• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.2
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• pp.120-130
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• 2012

Objectives: The purpose of this study is to investigate the symptoms accompanied with acne and HRV pattern of the acne patients. Methods: We reviewed 60 acne patients(age 15-38) who visited ${\bigcirc}{\bigcirc}$ hospital from January 2010 to October 2011. We investigated the symptoms accompanied with acne of 60 patients and evaluated HRV of 41 acne patients. The data were analyzed by Mann-Whitney test using SPSS/PC ver 13.0 program. Results: 1. Prevalence of female post-adolescent acne was 66.7% in this study. The symptoms accompanied with acne were dischezia(35%), gastric discomfort(28.3%) in all patients and dysmenorrhea(40%), leukorrhea(38%), irregular menstrual period (24%) in female patients. 2. SDNN, RMSSD, VLF and HF of female were significantly lower than male. 3. SDNN, TP and VLF of un-dysmenorrhea group were significantly lower than dysmenorrhea group. 4. PSI of under 6 months group was significantly higer than over 6 months group. 5. In postadolescent acne patients SDNN, RMSSD, TP, LF and HF were significantly lower and PSI was significantly higher than adolescent acne patients. Conclusions: There are many female post-adolescent acne pateints and the assessment of the symptoms accompanied with acne and stress degree is helpful in treating acne. The further research and development about the diagnostic and therapeutic methods of acne are needed in oriental obstetrics and gynecology field.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.95-104
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• 2011

Objectives: The purpose of this study is to investigate the relationship between the degree of menopausal symptom and granulocyte/lymphocyte ratio, and heart rate varibility(HRV). Methods: From 11th April 2011 to 20th May 2011, a total 30 female subjects (age 41-60) was recruited. We evaluated the degree of menopausal symptoms by Kupperman' s index and measured subject's WBC differential count and HRV. The data were analyzed by Kruskal-Wallis test and Spearman correlation test using SPSS/PC ver 13.0 program. Results: 1. There was no statistically significant difference in granulocyte/lymphocyte ratio and HRV among 4 classified groups according to Kupperman's index.- Mild, Moderate, Severe and Urgent. 2. Granulocyte ratio and general symptom score(within Kupperman's index) significantly showed negative correlation coefficient(r=-0.499, p=0.005), and Lymphocyte ratio and general symptom score significantly showed positive correlation coefficient (r=0.374, p=0.042). 3. Granulocyte/lymphocyte ratio and HRV showed no significant correlation. Conclusions: There was no significant relation among the degree of menopausal symptoms and granulocyte/lymphocyte ratio, and HRV. But furthermore large scale study is required.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.10
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• pp.479-486
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• 2017

Recently, GPGPU has been able to increase the degradation of computer performance, and it is now possible to run physically based real-time simulations on PCs that require high computational complexity. Physical calculations applied in physics simulation can be performed by parallel processing, and can be efficiently performed using parallel computation using Compute shader recently supported by OpenGL 4.3 and Unity 4.0. In this paper, we measure and compare the number of performance in real - time physics simulation in OpenGL running on various platforms and Unity, a content creation tool supporting various platforms. Particle simulation experiments show that particle simulation using Unity performs faster than 136.04%. It is expected that it will be able to select better development tools for future multi - platform support.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.13 no.2
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• pp.304-311
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• 2006

Purpose: This study was done to examine the relation of self-reported adult attachment style, perceived parental rearing styles and anger in undergraduate students. Method: The six hundred and fifty undergraduate students participating in this descriptive correlational design study were conveniently sampled from K University and S College located in Seoul, Korea. The instruments were Spielberger's state-trait anger expression inventory - Korean version(Chon, Han, Lee & Spielberger, 1997), the instrument for measuring attachment styles by Hazen and Shaver (1987), and Hong's instrument for measuring parental rearing style(2001). Data were analyzed by descriptive statistics, t-test, $X^2-test$, ANOVA, and cluster analysis using pc-SAS(version 8.0e) program. Results: The mean scores for trait anger and anger-in were higher in undergraduate students with insecure and ambivalent attachment style compared to students with a secure attachment style. The mean score for anger-control was highest in undergraduate students with a secure attachment style. The parental rearing styles by cluster analysis were grouped as Neglect, Permissive, Democratic, and Protective-control. The mean scores for trait anger, anger-in, and anger-out were higher in undergraduate students with 'Neglect' parental rearing style than in those with 'Democratic' and 'Protective-control' rearing styles. Conclusion: Trait anger and anger expression might be related to an attachment style and/or a parental rearing style.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.64-64
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• 2018

하천에서 수위는 가장 기본적인 수리 수문학적 자료로서, 홍수나 가뭄 등의 피해를 막기 위한 치수와 물을 잘 통하게 하거나 물을 이용하기 위한 이수에 주로 사용된다. 예를 들면, 댐, 보, 저수지 등의 하천시설물 설계 및 관리를 위해 수위를 이용하며, 유량 산정을 위해서 수위-유량 관계 곡선식을 구축하여 수위를 이용한다. 따라서 하천에서 수위는 현재 국내에서 수자원분야에서 사용되는 자료 중에서 가장 중요하며, 동시에 광범위하게 사용되고 있으므로 수위를 관측하는 것이 수자원의 기초라 할 수 있다. 수위 관측의 필요성과 확장 필요성에 대한 인식에도 불구하고, 국내의 수위 관측소는 한강, 낙동강, 금강 등 대하천 위주로 설치되어 있어, 중소규모 하천에서 발생하는 다양한 수문사상에 대한 분석 및 예측이 어려운 실정이다. 특히, 홍수의 경우 같은 강우 사상에도 대하천보다는 중소규모의 하천이 더 극단적으로 유출이 발생하기 때문에, 즉각적인 수위의 계측이 필요한 실정이다. 하지만 한정된 예산 및 인프라의 부족은 중소규모 하천에 대한 수위 관측 시스템의 적용이 대하천에 비해 그 우선수위가 밀리는 원인이 되고 있으며, 지속적으로 중소규모 하천에 대한 수위 관측시스템 적용에 대한 수요가 증가를 야기 시키고 있다. 최근, 과거에 제품을 만들기 위한 전자회로, 자재명세서, 기판도면 등의 정보를 공개하지 않는 폐쇄적인 환경을 벗어나 제품을 만들기 위한 하드웨어 정보를 공개하고, 공개된 정보를 통해 기술을 개발하기 위한 움직임이 활발하다. 이러한 개념을 오픈소스 하드웨어라는 개념으로서, 하드웨어의 제작 없이 간단한 코딩을 통해 하드웨어를 컨트롤 하는 기술이다. 즉, 오픈소스 하드웨어는 초소형화된 PC를 활용하여 센서를 작동하는 것이라 할 수 있다. 이를 통해 기존의 기술을 저렴한 가격으로 제품으로 생산할 수 있다. 또한 사물인터넷(IOT)를 활용하여 온라인 상에서 이러한 오픈소스 하드웨어를 컨트롤 할 수 있으며, 웹서비스와 결합할 경우 센서를 통해 수집된 결과를 인터넷 상에서 확인 할 수 있는 기술들이 지속적으로 개발하고 있다. 이러한 기술이 접목되면 과거에 비해 적은 비용으로 고효율의 자료 수집을 수행 할 수 있다. 본 연구에서는 지속적으로 증가하고 있는 중소규모 하천에 대한 수위 관측시스템 적용에 대한 수요를 해결하기 위해서 기존의 시스템이 가지고 있는 경제적, 기술적 한계를 극복하기 위하여 오픈소스 하드웨어 플랫폼인 아두이노와 사물인터넷 기반 기술을 활용하기 위한 웹서비스를 이용하여 실시간 수위 관측기술을 개발하고, 적용성을 검토하고자 한다.

• Journal of Adhesion and Interface
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• v.4 no.1
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• pp.9-17
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• 2003

The UV hard coating materials are attracting more and more attention to modern industry, in terms of the development of low or non solvent coating materials which will contribute to economizing both materials and energy and to reducing pollution. This study was performed in order to invent UV curable coating materials containing colloidal silica which have actual industrial applications. As results of experiments, the oligomers type and the concentration of colloidal silica acrylate oligomer (SAOC) have an influence on various especially, The properties of UV hardening cooling, such as chemical, abrasion resistance and weatherability, were greatly enhanced, the impact properties of coated polycarbonate substrate were improved compared with the noncoated that. The UV cured films containing 30 wt% SAOC obtained showed the best properties.

• The Journal of Korean Obstetrics and Gynecology
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• v.33 no.1
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• pp.19-35
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• 2020

Objectives: The purpose of this study was to show effectiveness of Acupuncture treatment on gastrointestinal dysfunctions after Cesarean section by analyzing randomized controlled clinical trials. Methods: We searched randomized controlled clinical trials related with acupuncture treatment on gastrointestinal dysfunctions after Cesarean section through national and overseas database and analyzed them in detail. Results: 6 articles were included according to our selection criteria and 1,084 women were involved. 3 studies used TEAS (Transcutaneous Electrical Acupoint Stimulation), 2 studies used Elastic band and 1 study used Acupressure by hand. Their results were statistically more effective than control groups. The most frequently used acupoints were Neiguan (PC6), Zusanli (ST36) followed by Sanyinjiao (SP6), Hegu (IL4). Conclusions: There was significant difference in the effectiveness of the intervention including Acupuncture treatment. Based on analysis, it could be an effective way for the treatment of gastrointestinal dysfunctions after Cesarean section in clinical practice.

• The Journal of Internal Korean Medicine
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• v.40 no.1
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• pp.70-88
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• 2019

Objective: This study investigated the trends in pancreatic cancer research on Korean medicine in order to establish a direction for further study. Methods: Pancreatic cancer research on Korean medicine was reviewed using databases such as OASIS, KoreanTK, KISS, RISS, KISTI, and NDSL. The search terms were "pancreatic cancer" "Korean medicine," and "herbal medicine." There was no restriction on publication dates, and the reviewed studies were analyzed according to the type of research. Results: Nineteen studies were reviewed. The numbers and types of research were as follows: 9 clinical studies including case reports, 2 review studies, and 8 in vitro studies; there was no in vivo study. Among the clinical research were 3 descriptive studies and 6 case reports. The baseline characteristics and quality of life of pancreatic cancer patients were analyzed in the descriptive studies. In the case reports, interventions such as herbal medicine, pharmacopuncture, and acupuncture were used. Research articles on the review of pancreatic cancer were titled "Preliminary Study for Development of Korean Medicine Clinical Practice Guideline for Pancreatic Cancer" and "Systemic Review on the Tumor Dormancy Therapy." Cell lines such as PANC-1, MIA PaCa-2, and AsPC-1 were used for in vitro studies. These studies have reported decreased cell viability, induced apoptosis, and changes in cancer-related gene expression. Conclusion: Through this review, we found that using Korean medicine for treating pancreatic cancer is applicable. However, due to overall limited the number of study, the benefit of Korean medicine for pancreatic cancer may be substantiated to a limited degree. Better methodological quality and large controlled trials are expected to further quantify the therapeutic effect of Korean medicine.

• Korean Journal of Acupuncture
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• v.36 no.2
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• pp.93-103
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• 2019

Objectives : The aim of this study is to review the current trends in experimental studies on the acupuncture moxibustion treatment for visceral hypersensitivity. Methods : PubMed was searched for experimental studies about visceral hypersensitivity and acupuncture/moxibustion. Data were extracted and tabulated from the selected articles about experimental method, intervention, result and mechanism. Results : Total 23 articles were reviewed. Chronic visceral hypersensitivity animal model was applied in 17 studies (74%). Visceral hypersensitivity was measured by abdominal withdrawal reflex scoring or/and abdominal electromyogram. Acupoints like ST25, ST36, ST37, BL25, LI11, BL32 and PC6 were treated by electroacupuncture or moxibustion. All articles reported that electroacupuncture or moxibustion treatment is significantly effective in reducing visceral hypersensitivity. Treatment mechanisms were studied, related to mast cell, serotonin (5-HT) and receptor (5-HT3R and 5-HT4R), substance P (SP), vasoactive intestinal polypeptide (VIP), c-fos positive cell, corticotropin-releasing hormone (CRH), purinergic 2X (P2X)2, P2X3, P2X4, P2X7, N-methyl-D-aspartate (NMDA) receptor (NR1 and NR2B), prokinectin (PK) 1 and PK2. Conclusions : Evidences on acupuncture/moxibustion treatment for visceral hypersensitivity in animal studies warrant more research on effective acupoins, electro-acupuncture methods and treatment durations.

• Journal of fish pathology
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• v.34 no.1
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• pp.23-29
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• 2021

Interferon regulatory factors (IRFs) are a family of transcription factors essential to the control of antiviral immune response, cell growth, differentiation and apoptosis. IRF10 of zebrafish (Danio rerio) was negative regulation of the interferonΦ1 and 3 response in vitro. In this study, we analyze the induction of in vivo immune response activation from the IRF10 gene of zebrafish and the protective effect against VHSV. As the results, the group inoculated with IRF10 expression vectors, there was no expression of IFNΦ1, suggestion that IRF10 may function as a negative regulator of IRF3, which binds to the IFNΦ1 promoter. And other types of interferon genes (IFNΦ2-4) are thought to have been activated, inducing to the expression of pro-inflammatory cytokine and Mx genes. As the results of challenge test performed at 14 days after inoculation of the expression vectors, the maximum survival rate [50% (1㎍ DNA) and 42.5% (10㎍ DNA)] for IRF10 group were recorded. Meanwhile, the survival rates of pcDNA3.1 and PBS as the control groups were 10% and 15%, respectively. This study suggests that the possibility that activation of IRF10 molecule could be exploited as a VHS control method.