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A Study on the Improvement of Information Security Model for Precision Medicine Hospital Information System(P-HIS) (정밀의료 병원정보시스템(P-HIS) 정보보호모델 개선 방안에 관한 연구)

  • Dong-Won Kim
    • Convergence Security Journal
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    • v.23 no.1
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    • pp.79-87
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    • 2023
  • Precision Medicine, which utilizes personal health information, genetic information, clinical information, etc., is growing as the next-generation medical industry. In Korea, medical institutions and information communication companies have coll aborated to provide cloud-based Precision Medicine Hospital Information Systems (P-HIS) to about 90 primary medical ins titutions over the past five years, and plan to continue promoting and expanding it to primary and secondary medical insti tutions for the next four years. Precision medicine is directly related to human health and life, making information protecti on and healthcare information protection very important. Therefore, this paper analyzes the preliminary research on inform ation protection models that can be utilized in cloud-based Precision Medicine Hospital Information Systems and ultimately proposes research on ways to improve information protection in P-HIS.

Antibacterial Efficacy of Dental Sealant Containing Phytoncide

  • Song-Yi Yang;Myung-Jin Lee
    • Journal of dental hygiene science
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    • v.23 no.4
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    • pp.389-395
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    • 2023
  • Background: Dental caries prevention is a key research focus in dentistry, requiring advancements in the formulation of dental sealants. This study investigated the physical and antibacterial attributes of dental sealant enriched with phytoncide. Methods: Phytoncide was mixed with a commercially available dental sealant (Clinpro) at concentrations of 0 (control), 1.5%, 3%, and 4.5% by weight (wt%). The flexural strength, curing depth, and wettability of the dental sealant were measured. Antibacterial properties against Streptococcus mutans were evaluated through the enumeration of colony-forming units. Statistical analyses employed one-way variance analysis followed by Tukey's test (p<0.05). Results: The dental sealant containing 3% phytoncide showed no significant difference in flexural strength and curing depth compared with that in the control group (p>0.05). The flexural strength and curing depth decreased with increasing phytoncide content and significantly differed in sealant containing 4.5 wt% phytoncide (p<0.05). Wettability did not differ between the experimental and control groups (p>0.05). The antibacterial properties of the sealant containing 1.5% phytoncide were the same as those of the control group (p>0.05). The bacterial viability was significantly reduced in groups containing 3% and 4.5% phytoncide compared with that in the control group (p<0.05). Conclusion: Dental sealants incorporating phytoncide have a promising potential as antibacterial dental materials.

Exploring the Strategy for Acquiring ISMS Certification through Probit Regression: Focusing on Organizational Characteristics (Probit 회귀분석을 통한 ISMS 인증 취득 전략 탐색: 조직 특성을 중심으로)

  • SunJoo Kim;Tae-Sung Kim
    • Journal of Information Technology Services
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    • v.23 no.1
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    • pp.11-25
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    • 2024
  • In the field of information security management systems, one of the representative certifications in Korea is ISMS-P certification, and internationally, ISO/IEC 27001 certification is recognized. When companies acquire both ISMS-P (or ISMS) and ISO/IEC 27001 certifications, budget and manpower are duplicated in similar areas. Therefore, it is necessary for the company to choose and invest in a certification that is suitable for its conditions. This paper proposes a strategy for obtaining information security management system certification that is suitable for the characteristics of the company, allowing for effective information security management based on the company's conditions. To achieve this, data were collected from the Ministry of Science and ICT's Information Security Disclosure System (ISDS), the Korea Internet & Security Agency (KISA), and the Financial Supervisory Service's Data Analysis, Retrieval and Transfer System (DART), and Probit regression analysis was conducted. During the Probit regression analysis, the relationships between seven independent variables and five cases of ISMS-P (or ISMS) acquisition, ISMS-P acquisition, ISMS acquisition, ISO/IEC 27001 acquisition, and both ISMS-P (or ISMS) and ISO/IEC 27001 acquisition were analyzed. The analysis results revealed the relationship between company characteristics, including industry, and certification acquisition in the ISMS field. Through this, strategies for certification acquisition based on company types could be suggested.

Cellulase를 생산하는 Bacillus sp. 79-23 분리와 효소 생산성

  • 윤기홍;정경화;박승환
    • Microbiology and Biotechnology Letters
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    • v.25 no.6
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    • pp.546-551
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    • 1997
  • A bacterium producing the extracellular cellulases was isolated from soil and has been identified as Bacillus sp. The isolate, named Bacillus sp. 79-23, was shown to be very similar to B. subtilis on the basis of its biochemical properties. The carboxymethyl cellulase (CMCase) of culture supernatant was most active at 60$\circ$C and pH 6.0, and retained 90% of its maximum activity at pH 7.0. The additional carbon sources affected the CMCase productivity than nitrogen sources in the culture medium. The carbon sources including wheat bran, rice straw, maltose and glucose increased the enzyme productivty. Especially, the maximum CMCase production was 5.2 units/ml in LB medium supplemented with 3% (w/v) wheat bran, which was 13-folds more than that in LB medium. It was found that the enzyme production was in association with the growth of Bacillius sp. 79-23. But, whean bran did not affect the growth of isolate, suggesting that increasement of CMCase production was owing to the induction of CMCase biosynthesis by wheat bran. In addition, both water-soluble and insoluble components of wheat bran was involved in induction of CMCase biosynthesis.

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Factors Influencing on Cancer Stage of Women Patients with Colon Cancer (여성 결장암 환자의 암 진전도에 영향을 미치는 요인)

  • Lee, Seong-Ran
    • Proceedings of the KAIS Fall Conference
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    • 2012.05a
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    • pp.336-339
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    • 2012
  • 본 연구는 여성 결장암 환자의 암 진전도에 영향을 미치는 요인을 규명하고자 시도하였다. 자료수집은 2012년 1월 23일부터 2012년 2월 23일까지 서울에 소재한 종합병원 외과에 내원한 결장암 환자 227명을 선정하여 설문조사를 하였다. 연구결과는 첫째, 이전의 결장암 검사여부는 암 검사를 하지 않은 여성은 distant는 61.7%로 localized인 여성은 36.7% 보다 유의하게 높았다($X^2$=26.41, p<.05). 둘째, 교육과 암검진력은 양의 상관관계를 보였다(r=0.27, p<.01). 셋째, 연령이 암 진전도를 23.8%, 과거 결장암 검진여부는 7.5%, 스트레스여부는 4.1%로 각각 설명하였다. 이러한 결과를 토대로 결장암 위험요인에 노출되어 있는 여성들의 결장암 발생을 예방하기 위해서는 조기검진에 대한 적극적인 홍보과 교육이 필요하다고 본다.

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Interactions of Membrane and PMAP-23 Studied by $^{31}P$ solid-state NMR Spectroscopy

  • Kim, Si-Won;Kim, Suhk-Mann
    • Journal of the Korean Magnetic Resonance Society
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    • v.11 no.2
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    • pp.110-114
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    • 2007
  • [ $^{31}P$ ] powder pattern spectra were measured to investigate the aspects of the interaction between the MLV (Multilamellar vesicle) and PMAP-23, a membrane of cathelicidin family and then CSAs(chemical shift anisotropy) were calculated to indentify the extent of perturbation of phospholipid mobility by the peptides. We found that acidic phospholipid interacts strongly with PMAP-23, and the analogues which modified to increase the amphipathic property showed that larger change of CSA. The analogue which introduced positive charge showed the same effects with amphipathic property.

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Advanced Wastewater Treatment Using Anoxic-Aerobic Reactor Filled with Porous Media (다공성 미디어를 충진한 혐기-호기 반응조를 이용한 하수고도처리에 관한 연구)

  • Kim, Dong-Ha
    • Journal of Korean Society of Water and Wastewater
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    • v.21 no.1
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    • pp.83-89
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    • 2007
  • A biological anoxic-aerobic reactor filled with porous media was operated in lab scale for the advanced wastewater treatment. The experiments were conducted for 6 months with three HRTs (4, 6, 8hr) and temperature of $23{\sim}25^{\circ}C$. Some other experimental conditions were as follows; nitrification reactor (MLSS 4,500mg/L, DO 3.3mg/L, $23{\sim}28^{\circ}C$), denitrification reactor(MLSS 8,000mg/L, ORP -100mV, Temp.$19{\sim}23^{\circ}C$). Average removal efficiencies of SS, $BOD_5$, $COD_{Cr}$, T-N, and T-P were 97.8%, 95.5%, 94.5%, 80.2%, and 60.6%, respectively. The reactor filled with porosity media showed stable removal capacity for organics and nutrients. Fast and complete nitrification and denitrification were accomplished. Maintaining high MLSS with porous media in the nitrification and denitrification reactor appears to enhance the nitrogen removal process. For the higher T-P removal, some coagulant addition process will be needed.

Three Point Bending Fatigue Property with Heat Treatment Condition in a Powder Metallurgical High Speed Steel JYPS-23 (분말고속도공구강 JYPS-23에서 열처리조건에 따른 3점 굽힘피로특성)

  • 홍성현;배종수;김용진
    • Journal of Powder Materials
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    • v.7 no.3
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    • pp.131-136
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    • 2000
  • The effect of tempering temperature on the three point bending fatigue behavior of a P/M high speed steel JYPS-23 (1.28% C, 4.20% Cr, 6.40% W, 5.00% Mo, 3.10% V, bal. Fe) was investigated. The number of cycles to failure of the specimen austenitized at $1175^{\circ}C$ drastically increased with increasing tempering temperature. As tempering temperature increased from 500 to $620^{\circ}C$, the volume fraction and average size of carbides (MC or M6C) did not significantly changed, while hardness decreased drastically. The reduced hardness is due to the softening of matrix, which increased the resistance of the fatigue crack propagation. For a practical application, powder compacting test were also conducted with the P/M high speed steel punches tempered at 500, 580, and $620^{\circ}C$. The number of compacting cycles to failure of the punches also increased with increasing tempering temperature.

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Comparison of Expectation and Satisfaction of Implant Patients in Pre-post Implant Therapy (임플란트 시술환자 시술 전·후의 기대와 만족도 비교)

  • Han, Ji-Hyoung;Kim, Ki-Eun
    • Journal of dental hygiene science
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    • v.11 no.2
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    • pp.121-127
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    • 2011
  • This study was conducted to improve patients satisfaction by comparing patients expectation prior to the implant therapy to patient satisfaction after the implant therapy. The data of 158 patients with dental implant in Seoul, Gyeonggi-Do and Cheonan city was obtained. The results are as follows : 1. 40.5% of patients placed one implant and 36.1 % of patients answered that the average cost for each implant is from 1,500,000 to 2,000,000won. 23.4% of them answered they decided to have implant because no tooth preparation is required. 2. Overall, the expectation level for implant therapy in general properties, women showed higher level of expectation than men. Especially, 'Implant has a longer life than other denture' showed significant difference between women(4.29) and men(3.87). Expectation by age, 'Implant has similar color and shape' was found the highest in age 20(4.38). Satisfaction by general properties, 'No tooth preparation required' was found the highest in age 20(4.57) and was statistically significant(p<.002). 3. Comparing patients' expectation prior to implant therapy to satisfaction afterward, 'Implant prevents jawbone resorption and keeps facial appearance' showed 3.7 of expectation but satisfaction was found increased to 3.87(p=.020). No tooth preparation required' was found 3.95 in expectation prior to implant therapy but after therapy it was found 4.23 in satisfaction (p<.001). 4. Overall satisfaction in implant therapy was found 4.25, recommendation to other patients was found 4.18 and repurchase was found 4.17.

The Effect of cutaneous Stimulation and Distraction on IV Injection Pain of Chemotherapy Patients (피부자극과 관심전환이 항암제 정맥주사 삽입시 통증감소에 미치는 영향)

  • 박정숙
    • Journal of Korean Academy of Nursing
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    • v.28 no.2
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    • pp.303-318
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    • 1998
  • Cutaneous stimulation and distraction are independent nursing interventions used in various painful conditions, which is explained by gate control theory. This study was aimed at identifying the effect of cutaneous stimulation, distraction and combination of cutaneous stimulation and distraction on the reduction of intravenous injection pain levels of chemotherapy patients. Repeated measurement post test research design was used for one group. Fifty-three cancer patients who received intravenous chemotherapy regulary in outpatient injection rooms of D medical center and Y medical center in Taegu were studied from June 23, 1997 to July 12, 1997. First the intravenous injection pain level of the control period was measured. Second, the intravenous injection pain level of the experimental period using cutaneous stimulation was measured. Third, the intravenous injection pain level of the experimental period using distraction was messured. Fourth, the intravenous injection pain level of the experimental period using a combination of cutaneous stimulation and distraction was measured. The instruments used for this study were a visual analogue pain scale as subjective pain measurement and an objective pain behavior checklist. Analysis of data was done by use of repeated measure ANOVA, bonferni, t-test, and F-test. The results of this study were summerized as follows : 1) The first hypothesis that the subjective pain score of intraveneous injection pain in the experimental period with cutaneous stimulation will be lower than in the control period was rejected. 2) The second hypothesis that the objective pain behavior score of intravenous injection pain in the experimental period with cutaneous stimulation will be lower than in the control period was accepted(F=24.23, p=0.0001, Bornferni p<.05). 3) The third hypothesis that the subjective pain score of intraveneous injection pain in the experimental period with distraction will be lower than in the control period was rejected. 4) The fourth hypothesis that the objective pain score of intravenous injection pain in the experimental period with distraction will be lower than in the control period was accepted(F=24.23, p=0.0001, Bornferni p<.05). 5) The fifth hypothesis that the subjective pain score of intravenous injection pain in the experimental period with combination of cutaneous stimulation and distraction will be lower than in the control period was accepted(F=3.04, p=0.031, Bonferni p<.05). 6) The sixth hypothesis that the objective pain score of intravenous injection pain in the experimental period with combination of cutaneous stimulation and distraction will be lower than in the control period was accepted(F=24.23, p=0.0001, Bonferni p<.05).

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