• 대한불안의학회지
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• 제3권2호
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• pp.110-115
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• 2007

Objective : The authors examined the treatment response and remission rates in patients with panic disorder after short-term pharmacotherapy in an effort to determine the factors that can be used to predict remission in Korean patients with panic disorder. Methods : Sixty-one patients with panic disorder were recruited for participation in this study. The psychological symptoms of the patients were measured using the HAMA, HAMD, STAIS, STAIT, ASI and API at baseline and after 3 months of pharmacotherapy. Results : Patients with panic disorder showed significantly lower scores on all psychological measures after 3 months of pharmacotherapy with paroxetine. The remission rate was 44.3%, and the response rate was 54.1%. The remitters showed significantly lower HAMD, HAMA, STAIS, STAIT, and ASI scores than the non-remitters. Linear regression analysis revealed that the baseline HAMA, HAMD, and ASI scores could be used to predict the remission rate after controlling for age, sex and agoraphobia. Conclusion : Compared with previous reports, our study showed a similar remission rate in Korean patients with panic disorder. Lower baseline levels of anxiety, depression, and anxiety sensitivity were found to be predictors of treatment remission in panic disorder.

• 동의신경정신과학회지
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• 제26권2호
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• pp.161-170
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• 2015

Objectives: This study was performed to review the research trends in the treatment of panic disorder in traditional Chinese medicine (TCM). Methods: We searched articles in the China National Knowledge Infrastructure (CNKI) from 2004 to 2014. Search key words were '惊恐' and 'panic disorder', and we selected eight studies except for non-clinical, unrelated studies, tests on animals. Results: We finally selected eight articles, and the results were as follows. CCMD-3 was most frequently used as a diagnostic criterion and HAMA was mostly used for outcome measurement. In TCM there are various ways, such as herbal medicine, acupuncture and psychotherapy, to treat panic disorder. Most of the studies showed effective results. Most of the treatment group reported that they had less side effects than the control group. However, the quality of these clinical studies was low. Conclusions: In TCM, research on panic disorder was being conducted more actively than in Korean medicine. According to this study, it seems that in TCM, the treatment of panic disorder might be more effective and have some advantages. Therefore, with this study, we hope to activate more clinical research on the treatment of panic disorder in Korean medicine.

• 동의신경정신과학회지
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• 제29권4호
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• pp.305-314
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• 2018

Objectives: The objective of this study was to report the clinical effectiveness of the complex Korean medicine therapy and M&L (Mindfulness & Loving presence) psychotherapy on the patient with panic disorder. Methods: The subject for this study was the patient diagnosed with panic disorder who complained about intermittent panic attack and accompanying insomnia. During the treatment period, the patient received complex Korean therapy and M&L psychotherapy. The clinical effects were evaluated through Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HDRS), State-Trait Anxiety Inventory (STAI), Panic Disorder Severity Scale (PDSS), and Pittsburgh Sleep Quality Index (PSQI). Results: After the complex Korean medicine therapy and M&L psychotherapy, the overall symptoms of depression, anxiety, panic disorder and insomnia of the patient were lessened in a relatively short period. No specificities or adverse effects were reported during the treatment period. Conclusions: This study established that the complex Korean medicine therapy and M&L psychotherapy was effective in treating patients with panic disorder.

• 동의신경정신과학회지
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• 제16권2호
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• pp.1-11
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• 2005

Objective : This study was to evaluate the clinical improvement of Panic attack and Anticipatory anxiety on Panic Disorder patients after Oriental medical treatment. Methods : We compared post-treatment with pre-treatment on Panic attack and Anticipatory anxiety with Thirty eight Panic Disorder patientsafter Oriental medical treatment - acupunture, herbal medicine, oriental psychotherapy. Results and Conclusions : 1. Foremost herbal medicines were Siwuanshentang(四物安神揚)(39.47%), Qingxinwendantang(情心溫膽揚)(13.16%). Types of demonstration weredeficiency of the heart blood(心血不足)(39.47%), deficiency of qi and blood in the heart and spleen(心脾兩虛)(28.95%), timidity die to insufficiency of qi and deficiency of blood of the heart(心脫虛法)(15.79%), stagnation of phlegm(痰獨阻滯)(13.16%), deficiency of liver-yin and kidney-yin(肝腎陰虛)(2.63%) in order. 2. The physical constitutions in Thirty eight Panic Disorder patients weretwenty nine of Taiyinren(76.3%),six of Shaoyinren(15.8%), three of Shaoyangren(7.9%) in order. 3. This oriental medical treatment was effective in Panic attack from $7.68{\pm}0.87$ to $2.68{\pm}1.613$ and in Anticipatory anxiety from $7.47{\pm}1.006$ to $2.47{\pm}1.841$ in comparison post-treatment with pre-treatment. 4. A percentage of subjective improvement was 72.6%. There were 18.4% in the same, 15.8% in slight improvement, 18.4% in medium improvement, 47.4% in remarkable improvement.

• 동의신경정신과학회지
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• 제26권3호
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• pp.293-306
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• 2015

Objectives: The purpose of this study is to identify predictors of clinical efficacy of oriental medical treatment for patients with panic disorder. Methods: We analyzed medical records of 41 patients who were diagnosed with panic disorder through DSM-IV or ICD-10 by 2 oriental medical neuro-psychiatrists. We performed frequency analysis of demographic characteristics in patients with panic disorder, and assessed the correlation between the psychological scales by Pearson correlation. Repeated measures ANOVA were used to compare the psychological scales during the treatment; and Single regression analysis was used to analyze the factors that have correlation to improvement of panic disorder by oriental medical treatment. Psychological scales used in the study were STAI-X-1/2, STAXI-S/T, BDI2, BAI, BSQ, PAS, ASI, LOT-R, SWLS, LSES and LSMS. Results: Patients' demographic characteristics indicated that there were twice more female than male patients; furthermore, there was a high ratio of patients in their 20s and 30s, with the highest percentage of onset-age in the 20s and average duration of panic disorder from 1~5 years. More than half of the total patient cohort comprised of those who had panic disorder with agoraphobia and major depressive disorder; in addition, major accompanied symptoms were dyspepsia, chest discomfort and headache. After treatment, most scores of psychological scales were significantly reduced, and correlation between the psychological scales was significant. Furthermore, we identified some factors that were significantly correlated to improvement of panic disorder by oriental medical treatment. Conclusions: In conclusion, treatment of panic disorder with oriental medicine was clinically efficient and improved the quality of life.

• 대한불안의학회지
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• 제8권1호
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• pp.9-15
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• 2012

Objectives : The purpose of this study was to assess the health-related quality of life (HRQoL) for patients with panic disorder using EQ-5D and EQ-VAS, and to examine the relationship between health-related quality of life and clinical outcomes following treatment. Methods : 29 patients with panic disorder were recruited from the Seoul Metropolitan area and 20 patients were followed up after two months of outpatient treatment. The Panic Disorder Severity Scale (PDSS) was used to assess the severity of the panic disorder and the changes in symptoms. HRQoL was assessed with EQ-5D and EQ-VAS at baseline and at two months of treatment. Results : All enrolled panic disorder patients showed significantly impairment of HRQoL in view of the subscales of EQ-5D, EQ-VAS index scores. The severity of PDSS was correlated the HRQoL in the panic patients. After treatment, the EQ-5D, EQ-VAS index scores showed significant improvement. Conclusion : Panic disorder patients suffer from lower HRQoL as well as from symptoms of the disorder. They showed clinical improvement and a restored HRQoL with treatment. These outcomes suggest using the EQ-5D, EQ-VAS such as the HRQoL in the assessment of patients with panic disorder is essential.

• 정보처리학회 논문지
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• 제13권7호
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• pp.319-325
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• 2024

본 연구는 공황장애 케어를 위한 모바일 어플리케이션을 개발하여 공황 발작 예방 및 증상 관리를 돕는 것을 목적으로 한다. 공황장애란 지속적인 두려움과 불안, 공황발작 등의 증상을 가지는 심리적 장애로 적절한 치료 및 관리를 필요로 하는 정신질환 중 하나이다. 이에 시공간적 제약 없이 사용할 수 있는 어플리케이션을 통해 사용자가 케어를 받을 수 있는 디지털 치료제의 필요성이 증대되고 있는 추세이다. 연구를 통해 개발된 어플리케이션은 공황장애에 대한 기본적인 정보를 제공하고 자가진단을 통해 상태를 점검할 수 있으며, 다양한 치료법을 제공하여 공황장애 케어를 효과적으로 돕는다. 또한, 사용자 실시간 위치를 기반으로 하여 공황을 일으킨 경험이 있는 장소에 도달할 시 알림을 제공함으로써 개인맞춤형 지원을 제공한다. 본 연구에서 개발된 디지털 치료제를 통해 전통적 치료법에서 벗어난 새로운 도구와 치료법을 제시하고자 한다. 더 나아가 공황장애 뿐만 아니라 정신건강 전 분야에서 디지털 치료제 활용을 도모하며, 사용자들의 삶의 질 향상에 기여할 것으로 기대된다.

• 대한불안의학회지
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• 제9권1호
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• pp.25-30
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• 2013

공황장애 환자에서 12주간의 escitalopram 약물치료 결과, 공황장애 증상은 관해 상태에 이르렀고, 높은 불안민감도와 삶의 질 저하 및 기능장애가 모두 유의하게 호전되었다. 하지만 공황장애 환자들은 약물치료 후에도 여전히 상대적으로 높은 불안민감도와 삶의 질 저하 및 기능장애를 보여서 이의 회복을 위해서는 장기간의 약물치료가 필요할 수 있겠다.

• 동의신경정신과학회지
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• 제25권4호
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• pp.319-332
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• 2014

Objectives: This study was conducted to evaluate the clinical effects of group therapy for Panic disorder patients based on Mindfulness & Li-Gyeung-Byun-Qi therapy. Methods: The FFMQ, BDI, STAI, STAXI, Panic attack, Anticipatory anxiety and subjective improvement of three Panic disorder patients were compared pre- and post-treatment when given Mindfulness & Li-Gyeung-Byun-Qi therapy. Results: 1) After the patient in case 1 underwent 5 weeks of group therapy for Panic disorder, the Mindfulness meditation score was slightly improved, anxiety and depression were significantly decreased, and expression of anger was also improved. In addition, the Panic attack and Anticipatory anxiety became more stable in the objective evaluation, while 'Extreme improvement' was shown in the subjective evaluation. 2) After the patients in case 2 and 3 underwent 5 weeks of group therapy for Panic disorder, Mindfulness meditation scores were slightly improved, anxiety and depression were significantly decreased, and expression of anger was also improved. In addition, the Panic attack and Anticipatory anxiety became more stable in the objective evaluation, while 'Moderate improvements' were shown in the subjective evaluation. Conclusions: As per the results in these cases, it was shown that group therapy for Panic disorder utilizing Mindfulness & Li-Gyeung-Byun-Qi therapy was effective to maintain meditation and control the emotions of anxiety, depression, anger and so on. Therefore, it was considered that expansion of clinical utilization through the standardization of a group therapy program for Panic disorder is needed. Furthermore, it was also considered that a comparative study of the effects of previous cognitive programs for Panic disorder according to the objectified and standardized manual is needed in the future.

• 대한한의학원전학회지
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• 제36권2호
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• pp.49-60
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• 2023

Objectives : This study aims to examine the 13 diagnostic criteria symptoms of panic disorder in Korean Medicine and to establish a literature basis for treating panic disorder in the clinical setting. Methods : Symptoms in Korean Medicine corresponding to each diagnostic criterion were comprehensively reviewed based on the Uihagimmun(醫學入門) and the Donguibogam(東醫寶鑑). Treatments were investigated as well. Results : According to Korean Medicine, panic disorder is believed to be caused by the stagnation of qi, leading to the retention of phlegm and fluids. Conclusions : Yijintang(二陳湯) can serve as a fundamental prescription for treating panic disorder, and it can be easily adapted to each patient's symptoms through modification of the ingredients.