• Title/Summary/Keyword: pKa value

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Change of energy consumption according to loading on the ankle of normal adults during gait (정상 성인의 발목에 부가된 하중에 의한 보행 중 에너지 소모도 변화)

  • Kim Bong-Ok;Chae Su-Sung;Kim Yong-Gun;Han Dong-Uck
    • The Journal of Korean Physical Therapy
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    • v.11 no.2
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    • pp.43-50
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    • 1999
  • The purpose of this study was to evaluate the change of the energy consumption when loading to leg of the 60persons who don't have past history of cardiopulmonary and neuromuscular disease, To evaluate the change or energy consumption, heart rate was measured in sitting position for 5minute, during walking for 3minute at for 4.8km on treadmill, and during resting state after walking with 1Kg loading to right ankle, and the other 1Kg loading was added to left ankle and then heart rates were measured in the The results were as follow; 1. PCI value without loading to Ankle were significantly increased compared to 1Kg, and 2Kg. (p<0.05) 2. Female Subjects showed mon increased PCI value in without leading and 2Kg loading compared to male subjects. ( p<0.05) 3. When 1Kg ana 2Ka loading to ankle significantly differences were showed between them. (p<0.05) 4. In the case of 1Kg and 2Kg loading, the difference among age groups was observed and the significant difference among PCI, PCI 1kg, PCI 2kg was showed in the only group that is less than 30 years old. 5. In every PCI condition the difference among height groups was observed and the significant difference among PCI conditions was showed in the only group that is less than 165cm. 6. The difference among weight groups in each PCI condition was not observed, but the significant differences among PCI conditions was showed in every group except the group that h from 60kg to 69kg. These results showed that energy consumption was increased according to loading on the ankle during Sate so weight of orthosis or prosthesis met be considered when choosing them and during gait training with these ones.

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Removal Characteristics of Endocrine Disrupting Compounds (EDCs), Pharmaceutically Active Compounds (PhACs) and Personal Care Products (PCPs) by NF Membrane (NF막을 이용한 EDCs, PhACs, PCPs 물질의 제거 특성 평가)

  • Jang, Hyuewon;Park, Chanhyuk;Hong, Seungkwan;Yoon, Yeomin;Jung, Jin-Young;Chung, Yun-Chul
    • Journal of Korean Society of Water and Wastewater
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    • v.21 no.3
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    • pp.349-357
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    • 2007
  • Reports of endocrine disrupting compounds (EDCs), pharmaceutically active compounds (PhACs), and personal care products (PCPs) have raised substantial concern in important potable drinking water quality issues. Our study investigates the removal of EDCs, PhACs, and PCPs of 10 compounds having different physico-chemical properties (e.g., molecular weight, and octanol-water partition coefficient ($K_{OW}$)) by nanofiltration (NF) membranes. The rejection of micropollutants by NF membranes ranged from 93.9% to 99.9% depending on solute characteristics. A batch adsorption experiments indicated that adsorption is an important mechanism for transport/removal of relatively hydrophobic compounds, and is related to the octanol-water partition coefficient values. The transport phenomenon associated with adsorption may also depend on solution water chemistry such as pH and ionic strength influencing the pKa value of compounds. In addition, it was visually seen that the retention was somewhat higher for the larger compounds based on their molecular weight. These results suggest that the NF membrane retains many organic compounds due to both hydrophobic adsorption and size exclusion mechanisms.

Line${\times}$Tester Analysis of Certain Quantitative Traits in Silkworm Bombyx mori L. under Optimum and Stress Rearing Conditions

  • Rao, P.Sudhakara;Datta, R.K.;Kumari, K.M.Vijaya;Palit, A.K.;Bhat, S.A.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.8 no.1
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    • pp.107-112
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    • 2004
  • The combining abilities in the 5 newly evolved thermo tolerant breeds viz., SR6, SR7, SR8 SR9 and SR10 of silkworm Bombyx mori L. and their 15 hybrids were made in a line${\times}$tester crossing programme. Data were analysed for seven quantitative traits i.e., pupation rate, cocoon yield, cocoon weight, cocoon shell weight, cocoon shell ratio, filament length and raw silk percentage under optimum room temperature $(25{\pm}{1^{\circ}C})$ conditions (In case of high temperature $(36{\pm}{1^{\circ}C})$ stress conditions five economic traits except filament length and raw silk percentage) with 3 widely adapted testers i.e., KA, CSR2 and CC1 as lines (females) and testers (males) respectively. The performance at high temperature and low humidity conditions aye only taken into consideration for selecting the best lines/hybrids. Among the lines SR6 exhibited positive General combining ability (GCA) effects for pupation rate, cocoon yield, cocoon weight and cocoon shell ratio traits, followed by SR7 for pupation rate, cocoon yield and cocoon shell weight and cocoon shell ratio. Among testers, KA exhibited positive GCA effects for two quantitative traits cocoon yield, cocoon weight and CSR2 for cocoon shell weight and cocoon shell ratio under adverse temperature conditions. The hybrid SR6${\times}$CC1 and SR7${\times}$CSR2 exhibited significant positive Specific combining ability (SCA) effects for majority of the traits in high temperature stress conditions of rearing. The better parent value of heterosis(Heterobeltiosis) was exhibited by the hybrid SR6${\times}$CC1 for pupation rate, cocoon yield, cocoon weight and cocoon shell weight and SR7${\times}$CSR2 for all the trails evaluated under high temperature conditions. Based on the results, the lines SR6 and SR7 was judged as best combiners and the hybrids SR6${\times}$CC1 and SR7${\times}$CSR2 can be selected for commercial exploitation in tropical climate.

Drainage Performance of Various Subsurface Drain Materials- (배수개선공법개발에 관한 연구(I) -각종 지하배수용 암거재료의 배수성능-)

  • 김철회;이근후;유시조;서원명
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.21 no.3
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    • pp.104-120
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    • 1979
  • I. Title of the Study Studies on the Development of Improved Subsurface Drainage Methods. -Drainage Performance of Various Subsurface Drain Materials- II. Object of the Study Studies were carried out to select the drain material having the highest performance of drainage; And to develop the water budget model which is necessary for the planning of the drainage project and the establishment of water management standards in the water-logged paddy field. III. Content and Scope of the Study 1. The experiment was carried out in the laboratory by using a sand tank model. The drainage performance of various drain materials was compared evaluated. 2. A water budget model was established. Various parameters necessary for the model were investigated by analyzing existing data and measured data from the experimental field. The adaptability of the model was evaluated by comparing the estimated values to the field data. IV. Results and Recommendations 1. A corrugated tube enveloped with gravel or mat showed the highest drainage performance among the eight materials submmitted for the experiment. 2. The drainage performance of the long cement tile(50 cm long) was higher than that of the short cement tile(25 cm long). 3. Rice bran was superior to gravel in its' drain performance. 4. No difference was shown between a grave envelope and a P.V.C. wool mat in their performance of drainage. Continues investigation is needed to clarify the envelope performance. 5. All the results described above were obtained from the laboratory tests. A field test is recommended to confirm the results obtained. 6. As a water balance model of a given soil profile, the soil moisture depletion D, could be represented as follows; $$D=\Sigma\limit_{t=1}^{n}(Et-R_{\ell}-I+W_d)..........(17)$$ 7. Among the various empirical formulae for potential evapotranspiration, Penman's formular was best fit to the data observed with the evaporation pans in Jinju area. High degree of positive correlation between Penman;s predicted data and observed data was confirmed. The regression equation was Y=1.4X-22.86, where Y represents evaporation rate from small pan, in mm/100 days, and X represents potential evapotranspiration rate estimated by Penman's formular. The coefficient of correlation was r=0.94.** 8. To estimate evapotranspiration in the field, the consumptive use coefficient, Kc, was introduced. Kc was defined by the function of the characteristics of the crop soil as follows; $Kc=Kco{\cdot}Ka+Ks..........(20)$ where, Kco, Ka ans Ks represents the crop coefficient, the soil moisture coefficient, and the correction coefficient, respectively. The value of Kco and Ka was obtained from the Fig.16 and the Fig.17, respectively. And, if $Kco{\cdot}Ka{\geq}1.0,$ then Ks=0, otherwise, Ks value was estimated by using the relation; $Ks=1-Kco{\cdot}Ka$. 9. Into type formular, $r_t=\frac{R_{24}}{24}(\frac{b}{\sqrt{t}+a})$, was the best fit one to estimate the probable rainfall intensity when daily rainfall and rainfall durations are given as input data, The coefficient a and b are shown on the Table 16. 10. Japanese type formular, $I_t=\frac{b}{\sqrt{t}+a}$, was the best fit one to estimate the probable rainfall intensity when the rainfall duration only was given. The coefficient a and b are shown on the Table 17. 11. Effective rainfall, Re, was estimated by using following relationships; Re=D, if $R-D\geq}0$, otherwise, Re=R. 12. The difference of rainfall amount from soil moisture depletion was considered as the amount of drainage required. In this case, when Wd=O, Equation 24 was used, otherwise two to three days of lag time was considered and correction was made by use of storage coefficient. 13. To evaluate the model, measured data and estimated data was compared, and relative error was computed. 5.5 percent The relative error was 5.5 percent. 14. By considering the water budget in Jinju area, it was shown that the evaporation amount was greater than the rainfall during period of October to March in next year. This was the behind reasonning that the improvement of surface drainage system is needed in Jinju area.

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Effects of Urea and Ammonium Sulfate Application on Yield and Nutritive Value of Whole Crop Barley in Reclaimed Tideland (간척지에서 요소 및 유안비료 시용이 총체보리의 생산성과 사료가치에 미치는 영향)

  • Shin Jae-Soon;Kim Won-Ho;Lee Seung-Heon;Lim Young-Chul
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.26 no.1
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    • pp.25-30
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    • 2006
  • This experiment was conducted to compare the fresh yield and dry matter yield, and nutritive values of whole crop barley treated with Urea (200 kg/ha, T2) and ammonium sulfate fertilizer as 200 kg/ha (T3), 300 kg/ha (T4) and 400 kg/ha (T5) at the Bae-Ho reclaimed tideland. Korea from 2003 to 2005. Salt contents of soil in the ammonium sulfate plots (T3, T4, T5) were lower than those of T2. The fresh yields of ammonium sulfate plots (T3, T4, T5) were higher than those of T2 as 62% (p>0.05), 41% (p>0.05) and 23% (p<0.05), respectively. The dry matter yield of T3, T4 and T5 (ammonium sulfate) was significantly (p<0.05) higher at 5,080 kg/ha, 4,667 ka/ha, 4,040 kg/ha, respectively. The total digestible nutrients (TDN) yield tends to have a similar result. Crude protein (CP) content was highest in T3 and CP trends to decrease as the level of ammonium sulfate was increased. Total digestible nutrient (TDN) were high in T3 and T4. The sodium content of T3 and T4 were lower than T2. Based on the study, it was more desirable to use ammonium sulfate (200 kg N/ha) rather than Urea as fertilizer on reclaimed land in terms of forage production and nutritive value.

Effects of Xanthan Gum and Guar Gum on the Quality Characteristics of Gluten-free Bread using Teff (Eragrostis tef) Flour (Teff (Eragrostis tef) 분말을 이용한 Gluten-free 식빵의 품질 특성에 잔탄검과 구아검이 미치는 영향)

  • Joung, Ki Youeng;Song, Ka-Young;O, Hyeonbin;Shin, So Yeon;Kim, Young-Soon
    • Culinary science and hospitality research
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    • v.23 no.3
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    • pp.147-157
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    • 2017
  • This study investigated quality characteristics and sensory properties of gluten-free bread using teff flour and various gums. The five samples used in this study were control (wheat flour), T (teff flour), TG (teff flour, guar gum), TX (teff flour, xanthan gum), and TGX (teff flour, guar gum, xanthan gum). Baking loss, moisture content, pH, salinity, brix, dough expansion, color value, texture property, and sensory property were measured for each sample. As a result, pH was the highest in TX at 6.11 and the lowest in the control at 5.77. Salinity was the highest in the control at 0.80% and lowest in TG at 0.04%. Brix was the lowest in TX at $1.10^{\circ}Bx$. While moisture content was the highest in the control at 43.58%, gluten-free breads using teff flour had no significant difference (p<0.05). Baking loss rate of bread was no significant difference among samples (p<0.05). Dough expansion rate by fermentation was the highest in the control at 108.89% and the lowest in T at 17.84%. L-value of crust had no significant difference (p<0.05). For L-value of crumb, the control was the highest at 64.34 and T was the lowest at 33.84. In texture properties analysis, hardness was the highest in TGX at 16.00 N and the lowest in the control at 2.87 N. There was no significant difference in springiness (p<0.05). Chewiness was the highest in TX and TGX. The result of sensory properties was that while there were no significant differences in color, salty taste, flavor, and overall acceptability, there was a significant difference in softness and sweetness (p<0.05). These results showed that use of teff flour and gums rather than using only teff flour for bread manufacturing can improve quality characteristics in dough expansion and texture properties. It is considered that xanthan gum or guar gum are appropriate on bread using teff for quality characteristics.

Quality Properties and Antioxidant Activities of Chocolate with Variable Leaf Powder (잎채소 분말을 첨가한 초콜릿의 품질특성 및 항산화 활성)

  • O, Hyeonbin;Song, Ka-Young;Zhang, Yangyang;Joung, Ki Youeng;Shin, So Yeon;Kim, Young-Soon
    • Korean journal of food and cookery science
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    • v.33 no.3
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    • pp.247-255
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    • 2017
  • Purpose: The aim of this study was to investigate the effects of various leaf powders on chocolate by analyzing quality characteristics, antioxidant activities, and sensory characteristics. Methods: Pine needles, mulberry leaves, ramie leaves, barley leaves, and squash leaves were freeze-dried, powdered, and added to the chocolate. Results: Water contents of all leaf powder-added groups were significantly higher than that of the control (15.78%). The pH values of chocolate with leaf powder were lower than that of the control (6.33) while that of mulberry leaf chocolate (6.56) was higher than that of the control. In color measurement, L-value, a-value, and b-value were highest in pine needle chocolate (30.31, 3.52, and 4.78, respectively). The ${\Delta}E$ value (total color difference compared to white board) was the highest in squash leaf chocolate (69.51) and significantly different from that of the control (67.69). The hardness of leaf powder-added chocolate was lower than that of the control (6.84 N), except for pine needles. In the antioxidant activity analysis, chocolate with pine needles and squash leaves had higher polyphenols, flavonoids, and ABTS radical scavenging antioxidant activity than those of the control. Overall consumer acceptability was the most preferred in the control compared to the other groups. However, chocolate with mulberry and barley leaves also received high scores (5.60 and 5.40, respectively) for overall acceptability. Conclusion: It can be concluded that chocolate with barley leaves is desirable for making functional chocolate due to its high consumer preference and positive effects on improving antioxidant activities.

EVALUATION OF FLUORIDE-RELEASING CAPACITY FROM POLYVINYL ALCOHOL POLYMER TAPE SUPPLEMENTED WITH NAF IN ORAL CAVITY (폴리비닐알코올 기반 고분자 불소 함유 테이프의 구강 내 불소 유리 성능 평가)

  • Lee, Ka-Young;Lee, Sang-Ho;Lee, Nan-Young
    • Journal of the korean academy of Pediatric Dentistry
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    • v.40 no.2
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    • pp.89-97
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    • 2013
  • The purpose of this study is to investigate fluoride release in the oral cavity from polymer adhesive tape which is NaF coated PVA. 45 healthy adults were divided into 3 groups by the type of topical fluoride applied: 60seconds taste$^{(R)}$ APF gel (group 1), FluoroDose$^{(R)}$ varnish (group 2) and NaF-PVA (group 3). Topical fluoride was applied to the facial surface of maxillary 12 teeth and unstimulated whole saliva was collected to measure fluoride release after 1, 3, 6, 12, 24, and 48 hours. Fluoride-sensitive electrode was used for measuring the fluoride concentration in the saliva samples. All three groups showed significantly higher value for fluoride concentration than the baseline after 1 and 3 hours (p < 0.05). After 6 hours, group 3 showed significantly higher fluoride concentration than the baseline (p < 0.05) and also showed significantly higher value for fluoride concentration than group 1 and group 2. Between group 1 and group 2, however, there was no significant difference statistically with respect to fluoride concentration value (p > 0.05).

Structural basis of novel TRP14, thioredoxin-related protein that regulates TNE-$\alpha$ signaling pathways

  • Woo, Joo-Rang;Jeong, Woo-Jin;Rhee, Sue-Goo;Ryu, Seong-Eon
    • Proceedings of the Korea Crystallographic Association Conference
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    • 2003.05a
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    • pp.18-18
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    • 2003
  • Thioredoxin (Trx) is a small redox protein that is ubiquitously distributed from achaes to human. In diverse organisms, the protein is involved in various physiological roles by acting as electron donor and regulators of transcription and apoptosis as well as antioxidants. Sequences of Trx within various species are 27~69% identical to that of E. coli and all Trx proteins have the same overall fold, which consists of central five β strands surrounded by four α helices. The N-terminal cysteine in WCGPC motif of Trx is redox sensitive and the motif is highly conserved. Compared with general cysteine, the N-terminal cysteine has low pKa value. The result leads to increased reduction activity of protein. Recently, novel thio.edoxin-related protein (TRP14) was found from rat brain. TRP14 acts as disulfide reductase like Trx1, and its redox potential and pKa are similar to those of Trx1. However, TRP14 takes up electrons from cytosolic thioredoxin reductase (TrxR1), not from the mitochondrial thioredoxin reductase (TrxR2). Biological roles of TES14 were reported to be involved in regulating TNF-α induced signaling pathways in different manner with Trx1. In depletion experiments, depletion of TRP14 increased TNF-α induced phosphorylation and degradation of IκBα more than the depletion Trx1 did. It also facilitated activation of JNK and p38 MAP kinase induced by TNF-α. Unlike Trx1, TRP14 shows neither interaction nor interference with ASK1. Here, we determined three-dimensional crystal structure of TRP14 by MAD method at 1.8Å. The structure reveals that the conserved cis-Pro (Pro90) and active site-W-C-X-X-C motif, which may be involved in substrate recognition similar to Trx1 , are located at the beginning position of strand β4 and helix α2, respectively. The TRP14 structure also shows that surface of TRP14 in the vicinity of the active site, which is surrounded by an extended flexible loop and an additional short a helix, is different from that of Trx1. In addition, the structure exhibits that TRP14 interact with a distinct target proteins compared with Trx1 and the binding may depend mainly on hydrophobic and charge interactions. Consequently, the structure supports biological data that the TRP14 is involved in regulating TNF-α induced signaling pathways in different manner with Trx1.

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Effect of Flask Type on the Production of Value-added Hydroxy Fatty Acid by Pseudomonas aeruginosa PR3 (Pseudomonas aeruginosa PR3에 의한 기능성지방산 Hydroxy fatty acid 생산에 있어 배양용기 형태에 따른 영향)

  • Baek, Ka-Yeon;Son, Hye-Ran;Kim, Hak-Ryul
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.2
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    • pp.114-122
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    • 2010
  • Hydroxy fatty acids have gained important attentions because of their special properties such as higher viscosity and reactivity compared to non-hydroxy fatty acids. The new bacterial isolate Pseudomonas aeruginosa (PR3) had been well studied to produce mono-, di-, and tri-hydroxy fatty acids from different unsaturated fatty acids. Of those hydroxy fatty acids, 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) was produced with high yield from oleic acid by P. aeruginosa PR3. Mostly, the substrates used for the production of hydroxy fatty acid by microorganisms were free fatty acids or synthetic lipids. However, it is highly plausible to use vegetable oils containing oleic acid such as olive oil for DOD production by P. aeruginosa PR3. As a first step to address the utilization of olive oil as a substrate for DOD production, we tried to determine the effect of vessel type on DOD production from olive oil by P. aeruginosa PR3. Of two different flask types of normal flask and baffled-flask, baffled-flask was highly effective for DOD production with all the media tested. Maximum increase of productivity by baffled-flask represented 221% with the medium supplemented with whey powder instead of lactose. Results from this study demonstrated that vessel type and medium composition could be both significant factors for DOD production from olive oil by P. aeruginosa PR3.