• Korean Journal of Radiology
• /
• v.22 no.9
• /
• pp.1462-1474
• /
• 2021

There are various diseases of the gallbladder and cystic duct, and imaging diagnosis is challenging for the rare among them. However, some rare diseases show characteristic imaging findings or patient history; therefore, familiarity with the imaging presentation of rare diseases may improve diagnostic accuracy and patient management. The purpose of this article is to describe the imaging findings of rare diseases of the gallbladder and cystic duct and identify their pathological correlations with these diseases.

• Korean Journal of Veterinary Research
• /
• v.24 no.2
• /
• pp.173-181
• /
• 1984

This paper dealt with the histopathological observations of the perirenal edema in pigs and rabbits administered with Amaranthus retroflexus, based on the clinical and pathological observations of the porcine perirenal edema naturally occurred in Korea. The results observed are summarized as follows; In the natural case, clinical signs were trembling, weakness and incoordination of the hindquarters, followed by sternal recumbency, coma and death. Death usually occurred within 24 hours after the signs of illness appeared. In gross findings, the grayish yellow fluid in the perirenal area was observed in each case. In some cases, the amount of fluid in the thoracic and abdominal cavities was increased and the yellowish red color of the hydrothorax and ascites was seen. When the renal capsule was incised, the kidneys were enlarged and congested and petechiae on the cortical surface and blood clots on the capsule appeared. In microscopical findings, there were cloudy swelling, hyaline droplets and necrosis of the convoluted tubules containing proteinaceous casts and a few oxalate crystals. In addition, interstitial and perivascular edema, distention of the Bowman's space and the convluted tubules and hemorrhages were recognized. In the weanling pigs and the adult pig fed various weeds, including Amaranthus retroflexus, Euxolus blitum and Portulaca oleracea, the pigs fed Amaranthus retroflexus appeared clinical signs and pathological findings of perirenal edema usually seen in the pigs of natural cases. In the pigs fed Euxolus blitum or fed Portulaca oleracea, neither clinical signs nor pathological changes were seen. It was regarded that this disease was affected with Amaranthus retroflexus, but there was no sensitivity in the adult pigs.

• Journal of Korean Neurosurgical Society
• /
• v.64 no.4
• /
• pp.585-591
• /
• 2021

Objective : Filum transection is one of the most commonly performed operative procedure in pediatric neurosurgery. However, the clinical and pathological features as well as the surgical indication are not well-established. This study aimed to analyze the characteristics of patients who underwent transection of the filum during the last 10 years in a single institute. Methods : A total of 82 patients underwent transection of the filum during the period. As a general rule, we performed the transection in patients who are symptomatic or have abnormality in the urologic or neuromuscular evaluations. There were exceptions as asymptomatic patients who only fit the definition of thickened filum (width greater than 2.0 mm or conus level below L3 vertebral body) were operated by parent's wish or surgeon's preference according to radiological findings, etc. Results : Seventy-six out of 82 patients had fibrous tissue in the pathologic specimen of filum. Interestingly, patients who had glial cells were more correlated with no preoperative syrinx, and no progression of syrinx even for those who did have syrinx initially. Also, larger percentage of symptomatic patients had peripheral nerve twigs than asymptomatic patients. No difference in conus level or thickness of filum was found between patients with or without preoperative syrinx. Significantly more patients with syrinx (56%) were chosen to be operated without any symptom or abnormality in study i.e., solely based on radiological findings than those without syrinx (21%). The surgical outcome for syrinx was favorable, as all but one patient had either improved or static syrinx. The exceptional case had increase in size due to the upward displacement of the proximal end of the cut filum. Conclusion : This study evaluated the pathological, clinical, radiological features of patients who underwent transection of the filum. Interesting correlations between pathological findings and clinical features were found. Excellent outcome regarding preoperative syrinx was also shown.

• Korean Journal of Veterinary Research
• /
• v.27 no.2
• /
• pp.269-275
• /
• 1987

Radiation-induced life shortening, carcinogenesis and other pathological changes were investigated in NIH(GP) mice after $^{60}Co-{\gamma}$ ray irradiation(100~700rads). The results were summarized as follows: 1. There were little difference in body weights, hematological examination and other clinical findings between normal and irradiated groups. 2. Mean survival time of the mice after irradiation were decreased dose-dependently. 3. Main gross findings of the mice irradiated were appeared as enlargement of spleen, thymus and lymph nodes, tumorous nodules of lung and cyst of ovary. Especially, enlargement of thymus was promineort in high dose group. 4. Microscopically, there were various findings including myeloid leukemia, thymic lymphoma, lung adenoma, adenosquamous cell carcinoma of pancreas, pneumonia and other pathological changes. Especially thymic lymphoma was highly frequent in the 700 rads group.

• Korean Journal of Poultry Science
• /
• v.30 no.1
• /
• pp.55-59
• /
• 2003

A necrotizing skeletal myopathy was diagnosed in three flocks of 30,000 thirty-eight-week-old layer breeder chickens. The mortality attributed to the myopathy was 17.7%, 12.3% and 21.1% in flock A, B and C, respectively. Clinically, chickens were showed depression, anorexia, posterior paresis, inability to rise, incoordination, reluctance to move, and leg trembling and weakness. The most striking findings at necropsy was pale streaking in the muscles of the thighs and legs. Microscopic lesions included myofiber degeneration and necrosis with massive cellular proliferation interpreted as sarcolemmal nuclei proliferation. Plasma creatine kinase, asparte aminotransferase and akaline phosphatase were markedly elevated. In conclusion, author suggested that submitted chickens were affected by ionophores poisoning.

• Korean Journal of Veterinary Research
• /
• v.35 no.2
• /
• pp.369-374
• /
• 1995

Aujeszky's disease virus(ADV) was inoculated intranasally into the Korean native goats to investigate pathological findings and pathogenesis of ADV infection by using of histological and immunohistochemical methods and in situ hybridization(ISH). Clinical signs of salvation, pyrexia, pruritus and staggering were followed by death with five days after inoculation, Pathoanatomical findings were edema of the lung and the urinary bladder with hemorrhage and congestion, petechial hemorrhages on the endo-and epicardium, renal congestion, moderate splenomegaly and cystic edema. Main microsocpic lesions observed in all infected goats were confined to the CNS and charcterized by perivascular cuffing with lymphocytes and macrophages, focal gliosis, neuronal degeneration and necrosis, and intranuclear inclusion bodies in the neurons and glial cells. Positive reactions to ADV were detected more frequently in the nuclei than in the cytoplasms of infected nerve cells in the CNS by immunohistochemistry and ISH. Frequenctly localized sites of ADV in the CNS were olfactory bulb, prietal cortex, callosal sulcus and corpus callosum. Positive reactions were also detected in the tonsillar epithelium, and alveolar macrophage and sloughed epithelium of the lung.

• Journal of Embryo Transfer
• /
• v.14 no.3
• /
• pp.211-217
• /
• 1999

The objective of this study was to determine the cause and prevalence of bovine abortion and stillbirth in Kyungi-do area. Seventy three bovine fetuses were collected from farms and submitted to the College of Veterinary Medicine, Seoul National University. Submitted fetuses were evaluated during a 4-month period (July to November, 1999) for pathological lesion, tissue protozoa, bacteria and viral infection. The average proportion of abortions was decreased with parity in 73 abortion heifers and cows. Monthly incidence rate of bovine abortion was not different in this study. In fetuses from 90 to 282 days gestation, the majority were between 150 and 250 days gestation(58%). The cause of abortion or stillbirth was determined in 51% of the cases examined. In 15(21%) of the fetus, neosporosis were diagnosed by pathological findings. In three (4%) additional fetuses in three additional fetuses, suspected Neosporosis by pathological lesion, and in 3 (4%) fetuses examined Neopsorosis were diagnosed in 15 feturses and in 3 fetuses, Neosporosis was suspected by pathological legions. Neosporosis / viral infection were diagnosed in three additional fetuses). Miscellaneous bacterial infection, BVDV, iatrogenic cause, Neosporosis / IBRV / BVDV, miscellaneous viral, IBRV/BVDV and others were 3(4%), 3(4%), 2(3%), 2(3%), 1(1%), 1(%) and 9(12%) respectively. The cause and incidence of bovine abortion in different area in Kyungi-do was not different in this study.

• Journal of fish pathology
• /
• v.18 no.2
• /
• pp.105-118
• /
• 2005

Anemia in fish can be easily recognized by examining the gill color and physical properties of sampled blood. The number of erythrocytes is generally within 1-3 ${\times}10^6$. Hematocrit (Ht) reportedly ranges 35-45% in many of reports which is nearly the same as that in mammals. Anemia in fish can also be classified as hemorrhagic, hemolytic and hypoplastic ones. Fish are also expected to have similar pathological effects by anemia as in mammals. From the fact that fish can survive under extremely low hematocrit below 10% and antarctic icefish (Chanenocephalus aceratus) has no erythrocytes, different pathological effects were expected. Anemia is considered to have one of the most important health parameters, based on the pathological aspect. Therefore, by reviewing clinical and histopathological findings of most of fish diseases already known and then adding our results of experimental anemia, diseases and factors related to anemia were summarized and the pathological effects was discussed.

• Korean Journal of Social Welfare
• /
• v.54
• /
• pp.177-201
• /
• 2003

Gambling is prevailing in our society and the family problems of gamblers are also serious. In order to reduce the problems of gamblers and their families, the basic research on gambling would be the first step. In light of this, this study is a survey which has two objectives: to grasp the overall conditions of gambling and the proportion of pathological gamblers; to find the differences between the pathological gamblers' group and the general group in terms of various aspects of family relations in Choongchung area. The findings of this study is as follows, The respondents tend to gamble most with korean playing cards, either in winter or regardless of seasons. They tend to gamble most with family members, relatives, or friends. About 20% of them gamble more often than once a month, and 60% started gambling in their twenties or thirties. The proportion of pathological gamblers was found to be 11.6% of the sample of this study, with men and rural area residents to be significantly more than women and urban area residents. In the various aspects of family lives, such as marital satisfaction, family relations, family violence, family history of addiction, how to spend leisure time with family, it was found that the pathological gamblers' group has significantly more problems than the general group. On the basis of the above findings, the suggestions were made as follows. Firstly, the counter plan to gambling is necessary in the rural area, especially in winter time. secondly, positive leisure activities which substitute gambling needs to be developed, especially for men. Thirdly, family education and family therapy Program is required for the pathological gamblers and their families. Fourthly, governmental policy is necessary for the budget to prevent and treat gambling problems.

• Sleep Medicine and Psychophysiology
• /
• v.3 no.2
• /
• pp.1-17
• /
• 1996

To demonstrate the clinical usefulness of electroencephalography (EEG) and factors increasing the usefulness of EEG, the authors evaluated each relationship between EEG related factors and clinical variables, and neuroimaging studies (CT and MRI)-related factors, and factors which are related with routine neurological examination for 207 patients who had been evaluated with both of EEG and neuroimaging study(CT or/and MRI). The results were as follows: 1) Abnormality of EEG findings had significant relationships with chief complaints, diagnosis, medication use, seizure attack, pathological reflex, and level of consciousness. However there were no significant correlations between abnormality of EEG findings and neuroimaging studies (CT and MRI)- related factors. 2) Laterality of EEG findings had significant relationships with abnormality, laterality, and focality of CT findings, and also with abnormality of MRI findings. But there were no significant correlations between laterality of EEG findings and clinical variables, and neurological examination-related factors. 3) Anterior-posterior distribution of EEG findings was significantly related with medication use. 4) Focality of EEG findings had significant relationships with sex, sensory dysfunction sign, and cerebellar dysfunction sign. But there were no significant correlations between focality of EEG findings and neuroimaging studies(CT and MRI) related factors. 5) Abnormal EEG pattern had significant correlations with various factors, such as age, chief complaints, duration from onset of symptom to taking MRI, seizure attack, abnormality and nature of lesion in CT findings, cortical atrophy in MRI findings, motor dysfunction sign, sensory dysfunction sign, and pathological reflex. 6) With abnormality on sleep activation, age, age of onset, seizure attack, ventricular enlargement in CT findings, and abnormality of MRI findings were significantly correlated. 7) With abnormality on hyperventilation activation, duration of illness and laterality of MRI findings were significantly correlated. Above results may suggest that abnormality of EEG findings is more closely related with functional change of the brain than structural changes of the brain and laterality of EEG findings is vice versa. And also that medication use has an influence on anterior versus posterior distribution of EEG findings and focality of EEG findings is not related with structural changes of the brain. Activation with sleep may be effective to show age differences and provocation of seizure activity and hyperventilation may be effective to detect the abnormal EEG findings by cerebrovascular insufficiency.