• Title/Summary/Keyword: pH 센서

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Multifunctional Marine Exploration Robot for Fish Farm Management (양식장 관리를 위한 다기능 해양탐사 로봇)

  • Yeo, Sang-Sam;Park, Joo-Ryeoll;Lee, Dong-Kyu;Kim, Myeong-Gi;Yu, Ju-Young;Lee, Sang Hyeop
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.07a
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    • pp.489-490
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    • 2021
  • 본 연구에서는 해양사고 처리 중 발생하는 인명사고 발생률을 감소시키고, 효율적으로 양식장을 관리하는 것을 전제로 카메라와 센서를 다기능 해양탐사 로봇에 적용하고자 한다. 현재의 양식장 관리 시스템은 수온 체크만 할 수 있게 되어있다. 이러한 시스템은 양식어에게 적합한 환경을 제공해주기 쉽지 않다. 본 논문은 이러한 문제점들을 개선하기 위해 기존의 해양 처리시스템과 양식 시스템 대신 카메라와 수온 센서, pH 농도 센서, 초음파 거리 센서, DC 모터, 블루투스 모듈을 적용한 다기능 해양탐사 로봇 기술을 제안한다. 기존의 시스템과는 다르게 안전하고 효율적으로 환경을 분석하고, 제어할 수 있다.

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Impact of pH on the response of bovine serum albumin to gold surface plasmon resonance chip (소 혈청 알부민의 금 표면 플라즈몬 공명 칩과의 반응에 대한 pH의 영향)

  • Sohn, Young-Soo
    • Journal of Sensor Science and Technology
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    • v.30 no.5
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    • pp.326-330
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    • 2021
  • Reactions between gold (Au) surface plasmon resonance (SPR) chips and bovine serum albumin (BSA) dissolved in solutions of different pH were investigated. The charge on the BSA depends on the pH of the solution in which it is dissolved. Thus, dissolving BSA in different pH solutions resulted in different charges of BSA. Among the BSA dissolved in solutions with pH 4.01, 7.4, and 10.01, the SPR response was the highest for BSA dissolved in the solution of pH 4.01. To eliminate the response variation owing to the difference in the refractive indices of the solutions, phosphate buffered saline (PBS) was injected into the system after the reaction of BSA with the Au SPR chip had happened. In this case too, the BSA dissolved in the solution with pH 4.01 exhibited the highest response. This may be attributed to the non-uniform distribution of ionic patches on the BSA, which can induce electrostatic attraction to the surface even though BSA has a positive charge at pH 4.01, and the absolute values of the net charge of BSA at pH 4.01 and 7.4 were very close.

InGaZnO Thin-Film Transistor-based pH Sensor with Parylene-C Gate Dielectric

  • Gwang-Eun Choi;Min-Joon Kim;Ra-Yeong Park;Yoon Kim;Dong-Wook Park
    • Journal of Sensor Science and Technology
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    • v.33 no.5
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    • pp.338-343
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    • 2024
  • The measurement of pH is of significant importance in chemistry, life sciences, and environmental monitoring. Unlike conventional pH sensors that utilize glass electrodes, thin-film transistor (TFT)-based pH sensors offer distinct advantages, including enhanced response speed and additional circuit functions. In this study, we developed a pH sensor that incorporates biocompatible parylene-C as both the substrate and sensing layer, thereby enhancing flexibility, transparency, and biological compatibility. We conducted tests to measure the voltage-current characteristics of the pH solutions and assessed their performance in terms of drift and hysteresis. Using InGaZnO (IGZO) as the channel material, our pH sensor demonstrated an average sensitivity of approximately 82 mV/pH, albeit with certain drift limitations. The initial pH measurements exhibited good reversibility over time. IGZO- and parylene-C-based TFT pH sensors are well suited for various applications, including wearable health monitoring, owing to their flexibility and biocompatibility.

Spectroscopic study on the development of fiber-optic pH sensor (광섬유 pH 센서 개발을 위한 분광학적 연구)

  • Yoo, Wook-Jae;Heo, Ji-Yeon;Cho, Dong-Hyun;Jang, Kyoung-Won;Seo, Jeong-Ki;Lee, Bong-Soo;Cho, Young-Ho;Moon, Joo-Hyun;Park, Byung-Gi
    • Journal of Sensor Science and Technology
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    • v.18 no.5
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    • pp.365-371
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    • 2009
  • In this study, we have fabricated a fiber-optic pH sensor which is composed of a light source, plastic optical fibers and a spectrometer. As an indicator, a phenol red is used, and a pH liquid solution is prepared by mixing of phenol red and various kinds of pH buffer solutions in these experiments. The emitting light from a light source is guided by plastic optical fibers to the pH liquid solution, and the optical characteristic of a light is changed in the pH liquid solution according to its color change. Therefore, we have measured the intensities and wavelength shifts of the modulated lights, which are changed due to the color variations of phenol red at different pH values, by using of a spectrometer for spectral analysis. Also, the relationships between the pH values of liquid solutions and the optical properties of modulated light according to the change of color of phenol red are obtained.

Effect of pH on Swelling Property of Hyaluronic Acid Hydrogels for Smart Drug Delivery Systems

  • Kim, Jin-Tae;Lee, Deuk-Yong;Kim, Young-Hun;Lee, In-Kyu;Song, Yo-Seung
    • Journal of Sensor Science and Technology
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    • v.21 no.4
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    • pp.256-262
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    • 2012
  • Hyaluronic acid(HA) hydrogels were synthesized by immersing HA microbeads in phosphate buffered saline solutions having different pH levels to assess the effect of pH on the swelling ratio of HA hydrogels for smart drug delivery systems. No beads were formed when the HA solution(below pH 9) was crosslinked with divinyl sulfone(DVS) because DVS is a basic solution. The variation regarding the size of the microbead was not significant, suggesting that the bead size is not a function of pH(10 ~ 14). However, the pore size of the microbeads decreased with increasing pH from 10 to 14, leading to the surface smoothness and dense network as a result of higher crosslinking. The swelling ratio of hydrogels increased when the pH rose from 2(acidic) to 6(neutral). Afterwards, it decreased with further increasing pH(basic). The lower swelling ratio may be due to the lack of ionization of the carboxyl groups. On the other hand, a higher swelling ratio is likely due to the increased electrostatic repulsions between negatively charged carboxyl groups on different chains. Experimental results suggested that pH-responsive HA hydrogels can be applicable to the controlled drug delivery systems.

ISFET Urea Sensor Using PVA-SbQ Polymer (PVA-SbQ 고분자 물질을 이용한 ISFET 尿素센서)

  • Sung Moon Choi;Chang-Soo Kim;Dong-Hyun Nam;Byung-Ki Sohn;Ui-Rak Kim
    • Journal of the Korean Chemical Society
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    • v.36 no.4
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    • pp.496-503
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    • 1992
  • An ISFET urea sensor was fabricated by immobilizing the urease using photosensitive polymer, poly(vinyl alcohol)-SbQ on the H$^+$ sensing $Si_3$$N_4$ thin film of pH-ISFET. The sensor could determine the urea concentration in the range of 1∼50 mg/dl with fast response and good repeatability. For its application to clinical analysis, the interferences of the various materials which cause inhibition in urease catalytic reactions in blood was investigated. The results of the urea measurements in blood plasma using the ISFET urea sensor were compared with these of conventional spectrophotometric method.

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pH Measurements with a Microcantilever Array-Based Biosensor System

  • Hur, Shin;Jung, Young-Do
    • Journal of Sensor Science and Technology
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    • v.21 no.3
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    • pp.186-191
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    • 2012
  • In this paper, we present a pH measurement method that uses a microcantilever-array-based biosensor system. It is composed of microcantilever array, liquid cell, micro syringe pump, laser diode array, position sensitive detector, data acquisition device, and data processing software. Four microcantilevers are functionalized with pH-sensitive MHA(mercaptohexadecanoic acid) as a probe, while three microcantilevers are functionalized with HDT(hexadecane thiol) as reference. We prepare PBS(phosphate buffered saline) solutions of different pH and inject them into the liquid cell with a predefined volumetric speed at regular time intervals. The functionalized mircocantilevers in the liquid cell deflect as a self-assembled monolayer on the microcantilever binds with probe molecules in the solution. The difference in deflection between the MHA-covered probe microcantilever and the HDT-covered reference microcantilever was used to compensate for thermal drift. The deflection difference clearly increases with increasing pH in the solution. It was shown that when the pH values of the PBS solutions are high, there were large variations in the deflection of microcantilevers, whereas there were small variations for low pH value. The experimental results show that the microcantilever array functionalized with MHA and HDT can detect pH value with good repeatability.

The Fabrication of FET-Type Reference Electrode Using Ion-Blocking Membrane of Polymer Double Layer (고분자 이중층의 이온 방해막을 이용한 FET형 기준전극 제작)

  • Lee, Young-Chul;Kim, Young-Jin;Jeong, Hun;Kwon, Dae-Hyuk;Sohn, Byung-Ki
    • Journal of Sensor Science and Technology
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    • v.9 no.2
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    • pp.106-112
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    • 2000
  • A FET-type reference electrode(REFET) is an effective method to eliminate typical problems with ISFET(ion sensitive field-effect transistor) such as drift, temperature, light-dependence and miniaturization of reference electrode. However, it is difficult to make the highly reliable REFET with excellent long-term stability and reproducibility. In this paper, an ion-blocking membrane was applied to the REFET for the PET-type electrolyte sensors(pH, pNa-ISFET). The fabricated REFET indicated the stable sensitivity (55.4 mV/pH, 53.5 mV/decade) and good linearity in the pH and pNa measurement. In the measurement, ISFET/Pt/REFET configuration showed excellent stability and reproducibility.

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pH-Drift Characteristics of Sol-Gel-Deposited $Ta_{2}O_{5}$-Gate ISFET (Sol-Gel 법으로 형성한 $Ta_{2}O_{5}$ 게이트 ISFET의 pH 드리프트 특성)

  • Kwon, Dae-Hyuk;Cho, Byung-Woog;Kim, Chang-Soo;Sohn, Byung-Ki
    • Journal of Sensor Science and Technology
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    • v.5 no.2
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    • pp.15-20
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    • 1996
  • The diffusion of hydrogen ions into a sensing membrane causes the output voltage of pH-ISFET to vary with time, which might be considered to be drift in this sensor. We tried to deposit ultra-thin film for minimizing tile drift that has been considered to be main obstacle for putting pH-ISFET to practical use. In this paper, tantalum pentoxide, known as a good pH sensing membrane, was formed to about $70{\AA}$ thick by sol-gel method on $Si_{3}N_{4}/SiO_{2}$-gate of pH-ISFET. The fabricated $Ta_{2}O_{5}$-gate pH-ISFET showed good sensitivity(about 59mV/ pH) and good lineality in the range of pH $3{\sim}11$, and had relatively small average pH drift of about 0.06 pH/day.

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