• Mass Spectrometry Letters
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• v.6 no.4
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• pp.85-90
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• 2015

This article reviews recent analytical techniques using inductively coupled plasma-mass spectrometry (ICP-MS) immunoassay for clinical and bio analysis. We classified the techniques into two categories, direct and indirect analysis, which depend upon a guideline of whether tagging materials are used or not. Direct analysis is well known, and generally used in conjunction with various other techniques, such as laser ablation, chromatographic separations, etc. Recently, indirect analysis using tagging elements has intensively been discussed because of its importance in future applications to bio and clinical analysis, including environmental and food industries. The method has shown advantages of multiplex detection, excellent sensitivity, and short analysis time owing to signal amplification and magnetic separation. Now, it expands the application field from small biomolecules to large cells.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2005.11a
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• pp.422-425
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• 2005

In an transversely isotropic composite laminates, the velocities, the particle directions and the amplitudes of reflected and transmitted waves were obtained using the equation of motion, the constitutive equation, and the displacement equation expressed by wave number and frequency Eigenvalue problem involving a velocity was solved by Snell's law. Finally, the results were confirmed by T300 Carbon fiber/5208 Epoxy materials. This approach could be applied to the detection of flaws in a transversely isotropic composite laminates by the water immersion C-scan procedure.

• Journal of the Korean Society for Railway
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• v.8 no.5
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• pp.419-424
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• 2005

This paper has performed fatigue and nondestructive test of bogie frame for Korean tilting train. Before the fatigue test, static tests were carried out. From the test, the structural safety was investigated using Goodman diagram. After the static test, the fatigue test were conducted under tilting load conditions. The fatigue test was conducted for $10{\times}10^6$ cycles. During the fatigue test, the nondestructive tests using magnetic particle and liquid penetrant were performed at $6{\times}10^6$ cycle and $10{\times}10^6$cycle. From the crack detection tests, it was known that there was no fatigue crack in the bogie frame.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.2 s.245
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• pp.210-218
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• 2006

This paper has performed static, fatigue and nondestructive test of tilting' bolster frame for Korean tilting train. From the static test, the structural safety was investigated using Goodman diagram. After the static test, the fatigue test were conducted under tilting load conditions. The fatigue test was conducted for $10\times10^6$ cycles. During the fatigue test, the nondestructive tests using magnetic particle and liquid penetrant were performed at $6\times10^6$cycle and $10\times10^6$cycle. From the crack detection tests, it was known that there was no fatigue crack in the tilting bolster.

• Journal of Computing Science and Engineering
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• v.8 no.2
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• pp.87-93
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• 2014

Coronary artery disease (CAD) is currently a prevalent disease from which many people suffer. Early detection and treatment could reduce the risk of heart attack. Currently, the golden standard for the diagnosis of CAD is angiography, which is an invasive procedure. In this article, we propose an algorithm that uses data mining techniques, a fuzzy expert system, and the imperialist competitive algorithm (ICA), to make CAD diagnosis by a non-invasive procedure. The ICA is used to adjust the fuzzy membership functions. The proposed method has been evaluated with the Cleveland and Hungarian datasets. The advantage of this method, compared with others, is the interpretability. The accuracy of the proposed method is 94.92% by 11 rules, and the average length of 4. To compare the colonial competitive algorithm with other metaheuristic algorithms, the proposed method has been implemented with the particle swarm optimization (PSO) algorithm. The results indicate that the colonial competition algorithm is more efficient than the PSO algorithm.

• Korean Journal Plant Pathology
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• v.10 no.2
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• pp.136-139
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• 1994

Turnip mosaic virus (TuMV) was isolated from Rorippa islandica showing mild mosaic symptom in growing field of Chinese cabbage and radish. Identification of the virus was based on host range, transmission by aphids, electron micrograph, serological reaction and hybridization detection. The virus systemically infected on Chenopodium quinoa, Nicotiana clevelandii, N. glutinosa, Brassica rapa, B. campestris subsp. pekinensis and Raphanus sativus, whereas showed local infection on C. amaranticolor, Gomphrena globosa and Tetragonia tetragonoides. The virus was transmitted by aphid (Myzus persicae). The virus particle was filamentous with 720$\times$12 nm in length, and reacted positively with an antiserum of TuMV in agar gel double duffusion test. In slot-blot hybridization using the digoxigenin(DIG)-labeled RNA probe, TuMV-RNA could be detected in sap of R. islandica infected with the virus. This is the first report of a natural infection of that virus on R. islandica.

• Mass Spectrometry Letters
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• v.7 no.3
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• pp.64-68
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• 2016

Scanning electron microscopy combined with thermal ionization mass spectrometry (SEM-TIMS) was used to determine the precise isotope ratios of ultra-trace levels of uranium contained in individual microparticles. An advanced multiple ion counter system consisting of three secondary ion multipliers and two compact discrete dynodes was used for complete simultaneous ion detection. For verification purposes, using TIMS with complete simultaneous measurement, isotopes were analyzed in 5 pg of uranium of a certified reference material. A microprobe in the SEM was used to transfer individual particles from a NUSIMEP-7 sample to TIMS filaments, which were then subjected to SEM-TIMS and complete simultaneous measurement. The excellent agreement in the resulting uranium isotope ratios with the certified NUSIMEP-7 values shows the validity of SEM-TIMS with complete simultaneous measurement for the analysis of uranium isotopes in individual particles. Further experimental study required for investigation of simultaneous measurement using the advanced multiple ion counter system is presented.

• Proceedings of the KIEE Conference
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• 2000.11c
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• pp.516-518
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• 2000

정상 상태의 gas-insulated switchgear (CIS) 내부에서 발생한 부분방전 신호를 검출 할 수 있는 UHF 부분방전 검출 센서를 실험용 362 kV GIS에 적용하였다. GIS 내부에 알루미늄 이물질을 투입한 다음 120 - 180 kVrms 전압을 단계적으로 인가하고 장시간 인가전압 위상에 대한 UHF 부분방전 신호를 측정하였다. 인가전압을 높일수록 검출된 방전신호의 간격이 늘어났으며, 이물질로 사용한 알루미늄선의 길이가 길어질수록 이물질의 상승고도는 증가하였다. GIS 내부에서 이물질의 운동에 대한 간단한 계산에서도 비슷한 경향을 보임을 확인하였다.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.6
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• pp.521-525
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• 2014

Circulating tumor cells (CTCs) in the bloodstream of cancer patients provide an accessible source for detection, characterization, and monitoring of nonhematological cancers. The effectiveness of the CTC-Chip for the isolation of ovarian cancer cells was demonstrated by adapting the herringbone-chip (HB-Chip). The motions of the particles on the HB chip were simulated by a unique combination of buoyant, gravitational forces, and helical flows with a computational modeling. The motions of cells are demonstrated by applying polystylene bead and ovarian cancer cells into the microfabricated HB-Chip. The experimental results from beads and cells are well accordance with the simulated ones, as previously reported by Toner group. Thus, I expect that these modeling and experimental skills will play key roles in the clinical applications on CTC isolation as well as the basic research on characterization of CTCs under flow.

• Korean Journal of Veterinary Research
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• v.37 no.1
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• pp.155-159
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• 1997

Torovirus-like particles이 심급성의 설사로 폐사한 송아지의 분변으로 부터 검출되었다. 설사로 폐사한 송아지는 2주령으로 설사증상을 보인 5두중 2두였으며 심한 설사증상을 보인지 24시간만에 급성폐사를 나타내었다. 나머지 3두도 심한 설사증상을 보였으나 항생제 및 수액요법으로 치료를 한 후 회복되었다. 전자현미경으로 관찰된 바아러스 입자는 Woode et al이 관찰한 Torovirus 입자와 동일하였으며 그 크기는 원형입자일 경우 70~90nm의 크기로 8~10nm의 Peplomer를 가지고 있었다. 그러나 바이러스이 입자형태는 소, 돼지 그리고 사람에서 보고된 Torovirus와 마찬가지로 다양하였으며 Tube 형태로 된 것은 길이가 약 150nm에 달하기도 했다. 이 보고는 국내에서의 송아지 Torovirus 감염증의 첫 보고이며 국내에서도 Torovirus가 존재한다는 것을 입증한 것이다.