• 한국의류학회지
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• 제33권2호
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• pp.308-318
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• 2009

The purpose of this study was to develop the functionally improved winter work clothing for the Korean railroad workers. Based on the questionnaires, the sample clothing for the Korean railroad workers was produced. The design, materials, and patterns were modified to increase mobility and comfort of workers. Water-repellent treatment was added to the material in order to decrease the dirt and stains while working. Also the reflective strips were added to chest and back of the upper garment in order to increase visibility and safety of the workers. In terms of the design and pattern underarm of the sleeve and side panel of the bodice were put in together and action pleats at the back were inserted in order to decrease the pullback of the armpit and scapular area and increase mobility of the arm movement. Also the patterns of the elbows areas were modified to increase mobility of joint. The prototype was evaluated an objective assessment and subjective assessment to compare to the existing working uniform. Assessment group was consisted of 5 subject groups and 11 expert groups and evaluated external appearance and adaptability to the movements. According to the results, the prototype was evaluated better than the existing working uniform in appearance and adaptability except height of collar. A field test was conducted to compare the prototype and the existing working uniform. The field tests were performed by 6 workers in the Korean railroad. According to the results, the prototype was improved in terms of adaptability and comfort.

• 한국산업보건학회지
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• 제27권4호
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• pp.423-432
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• 2017

Objectives: This study was conducted to evaluate asbestos handling history of workers at automobile manufacturing plants in Korea. Methods: National regulations on asbestos and Korea Occupational Safety and Health Agency(KOSHA) database on the information of asbestos containing products were reviewed. We investigated asbestos related materials from one automobile manufacturing plant. Material safety data sheets(MSDS) collected in 2010, work environment monitoring results reported from 2000 to 2013, trade union reports and asbestos survey reports were reviewed. We also interviewed workers with long career and did walk-through survey. Results: The Ministry of Labor in Korea has permitted asbestos manufacturing since 1990. In 1997, the use of crocidolite and amosite asbestos were banned. In 2007, the Korean government announced a total ban on the manufacturing, importation and use of all kinds of asbestos, which took full effect in 2009. A total of 174 asbestos products information from KOSHA database was analyzed. Extruded cement panel for building, special brake for crane farm machinery, gasket, joint sheet and thermal insulator were produced until 2007. From automobile manufacturing plant survey, we confirmed that asbestos containing materials(ACM) such as gasket, heating induction materials have been used until 2011. Asbestos containing building materials(ACBM) such as bamlites, slate and ceiling tex were reported at 122 asbestos dismantling projects in 2014. Conclusion: Although the use of all kinds of asbestos were banned from 2009, ACMs and ACBMs installed before 2009 were still found at automobile manufacturing plant until 2011 and 2014 respectively. In particular, asbestos slates should be managed because most of slates had not been removed until 2014.

• Genomics & Informatics
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• 제7권1호
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• pp.20-25
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• 2009

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that is characterized by inflammation of the synovial tissue and deterioration of the joint and bone. A recent study reported a potential gene-environment interaction between HLA-DR and smoking. The present study investigated whether a specific gene was related to the association between smoking and the severity of RA (rheumatoid factor levels > 20 IU/ml). We used the resources of the NARAC family collection of GAW 15 databases, and 1139 subjects with RF>20 IU/ml were included in the current analysis. The linkage panel contained 5858 SNP markers, and 5744 SNPs passed quality control criteria. Linear regression analyses, using PLINK software and generalized estimating equation regression models, were used to test for associations between the SNPs and the severity of RA according to smoking groups. Two major findings were established. First, the severity of RA in smokers was associated with rs703618 (p=$6{\times}10^{-5}$), which lies in the intronic region of the stabilin 2 (STAB2) gene on chromosome 12. Second, there were significant differences in the levels of RF between 'ever smokers' and 'never smokers' according to the rs703618 genotype (G/G, A/G, A/A). We investigated whether a specific gene acts as a mediator between smoking and the severity of RA and found that the STAB2 gene could affect this relationship. Our finding indicates that smoking may mediate RA severity by affecting the expression level of a specific gene.

• 한국강구조학회 논문집
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• 제23권4호
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• pp.405-415
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• 2011

건축물의 안전한 내진설계를 위해서는 층간변위비 뿐만 아니라 부재에 요구되는 소성변형을 평가하여야 한다. 본 연구에서는 복잡한 비선형해석 없이 탄성해석을 사용하여 강기둥-약보로 설계된 철골 특수모멘트골조의 보에 요구되는 소성변형을 평가하는 간편한 방법을 개발하였다. 개발한 방법은 탄성해석 결과를 근거로 모멘트 재분배, 기둥 단면치수 및 보 소성힌지 이동, 패널존 변형, 중력하중, 변형경화 거동 등을 고려하여 보의 소성변형각을 직접적으로 예측한다. 또한 가새골조 또는 코어벽 등 횡력 저항구조와 모멘트골조의 상호 작용인 로킹 효과 고려한다. 검증을 위하여 강기둥-약보로 설계된 6층 특수모멘트골조에 제안된 방법을 적용하여 보의 소성변형각을 예측하고, 그 결과를 비선형 해석 결과와 비교하였다. 검증 결과, 제안된 방법은 설계 변수에 따른 보의 소성변형각을 합리적으로 예측하는 것으로 나타났다.

• 대한한방부인과학회지
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• 제34권2호
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• pp.16-30
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• 2021

Objectives: The aim of this study was to establish a clear diagnostic definition of Sanhupung using the Delphi method. Methods: This study used the Delphi technique. A panel consisting of 21 experts of Korean medicine, particularly in of gynecologic medicine, participated in the Delphi examination that included answering the 4th round survey. The Delphi examination was carried out through evaluating and correcting the questionnaire by e-mail. Results: Through the Delphi survey, we have reached on an agreement regarding the basic concepts, time, cause, essential symptoms, and accessory symptoms of Sanhupung. They are as follows: 1) Sanhupung is a culture bound syndrome reflecting Korea's cultural specificity. 2) Sanhupung can be diagnosed even after the miscarriage. 3) For the diagnosis of Sanhupung, the main cause of symptoms should not be classified as other disease. 4) Sanhupung can be diagnosed based on essential symptoms and accessory symptoms. 5) Essential symptoms include local symptoms such as joint pain at specific areas, partial sensory impairment and general symptoms including pain of all the joints, whole body sensory impairment, increased sweating, feeling of wind coming into the body, worsened symptoms with the cold, intolerance to cold, and pain of all the muscles. Conclusions: The basic concepts and diagnostic definition of Sanhupung were suggested based on the Delphi survey among experts in the field. Further research is necessary to improve reliability and validity of diagnostic definition of Sanhupung in clinical trials.

• 자원ㆍ환경경제연구
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• 제31권4호
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• pp.887-908
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• 2022

본 연구는 경제성장과 환경개선 효과를 실증적으로 분석하기 위해 OECD 국가의 이산화황 배출량과 온실가스 배출량, 폐기물 배출량에 대해 환경쿠즈네츠 곡선이 존재하는가를 확인하였다. 패널분석결과, 환경오염물질에 따라 환경쿠즈네츠 곡선의 형태는 다르게 나타났다. 이산화황 배출량은 상대적으로 경제성장의 초기에 정점이 나타나 대부분의 국가가 정점을 지난 역U자형 곡선이 나타나는 반면 온실가스 배출량은 정점을 지나 감소하는 단계이다. 이때 제조업 비중은 온실가스 배출량을 증가시키며, 인구밀도와 연구개발은 배출량을 유의미하게 감소시키는 것으로 분석되었다. 한편, 폐기물에 대해서는 정점을 확인할 수 있는 환경쿠즈네츠 곡선이 존재하지 않았다. 분석대상인 환경오염물질은 각각 오염처리기술, 생산공정 전환, 소비구조 전환에 따라 환경개선 효과가 발생할 수 있는 사례를 대표한다고 보았다. 따라서 본 연구에서는 경제성장과 소득수준 향상이 있더라도 모든 환경오염물질에 대한 자발적인 배출량 감소는 기대하기 어려우며 정점이 지나기 위해서는 추가적인 지구 공동의 노력이 필요하다는 것을 확인하였다. 특히 폐기물은 소득수준보다 인구밀도와 산업구조의 영향이 더 크기 때문에 배출량을 줄이고 자원순환경제를 만들기 위해서는 추가적인 정책적 노력이 필요한 것으로 나타났다.

• 한국터널지하공간학회 논문집
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• 제26권4호
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• pp.315-326
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• 2024

본 연구에서는 터널 붕괴 위험도를 종합적이고 다각적인 관점에서 평가하기 위해 델파이 기법과 AHP (analytic hierarchy process) 기법을 사용하였다. 영향인자 정립은 문헌조사, 선행 연구 및 전문가 집단의 브레인스토밍 과정을 통해 총 5개의 상위분류체계를 구축하였다. 21명의 전문가 패널을 구성하여 총 3차의 델파이 조사 과정을 통해 전문가 판단과정에서 오류 및 편향을 방지하여 신뢰성을 향상시켰다. 최종적으로 전문가 답변에 대한 CVR (content validity ration) 및 COV (coefficient of variation) 분석을 수행하여 총 14개의 영향인자를 도출하였다. 이후 AHP 기법을 적용하여 각 영향인자의 상대적 중요도를 평가하고 최종 복합 가중치를 산정하였다. 지보 및 보강 시행시기가 가장 높은 우선순위를 가지며, 지하수 유입량, 절리면 상태, 지보패턴수준, 보조공법이 그 뒤를 이었다. 이러한 연구 결과를 통해 터널붕괴 위험에 영향을 미치는 주요 요인들을 파악하고, 이를 토대로 터널 안전성을 향상시키는 전략을 수립하는데 도움이 될 것으로 기대된다.

• Journal of Applied Biological Chemistry
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• 제59권3호
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• pp.189-201
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• 2016

과일류 가공 중 농약의 가공계수는 과일 가공품의 농약 기준 설정에 사용된다. 본 연구는 2010년부터 2014년까지 JMPR의 가공식품 중 잔류농약 가공계수 자료를 고찰하였다. 사과의 세척, 건조, 통조림, 주스, 소스, 퓌레 및 Pomace 가공 중 19종 농약의 가공계수를 비교하였다. Pomace를 제외한 사과가공품은 대부분 가공계수가 1 이하의 결과를 보였다. 포도의 세척, 주스, 포도주, 건포도 및 Pomace 가공 중 21종 농약의 가공계수를 평가하였다. 건포도의 가공계수는 대부분 1 이상으로 나타났다. 오렌지의 주스, 오일 및 마말레이드 등 가공 중 19종 농약의 가공계수를 평가한 결과, 오일의 가공계수가 1 이상으로 나타났다. 토마토의 주스, 퓌레 및 페이스트 등 가공 중 27종 농약의 가공계수를 비교한 결과, Pomace를 제외하고 페이스트의 가공계수가 가장 높게 나타났다. 자두의 세척, 건조 및 퓌레 과정 중 12종 농약의 가공계수는 건조에서 대부분 1 이상으로 나타났다. 농약의 지용성과 휘발성 같은 물리적인 특성과 과일 가공 중 가공계수는 사과 주스, 오렌지 주스, 토마토 퓌레와 페이스트 및 딸기잼 가공에서 유의적인 상관관계가 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1693-1697
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• 2012

Objective: To explore the effect on radiosensitivity of arsenic trioxide ($As_20_3$) in conjunction with hyperthermia on the esophageal carcinoma EC-1 cell line. Method: Inhibition of EC-1 cell proliferation at different concentrations of $As_20_3$ was assessed using the methyl thiazolyl blue colorimetric method (MTT method), with calculation of $IC_{50}$ value and choice of 20% of the $IC_{50}$ as the experimental drug concentration. Blank control, $As_20_3$, hyperthermia, radiotherapy group, $As_20_3$ + hyperthermia, $As_20_3$ + radiotherapy, hyperthermia + radiotherapy and $As_20_3$ + hyperthermia + radiotherapy groups were established, and the cell survival fraction (SF) was calculated from flat panel colony forming analysis, and fitted by the 'multitarget click mathematical model'. Flow cytometry (FCM) was used to detect changes in cell apoptosis and the cell cycle. Results: $As_20_3$ exerted inhibitory effects on proliferation of esophageal carcinoma EC-1 cells, with an $IC_{50}$ of 18.7 ${\mu}mol/L$. After joint therapy of $As_20_3$ + hyperthermia + radiotherapy, the results of FCM showed that cells could be arrested in the $G_2$/M phase, and as the ratio of cells in $G_0/G_1$ and S phases decreased, cell death became more pronounced. Conclusion: $As_20_3$ and hyperthermia exert radiosensitivity effects on esophageal carcinoma EC-1 cells, with synergy in combination. Mechanistically, $As_20_3$ and hyperthermia mainly influence the cell cycle distribution of EC-1 esophageal carcinoma cells, decreasing the repair of sublethal damage and inducing apoptosis, thereby enhancing the killing effects of radioactive rays.

• Design & Manufacturing
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• 제14권1호
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• pp.8-14
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• 2020

In general, auto parts production assembly line is assembled and produced by automatic mounting by an automated robot. In such a production site, quality problems such as misalignment of parts (doors, trunks, roofs, etc.) to be assembled with the vehicle body or collision between assembly robots and components are often caused. In order to solve such a problem, the quality of parts is manually inspected by using mechanical jig devices outside the automated production line. Automotive inspection technology is the most commonly used field of vision, which includes surface inspection such as mounting hole spacing and defect detection, body panel dents and bends. It is used for guiding, providing location information to the robot controller to adjust the robot's path to improve process productivity and manufacturing flexibility. The most difficult weighing and measuring technology is to calibrate the surface analysis and position and characteristics between parts by storing images of the part to be measured that enters the camera's field of view mounted on the side or top of the part. The problem of the machine vision device applied to the automobile production line is that the lighting conditions inside the factory are severely changed due to various weather changes such as morning-evening, rainy days and sunny days through the exterior window of the assembly production plant. In addition, since the material of the vehicle body parts is a steel sheet, the reflection of light is very severe, which causes a problem in that the quality of the captured image is greatly changed even with a small light change. In this study, the distance between the car body and the door part and the door are acquired by the measuring device combining the laser slit light source and the LED pattern light source. The result is transferred to the joint robot for assembling parts at the optimum position between parts, and the assembly is done at the optimal position by changing the angle and step.