• Journal of Korea Multimedia Society
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• v.19 no.12
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• pp.2014-2023
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• 2016

Web presence is one of the key issues for extensive deployment of Internet-of-Things (IoT). An obstacle to overcome for Web presence is relatively low computing power of IoT devices. In this paper, we present implementation of an IoT platform based on Constrained Application Protocol (CoAP) which is a web transfer protocol proposed by Internet Engineering Task Force (IETF) for the low performance IoT devices such as Wireless Sensor Network (WSN) nodes and micro-controllers. To qualify the performance of CoAP-based IoT system for such an application as smart grid, we designed a test platform consisting of Raspberry Pi2, Kmote WSN node and a desktop PC. Using open source softwares, CoAP was implemented on top of the platform. Leveraging the GET command defined at CoAP specification, performance of the system was measured in terms of round-trip time (RTT) from web application to the Kmote sensor node. To investigate abnormal cases among the test results, hop-by-hop delays were measured to analyze resulting data. The average response time of CoAP-based communication except the abnormal data was reduced by 23% smaller than the previous research result.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.22 no.4
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• pp.61-67
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• 2008

In this papar, the flow meter system for pulverized coal is developed for the pulverizer-burner system of the boiler or the blast furnace. The sensor of the system a lied the capacitance with a pair of electrode on the outer wall of the electric insulator pipe. The circuit is designed for the measurement of the granule flow density combining as a measuring electrode and a reference. In order to measure granule-flow density, the calibration curve between the weight measured from loadcell and the voltage from the circuit is created. It is verified that the flow meter system has reliability and accuracy using on-line test.

• Journal of Microbiology and Biotechnology
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• v.30 no.4
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• pp.604-614
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• 2020

The application of steroids has steadily increased thanks to their therapeutic effects. However, alternatives are required due their severe side effects; thus, studies on the activities of steroid derivatives are underway. Sugar derivatives of nandrolone, which is used to treat breast cancer, as well as cortisone and prednisone, which reduce inflammation, pain, and edema, are unknown. We linked O-glucose to nandrolone and testosterone using UDP-glucosyltransferase (UGT-1) and, then, tested their bioactivities in vitro. Analysis by NMR showed that the derivatives were 17β-nandrolone β-ᴅ-glucose and 17β-testosterone β-ᴅ-glucose, respectively. The viability was higher and cytotoxicity was evident in PC12 cells incubated with rotenone and, testosterone derivatives, compared to the controls. SH-SY5Y cells incubated with H₂O₂ and nandrolone derivatives remained viable and cytotoxicity was attenuated. Both derivatives enhanced neuronal protective effects and increased the amounts of cellular ATP.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.2
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• pp.139-144
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• 2012

It has been reported that activation of metabotropic glutamate receptor 1 (mGluR1) can mediate endocannabinoid-induced short-term depression of synaptic transmission in cerebellar parallel fiber (PF)-Purkinje cell (PC) synapse. mGluR1 has signaling pathways involved in intracellular calcium increase which may contribute to endocannabinoid release. Two major mGluR1-evoked calcium signaling pathways are known: (1) slow-kinetic inward current carried by transient receptor potential canonical (TRPC) channel which is permeable to $Ca^{2+}$; (2) $IP_3$-induced calcium release from intracellular calcium store. However, it is unclear how much each calcium source contributes to endocannabinoid signaling. Here, we investigated whether calcium influx through mGluR1-evoked TRPC channel contributes to endocannabinoid signaling in cerebellar Purkinje cells. At first, we applied SKF96365 to inhibit TRPC, which blocked endocannabinoid-induced short-term depression completely. However, an alternative TRP channel inhibitor, BTP2 did not affect endocannabinoid-induced short-term depression although it blocked mGluR1-evoked TRPC currents. Endocannabinoid signaling occurred normally even though the TRPC current was mostly blocked by BTP2. Our data imply that TRPC current does not play an important role in endocannabinoid signaling. We also suggest precaution in applying SKF96365 to inhibit TRP channels and propose BTP2 as an alternative TRPC inhibitor.

• Journal of KIISE:Computer Systems and Theory
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• v.33 no.4
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• pp.205-215
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• 2006

Pen-input displays, such as LCD tablets and tablet PCs, are already popular for its usability in CAD design, in particular. in concept design phase. We propose an intuitive B-Spline modification scheme that can be used for the CAD systems targeting for such devices. Differently from the control point based modification schemes for the B-splines, our scheme relates user pen marking to determining the final shape of the target curve and surface. This, eventually, reduces time for interacting with the shape parameters (i.e., by control points or direct manipulators), which has been regarded as an unavoidable routine tasks for design. To prove its usability, we made an experiments with selected subjects who have been working for industrial design.

• Journal of the Korean Society of Safety
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• v.31 no.4
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• pp.35-41
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• 2016

In order to guarantee the process safety and prevent accidents, the deviations from normal operating conditions should be monitored and their root causes have to be identified as soon as possible. The statistical theories-based method among various fault diagnosis methods has been gaining popularity, due to simplicity and quickness. However, according to fault magnitudes, the scalar value generated by statistical methods can be changed and this point can lead to produce wrong information. To solve this difficulty, this work employs PCA (Principal Component Analysis) based method with qualitative information. In the case study of our previous study, the number of assumed faults is much smaller than that of process variables. In the case study of this study, the number of predefined faults is 19, while that of process variables is 6. It means that a fault diagnosis becomes more difficult and it is really hard to isolate a single fault with a small number of variables. The PCA model is constructed under normal operation data in order to get a loading vector and the data set of assumed faulty conditions is applied with PCA model. The significant changes on PC (Principal Components) axes are monitored with CUSUM (Cumulative Sum Control Chart) and recorded to make the information, which can be used to identify the types of fault.

• Proceedings of the KIPE Conference
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• 2004.07a
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• pp.129-132
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• 2004

A guard lamp system has been installed at the PV positive center, located at Gwangju in Korea. Digital environment that is represented to internet is displacing business way of industry and business achievement way with the fast speed being giving great change on life whole, improve existence business process utilizing internet and Web connection technology, information superhighway to tradition industrialist manufacture and e-transformation's propulsion that wish to maximize productivity and administration efficiency is spread vigorously. In this paper, we wish to accomplish generation equipment's heighten stability and believability through remote monitoring and control of guard lamp system. This paper describes the design of the monitoring system for the sensing data and indirect controlling of the guard lamp system. Most of the conventional monitoring systems depend on the special hardware and software. The essential design of monitoring system is to provide the convenience for the user and the portability for the system. In order for the system to fulfill its requirements, it was designed using Labview GUI facility based on the Windows 2000 environment of IBM PC compatible and Add-oncard based on the TCP/IP protocol. Advantage of the monitoring system are a personnel expenses curtailment effect, of the place restriction and unmanned system of the generationplants, etc..

• Proceedings of the KIPE Conference
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• 2008.06a
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• pp.259-261
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• 2008

The electronic products such as laptop PC, cellular phone, robots and etc. need the DC power source. Recently, the secondary battery is frequently used as the portable DC power source and it needs forming process. In this paper, we proposed the bidirectional converter that the battery can be charged with high power factor and the discharged energy is regenerated into AC power source. In the charging mode, the converter acts as the boost rectifier. And the AC input current is controlled in phase with the AC input voltage. As a result, the power factor is improved nearly to unity. In the discharging mode, the DC power of battery wasted in resistor is regenerated to the AC bus line. Finally, the validity of the proposed bidirectional converter is verified by computer simulations and experimentation.

• Fisheries and Aquatic Sciences
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• v.7 no.2
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• pp.70-75
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• 2004

The CMV promoter driven lacZ reporter gene (pcDNA-lacZ) was constructed and used for DNA immunization study. The expression of the lacZ gene was confirmed in vitro using RTG-2 cell line before using for in vivo study in olive flounder (Paralichthys olivaceus). In the dose response study, the maximum expression of the lacZ gene was found in the group injected with 5 ${\mu} g$ of the plasmid DNA. Kinetic study showed a significantly increased expression of $\beta-galactosidase$ gene at 7 days after injection. Effects of DNA vaccine on specific and nonspecific immune responses such as antibody and NO production were studied and the significant effect was found in olive flounder injected with 10 and 15 ${\mu} g$ DNA (sub optimal dose for lacZ gene expression). Two pro inflammatory cytokine genes, $IL-l\beta$ and $TNF-\alpha$, were also found to be up regulated in the muscle injected with the plasmid, suggesting an induction of local inflammatory response.

• Journal of Korea Game Society
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• v.20 no.1
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• pp.133-142
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• 2020

Digital educational game market is growing as it expands to smart platforms such as smart phones and tablet PCs. As games have become digital in the classroom evolving to two-ways. In this paper, it designed that enables elementary students to acquire musical knowledge related to musicians through digital board games. By collecting achievement cards of musicians associated with. Elementary students repeatedly gain relevant musical knowledge in the end. The developed game was simulated using Petri net to check the gameplay flow.