• 대한수의학회지
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• 제1권1호
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• pp.30-35
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• 1961

각종백혈구(各種白血球) 백분비계산방법(百分比計算方法)에는 거이 백종(百種)에 가까울 정도(程度)인데 학자(學者)에 따라서 각각상이(各各相異)하여 각각상이(各各相異)한 백분비(百分比)가 산정(算定)되어 어느방법(方法)을 택(擇)하여야 할것인가 곤란(困難)하다. 여기에서 가장 널리 사용(使用)하고 있는 5종방법(種方法)과 필자(筆者)가 고안(考案)한 13종방법(種方法)을 적용(適用)하여 각혈액도말표본(各血液塗抹標本)에 있는 백혈구(白血球) 실측수(實測數)와 비교검토(比較檢討)한 결과(結果) 도말표본장축(塗抹標本長軸)의 중안선부(中央線部)와 이 중안선부(中央線部)의 양변연(兩邊緣)과의 양(兩) 중안선부(中央線部) 즉(卽) 삼평행선연(三平行線緣)을 종단부(終端部)에서 초단부(初端部)까지 산정(算定)하는 방법(方法)이 비교적(比較的) 이상적(理想的) 방법(方法)이었다. 끝으로 시종강력(始終强力)히 지도편달(指導鞭撻)하여주신 김용필교수(金容珌敎授)에 심심(甚深)한 사의(謝意)를 표(表)하며 선생님(先生任)의 의도(意圖)를 백분발휘(百分發揮)치 못함에 미안(未安)한 마음 금(禁)치 못하며 선배제현(先輩諸賢)의 냉철(冷徹)한 비판(批判)과 지도편달(指導鞭撻)을 바라는바입니다.

• Molecules and Cells
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• 제24권2호
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• pp.283-287
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• 2007

$TGF-{\beta}1$ induces Ig germ-line ${\alpha}$ ($GL{\alpha}$) transcription and subsequent class switching recombination (CSR) to IgA. In the present study, we investigated the roles of two E3-ubiquitin ligases, Smurfs (HECT type) and Arkadia (RING finger type) on $TGF{\beta}1$-induced IgA CSR. We found that over-expression of Smurf1 and Smurf2 decreased $TGF{\beta}1$-induced $GL{\alpha}$ promoter activity and strengthened the inhibitory effect of Smad7 on the promoter activity. Further, over-expression of Smurf1 and Smurf2 decreased both Smad3/4-mediated and Runx3-mediated $GL{\alpha}$ promoter activities, suggesting that the Smurfs can down-regulate the major $TGF-{\beta}1$ signaling pathway and decrease $GL{\alpha}$ gene expression. In parallel, the over-expressed Smurf1 decreased the expression of endogenous IgA CSR-predictive transcripts ($GLT_{\alpha}$, $PST_{\alpha}$, and $CT_{\alpha}$) and also $TGF{\beta}1$-induced IgA secretion. Conversely over-expression of Arkadia abolished the inhibitory effect of Smad7 on $TGF{\beta}1$-induced $GLT_{\alpha}$ expression and IgA secretion. Similar results were obtained in the presence of over-expressed Smad7 and Smurf1. These results indicate that Arkadia can amplify $TGF{\beta}1$-induced IgA CSR by degrading Smad7, which interacts with Smurf1. We conclude that Smurf and Arkadia have opposite roles in the regulation of $TGF{\beta}1$-induced IgA isotype expression.

• Journal of electromagnetic engineering and science
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• 제11권1호
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• pp.42-50
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• 2011

One of the important applications of THz time-domain spectroscopy (TDS) is the detection of explosive materials through identification of vibrational fingerprint spectra. Most recent THz spectroscopic measurements have been made using pellet samples, where disorder effects contribute to line broadening, which results in the merging of individual resonances into relatively broad absorption features. To address this issue, we used the technique of parallel plate waveguide (PPWG) THz-TDS to achieve sensitive characterization of three explosive materials: TNT, RDX, and HMX. The measurement method for PPWG THz-TDS used well-established ultrafast optoelectronic techniques to generate and detect sub-picosecond THz pulses. All materials were characterized as powder layers in 112 ${\mu}m$ gaps in metal PPWG. To illustrate the PPWG THz-TDS method, we described our measurement by comparing the vibrational spectra of the materials, TNT, RDX, and HMX, applied as thin powder layers to a PPWG, or in conventional sample cell form, where all materials were placed in Teflon sample cells. The thin layer mass was estimated to be about 700 ${\mu}g$, whereas the mass in the sample cell was ~100 mg. In a laboratory environment, the absorption coefficient of an explosive material is essentially based on the mass of the material, which is given as: ${\alpha}({\omega})=[ln(I_R({\omega})/I_S({\omega}))]m$. In this paper, we show spectra of 3 different explosives from 0.2 to 2.4 THz measured using the PPWG THz-TDS.

• Journal of Periodontal and Implant Science
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• 제26권2호
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• pp.376-395
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• 1996

The neuropeptide substance P(SP) has been recognized to modulate immune systems, with close proximity between peptidergic sensory nerve endings and immune cells. These include the macrophage and neutrophil activation, IL-2 production in T cell, augmentation of Ig synthesis, mast cell degranulation, $PGE_2$ and collagenase secretion in synoviocytes. In this study I examined SP-induced various biological activities such as antimicrobial action, cytokine production, and mast cell degranulation in the presence or absence of other inflammatory cell activators. Antimicrobial studies showed that undifferentiated HL-60 cells were not affected by SP. However, SP significantly enhanced antimicrobial action of TPA-treated or dbcAMP-treated HL-60 cells which had been differentiated into PMN or macrophage/monocyte. I could not find synergistic relationship between SP and LPS in parallel experiments of the above. SP did not induce IL-l production from murine macrophage cell line RAW264.7 whether costimulated with LPS or not. Mast cell degranulation was occured only when stimulated with high dose ($10^{-5}M$) of SP and the degree of this activation was slightly reduced by simultaneous application of $MIP-1{\alpha}$. In addition, CGRP which is known to be a common coexisting neuropeptide with SP within specific fibers did not augment the function of SP on mast cell degranulation. These results suggest that immunoregulatory activities of SP could be mediated through direct upregulation of various functions of immune cells and also upregulation of responsiveness of immune cells to other immune activators.

• 전기전자학회논문지
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• 제24권1호
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• pp.368-371
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• 2020

본 논문에서는 휴대용 UHF대역 RFID 시스템을 위한 선형 테이퍼드 슬롯 정류 안테나를 제안하였다. 제안한 정류 안테나는 별도의 유전체 기판을 사용하지 않기 때문에, 얇은 금속 두께로 평판형 안테나를 구현하였다. 정류 안테나는 입력 RF전력을 출력 DC전압으로 전환하는 정류회로는 2개의 쇼트기 다이오드를 이용한 배전압회로를 이용하였으며, 선형 테이퍼드 슬롯 안테나에 집적하여 정류 안테나를 설계하였다. 배전압 정류회로와 선형 테이퍼드 슬롯 안테나의 임피던스 공액정합을 위하여, 테이퍼드 슬롯의 각도와 안테나 급전선의 길이의 조절을 통해 source-pull 방법을 이용하였다. 제안한 안테나 시제품은 자유공간 무선환경실험 환경에서 RF-DC전환 실험과 원거리장 안테나 방사패턴 측정실험을 통해 회로 및 방사 특성을 검증하였다. 최종 제안한 안테나는 중심주파수 915 MHz 기준으로 0.23-파장(75 mm)와 0.18-파장(60 mm) 크기로 소형화하였다.

• 전기학회논문지
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• 제58권2호
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• pp.391-398
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• 2009

In this study, we introduce the design methodology of an optimized fuzzy cascade controller with the aid of hierarchical fair competition-based genetic algorithm(HFCGA) for ball & beam system. The ball & beam system consists of servo motor, beam and ball, and remains mutually connected in line in itself. The ball & beam system determines the position of ball through the control of a servo motor. The displacement change the position of ball leads to the change of the angle of the beam which determines the position angle of a servo motor. Consequently the displacement change of the position of the moving ball and its ensuing change of the angle of the beam results in the change of the position angle of a servo motor. We introduce the fuzzy cascade controller scheme which consists of the outer(1st) controller and the inner(2nd) controller as two cascaded fuzzy controllers, and auto-tune the control parameters(scaling factors) of each fuzzy controller using HFCGA. The inner controller controls the position of lever arm which corresponds to the position angle of a servo motor and the outer controller decides the set-point value of the inner controller. HFCGA is a kind of parallel genetic algorithms(PGAs), and helps alleviate the premature convergence being generated in conventional genetic algorithms (GAs). For a detailed comparative analysis from the viewpoint of the performance results and the design methodology, the proposed method for the ball & beam system which is realized by the fuzzy cascade controller based on HFCGA, is presented in comparison with the conventional PD cascade controller based on serial genetic algorithms.

• 한국의류산업학회지
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• 제10권3호
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• pp.329-334
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• 2008

The purpose of this research is to develop the design, pattern and size system of brief as a measurement garment in order to obtain more precise silhouettes and sizes of the body in 3D measurements. The results of this research are as follows: First, nylon/lycra materials which elasticity is equivalent to 18%(wale) and 27%(course), were selected as a material for briefs to minimize possible error in measurement and deformation of body shape caused by looseness or tightness in its measured parts. And T-back style design was selected, of which briefs neither deform human body nor cause overlapping or excessive tightness when was put on the measurement garment over it. Second, different darts for men and women were adopted into the pattern in consideration for the shape of hip. Third, the waist band of briefs was located between the waistline and abdominal girth line so that it didn't interfere with measurement, and using a wide band of 40mm minimized the tightness of the human body. In addition, the stitch lines and sewing procedure were simplified to minimize the deformation of body shape resulting from inseams and stitch lines. Finally, for the size of briefs, 6 cm intervals were set on the basis of the waist girth and 8 kinds for men and 6 kinds for women were selected in descending order of appearance rate by the interval sections. English T meaning T-back design and numbers representing the waist girth were marked in parallel for the name of size.

• 대한기계학회논문집B
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• 제35권8호
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• pp.799-804
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• 2011

본 논문에서는 자연채광 시스템 LFLP(Linear Fresnel Light Pipe)와 DBLP(Double Blind Light Pipe)시스템을 비교하였다. LFLP시스템은 평행한 빛을 선형프레넬렌즈를 이용하여 선형 형태로 빛으로 집광하여 자연채광에 이용하는 시스템이며, DBLP시스템은 베네시안 형태의 블라인드를 이용하여 빛을 반사시켜 자연채광에 이용하는 시스템이다. DBLP시스템은 LFLP시스템을 개선한 것으로 시스템 앞쪽에 위치한 블라인드는 태양의 고도에 따른 빛을, 뒤쪽에 위치한 블라인드는 태양의 방위각에 따른 빛을 변광부로 반사시키도록 설계 되었다. DBLP시스템의 변광부는 콘모양으로 이루어 져 있으며 블라인드에 의해 반사된 빛을 산광부로 보내주는 역할을 하며, 산광부로 들어온 빛은 실내조명에 사용된다. 따라서 맑은날(clear sky)을 기준으로 두 시스템의 효율을 비교하면 DBLP시스템이 LFLP시스템보다 세배 높게 나오는 것으로 나타났다.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 2002년도 제7차 학술대회 초록집
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• pp.111-111
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• 2002

Purpose： This study is to compare the distinct brain activation between implicit and explicit memory retrieval tasks using a non-invasive blood-oxygenation-level-dependent (BOLD) functional magnetic resonance imaging(fMRI). Materials ＆ Methods： We studied seven right-handed, healthy volunteers aged 21-25 years(mean；22 years) were scanned under a 1.5T Signa Horizon Echospeed MR imager(GE Medical Systems, Milwaukee, U.S.A.). During the implicit and explicit memory retrieval tasks of previously teamed words under the conceptual processing, we acquired fMRI data using gradient-echo EPI with 50ms TE, 3000ms TR, 26cm${\times}$26cm field-of-view, 128${\times}$128 matrix, and ten slices(6mm slice thickness, 1 mm gap) parallel to the AC-PC(anterior commissure and posterior commissure) line. By using the program of statistical parametric mapping(SPM99), functional activation maps were reconstructed and quantified.

• 디지털융복합연구
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• 제17권12호
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• pp.197-202
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• 2019

4차 산업혁명시대에 발맞춰 통신 기술도 5G 기술이 보편화되고 있으며, 5G 기술은 네트워크 슬라이싱, 초다접속 등의 기술을 이용해 4G에 비해 빠른 속도와 응답 속도를 최소화한 기술로 평가 받고 있다. 5G NR은 5G 이동통신 표준을 의미하고, 네트워크 슬라이싱을 통해 네트워크를 병렬연결로 잘라 네트워크를 최적화한다. 또한 기지국 단위에서도 데이터를 처리하게 되면서 해킹에 대한 위험이 증가 되고 있는 실정이다. 또한, 단위면적당 접속 가능한 기기의 수가 기하급수적으로 늘어나므로 단위면적 내 기기 다수 해킹 후 기지국 공격 가능성 또한 존재한다. 이에 해결 방안으로는 양자암호통신 도입, 5G 보안 표준화 등을 본 연구에서 제안하여 안전성과 통신속도를 전부 만족시키는 방안을 제안한다.