• 제목/요약/키워드: pathological change

검색결과 241건 처리시간 0.027초

패션테라피 효과 유지에 대한 질적 접근 (Qualitative Approach to Maintaining the Effect of Fashion Therapy)

  • 이새은;이유리
    • 한국의류학회지
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    • 제43권3호
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    • pp.311-326
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    • 2019
  • Previous studies on the effect of fashion therapy have been conducted with psychiatric patients; however, this study explores the effects in fashion therapy for women with non-pathological problems. Previous studies did show if the effect of fashion therapy could be maintained continuously; therefore, we intend to examine the existence of the long-term effects of fashion therapy in an empirical manner and provide implications for social and public interest. This study used a qualitative approach to investigate the effects of fashion therapy with the following results. Low self-esteem, negative emotions, and rigid thinking symptoms appeared by numerous stress factors, and various changes were made through fashion therapy. Emotional changes such as positive emotions and feeling of achievement, and psychological changes including self-concept formation, change of sight and self-esteem improvement appeared. Sociological and behavioral changes were also identified. We found the maintained and long term effects of fashion therapy; therefore, study provides academic implications to reconsider the social value of fashion.

금화교역으로 본 폐계생리에 대한 소고 (A study on the physiology of Pulmonary series - according to the exchang of Metal and Fire -)

  • 손창수;김길훤
    • 동의생리병리학회지
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    • 제16권1호
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    • pp.23-31
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    • 2002
  • This research aims is to study physiolgy and pathology of lung on Suenbal-Sukkang action occuring with the exchang of Metal and Fire of nature. The exchange of Metal and Fire(金火交易) represents differience of temperature inside and outside of the atmosphere in according to Sun-heat on earth descended in passing Hazi(夏至). On the above fact, the Suenbal-Sukkang( action representing the Exchang of Metal and Fire happens in lung of body with properties of metal. too. These phenomena are physiological phenomenas of Pulmonary series(肺系). Accordingly, the action of Suenbal-Sukkang radiates heat and converge water with the properties of Autumn-Metals in change actions of nature. In order To interpret physiology action of Pulmonary energy(肺氣), I have studied Metal-glass theory(金鏡說) of Muk Za(墨子), and made a comparative study of a climatic change passing from summer to autumn in four season caused by the revolution of earth Thus, to interpret the action of Suenbal-Sukkang can be inferred by the phenomena of physiology and pathology of Pulmonary series. From the result of this study, I know that functions representing of the Suenbal-Sukkang take place in processing the exchange of Metal become phenomena in physiology of Pulmonary series(大腸, 皮膚, 鼻, …), and abnormal functions functions representing the Suenbal-Sukkang become pathological phenomenas of Pulmonary series.

Acute Oral Toxicity of Extract Derived from Fruiting Body of Phellinus gilvus in Rats

  • Bae, Jae-Sung;Jang, Kwang-Ho;Park, Sung-Guk;Jo, Woo-Sik;Rhee, Man-Hee;Kwon, Oh-Deog;Kim, Young-Hoan;Kim, Eun-Young;Park, Seung-Chun
    • Toxicological Research
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    • 제19권3호
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    • pp.211-215
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    • 2003
  • This study was carried out to investigate the acute oral toxicity of a crude extract derived from fruiting body of Phellinus gilvus (PGE) using male and female SD rats. Groups consisted of five male and female rats were treated with a single dose of the test substance intragastrically at 0, 500, 1,000, 2,000, and 5,000 mg/kgaj, respectively. Clinical signs, body weight change, and food and water consumption change were observed for 14 days after administration. No mortality or abnormal clinical signs in animals were shown during the observation period at the dose used in this study. Also there was no difference in net body weight gain, water and food consumption or gross pathological findings at terminal sacrifice among the groups of rat treated with different doses of the test substance. The results suggested that acute oral toxicity of PGE in rats is very low at the conditions employed in this study and $LD_{50}$ of PGE was estimated to be over 5,000 mg/$\textrm{m}{\ell}$ in both sexes of rats.

측두하악관절 장애 환자에서 관절원판후조직의 에스트로겐 수용체(ER)의 단백 발현 (EXPRESSION OF ESTROGEN RECEPTORS IN RETRODISCAL TISSUE OF THE TEMPOROMANDIBULAR JOINT DISORDER PATIENTS)

  • 김종윤;임재형;박광호;김형곤;허종기
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제35권6호
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    • pp.403-410
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    • 2009
  • Those composing temporomandibular joint (TMJ) complex such as the temporal bone, the disc and the mandibular condyle perform their own functions with organic relation. The retrodiscal tissue is the main area of pain induction and contributes to compositional change of synovial fluid. If displacement of the disc lasts long time, not only adaptive changes, but also destructive or degenerative changes may happen. It was reported that these changes and symptoms appear mostly to female rather than male and especially, in the case of patients suffering from TMJ disorder, a large quantity of female sex hormone is found in the joint synovium. And that may play a role in bone resorption and inflammation. Also, the frequency and the intensity of pain perception for female is reported to be much more than for male. In this study, we investigated the expression extents of estrogen receptors (ER) and progesteron receptors (PR) in retrodiscal tissue with immunohistochemistry among the patients received TMJ surgery and compared with MRI findings and surgical findings. We report the relations between the expression of ER in retrodiscal tissue and the pathological change in TMJ, such as inflammation, internal derangement and osteoarthritis.

고령사회에 있어서 생활환경의 변화와 유니버설디자인의 역할 (A study on the change of the living conditions and the role of the Universal Design in an aged society)

  • 김경태
    • 디자인학연구
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    • 제17권2호
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    • pp.231-240
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    • 2004
  • 본 연구는 고속성장주도의 근대화과정을 거치며 생성된 생활환경에 있어서의 다양한 문제와 그 해결방안에 관한 개념적 접근을 시도한 것이다. 고도정보ㆍ고령사회에 있어서 발생하는 다양한 문제의 본질을 $\ulcorner$도구를 포함한 생활환경에 있어서 사용성의 부조화$\lrcorner$ 에 있다고 보며, 아울러 $\ulcorner$사용이라는 행위를 통한 사회적 공평성의 확보$\lrcorner$ 는 생활인, 특히 고령자들에게 자신감과 즐거움을 제공하고, 커뮤니티 형성을 보다 원활하게 하여 삶의 질을 높이는데 중요한 역할을 한다고 할 수 있다. 본 연구는 일상생활에서 직면할 수 있는 다양한 사회적 병리 현상과 생활환경 문제에 대하여 디자인이라는 전문분야는 어떻게 관여하고 있으며, 특히 도구환경을 중심으로 하는 생활환경의 바람직한 재구축(커뮤니티 활성화를 통한 생활환경 변화)에 있어서 Universal Design의 역할에 관하여 고찰해 보았다.

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하지 근골격계질환 평가를 위한 삼차원 근.건모델의 임상적용 (A Clinical Application of 3D Muscle-Tendon Complex Model for the Estimation of Lowerbody Musculoskeletal Disorders)

  • 임용훈;최재일;최안렬;민경기;윤태선;박광용;문정환
    • Journal of Biosystems Engineering
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    • 제34권1호
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    • pp.57-62
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    • 2009
  • Kinematic analysis of MTC (Muscle-Tendon Complex) units is a key indicator for diagnosis of patients with musculoskeletal disorders because the contracture or shortening of musculo-tendinous units is known to produce pathological gaits. Therefore, the principal objective of this study was to assess the length change in the triceps surae prior to and after wearing an AFO (Ankle-Foot Orthoses) in patients with musculoskeletal disorders during a gait. In this study, analyses were conducted using a Muscle Tendon Complex model coupled with the trajectory data from markers attached to anatomical landmarks. As a result, the maximum length change in the triceps surae during a gait was 4.87% when a barefoot walking group and a walking group with AFO were compared. In particular, the difference in length changes between both groups in Soleus MTC units was found to be statistically significant in all gait phases. Our results revealed that MTC length in the AFO walking group was clearly increased over that of the barefoot walking group. In the future, further studies will be required in order to more adequately assess musculoskeletal disorders using many cases studies with regard to agricultural working conditions because this study deals with the kinematic analysis of musculo-tendinous units in the case of clinical experiments.

Association between Single Nucleotide Polymorphisms of Fatty Acid Synthase and Fat Deposition in the Liver of the Overfed Goose

  • Wu, Wei;Guo, Xuan;Zhang, Lei;Hu, Dan
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권9호
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    • pp.1244-1249
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    • 2014
  • Goose fatty liver is one of the most delicious and popular foods in the world, but there is no reliable genetic marker for the early selection and breeding of geese with good liver-producing potential. In our study, one hundred and twenty-four 78-day-old Landes geese bred in Shunda Landes goose breeding farm, Jiutai, Jilin, China were selected randomly. The fatty livers were sampled each week after overfeeding during a three week period. Polymerase chain reaction-single strand conformation polymorphism and DNA sequencing were used to identify single nucleotide polymorphisms (SNPs) of fatty acid synthase (FAS), which is an important enzyme involved in the synthesis of fat under both physiological and pathological conditions. Least-squares correlation was established between these SNPs and fatty liver weight, abdominal fat weight, and intestinal fat weight of the overfed Landes geese, respectively. The results showed that fatty liver weight of geese with EF and FF genotypes (amplified by primer P1) was significantly higher than that of the EE genotype (p<0.05), and liver weight of CD and DD genotypes (amplified by primer P2) was significantly higher than that of the CC genotype (p<0.05). Different genotype combinations showed different liver weights, and from highest to lowest were ABDD, DDEF, DDFF, DDEE, ABEF, ABFF, AADD, and CDEF. Further analysis of DNA sequencing showed that there were two SNPs within the 5' promoter region the FAS gene. The geese of EF and FF genotypes carried a change of T to C, and the geese of CD and DD genotypes carried a change of A to G. The changes of the bases could potentially influence the binding of some transcription factors to this region as to regulate FAS gene. To our knowledge, this is the first report of SNPs found within the 5' promoter region of the Landes goose FAS gene, and our data will provide an insight for early selection of geese for liver production.

다발성 관절염 실험동물 모델에서 저출력 GaAsAl 레이저 자극에 의한 소염효과 (The anti-inflammatory effect of low power GaAsAl laser stimulation on the polyarthritis of rats)

  • 장문경;심규리;최영덕
    • 대한물리치료과학회지
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    • 제9권2호
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    • pp.99-109
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    • 2002
  • We designed the experiments to elucidate the anti-inflammatory effect of low power laser stimulation on acupoint or non-acupoint using arthrogenic solution induced poly arthritis animal model. In order to achieve the experimental purpose, change in body weight paw edema, pathological changes in inflammed pint and the serum interlukin-6 level were measured after arthritis induction in acupoint later stimulated group, non acupoint laser stimulated group and non treated control animal. The results were summerized as follows: 1. The consistent increase in body weight was observed in the normal animal during whole experimental period, while the induction of arthritis significantly suppressed increase in body weight from the 15 day after arthritis induction. Especially, non treated animal group showed more suppressive effect on increase in body weight as compared to that of low power laser stimulated groups (P<0.05). 2. Low power laser stimulation on acupoint (Zusanli) significantly inhibited edema in the left side paw from the 12th day after arthritis induction as compared to that of non treated animals. This suppressive effect on paw edema was maintained until the end of experiment. 3. Laser treatment on acupoint dramatically suppressed the radiological change (i.e. new bone proliferation and soft tissue swelling) caused by arthritis as compared to that of non treated group animals. 4. Low power laser treatment reduced the increase in serum interlukin-6 caused by arthritis induction to levels observed in the normal animals. In conclusion, the results of the present study demonstrated that low power laser stimulation on acupoint has potent anti-inflammatory effect on arthritis. Thus it is recommended that low power laser be used for long term treatment of arthritis induced inflammation. However, further study is necessary to clarify the possible side effect of laser treatment depending upon intensity and duration of stimulation.

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혈부축어탕이 교원효소로 유발된 흰쥐의 뇌출혈에 미치는 영향 (Effects of Hyulboochucke-tang on the Collagenase-Induced Intracerebral Hemorrhage in Rats)

  • 김용;서일복;김순중
    • 한방재활의학과학회지
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    • 제26권1호
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    • pp.1-11
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    • 2016
  • Objectives The purpose of this study was to investigate the effect of Hyulboochucke-tang on the collagenase induced intracerebral hemorrhage in white rats. Methods To identify the effect of the Hyulboochucke-tang on intracerebral hemorrhage, intracerebral hemorrhage was induced in the right caudate nuclei of white rats. For normal group (n=12) and comparative group (n=12), saline was dosed, and vaccum evaporated Hyulboochucke-tang extract was dosed to treatment group (n=12), 3 and 10 days after the collagenase injection, the body weight, the brain weight, the size of hematoma, the size of the area of malacia, the number of apoptotic cell and the change in pathological histology were observed. Results 3 days after the injection, the brain weight(g) was considerably decreased in treatment group (n=12) compared to comparative group (n=12). The brain weight after 10 days of the injection was also considerably decreased in treatment group (n=6) against comparative group (n=6). The cross section(mm) of cerebral malacia after 10 days of the injection was considerably decreased in treatment group (n=6) compared to comparative group (n=6). The number of apoptotic cell in normal intracerebral around the area of malacia did not show considerable change between treatment group and comparative group. 12 days after the injection, the multiplication of gitter cells, astrocyte and newly formed capillaries around the area of malacia was distinct. Conclusions On the basis of these results, We sugggest that Hyulboochucke-tang controls swelling caused by hemorrhage and contributes to absorption of hematoma by multiplication of newly formed capillaries and recovery of damaged cerebral tissue by multiplication of gitter cells and astrocyte.

간섭전류 자극 방법에 따른 말초혈류의 변화 (The change of the peripheral blood circulation by the method of interferential current stimulation)

  • 박영한;황경옥
    • 대한물리치료과학회지
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    • 제18권3호
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    • pp.87-92
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    • 2011
  • Purpose : The purpose of this study is to have examined the influence on the blood circulation by comparing the differences between stimulating the sympathetic ganglion and the muscle group among the stimulation variables in interferential current stimulation and to have found out the most effective stimulating mode for the improvement the peripheral blood circulation in the interferential current stimulation. Method : The subjects of the study is the men and women in the twenties, who are in great condition and have no pathological report for the blood circulation influence. The intensity of the inferential current stimulation is the medium degree, 100 bps constant current, which is the comfort and overt degree to confirm the muscle contraction. The areas stimulated by the interferential current stimulation are the stellate ganglion area in the seventh cervical vertebrae and the forearm muscle area. The stimulating time is twenty minutes long. After stimulating the two areas, the change of the blood circulation has been measured. Results : Both stimulating the sympathetic ganglion and stimulating the muscle, before and after interferential current stimulation, we have seen that the amount of blood circulation was increased significantly and statistically in both two groups(p<.01) and that the amount of blood circulation was increased significantly and statistically in the case of stimulating the sympathetic ganglion(p<.01). Conclusion : The conclusion we received that inferential current stimulation had the clear influence on increasing the peripheral blood circulation. And stimulating the sympathetic ganglion area is more effective than stimulating muscle area directly.

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