• Journal of the Korean Society of Food Science and Nutrition
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• v.30 no.6
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• pp.1260-1265
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• 2001

This study was performed to investigate the protective effects of Hovenia dulcis Thunb on hepatotoxicity in carbon tetrachloride-intoxicated rats. Male Sprague-Dawley rats (220~240 g) were used as experimental groups, which were divided into 7 groups; Control group, $CCl_4$-treated group, hexane fraction pretreated and $CCl_4$-treated group, chloroform fraction pretreated and $CCl_4$-treated group, ethylacetate fraction pretreated and $CCl_4$-treated group, butanol fraction pretreated and $CCl_4$-treated group, $H_2O$ fraction pretreated and $CCl_4$-treated group. After 6 days, the activities of aminotransferase, contents of cholesterol, TG and hepatic lipid peroxide content in chloroform fraction pretreated and $CCl_4$-treated group were significantly decreased (p<0.05) compared to the only $CCl_4$-treated group. The content of glutathione and activities of GST in chloroform fraction pretreated and $CCl_4$-treated group were also significantly increased (p<0.05) compared to the only $CCl_4$-treated group. In addition, activities of SOD, catalase and GSH-Px in chloroform fraction pretreated and $CCl_4$-treated group were significantly decreased (p<0.05) compared to the only $CCl_4$-treated group. These results indicated that the chloroform fraction of Hovenia dulcis Thunb methanol extract showed hepatoprotective effect in carbon tetrachloride-intoxicated rats.

• Journal of the Korean Ceramic Society
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• v.40 no.4
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• pp.323-327
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• 2003

Microwave dielectric properties of (P $b_{0.4}$C $a_{0.6}$)[($Fe_{\frac{1}{2}}$N $b_{\frac{1}{2}}$)$_{1-x}$ (M $g_{1}$ 3/N $b_{2}$ 3/)x] $O_3$ (PCFMN) ceramics were investigated as a function of (M $g_{1}$ 3/N $b_{2}$ 3/)$^{4+}$ content (0.1$\leq$x$\leq$0.8). A single perovskite phase with the cubic structure was obtained through the given composition range. The unit cell volume was increased with (M $g_{1}$ 3/N $b_{2}$ 3/)$^{4+}$, due to the larger average ionic size of (M $g_{1}$ 3/N $b_{2}$ 3/)$^{4+}$ than that of ($Fe_{\frac{1}{2}}$N $b_{\frac{1}{2}}$)$^{4+}$ for B-site ion. Dielectric constant (K) and Temperature Coefficient of Resonant Frequency(TCF) of PCFMN ceramics were dependent on (M $g_{1}$ 3/N $b_{2}$ 3/)$^{4+}$ content due to the decrease of ionic polarizability and B-site bond valence, respectively. Qf value was decreased with (M $g_{1}$ 3/N $b_{2}$ 3/)$^{4+}$ content due to the decrease of grain size. Typically, K of 73.56, Qf of 5,074 GHz and TCF of -6.45 ppm/$^{\circ}C$ were obtained for the specimens with x=0.4 sintered at 125$0^{\circ}C$ for 3 h.125$0^{\circ}C$ for 3 h.

• Economic and Environmental Geology
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• v.43 no.5
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• pp.477-490
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• 2010

The Gagok stratabound skarn deposit is the result of the intrusion of the Cretaceous granitic pluton into the Paleozoic calcareous rocks. The subvolcanic intrusion ranges in composition from quartz monzonite to granite porphyry with I-type, calc-alkaline and weakly peraluminous characteristics. Both endoskarn and exoskarn are developed at the Gagok Zn-(Pb) deposit, with more exoskarn than endoskarn. Geochemical and mineralogical characteristics in the Seongok and Wolgok orebodies can be treated in terms of self-organization. Sphalerites in the Gagok ore can also incorporate minor amounts of Mn, Cd, Cu and In. Trace element concentrations in different orebodies vary because fractionation of a given element into sphalerite is influenced by formation temperature and the amount of sphalerite in the ore. A group of high In/Zn and Cd/Zn ratios in ores, and low Mn/Fe ratios in sphalerites are correlated with proximal processes of a magmatic source. The pattern of minor/trace element variations in ores and sphalcrites can be used for petrogenetic interprctation, e.g., orebody zonation related to crystallization temperature and fluid d sources.

• Korean Journal of Ecology and Environment
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• v.40 no.2
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• pp.264-272
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• 2007

Runoff of non-point pollutants has affected bad influence to water quality of river as reaching within short time. For this reason, reducing them prior to reaching aquatic systems or treating them after collection from discharge process of pollutants are desirable for efficient treatment of pollutants. This study was carried out to develop an ecotechnological method to prevent further aggravation of water quality by non-point source through vegetation filter strips. This study has placed a focus on improving infiltration capacity of soil for the optimum condition of vegetation filter strips. Therefore, we used titled soil filter strips instead of vegetation filter strips in this study. The three types of soil tilter strips were used in a bench scale experiment before applying to the field. The reduction efficiency of pollutants in soil filter strips (SS $84.5{\sim}92.5%$, BOD $67.9{\sim}80.6%$, T-N $43.4{\sim}76.6%$, T-P $40.6{\sim}87.4%$, Cu $28.3{\sim}48.1%$ Fe $92.1{\sim}97.7%$, Pb $81.4{\sim}97.3%$) was much higher than that of the controled group. And non-point pollutants reduction efficiency by soil filter strip's forms was estimated to be distinguishing in order of bio material, mixture of sand and gravel and lastly the whole gravel. In the event, the whole reduction efficiency of pollutants on the soil filter strips disclosed good results.

• Water for future
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• v.16 no.4
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• pp.245-252
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• 1983

Recently river water pollution in Korea is given rise to serious problem in aspect of crop production, drinking well, water contamination and etc. Under these urgent situations, it is prime importance to protect water resources from pollutants. An environmental isotope survey of the groundwater form the shallow alluvial and the underlying crystalline rock aquifer of the Han River Basin has been undertaken, Analysis of the data has I) confirmed the hypothesis that the groundwater from the metropolitan area is recharged from the river whereas that form the non-urbanized region of the Basin is replenished by the infiltrating precipitation; ii) shown that crystalline rock aquifers are recharged by the ground water form the overlying alluvium. Old groundwater is a group of wells with tritium values in the range of 0 to 2 TU. These low values indicate that the water sampled was recharged much ealier, at least a few decades, than the other groundwater samples of higher tritium content. The low values in this region may, in fact, reflect the effect of the impermeable clay layers which impede infilteration from the surface. Stable isotope evidence confirmed that a recharge in the karst area occurs at a significantly greater elevation than that to the alluvial aquifer. An analysis of the tritium level collected over an annual cycle suggests that the residence time of groundwater is probably not more than a few months. There does not appear to be any correlation between the trace level of Zn, Mn and Pb in the groundwater and the mechanism of the recharge.

• Journal of the Microelectronics and Packaging Society
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• v.22 no.2
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• pp.47-53
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• 2015

The effects of electroless nickel immersion gold (ENIG) and organic solderability preservative (OSP) surface finishes on the in-situ intermetallics reaction and the electromigration (EM) reliability of Sn-3.0Ag-0.5Cu (SAC305) solder bump were systematically investigated. After as-bonded, $(Cu,Ni)_6Sn_5$ intermetallic compound (IMC) was formed at the interface of the ENIG surface finish at solder top side, while at the OSP surface finish at solder bottom side,$ Cu_6Sn_5$ and $Cu_3Sn$ IMCs were formed. Mean time to failure on SAC305 solder bump at $130^{\circ}C$ with a current density of $5.0{\times}10^3A/cm^2$ was 78.7 hrs. EM open failure was observed at bottom OSP surface finish by fast consumption of Cu atoms when electrons flow from bottom Cu substrate to solder. In-situ scanning electron microscope analysis showed that IMC growth rate of ENIG surface finish was much lower than that of the OSP surface finish. Therefore, EM reliability of ENIG surface finish was higher than that of OSP surface finish due to its superior barrier stability to IMC reaction.

• Science of Emotion and Sensibility
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• v.26 no.3
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• pp.69-82
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• 2023

High-tech sensibility textile and fashion, in which consumers' emotions and various textile and fashion technologies are converged, is an important industrial group. It is important to develop the ability to apply in practice by gathering the creative by understanding other fields and exchanging ideas through interdisciplinary collaboration in the field of emotional engineering. Through interdisciplinary research and collaboration, talent must be nurtured of individuals who would lead the era of the 4^th Industrial Revolution with the ability to empathize with others as well as the creative convergence-type intellectual ability necessary for the rapidly changing society. To determine content-creation methods, basic research is conducted. Additionally, this study investigates on the current status and educational process of the emotional textile-fashion industry worldwide. To nurture talents in the textile and fashion sensibility science, the basic contents are created to manage the knowledge that delivers sensibility science and the ICT related to this field, as well as in the intensive, PB-style conceptual design based on sensibility. The process from derivation of consumer emotion analysis and product development can be experienced through smart kit practice. Moreover, various methods are developed to set up intellectual property rights generated while developing ICT convergence products as start-ups. The study also covers new knowledge rights to develop emotional textile fashion.

• The Journal of the Petrological Society of Korea
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• v.14 no.2 s.40
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• pp.83-92
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• 2005

It has recently been proposed that granites can be divided into hot and cold ones by absence and presence of inherited zircon, respectively, which is closely related to zircon saturation temperature. The Phanerozoic granites in South Korea are divided into high- and low-Zr groups in a $SiO_2-Zr$ diagram, which appears to be related to their intrusive age. Most Triassic-Jurassic granites belong to low-Zr group, whereas most Cretaceous-Early Tertiary granites belong to the high-Zr group with the exception of geographically distinct Masan and Jinhae granites that belong low-Zr group. Calculated zircon saturation temperatures using major elements and Zr contents indicate that the Cretaceous-Early Tertiary granites $(608-834^{\circ}C,\;average\; 782\pm31^{\circ}C)$ except for the Masan and Jinhae granites $(average\;759\pm16^{\circ}C)$ show higher temperature than the Triassic-Jurassic granites $(642-824^{\circ}C,\;average\;756\pm31^{\circ}C)$. U-Pb zircon isotope data of the Triassic-Jurassic granites reported so far define discordia in a concordia diagram, which indicates presence of inherited zircon and agrees with their low zircon saturation temperatures. So the Triassic-Jurassic granites appear to belong to cold granite. On the other hand, presence or absence of inherited zircon has not been known for the Cretaceous-Early Tertiary granites with relatively high zircon saturation temperature, so that their classification into hot or cold granite awaits further study. Nevertheless, the Creatceous-Early Tertiary granites may have formed at higher temperature than the Triassic-Jurassic granites, since zircon saturation temperature reflects formation temperature of magma to a certain degree.

• Journal of Food Hygiene and Safety
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• v.16 no.3
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• pp.212-220
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• 2001

To investigate the modifying effect of Kwao Kreu, Pueraria mirifica (PM), we performed two kind of studies which are the non-surgical medium-term carcinogenicity study and the modulation of gap junctional intercellular communication study. The first study, a non-surgical medium-term carcinogenicity bioassay was done to investigate the modifying effect of Kwao Keru, Pueyaria mirifca (PH), a rejuvenating folk medicine from Thailand, on the male F344 rat liver. Specific pathogen free, male 6-week-old F3444 rats were divided into ten groups. To induce hepatocarcinogenesis, those in all groups were given a single i.p. injection of DEN (200 mg/kg) and were received two i.p. injection of DGA (300 mg/kg) at the ends of weeks 2 and 5. Rats of group 3-6 were given sodium phenobarbital (PB 0.05% in drink). A diet containing 10 mg/kg PM was given to group 2 during the post-initiation phase and to groups 4 and 5 during promotion and initiation phase, respectively. Group 6 was given the experimental diet alone throughout the experiment (8 weeks). Rats of group 7, 8, 9 and 10 were fed 1000 mg/kg PH in the same manner as group 2, 4, 5 and 6. All animals were sacrificed at 8 weeks after DEN administration. Result of the immunohistochemical staining of the glutathione S-transferase placental form (GST-p) indicated that the numbers and areas of the preneoplastic leisions were not significantly changed in all PM treatment group comparing to control group. Also the numbers and areas of GST-p positive foci among group 7, 8, 9 and 10 were not significantly changed in comparing to control group. To study the effect of PM on the modulation of gap junctional intercellular communication, the present study was performed scrape-loading dye transfer (SL/DT) assay in human keratinocytes. The results showed that PM could not modulate GJIC. These results indicate that Pueraria mirifica may have no carcinogenic effects on experimental hepatocarcinogenesis in rats and gap junctional intercellular communication in human keratinocyte.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.3
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• pp.342-350
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• 2005

In the present work antidotal effect of dietary garlic was studied on lead-intoxicated rat. One of 5 groups of young Wistar sp. male rat, aged 4 weeks for control were fed only normal diet. Lead (25 ㎎/㎏.bw/week) was administered to other four groups for plumbism model over 4 weeks, of which three groups were supplemented with one of the following raw garlic juice: 1.10 (1% diet), 2.21 (2%) and 3.31 (3%) ㎎/㎏.bw/day respectively. Body weight gain rates in all garlic group significantly increased, especially in 2% garlic group that showed 9.8% net gain, as compared with only-lead treated group but lower values than control. The fecal and urinary lead excretion in all garlic groups significantly increased in a dose dependent fashion with highest value of 9.59% net gain in 3% garlic group as compared to lead treated control group. In comparison with lead treated control group, all garlic groups showed significantly increased hemoglobin contents, hematocrit values (Hct), red blood cell (RBC) count, mean corpuscular volume (MCV), and δ-amino levulinic acid dehydratase (δ-ALAD) activities. The values of 2% and 3% garlic groups remarkably increased while no significant difference between the values of 2% and 3% garlic groups was observed. The ALT activities, blood urea nitrogen (BUN) and creatinine (CR) in all garlic groups significantly decreased as compared with lead-treated control group. The values of 2% garlic group were the lowest and significantly different from the values of 1% and 3% garlic groups. The results showed that 2%-3% garlic juice in diet had obviously antidotal effects in lead-poisoned rats by promoting lead excretion. However, mega dose garlic such as in 3% garlic group might have some adverse effects on hepatic and renal functions in rats. In conclusion, the dietary habit to take ordinary garlic sauce in appropriate amount, may be helpful for preventing lead or other heavy metal intoxication.