• Journal of Sensor Science and Technology
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• v.21 no.3
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• pp.186-191
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• 2012

In this paper, we present a pH measurement method that uses a microcantilever-array-based biosensor system. It is composed of microcantilever array, liquid cell, micro syringe pump, laser diode array, position sensitive detector, data acquisition device, and data processing software. Four microcantilevers are functionalized with pH-sensitive MHA(mercaptohexadecanoic acid) as a probe, while three microcantilevers are functionalized with HDT(hexadecane thiol) as reference. We prepare PBS(phosphate buffered saline) solutions of different pH and inject them into the liquid cell with a predefined volumetric speed at regular time intervals. The functionalized mircocantilevers in the liquid cell deflect as a self-assembled monolayer on the microcantilever binds with probe molecules in the solution. The difference in deflection between the MHA-covered probe microcantilever and the HDT-covered reference microcantilever was used to compensate for thermal drift. The deflection difference clearly increases with increasing pH in the solution. It was shown that when the pH values of the PBS solutions are high, there were large variations in the deflection of microcantilevers, whereas there were small variations for low pH value. The experimental results show that the microcantilever array functionalized with MHA and HDT can detect pH value with good repeatability.

• Journal of IKEEE
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• v.17 no.4
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• pp.398-406
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• 2013

Nuclear medicine imaging devices such as PET diagnose disease after injecting radiopharmaceuticals in human body for diagnosis. Radiopharmaceuticals should maintain the proper pH for human body safety. In general, pH paper is used to measure the pH of the radiopharmaceutical. pH of the sample compared with the standard color chart is used for measurement. However, the pH reading difference according to the experience of a rater can be generated. Also, a pH meter for measuring pH has a high sensitivity and contamination of the sensor must be avoided. In this paper, we developed the new hardware device for pH reading method and software was developed with vision algorithm to measure pH easily and simply.

• Analytical Science and Technology
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• v.6 no.3
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• pp.313-318
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• 1993

The rose petal tissue biosensor has been constructed by immobilizing New carina rose tissue. Optimum conditions for the determination of urea were investigated using this sensor. Selectivity and life time of this sensor were also obtained. As a result, the biosensor showed the optimum response characteristics in 0.20M phosphate buffer solution at pH 8.0, $37^{\circ}C$ and 50mg of tissue amounts. This sensor was linear from $9.0{\times}10^{-5}$ to $4.0{\times}10^{-3}M$ urea with a slope of 42mV/decade. The limit of detection and response time are $7.0{\times}10^{-5}M$ and 17~19 min.

• Journal of Electrochemical Science and Technology
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• v.14 no.1
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• pp.66-74
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• 2023

In this study, a new potentiometric sensor selective to copper(II) ions was developed and characterized. The developed sensor has a polymeric membrane and contains 4.0% electroactive material (ionophore), 33.0% poly(vinyl chloride) (PVC), 63.0% bis(2-ethylhexyl)sebacate (BEHS) and 1.0% potassium tetrakis(p-chlorophenyl)borate (KTpClPB). This novel copper(II)-selective sensor exhibits a Nernstian response over a wide concentration range from 1.0×10^-6 to 1.0×10^-1 mol L^-1 with a slope of 29.6 (±1.2) mV decade^-1, and a lower detection limit of 8.75×10-7 mol L^-1. The sensor, which was produced economically by synthesizing the ionophore in the laboratory, has a good selectivity and repeatability, fast response time and stable potentiometric behaviour. The potential response of the sensor remains unaffected of pH in the range of 5.0-10.0. Based on the analytical applications of the sensor, we showed that it can be used as an indicator electrode in the quantification of Cu²⁺ ions by potentiometric titration against EDTA, and can also be successfully utilized for the determination of copper(II) ions in different real samples.

• Applied Chemistry for Engineering
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• v.1 no.2
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• pp.154-160
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• 1990

Hydroxypropyl methacrylate polymeric membranes having tertiary amine moiety were prepared to control the release rate of insulin in response to the concentration of glucose. Hydroxypropyl methacrylate was copolymerized with N, N'-diethylaminoethylacrylate. Its water content was increased with decreasing the pH of the medium and was reversible with variation of the pH of the medium. The permeation coefficient of insulin through copolymer membrane was also increased with decreasing the pH of the medium. Combining this copolymer membrane and the glucose oxidase immobilized membrane as a sensor for glucose, composite membrane was prepared. The permeability of this composite membrane was increased with addition of glucose.

• Analytical Science and Technology
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• v.14 no.3
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• pp.286-289
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• 2001

The effect of pH and the substrate concentration on the sensing ability of the chicken peroxidase enzyme electrode was examined quanititatively. Using the new Michaelis-Menten equation, to which pH concept was introduced, enabled to calculate all kinds of dissociation constant related to chicken peroxidase and subsequently to determine the optimum pH of the sensor.

• Proceedings of the KIEE Conference
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• 2004.07c
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• pp.1762-1765
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• 2004

This paper suggest the field test method of PD UHF sensor's sensitivity for a high voltage GIS and prove a reliability of the field test method through the test results of UHF sensor.

• Proceedings of the KIEE Conference
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• 1999.11d
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• pp.956-958
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• 1999

We designed and fabricated p-type MOSFETs with floating gate in n-type well lesion and examined their photo characteristics. The fabricated MOBFETs showed a high photo-respsonse characteristics, indicating a possibility as a photo sensor. The structures of MOSFETs were changed as to the number of gate and channel. As the number of channel increased, the induced current by light source s increased. However, the effect of the number of gate was negligble on the photo-response characteristics of the device.

• Proceedings of the KIEE Conference
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• 2004.05b
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• pp.121-124
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• 2004

This paper suggest the field test method of PD UHF sensor's sensitivity for a high voltage GIS and prove a reliability of the field test method through the test results of UHF sensor.

• Bulletin of the Korean Chemical Society
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• v.30 no.12
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• pp.2979-2983
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• 2009

Nanowires of polytetrakis(o-aminophenyl)porphyrin (PTAPPNW) were fabricated by electrochemical polymerization with the cyclic voltammetric method in anodic aluminum oxide (AAO) membranes. The glassy carbon electrode (GCE) modified by PTAPPNW, single-walled carbon nanotubes (SWNT) and Nafion as a binder was investigated with voltammetric methods in a phosphate buffer saline (PBS) solution at pH 7.4. The PTAPPNW + SWNT + Nafion/GCE exhibited strongly enhanced voltammetric and amperometric sensitivity towards hydrogen peroxide ($H_2O_2$), which shortened the response time and enhanced the sensitivity for $H_2O_2$ determination at an applied potential of 0.0 V by amperometric method. The PTAPPNW + SWNT + Nafion/GCE can be used to monitor $H_2O_2$ at very low concentrations in biological pH as an efficient electrochemical $H_2O_2$ sensor.