• Title/Summary/Keyword: p-persistent

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Influencing Factors on Performance for Standard Precaution of Healthcare Workers of General Hospital for Infection Control (종합병원 의료종사자의 감염관리 표준주의 수행도 영향요인)

  • Oh, Ji Eun;Park, Ju Young
    • Journal of Digital Convergence
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    • v.16 no.4
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    • pp.231-249
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    • 2018
  • The purpose of this study is analyze the factors affecting the standard precaution(SP) performance on the knowledge, awareness, attitude and safety environment for SP of healthcare workers of general hospitals. The research method was a descriptive research study. The subject were 262 of healthcare workers of general hospitals. The data were analyzed using descriptive statistics, t-test, Chi-square test, ANOVA, Person's correlation coefficient and Multiple regression analysis using the SPSS program. As a result of the correlation analysis SP Performance was positively correlated with attitude (r=.18, p=.003), safety environment (r=.42, p<.001) and awareness (r=.63, p<.001). As a result of the stepwise multiple regression analysis on the factors influencing SP performance were SP awareness and safety environment. Therefore, in order to improved performance of SP, it's important to improve a awareness and safety environment of SP. Different and persistent infection management educational programs that consider the occupational characteristics and monitoring are required.

Anlysis of Fatigue Perceived by the Hospitalized Children's Mother (입원 환아의 어머니가 자각하는 피로)

  • Park In-Sook;Kim Shin-Jeong;Kang Kyung-Ah;Kim Tae-Hee
    • Child Health Nursing Research
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    • v.10 no.1
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    • pp.80-88
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    • 2004
  • Purpose: The purpose of this study was to explore the fatigue of the mothers of the hospitalized children's mothers in descriptive study. Method: Two hundred eighty three mothers who take care of the hospitalized children in three University hospitals were enrolled from June, 1 to October, 30, 2003. Data were collected using a questionnaire titled 'Symptom Table on Fatigue Perception' designed by the Fatigue Research Committee of Japan, consisted of a total 30 items categorized into three sub-dimensions: the physical, the psychological and the neuro-sensory. SPSS was used for the analysis of data with 0.05 of significance. Result: 1) The mean average fatigue score of subjects was 1.94(SD:.48): the physical fatigue revealed the highest value with a mean of 2.19(SD:.57), followed by psychological fatigue with a mean score of 1.85(SD:.52), neuro-sensory fatigue with a mean of 1.79(SD:.51). 2) With the respect to the general characteristics of hospitalized children and mothers, there were statistically significant differences in the mothers' fatigue perception by the child sex(t=-2.697, p=.008), the character of child(F=9.032, p=.000), the child condition compared to pre-hospitalization(F=3.523, p=.031), with or without support in domestic households(t=-1.981, p=.049), the amount of sleeping time(t=2.704, p=.007), and with or without of night-time sleep disturbance because of the child hospitalization(t=2.082, p=.038). Conclusion: These results suggest that health care professional need to be aware of the persistent presence of the maternal fatigue related to the child hospitalization and the factors worsen the degree of the fatigue.

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Identification of Atherosclerosis Related Gene Expression Profiles by Treatment of Benzo(a)pyrene in Human Umbilical Vein Endothelial Cells

  • Lee, Sun-Hee;Lee, Seung-Eun;Ahn, Hyun-Jong;Park, Cheung-Seog;Cho, Jeong-Je;Park, Yong-Seek
    • Molecular & Cellular Toxicology
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    • v.5 no.2
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    • pp.113-119
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    • 2009
  • Benzo(a)pyrene (BaP) is a persistent environmental contaminant and is present in tobacco smoke. BaP is considered a major contributor of cardiovascular disease. While the activation of endothelial cells by stimuli including tobacco smoke and air pollution contributes importantly to cardiovascular disease, the nature of BaP's mechanism is unclear. In this study, gene expression profiles were investigated in BaPtreated human umbilical vein endothelial cells (HUVECs). Various atherosclerosis related genes could be up- and down-regulated more than 2-fold by BaP, and mRNA levels of atherosclerosis related genes encoding apolipoproteinC III, TLR 2, ICAM 1 and exportin 4 were significantly increased by BaP. Our data suggest that BaP-mediated changes in gene expression contribute to the progression of cardiovascular disease.

Effect of Oxygenation of Cardioplegic Solution on Electrical Stability and Postischemic Recovery of Cardiac Function after Ischemic Arrest in Isolated Rat Heart[ I ] (백서의 적출된 심장에서 심정지액의 산소화가 허혈성 심정지후 심기능 회복에 미치는 영향[I])

  • 윤재도
    • Journal of Chest Surgery
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    • v.25 no.2
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    • pp.125-130
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    • 1992
  • To evaluate the effect of oxygenation[95% O2+5% CO2] of St. Thomas Hospital No.2 cardioplegic solution[Plegisol], 20 isolated perfused rat hearts were studied under hyp-othermic[20oC] ischemic arrest for 2 hours with infusion of cardioplegic solution every 30 minutes throughout the ischemic period. Ten isolated hearts were studied with the oxygenated cardioplegic solution and 10 another isolated hearts with the nonoxygenated one. Mean oxygen tensions of the nonoxygenated and oxygenated cardioplegic solutions were 150mmHg and 470mmHg, respectively. Two in 10 hearts infused with the nonaxygenated cardioplegic solution were not recovered from nonworking heart due to persistent ventricular fibrillation. In comparing hem-odynamic parameters between both groups, the mean postischemic recovery[expressed as a percentage of its preischemic control value] was significantly greater with the oxygenated solution[in 10 recovered hearts] than the nonoxygenated solution[in 8 recovered hearts] [95.9$\pm$1.8% compared with 88.5$\pm$2.9% in peak aortic pressure, p<0.05, 75.7$\pm$5.2% compared with 43.5$\pm$6.5% in aortic flow, p<0.01, 75.5$\pm$4.6% compared with 54.1$\pm$5.6% in cardiac output, p<0.01, 78.3$\pm$4.6% compared with 60.3$\pm$4.6% compared with 60.3$\pm$6.2% in stroke volume, p<0.05, and 80.4$\pm$5.3% compared with 58.6$\pm$7.0% in dP/dT, p<0.05]. It is concluded that oxygenation of St. Thomas Hospital No.2 cardioplegic solution improves cardiac electrical stability and postischemic hemodynamic recovery after ischemic arrest in the isolated perfused rat heart.

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Hematological and Serum Chemical Findings following Repeated Medication of Diminazene Aceturate in Canine Babesiosis (만성 Babesia 감염견에서의 Diminazene Aceturate의 반복투여에 따른 혈액학 및 혈액화학적 변화)

  • 황미정;이희석;이근우
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.349-358
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    • 2000
  • Effects of repeated administration of diminazene aceturate (Hoechst Veterin r GmbH. Ger- many) that has been introduced as effective compound against Babesiosis and trppanosomiasis were investigated in dogs experimentally infacted with Babesia gibsoni. Adull mongrel dogs of both sexes were inoculated will nonpreserved infected blood and then maintained chronic anemia. A single dose of diminazene aceturate of 7mg/kg b.w. was administrated intramnuscularIy on day 7.1 arid ,7. Clin- ical and hcmatological findings following inoculation and medication were observed and 7enlm bio chemical analysis also was monitored. Parasitemia was detected between 3 and 6 days after inoculation. The rate of parasitized erythrocytes,1 in peripheral blood reached the peak on the 13th day and was maintained the percentage of 0.1 to 1.0 until the medication of diminazene aceturate. RBC was significantly (p<0.01) decreased on the 3rd day and then kept on decreasing. The lowest value was observed on the 16th day. WBC remained generally within normal ranges. PCV revea1ed the sig-nificant (p<0.01) decrease within the range of 24-27% and platelet was significantly (p<0.05) decreased during the period. Senum chemical values (ALT, AST. total bilirubin. LDH BUN, area- tinine, total protein. albumin and glucose) were within normal ranges during the experimental period. Serum CPK values were significantly (p<0.01) increased on the 3rd day. There was no clinically, sig-nificant difference in a single dose of diminazene aceturate of 7 mg/kg b.w. But the administration of diminazene aceturate of 14 mg/kg b.w. revealed vomiting and anorexia and one dog died in 30 hours after administration. The administration of 14mg/kg b.w. resulted in vomiting, salivation, actor- exia, tremor of head and involuntary movement and one dog died in 27 hours after administration. WBC, RBC, PCV and Platelet values were no significant difference and hematological findings revealed persistent anemia and thrombocytopenia during chronic anemia after inoculation. AST activity its was significantly (p<0.01) increased 11\\`from 3 days after medication and AST activity was on the same trend. Serum CPK activity revealed significant (p<0.01) increase within 6 hors)\\`s after every administration and decreased in 48 howl·s after administration.

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Hapten Synthesis and Influence of Coating Ligands on Enzyme-linked Immunoreaction of DDT

  • Hong, Ji- Youn;Kim, Jong-Hyun;Choi, Myung-Ja
    • Bulletin of the Korean Chemical Society
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    • v.23 no.10
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    • pp.1413-1431
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    • 2002
  • For the development of immunodetection method of 4,4'-dichlorodipheny-2,2,2-trichloroethane (p,p'-DDT), a persistent and broad toxic organochlorine insecticide, various DDT derivatives were synthesized and characterized for the use of immunogens and the coating ligands for the antibody evaluation. The appropriate lengths of linkers were introduced to investigate more efficient DDT derivatives. Among these hapten derivatives, 2,2-Bis(4-chlorophenyl)acetic acid (DDA), 5,5-Bis(4-chlorophenyl)-5-hydroxypentanoic acid (DDHP) and 5,5-Bis(4-chlorophenyl)-5-chloropentanoic acid (DDCP) were conjugated with keyhole limpet hemocyanin (KLH) for the use of immunogen to produce antibodies. 6,6-Bis(4-chlorophenyl)-6-hydroxyhexanoic acid (DDHH) and 3-[6,6-Bis(4-chlorophenyl)-6-hydroxyhexanoylamino]propanoic acid (DDHHAP) in addition to above hapten derivatives were conjugated to ovualbumin (OVA) and bovine serum albumin (BSA) for the use of coating ligands to measure the titration level of antibody and the displacement of free analytes. Three matching pairs of antibodies and coating ligands were selected for the simultaneous detection of p,p'-DDT and its related compounds of DDA and 2,2-bis(4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE) by investingating the displacement of free analytes in an indirect ELISA. These were PAb #1 and coating ligand DDCP-OVA, PAb #1 and DDHHAP-OVA, and PAb #3 and DDHHAP-OVA. The most useful immunoreaction for DDT analytes were obtained using PAb #3 and coating ligand DDHHAP-OVA showing 3.4 ng/mL of lower limit of detection. These results indicated that titration level and free analytes displacement were greatly influenced by hapten derivatized and carrier proteins conjugated.

Efficient Elimination of Tetracycline by Ferrate (VI): Real Water Implications

  • Levia Lalthazuala;Lalhmunsiama Lalhmunsiama;Ngainunsiami Ngainunsiami;Diwakar Tiwari;Seung Mok Lee;Suk Soon Choi
    • Applied Chemistry for Engineering
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    • v.34 no.3
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    • pp.318-325
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    • 2023
  • The detection of antibiotics in treated wastewater is a global concern as it enters water bodies and causes the development of antibiotic resistance genes in humans and marine life. The study specifically aims to explore the potential of ferrate (VI) in eliminating tetracycline (TCL). The degradation of TCL is optimized with parametric studies, viz., the effect of pH and concentration, which provide insights into TCL elimination. The increase in pH (from 7.0 to 10.0) favors the percentage removal of TCL; however, the increase in TCL concentrations from 0.02 to 0.3 mmol/L caused a decrease in percentage TCL removal from 97.4 to 29.1%, respectively, at pH 10.0. The time-dependent elimination of TCL using ferrate (VI) followed pseudosecond-order rate kinetics, and an apparent rate constant (kapp) was found at 1978.8 L2 /mol2 /min. Coexisting ions, i.e., NaNO3, Na2HPO4, NaCl, and oxalic acid, negligibly affect the oxidation of TCL by ferrate (VI). However, EDTA and glycine significantly inhibited the elimination of TCL using ferrate (VI). The mineralization of TCL using ferrate (VI) was favored at higher pH, and it increased from 18.57 to 32.52% when the solution pH increased from pH 7.0 to 10.0. Additionally, the real water samples containing a relatively high level of inorganic carbon spiked with TCL revealed that ferrate (VI) performance in the removal of TCL was unaffected, which further inferred the potential of ferrate (VI) in real implications.

A study on Anaerobic Biodegradation of Dichlorophenol (Dichlorophenol의 혐기성 분해에 관한 연구)

  • Park, Ju Seuk;Jeon, Yeon Ho
    • Journal of Korean Society of Water and Wastewater
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    • v.9 no.2
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    • pp.127-135
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    • 1995
  • The purpose of this study was to more fully evaluate the potential for chlorophenol degradation in anaerobic sludge. The pH effects on the ring cleavage of phenol and dechlorination of monochlorophenol isomers and dichlorophenl isomers. This study results are as follows ; Each of the monochlorophenol isomers were degraded in anaerobic sludge. The relatives rates were 2-Chlorophenol > 3-Chlorophenol > 4-Chlorophenol. Biodegradation results for the dichlorophenol isomers in anaerobic sludge are such as 2,3-dichlorophenol and 2,5-dichlorophenol was reductively dechlorinated to 3-chlorophenol, 2,4-dichlorophenol to 4-chlorophenol, 2,6-dichlorophenol to 2-chlorophenol. The two dichlorophenol isomers which did not contain an ortho Cl substituent 3,4-dichlorophenol and 3,5-dichlorophenol were persistent during the 6-week incubation. The rate of dechlorination was enhanced by the presence of a Cl group ortho, rather than para, to the site of dechlorination.

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A MAC Protocol Using Delay Information Feedback for High-Speed MAN (지연정보 되먹임을 이용하는 고속 MAN용 MAC 프로토콜)

  • 김성원;정동근;최종호
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.29B no.5
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    • pp.21-29
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    • 1992
  • This paper proposes a new MAC propocol for high-speed MAN. The proposed protocol is based on the P$_1$-persistent tranmission scheme and each node calculates the transmission probability periodically by using delay information(DI). A window mechanism for the calculation of message delay in each node is proposed to improve the adaptability of the proposed protocol to traffic changes. The capactiy of the proposed protocol is analyzed. The simulation results show that the proposed protocol gives fair message delay under heavy load conditions and, when the transmission speed or distance is increased, the message delay variation of the proposed protocol is less than that of IEEE 802.6 DQDB.

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Subsidence Due to Groundwater Withdrawal in Kathmandu Basin Detected by Time-series PS-InSAR Analysis

  • Krishnan, P.V.Suresh;Kim, Duk-jin
    • Korean Journal of Remote Sensing
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    • v.34 no.4
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    • pp.703-708
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    • 2018
  • In recent years, subsidence due to excessive groundwater withdrawal is a major problem in the Kathmandu Basin. In addition, on 25 April 2015, the basin experienced large crustal displacements caused by Mw 7.8 Gorkha earthquake. In this study, we applied StaMPS- Persistent Scatterer InSAR (StaMPS PS-InSAR) technique to estimate the spatio-temporal displacements in the basin after the mainshock. 34 Sentinel-1 C-band SAR data are used for measuring subsidence velocity during 2015-2017. We found the maximum subsidence velocity of about 9.02 cm/year and mean subsidence rate of about 8.06 cm/year in the line of sight direction, respectively, in the central part of the basin.