• Title/Summary/Keyword: pH 조절

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Effect of the Viscosity of (Hydroxypropyl)methyl Cellulose on Dissolution Rate of Alfuzosin-HCl Granule Tablet (HPMC의 점도에 따른 염산 알푸조신 과립정제의 용출률 조절)

  • Kim, Won;Song, Byung-Joo;Kim, Dae-Sung;Kim, Su-Jin;Lee, Seon-Kyoung;Kim, Hye-Lin;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.34 no.3
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    • pp.269-273
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    • 2010
  • The primary objective of this work is to find the optimal condition for the granule tablet formulation of alfuzosin-HCl that aims to achieve a sustained drug release. (Hydroxypropyl)methyl cellulose (HPMC) is one of the most widely used polymer as a drug formulation and therefore has been utilized in this study as an excipient. Alfuzosin-HCl granule tablet was developed using the various viscosities of HPMC and the effects of viscosity on drug release was investigated. Fourier transform-infrared (FTIR) and X-ray diffraction (XRD) were employed to investigate the chemical structure and crystallization of alfuzosin-HCl in the formulation. We prepared the granule tablet by a direct compression method and studied the release profile in the stimulated intestinal fluid (pH 6.8). As the viscosity of HPMC increased the release of alfuzosin-HCl decreased, demonstrating that controlled release of alfuzosin-HCl can be achieved by varying the viscosity of HPMC.

The Correlation between Uneven Ripening and Respiration Rate of Tomato at Breaker Stages (Breaker 단계 토마토의 착색불량과 호흡률간 상관관계)

  • Kang, Ho-Min;Kim, Young-Shik
    • Journal of Bio-Environment Control
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    • v.19 no.2
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    • pp.93-96
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    • 2010
  • Breaker stage tomato fruits that were stored at low temperatures show typical chilling symptoms such as uneven ripening and a high respiration. Experiments were performed to assess and compare these chilling injury symptoms of breaker stage tomato fruits, and to gather basic data that can be used to decide whether horticultural crops receive chilling injuries. Tomato fruits that had been sorted in the breaker stage were stored at $2^{\circ}C$ for 0, 3, 6, and 9 days, and then their respiration rates were measured at 3, 6, 9, 12, 24, 36, and 48 h after moving them to room temperature. This treatment was repeated twice on the same procedures, except the storage periods, which were changed to 0, 1, 2, 3, and 10 days. The respiration rate was increased in a 1 day storage treatment, and the increasing rate rose higher with extended storage periods. The $a^*$ value, which represents the surface color of tomato fruits, was measured 10 days after moving to them into room temperature. Those with an increased $a^*$ value rate got dull and showed uneven coloring after 2 days' storage treatment. These two factors, the respiration rate and $a^*$ value of the surface, showed a high correlation (r = 0.9716, p < 0.001). Therefore, the chilling injury of breaker stage tomato fruits can be diagnosed by measuring the respiration rate after moving them into room temperature, and the degree of chilling injury can also be assessed in terms of the respiration increase rate.

Status of Automatization in Protected Horticultural Facilities and Prospect of Plant Factory in Korea (한국의 원예시설 자동화 현황 및 식물공장의 발전방향)

  • 윤진하
    • Proceedings of the Korean Society for Bio-Environment Control Conference
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    • 1996.05a
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    • pp.91-115
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    • 1996
  • In the recent years, protected horticultural facilities have been modernized and glasshouses are also propagating in Korea, even most vegetables production are conducted in the traditional plastic houses covered with, for example, PVC film for just temperature keeping. It would limit the productivity and competitivity of the vegetable production industry without automatization and high quality year round production. A plant factory, aimed to produce vegetables in the limited areas, was initiated in Christensen farm, Denmark in 1957, and widely propagated in some developed countries. As it has the automatized system which enables to keep optimized environment conditions, it will be the best facility for high quality products as well as year round planned production. However, we have not even started the plant factory production. Since the plant factory is requiring lots of resources, besides plant cultivation technologies, such as environment control, automatic engineering and robotics, our approach to the development of plant factories should be minded on Practical Plant Factories considering our current farming practices and least capital needs rather than blindly employing the advanced technologies from developed countries. Thus, Korean plant factory development can be initiated with year round leaf vegetables production in NFT or DFT cultivation system instead of the moval bed system, in which aerial environment factors such as light, temperature, humidity and CO$_2$ concentration and root environment ones such as solution concentration, temperature, pH and water soluble oxygen shall be automatically controlled. And the seeding, seedling and transplanting operations shall be accomplished in the house entrance, and the harvesting and grading opreations shall be conducted in the house exit. For practical plant factories, environment control technologies including artificial light source, illumination and air conditioning, automatic management for nutrient solution and automatic production line of moval bed system, transplanting and harvest should be developed along with researches on the cost reduction of factory building construction.

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Effect of Cultural System and Sonic Strength of Nutrient Solution on the Growth of Dendrobium (Dendrobium phalaenopsis ) Seedlings (양액재배 시스템 및 양액농도가 덴파레(Dendrobium phalaenopsis) 유묘의 생장에 미치는 영향)

  • 정순주;이범선;안규빈
    • Journal of Bio-Environment Control
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    • v.6 no.4
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    • pp.284-291
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    • 1997
  • This study was conducted to evaluate the optimum hydroponic system and nutrient solution for shortening the early growth period and quality improvement of dendrobium ( Dendrobium Phalaenopsis) seedlings. Dendrobium seedlings with 3 to 4 leaves were transplanted in the deep flow technique(DFT) system, aeroponic system, and ebb and flow system with different concentration of balanced nutrient solutions recommended by the Japanese Horticultural Experiment Station. Growth characteristics of shoot and root were recorded and evaulated among treatments. For autumn cultivation, plant height was the longest at the DFT system with quarter concentration of nutrient solution, where aeroponic system with half concentration of nutrient solution. Aeroponic system stimulated the root growth but fresh weight was observed in the plots of DFT system. For spring cultivation, pH values increased up 7.5 at the DFT and aeroponic system, where EC values did not fluctuate regardless of cultural system. Ebb and flow system showed the best result in the growth of plant followed by BFT system and aeroponic system. Higher concentration of nutrient solution within this range of treatment was recommended for the growth promotion of leaf length and width in DFT system. In conclusion, growth responses differed depending on the cultural system, concentrations of nutrient solutions and duration of cltivation.

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Development of Drainage Water Disinfection System by Electric Shock in Recirculating Soilless Culture (순환식 수경재배에서 배액의 전기충격살균법 연구)

  • Lee, Mun Haeng;Kim, Sung Eun;Lee, Sang Don;Lee, Jae Eun;Kim, Hak Sun;Cho, Suk Keong;Sim, Sang Youn;Kim, Young Shik
    • Journal of Bio-Environment Control
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    • v.25 no.1
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    • pp.49-56
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    • 2016
  • This study was conducted to develop the disinfection system using electric shock for recycled nutrient solution in recycling soilless culture. Stainless steel (SUS 316) was found as the most appropriate electrode material for electrical disinfection system from the view of high electrical conductivity, low electric resistance, and low price. There were no changes in nutritional elements when the electric shock passed through the nutrient solution by stainless steel electrode. The amount of electric current increased with width than thickness of the electrode. The farther the distance between the electrodes was increased the time to reach out the aimed amount of current. The electric shock was applied to Ralstonia solanacearum and Fusarium oxysporum as representative bacteria and also fungi. Any of those pathogens were killed with the percentage of higher than 97% in the condition of 15VDC or 24VDC.

Effects of Subsurface Drip Irrigation and Aeration in Green Pepper Cultivation (시설풋고추 재배에서의 지중관수 및 공기주입 효과)

  • Kwon, Joon-Kook;Kang, Nam-Jun;Cho, Myeomg-Whan;Kang, Yun-Im;Park, Kyoung-Sub;Lee, Jae-Han
    • Journal of Bio-Environment Control
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    • v.18 no.3
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    • pp.225-231
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    • 2009
  • 'Nokkwang' green pepper plants were grown in soil system (silty loam with pH 6.5) under the greenhouse, to determine the effects of subsurface drip irrigation (SDI) and subsurface drip irrigation plus aeration (SDIA) into root zone comparing with conventional surface drip irrigation (DI) in terms of water use efficiency, soil properties, and growth and fruit yield. Two drip lines per crop row were layed on the soil surface in DI system, buried at a depth of 20cm below the soil surface in SDI system, and also buried at a depth of20cm below the soil surface and aerated for 3minutes a hour during the daytime ($08:00{\sim}19:00$) by a air compressor in SDIA system. A automatic irrigation with starting point of -20kPa and ending point of -10kPa based on soil moisture contents was applied by controllers and electronic vacum soil moisture sensors. Reduction in soil moisture contents was delayed in SDI and SDIA, compared to DI. Irrigation amount applied in pepper cultivation was around 30% less in SDI than in DI. Electric conductivity and nitrate nitrogen content in the surface soil grown green pepper were significantly lowered in SSDI and SDIA, compared to DI. Better development of root system was observed in SDIA and SDI than in DI. Results showed that pepper fruit yield increased by 30% in SDIA and 22% in SDI in comparision with DI.

Storage Quality of Sulhyang Strawberries as Affected by High O2 Atmosphere Packaging (고산소 환경기체조절 포장조건에 따른 설향 딸기의 저장 중 품질변화)

  • Lee, Hyun-Hee;Hong, Seok-In;Kim, Dongman
    • Korean Journal of Food Science and Technology
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    • v.45 no.2
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    • pp.191-198
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    • 2013
  • The storage quality of fresh Sulhyang strawberries packaged under modified atmospheres was investigated to examine the effect of high $O_2$ on the fruit. Fresh strawberries were packed into PP trays and top-sealed with PET/PP film. Initial gas compositions inside the packages were varied with air, 40% $O_2$/60% $N_2$, 60% $O_2$/40% $N_2$, and 80% $O_2$/20% $N_2$. Sealed packages in PE film bags with air and perforated PP trays were also used as another treatment and control, respectively. Quality attributes and viable cell counts of pathogenic bacteria were assessed during storage at $5^{\circ}C$ for 12 days. High $O_2$ concentration showed no significant effects on the physicochemical and microbial qualities of strawberries. Fruit packaged in PE film bags with 6-15% $O_2$ and 7-9% $CO_2$ during storage had the lowest viable cell counts of inherent microorganisms among the treatment samples. Growth of pathogenic bacteria was suppressed in perforated packages where molds occurred frequently. In an overall sensory aspect, the PE film packages exhibited higher scores than the others at the end of storage period. The experimental results suggested that gas-permeable film packaging with an appropriate combination of $O_2$ and $CO_2$ rather than gas-barrier tray packaging with an initially high $O_2$ concentration would be suitable for improving the storability of strawberries.

Fermentation Properties and Inflammatory Cytokines Modulating of Fermented Milk with Curcuma longa L Powder (강황을 첨가한 발효유의 발효특성과 면역조절 효과)

  • Gereltuya, Renchinkhand;Son, Ji Yoon;Magsar, Urgamal;Paik, Seung-Hee;Lee, Jo Yoon;Nam, Myoung Soo
    • Journal of Life Science
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    • v.25 no.1
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    • pp.75-83
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    • 2015
  • Curcuma longa L. (CL), a traditional medicinal plant, is well known as a functional food ingredient. The major component of CL is a curcumin of anthocyanin family that has multi-functions such as antimicrobial, anticancer, and antioxidant activity. In this study, fermented milk containing CL was prepared using a mixed strain culture (Bifidobacterium bifidus, Streptococcus thermophilus, Lactobacillus acidophilus), and its physicochemical properties were characterized. In addition, inflammatory cytokine-modulating effects of the fermented milk were also investigated. As regards the properties of fermented milk, the growth rate of lactic acid bacteria in fermented milk containing CL was found to be remarkably more rapid than control. During fermentation, caseins and whey proteins were observed to be partially hydrolyzed, and lactic acid and acetic acid were produced in larger amounts than in the control. The sensory score of fermented milk containing CL was lower than control, owing to its bitter taste and strong flavor. RAW 264.7 cells treated with CL fermented milk supernatant showed no cytotoxicity. Inflammatory cytokines such as tumor necrosis factor-alpha (TNF-${\alpha}$) and interleukin-6 (IL-6) were significantly produced by fermented milk with CL, compared to control. The secretion of nitric oxide (NO) from RAW 264.7 cells significantly increased relative to the control. Results from the present study suggested that CL could be used as a natural immunomodulating ingredient for making yogurts, beverages, and other products.

Multiple Shoot Induction on the New Cltivar, Saxifraga fortunei 'Greenstar' by Different Media and Plant Growth Rregulators (배지 및 생장조절제 종류를 이용한 바위떡풀 신품종 '그린스타' 의 다신초 유도)

  • Suh, Jong-Taek;Ryu, Seung-Yeol;Yoo, Dong-Lim;Nam, Chun-Woo;Hur, Youn-Young
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.2
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    • pp.83-86
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    • 2010
  • This study was conducted to develop in vitro propagation techniques of new cultivar, 'Greenstar', bred by Highland Agriculture Research Center. The multiple shoot induction and plant growth of in vitro plant were analyzed by MS media concentration (1/2 MS, 1 MS and 2 MS medium), plant growth regulators and its proper concentration; CPPU [Forchlorfenuron(N-(2-chloro-4-pridyl)-3-phenylurea) (0, 0.5, 1.0 and $2.0mg{\cdot}L^{-1}$), thidiazuron [(TDZ), (0.01, 0.1, 0.5 and $1.0mg{\cdot}L^{-1}$), zeatin (0, 0.5, 1.0 and $2.0mg{\cdot}L^{-1}$), and BA [6-benzylaminiopurine(BA), (0, 0.5, 1.0 and $2.0mg{\cdot}L^{-1}$)] in MS (3% sugar and 0.8% agar with pH 5.7) media. The highest number of induced shoots, leaves and roots were shown in 1/2 MS medium concentration. On the 1/2 MS medium, shoot numbers, shoot length, leaf numbers and root numbers were 11.0, 1.9 cm, 24.7, and 8.0, respectively. On the absence of CPPU in the 1/2 MS medium, shoot length and root numbers was greater than CPPU treatment, but the highest number of shoots was induced by the $2.0mg{\cdot}L^{-1}$ of CPPU concentration in 1/2MS medium. TDZ, zeatin, and BA treatments were not effective on the induction of multiple shoot in vitro culture. As a result, in vitro culture of new Saxifraga fortunei, 'Greenstar' with $2.0mg{\cdot}L^{-1}$ of CPPU in 1/2 MS medium was most effective for the rapid multiplication.

Comparison of Basal Physicochemical Changes of Reused Rockwool Substrate in Hydroponic Tomato Cultivation (수경재배 토마토 재사용 암면 배지의 기초 물리화학성 변화 비교)

  • Jae Seong Lee;Jong Hwa Shin
    • Journal of Bio-Environment Control
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    • v.33 no.2
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    • pp.114-119
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    • 2024
  • Rockwool substrate has superior physicochemical characteristics and is often used in crop cultivation. However, rockwool substrate has the disadvantages of high purchase cost and difficulty in disposal. Reuse of substrate can compensate for these disadvantages. Substrate must be disinfected and rehydrated during reuse, and various physicochemical changes during this process must also be considered. This study was to compare the physical properties of two types of rockwool substrates (reused and unused) and to evaluate the reuse potential of rockwool substrate by analyzing the chemical properties of the reused rockwool substrate during the rehydration process. The experiment on substrate physicochemical properties comparison was conducted from March to August 2023 using used rockwool substrates in tomato cultivation and unused rockwool substrates. Drainage time, drainage volume, and substrate weight were measured using load cells installed at the top and bottom of the irrigation monitoring system. The reused rockwool substrate weight and density were higher than those of the unused rockwool substrate, while the average drainage time after irrigation was 1.5 times longer for the reused rockwool than for the unused rockwool. The salinity concentration in different parts of the reused rockwool substrate was found to be lower in the reused rockwool substrate compared to the unused rockwool substrate. The electrical conductivity of the drainage was at its peak at the beginning of the drainage and decreased exponentially as the drainage volume increased. Change in electrical conductivity of the drainage over the irrigation time showed an exponential decay pattern. Through the experiments, the potential reusability of the rock wool substrate was assessed by conducting a comparative analysis of its physicochemical properties.