• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.10
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• pp.2272-2278
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• 2011

The company which have deep-sea fishing vessel have to improve their voyage dashboard that was operating by manually to grasp sailing information of fishing vessel. This thesis design sailing information that is ship location on the globe, a catch of fish, and line of longitude and latitude to display on the map more visually by using on-line PC or DID (Digital Information Display). Thesis considered about designing web application which is available to visualize sailing information of 37 deep-sea fishing vessels in operation by using Flash-based RIA technology. This system was improving operator's and administrator's satisfaction of using information because, It make possible not only to grasp status of many vessels in one display but also to monitoring situation and deciding process.

• The Korea Journal of Herbology
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• v.26 no.3
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• pp.75-82
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• 2011

Objectives : In this study, we evaluated the effect of Chungganhaeju-hwan(CGHJH) on hydrogen peroxide($H_2O_2$)-induced and ethanol(EtOH)-induced neuronal damage in vitro and in vivo, respectively. Methods:We carried out the anti-oxidant effects of CGHJH against hydrogen peroxide($H_2O_2$)-induced toxicity in HT22 and PC12 cells using thiazolyl blue tetrazolium bromide. Then, to investigate the protective effect on CGHJH against EtOH-induced memory impairment and hippocampal cell damage in male ICR mice, we performed novel object recognition test(NORT), and analysed the brain tissues after immunohistochemistry and western blotting. Results:CGHJH showed protective effect from $H_2O_2$-induced cell toxicity at doses of $1\sim100{\mu}g$/mL in both HT22 and PC12 cells. CGHJH had also recovery effect from EtOH-induced memory impairment in ICR mice from NORT and it protected hippocampal cells against EtOH toxicity in the result of cresyl violet and NeuN immunoreactivity. Conclusion : These results demonstrate that CGHJH has protective effect in neuronal cells against $H_2O_2$ and EtOH toxicities and this effect could be a main role of recovery effect on EtOH-induced memory loss.

• Animal cells and systems
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• v.1 no.1
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• pp.81-86
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• 1997

We studied the mechanism of arachidonic acid on the secretion of a neurotransmitter in rat pheochromocytoma PC12 cells. Arachidonic acid inhibited the 70 mM $K^+$-induced secretion of norepinephrine. Arachidonic acid also inhibited the 70 mM $K^+$-induced $Ca^{2+}$ mobilization which is due to the opening of the voltage-sensitive $Ca^{2+}$ channels (VSCC). Both the half maximal inhibitory concentration ($IC_{50}$) of the norepinephrine secretion and VSCC coincided at 30 uM. The major oxidized metabolites of arachidonic acid, prostaglandins did not mimic the inhibitory effect of arachidonic acid. Nordihydroguaiaretic acid (NDGA) and indomethacin which are inhibitors of lipoxygenase and cyclooxygenase, respectively, did not block the inhibitory effect of arachidonic acid. The results suggest that arachidonic acid serves as a signal itself, not in the form of metabolites. The pretreatment of various $K^+$ channel blockers such as 4-aminopyridine, tetraethylarnmonium, glipizide, or glibenclamide also did not show any effect on the inhibitory effect of arachidonic acid. Through these results we suggest that arachidonic acid regulates VSCC directly and affects the secretion of neurotransmitters.

• Journal of the Korean Society for Railway
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• v.19 no.1
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• pp.1-10
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• 2016

To improve the sound insulation performance of laminated glass in high speed trains, it is beneficial to study the relationship between the characteristics of interlayer films and the acoustical performance. In addition to those of conventional PVB (polyvinyl butyral), the dynamic mechanical properties of PVB derivatives and PC (polycarbonate), which are candidates for interlayer films, were analyzed. We assumed that PVB-HEMU, which has a glass transition temperature ($T_g$) around room temperature and a large tan ${\delta}$ (loss tangent) value, can be made to damp efficiently. The damping capability was tested utilizing sound transmission loss measurement and simulation under the identical structure of laminated glass in high speed trains. We also built a database for analysis of relations between interlayer film characteristics and acoustical performance; this was followed by the determination of sound transmission loss using the intensity technique and FEA.

• Proceedings of the KSR Conference
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• 2008.06a
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• pp.1773-1780
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• 2008

When the fire occur in the deeply underground subway station, the difficulties of passenger evacuation are expected because of many stairs to the exit. In this study, SOONGSIL-University station (7 line, 47m depth) is the one of the deepest subway stations of the each line in the Seoul metro. The numerical computational-simulation was performed for the fire driven flow in the subway station. Hot and smoke flow was analyzed from the simulation results. The proper plan of evacuation against fire was considered through the results. The fire driven flow was simulated using FDS code in which LES method was applied. The Heat Release Rate was 10MW and the ultrafast model was applied for the growing model of the fire source. The proper mesh size was determined from the characteristic length of fire size. The parallel computational method was employed to compute the flow and heat eqn's in the meshes, which are about 10,000,000, with 6cpu of the linux clustering machine.

• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3307-3311
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• 2013

A new fiber optical sensor was developed for the determination of 2,4-dichlorophenol (DCP). The sensor was based on DCP oxidation by oxygen with the catalysis of iron(III) tetrasulfophthalocyanine (Fe(III)PcTs). The optical oxygen sensing film with $Ru(bpy)_3Cl_2$ as the fluorescence indicator was used to determine the consumption of oxygen in solution. A lock-in amplifier was used for detecting the lifetime of the oxygen sensing film by measuring the phase delay change of the sensor head. The different variables affecting the sensor performance were evaluated and optimized. Under the optimal conditions (i.e. pH 6.0, $25^{\circ}C$, Fe(III)PcTs concentration of 0.62 mg/mL), the linear detection range and response time of the sensor are $1.0{\times}10^{-6}-9.0{\times}10^{-6}$ mol/L and 250 s, respectively. The sensor displays high selectivity, good repeatability and stability, and can be used as an effective tool in analyzing DCP concentration in practical samples.

• Journal of Ginseng Research
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• v.40 no.1
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• pp.62-67
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• 2016

Background: Ginseng, which is widely used in functional foods and as an herbal medicine, has been reported to reduce the proliferation of prostate cancer cells by mechanisms that are not yet fully understood. Methods: This study was designed to investigate the changes in ginsenoside content in ginseng after treatment with a microwave-irradiation thermal process and to verify the anticancer effects of the extracts. To confirm the anticancer effect of microwave-irradiated processed ginseng (MG), it was tested in three human prostate cancer cell lines (DU145, LNCaP, and PC-3 cells). Involvements of apoptosis and autophagy were assessed using Western blotting. Results: After microwave treatment, the content of ginsenosides Rg1, Re, Rb1, Rc, Rb2, and Rd in the extracts decreased, whereas the content of ginsenosides 20(S)-Rg3, 20(R)-Rg3, Rk1, and Rg5 increased. Antiproliferation results for the human cancer cell lines treated with ginseng extracts indicate that PC-3 cells treated with MG showed the highest activity with an half maximal inhibitory concentration of $48{\mu}g/mL$. We also showed that MG suppresses the growth of human prostate cancer cell xenografts in athymic nude mice as an in vivo model. This growth suppression by MG is associated with the inductions of cell death and autophagy. Conclusion: Therefore, heat processing by microwave irradiation is a useful method to enhance the anticancer effect of ginseng by increasing the content of ginsenosides Rg3, Rg5, and Rk1.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.39 no.5
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• pp.535-543
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• 2002

In this paper, we propose a new gaze detection method using 2-D facial images captured by a camera on top of the monitor. We consider only the facial rotation and translation and not the eyes' movements. The proposed method computes the gaze point caused by the facial rotation and the amount of the facial translation respectively, and by combining these two the final gaze point on a monitor screen can be obtained. We detected the gaze point caused by the facial rotation by using a neural network(a multi-layered perceptron) whose inputs are the 2-D geometric changes of the facial features' points and estimated the amount of the facial translation by image processing algorithms in real time. Experimental results show that the gaze point detection accuracy between the computed positions and the real ones is about 2.11 inches in RMS error when the distance between the user and a 19-inch monitor is about 50~70cm. The processing time is about 0.7 second with a Pentium PC(233MHz) and 320${\times}$240 pixel-size images.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.6
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• pp.1462-1468
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• 2014

Xe gas is moved to target from GPM. It is used to feasible nuclear reaction from proton of 30MeV cyclotron being investigated by the Xe-124 gas target system. This system is divided into four parts. The hardware system was constructed by solidworks 3-D CAD and Helium supply is to cool the Havor foil. The Cooling water has the job of cooling down the temperature when Xe gas is being investigated in the target. Temperature and pressure gauges are attached to be checked easily. GPM has the part that prepares to transport Xe gas. There are storage vessel that stores Xe gas, the cold trap that filters humidity and impurity and lastly storage vessel that temporarily stores Xe gas. HCS using the helium is to clean and cool for each part. These parts are configured with SIEMENS PLC and PcVue monitoring program for more comfortable and easy maintenance.

• The Journal of Dong Guk Oriental Medicine
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• v.8 no.1
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• pp.171-190
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• 1999

This following is effect of Buthus martensi Karsch(BMK) extract on dextran-thrombus model, KCN-induced coma, cytotoxicity of brain etc. BMK extract significantly increased number of platelet and fibrogen and significantly shortened the prothrombin time as compared with control group treated with dextran. BMK extract didn't affect the changes of hematocrit as compared with control group treated with dextran. BMK extract induced a significant inhibition of human platelet aggregation induced by thrombin and ADP but did not affect human platelet aggregation induced by collagen. BMK extract showed a protective effect on pulmonary thrombosis induced by collagen and epinephrine. BMK extract prolonged the duration of KCN-induced coma and showed a protective effect on cytotoxicity of PC12 cells induced by amyloid ${\beta}$ protein(25-35) in a dose dependent manner. These results suggested that BMK extract might be usefully applied for prevention and treatment of thrombosis and brain damage.