasing with contact time.

• Journal of the Korean earth science society
• /
• v.30 no.6
• /
• pp.734-743
• /
• 2009

In order to examine how climatological condition can influence on urban scale particulate air pollutants, single and cross spectrum analysis have been performed to daily mean concentrations of particulate matters ($PM_{10}$) in Busan together with the climatological variables over the Asian dust source regions. Single power spectrum analysis of $PM_{10}$ concentrations in Busan shows that, aside from the typical and well-known periodicities, 3-4 year of peak periodicity of power spectrum density was identified. In cross spectrum analysis, this 3-4 year periodicity is found to have a strong positive correlation with the wind speed and pressure, and negative with the temperature and relative humidity, which is rather consistent with both characteristics of air mass during the Asian dust event whose periodicities have been recorded inter-annually over the Korean urban cities. Over the Asian dust source regions, $PM_{10}$ vs. precipitation shows no significant periodicity from the time series of precipitation data, but the periodicity of EDI (Effective Drought Index) shows some interannual variabilities ranging from 2 to 4 years over the various source regions, suggesting that, rather than precipitation itself, the EDI could be more closely associated with the occurrence frequency of Asian dust and interannual variability of urban particle concentrations in Korean cities.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.19 no.3
• /
• pp.265-286
• /
• 1997

Bone morphogenetic proteins(BMPs) are a group of transforming growth factor beta(TGF-${\beta}$)-related factors and multifunctional proteins, especially the only known biologic factors capable of inducing endochondral bone formation at an extraskeletal site. This study was performed to investigate the effect of the partially purified porcine BMP(pBMP) at an ectopic site. PBMP was partially purified from porcine bone matrix and its activity was monitored by an in vivo bioassay. The purification method utilized extraction of the bone-inducing activity with 4M guanidine, followed by chromatography on heparin-Sepharose. Active fractions were assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. And the fractions were reconstituted with inactive insoluble collagenous bone matrix from rats, acid soluble type I collagen from rat tail and chondroitin-6-sulfate sodium salt and implanted into the pectroralis muscle pouches of Sprague-Dawley rats. And the carrier complex was implanted on the opposite side as control. The rats were sacrificed at the day of 1st, 3rd, 5th, 7th, 11th, 14th and 21st after implantation and examined histologically, radiologically and biochemically. And alkaline phosphatase activity and calcium content were used as indices of bone formation. The results were as follows ; 1. Active fractions were localized in a zone between 31 and 40 KDa on SDS-PAGE. 2. The implanted 3.0mg of the partially purified pBMP induced cartilage and bone in the muscle tissue of rats through an endochondral ossification process. 3. Inactive insoluble bone matrix, type I collagen and chondroitin-6-sulfate have functioned as carriers for pBMP, but revealed some foreign body reactions. 4. Soft X-ray didn't reveal significant change between the experimental and the control group. 5. The alkaline phosphatase activities in the experimental group of 5th, 7th, 11th, 14th and 21st were increased significantly compared with control (p<0.01) with the peak in the group of 11th day. 6. With time, the calcium content of the experimental group increased. And the calcium contents in the experimental group of 11th, 14th and 21st were increased significantly compared with control (p<0.01).