• 한국토양비료학회지
• /
• 제29권3호
• /
• pp.275-281
• /
• 1996

정수장슬러지를 건물중 기준으로 10a당 0, 1, 3, 5톤의 비율로 토양에 시용한 후. 대두 및 당근에 대한 몇가지 화학성분의 흡수와 수량을 조사한 결과는 다음과 같다. 1. 정수장슬러지의 화학적 특성상 pH, OM 및 CEC면에서 미미하나마 농업적인 이익을 기대할 수 있을 것으로 판단된다. 2. 슬러지 시용은 토양중 유기물과 CEC 수준을 다소 증가시켰다. 3. 10a당 1톤과 같은 낮은 수준의 슬러지 시용량은 대조구에 비해 대두의 수량을 증가시킨 반면, 계속적인 시용량의 증가는 역으로 대두의 수량을 감소시켰다. 그러나 당근의 지하부는 슬러지의 시용량이 증가할수록 높은 수량효과가 인정되었다. 4. 대두 및 당근의 두 작물에서 공히 슬러지 시용량의 증가로 인산의 흡수억제가 관찰된 반면에 슬러지의 시용이 작물에 대한 Al의 흡수를 증가시키지는 않았다. 5. 정수장슬러지의 시용으로 대두 종실의 충실도는 향상된 반면 영양학적으로 중요한 질소 또는 인산과 같은 몇가지 무기성분의 함유량이 낮았고, 당근에 대한 슬러지 시용에서는 유효성분인 ${\beta}$-carotene의 함량을 증진 시켰으나, 외관적인 품질을 떨어뜨리는 결과를 가져왔다. 이로써 정수슬러지는 대두 및 당근의 품질에 이익과 유해한 효과를 동시에 가져다 주는 것으로 보인다.

• 한국자원식물학회:학술대회논문집
• /
• 한국자원식물학회 2018년도 추계학술대회
• /
• pp.73-73
• /
• 2018

Bacterial leaf blight(BLB), caused by X. oryzae pv. oryzae(Xoo), is one of the most destructive diseases of rice due to its high epidemic potential. Understanding BLB resistance at a genetic level is important to further improve the rice breeding that provides one of the best approaches to control BLB disease. In the present investigation, a collection of 192 accessions was used in the genome-wide association study (GWAS) for BLB resistance loci against four Korean races of Xoo that were represented by the prevailing BLB isolates under Xoo differential system. A total of 192 accessions of rice germplasm were selected on the basis of the bioassay using four isolated races of Xoo such as K1, K2, K3 and K3a. The selected accessions was used to prepare 384-plex genotyping by sequencing (GBS) libraries and Illumina HiSeq 2000 paired- end read was used for GBS sequencing. GWAS was conducted using T ASSEL 5.0. The T ASSEL program uses a mixed linear model (MLM). T he results of the bioassay using a selected set of 192 accessions showed that a large number of accessions (93.75%) were resistant to K1 race, while the least number of accessions (34.37%) resisted K3a race. For races K2 and K3, the resistant germplasm proportion remained between 66.67 to 70.83%. T he genotypic data produced SNP matrix for a total of 293,379 SNPs. After imputation the missing data was removed, which exhibited 34,724 SNPs for association analysis. GWAS results showed strong signals of association at a threshold of [-log10(P-value)] more than5 (K1 and K2) and more than4 (K3 and K3a) for nine of the 39 SNPs, which are plausible candidate loci of resistance genes. T hese SNP loci were positioned on rice chromosome 2, 9, and 11 for K1 and K2 races, whereas on chromosome 4, 6, 11, and 12 for K3 and K3a races. The significant loci detected have also been illustrated, NBS-LRR type disease resistance protein, SNARE domain containing protein, Histone deacetylase 19, NADP-dependent oxidoreductase, and other expressed and unknown proteins. Our results provide a better understanding of the distribution of genetic variation of BLB resistance to Korean pathogen races and breeding of resistant rice.

• 대한본초학회지
• /
• 제21권2호
• /
• pp.189-195
• /
• 2006

Objectives : The purpose of this study was to investigate the anti-inflammatory effects of extract Asarum sieboldii(AS) on the peritoneal macrophage. Methods : To evaluate of anti-inflammatory of AS, we examined cytokines production in lipopolysacchride (LPS)-induced macrophages. Furthermore, we checked molecular mechanism using western blot. Results : 1. Extract from AS reduced LPS-induced Nitric oxide (NO), tumor necrosis factor-a (TNF-a), interleukin (IL)-6 and IL-12 production in peritoneal macrophages 2. Extract from AS itself does not have any cytotoxic effect. AS inhibited the activation of mitogen-activated protein kinases (MAPKs) such as p38, extracelluar signal-regulated kinase B a (IkBa) in the LPS-stimulated peritoneal macrophages Conclusion : AS down-regulated LPS-induced NO and cytokines production, which could provide a clinical basis for anti-inflammatory properties of AS

• 대한화학회지
• /
• 제4권1호
• /
• pp.18-26
• /
• 1957

There are two problems to be solved by our efforts in the enamel frit. One is how we can cover the enamel frit thin with complete milk white as possible, and the other is how it can be, made resistant for chemicals than before one. The frit which can solved the two problems just mentioned above is titanium enamel frit. This frit has been developed in America after War Ⅱ, and now the research for concerning antimony frit into titanium frit is under development entirely. In order to develope the enamel industry in Korea, it is urgent problem to convert antimony frit into titanium frit. By the way the titanium frit is emulsified titanium oxide crystal which made through reheating the supersaturated solution of titanium oxide in the basis of glass. Unfortunately, there are many obscure points in active fact or which influence on its composition and characteristics yet. However, this task was tried for the first in Korea. As first step, the test was carried on the reference books, and we can be possible convert antimony frit into titanium frit as a result of this experiment. As a conclusion, for the purpose of developing the enamel industry in Korea, we studied that the research for converting antimony enamel frit which has been used popularly into titanium enamel frit which is more economic and resistant for chemicals. As a result of experiments, the following points concerning with titanium frit have become clearly. 1. It is better when the composition of titanium enamel frit has as following table.Man Duck San Silica 24 An Yang Feldspar 20 Borax 28 Sodium Nitrate 4 Cryolite 7 Calcium Carbonate 3.6∼1 Titanium Oxide 10 Calcium phosphate 0 ∼3.2 Calcium Fluoride 0∼1.8 Antimony Oxide 0∼0.5 2. The amount of $TiO_2$, to be added is $10%\;to\;12{%,\;CaF_2\;is\;under\;1.8%,\;P_2O_5\;is\;under\;1.6%,\;Sb_2O_3\;is\;under\;0.5%$. 3. In the titanium frit, the limit of iron oxide amount to be included is under 0. 5%. 4. Comparing the titanium enamel frit with antimony enamel frit not only the titanium frit can be savely 20.6% in the price of raw materials, but one time of glazing and heating process is omitted in each case, and it is known the titanium frit is more resistant for chemicals than antimony frit.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제18권2호
• /
• pp.123-129
• /
• 2007

Objectives: Autism is a complex neurodevelopmental spectrum disorder with a strong genetic component. Previous neurochemical and genetic studies have suggested the possible involvement of the serotonin system in autism. Tryptophan 2,3-dioxygenase(TDO2) is the rate-limiting enzyme in the catabolism of tryptophan, which is the precursor of serotonin synthesis. The aim of this study was to investigate the association between the TDO2 gene and autism spectrum disorders(ASD) in a Korean population. Methods: The patients were diagnosed with ASD on the basis of the DSM-IV diagnostic classification outlined in the Korean version of the Autism Diagnostic Interview-Revised and Autism Diagnostic Observation Schedule. The present study included the detection of four single nucleotide polymorphisms(SNPs) in the TDO2 gene(rs2292536, rs6856558, rs6830072, rs6830800) and the family-based association analysis of the single nucleotide polymorphisms in Korean ASD trios using a transmission disequilibrium test(TDT) and haplotype analysis. The family trios of 136 probands were included in analysis. 87.5% were male and 86.0% were diagnosed with autism. The mean age of the probands was $78.5{\pm}35.8$ months(range: 26-264 months). Results: Two SNPs showed no polymorphism, and there was no significant difference in transmission in the other two SNPs. We also could not find any significant transmission in the haplotype analysis(p>.05). Conclusion: We could not find any significant statistical association between the transmission of SNPs in the TDO2 gene and ASD in a Korean population. This result may not support the possible involvement of the TDO2 gene in the development of ASD, and further exploration might be needed to investigate other plausible SNP sites.

• 한국지리정보학회지
• /
• 제21권3호
• /
• pp.189-204
• /
• 2018

본 연구는 북한 및 비무장지대 등 접근불능지역에 대한 기상에 의한 산불발생예측 알고리즘을 개발하고, 실제 현장과 현업에서 활용할 수 있는 실시간 산불위험예보 체계를 개발하는데 있다. 산불기상위험지수 산출 모형 개발을 위해 자료의 취득과 검증을 위한 현장조사가 불가능하다는 연구적 한계가 존재하므로, 이를 해결하기 위해 MODIS 위성자료를 활용하여 접근이 불가능한 지역의 산불발화지점(fire spot)을 과학적 근거를 가지고 추정하였다. 추출된 산불발화지점을 대상으로 기상청에서 생산된 과거 기상 재분석자료(5㎞ 해상도)를 활용하여 산불발화지점에 대한 기상특성을 추출하여 데이터베이스화 하였다. 접근불능지역의 산불발화지점에서 추출된 기상요소들은 산불발생과 기상요인들과의 통계적 상관성과 산불발생 유무(산불발생 1, 산불 미발생 0)를 추정할 수 있는 로지스틱 회귀모형을 활용하여 실시간 기상변화에 의한 산불기상위험지수(Fire Weather Index, FWI)를 개발하였다. FWI 모형의 예측정확도는 66.6%로 나타나 모형의 적합도는 비교적 높은 것으로 나타났다. 이 연구결과는 남 북한의 산불 방지를 위한 정책 입안자들의 의사결정에 유용하게 활용될 것으로 기대한다.

• 치위생과학회지
• /
• 제14권2호
• /
• pp.107-113
• /
• 2014

2009년 제 4기 3차년도 국민견강영양조사 자료를 이용하여 우리나라 성인의 치주질환과 당뇨병의 관련성에 대해 평가하고자 하였다. 지역사회치주지수와 혈액검사를 통해 당뇨병을 진단받거나 공복혈당장애에 대한 검사와 당화혈색소 자료가 모두 있는 만 19세 이상의 성인 4,830명이 최종분석대상자가 되었다. 치주질환의 유병률은 성별에 따라서는 남자인 경우, 연령에 따라서는 나이가 많은 경우, 월평균가 수수입과 교육수준이 낮을수록, 흡연 경험이 있고 현재 흡연자일수록, 음주량이 많을수록 높게 나타났다. 당뇨병의 경우 남자인 경우, 나이가 많고, 현재 흡연자일수록, 교육수준과 소득수준이 낮고 음주량과 간식섭취가 많을수록 유병률이 높게 나타났다. 공복혈당수치에 따른 치주질환 유병률은 공복혈당 100 mg/dl 미만은 38.6%, 100 mg/dl 이상은 57.9%로 나타나 100 mg/dl 이상에서 치주질환이 많았다(p<0.0001). 공복혈당장애의 위험은 지역사회치주지수검사에서 CPI가 0~ 2인 그룹을 기준으로 하였을 때 CPI가 3~4인 그룹이 2.18배 높게 나타났다.

• 한국환경보건학회:학술대회논문집
• /
• 한국환경보건학회 2003년도 Challenges and Achievements in Environmental Health
• /
• pp.157-157
• /
• 2003

To evaluate an effect of pathological liver damage on the cyclohexane metabolism, rats were pretreated with 50% $CCl_4$ dissolved in olive oil (0.1$\mell$/100g body weight) 10 or 17 times intraperitoneally at intervals of every other day. On the basis of liver function and histological findings, the animals pretreated with $CCl_4$ 10 times were identified as acutely liver damaged ones and the animals pretreated with $CCl_4$ 17 times were identified as severly liver damaged ones, with fibrosis, biliary abnormality and mild injury both in the kidneys and the lungs. To these liver damaged animals, cyclohexane (a single dose of 1.56g/kg body weight, i.p.) was administrated at 48 hours after the last injection of $CCl_4$. The rats were sacrificed at 4 or 8 hours after injection of cyclohexane. The cyclohexane metabolites; cyclohexanol (CH-ol), cyclohexane-1, 2-diol (CH-1, 2-diol), cyclohexane-l, 4-diol (CH-1, 4-diol), and their glucuronyl conjugates and cyclohexanone (CH-one) were detected in the urine of cyclohexane treated rats. After cyclohexane treatment, the serum levels of CH-ol and CH-one were remarkably increased at 4 hours and then decreased at 8 hours in normal group. Whereas in liver damaged rats, these cyclohexane metabolites were higher at 8 hours than at 4 hours. The excretion rate of cyclohexane metabolites from serum into urine was more decreased in liver damaged animals than normal group, with the levels of excretion rate being lower in $CCl_4$ 17 times injected animals than 10 times injected ones. However, it was interesting that the urinary concentration of cyclohexane metabolites was generally more increased in liver damaged animals than normal ones, and the increasing rate was higher in $CCl_4$ 17 times injected rats than 10 times injected ones. And liver damaged rats, especially $CCl_4$ 17 times treated ones, had an enhanced ability of glucuronyl conjugation to cyclohexanol analogues compared with normal group. Futhermore, CH-1, 2 and 1, 4-diol were all conjugated with glucuronic acid in $CCl_4$ 17 times injected animals. In conclusion, the metabolic rate of cyclohexane was unexpectably accelerated and it may be caused by physiological adaptation of adjacent intact hepatocyte in damaged liver.

• Journal of Ecology and Environment
• /
• 제29권3호
• /
• pp.265-275
• /
• 2006

대구 인접지역 삼림식생에 대한 진행천이의 메카니즘과 잠재자연식생을 추정하였다. DCA 에 의한 요인 분석에서는 해발 고도 및 습도구배에 따라 각 군락의 특성이 결정되는 것으로 나타났으며, 토양의 수분 함량과 유기물 함량 및 전질 소량은 군락이 발달함에 따라 높아지는 것으로 나타났다. 종관 연관분석에서는 2개의 종집단으로 크게 구분되었으며, 이들 두 집단의 유형을 결정하는 요인은 기온 및 토양의 수분 요인으로 판단되었다. 특히, 두 종집단은 천이의 진행에 따라 종조성이 달라지는 군락의 발달단계를 보여주는 것으로 보이며, 생활형 조성도 이를 뒷받침하였다. 입지요인 및 종조성에 따라 소나무 군락, 굴참나무군락, 상수리나무군락 및 떡갈나무군락은 졸참나무군락이나 신갈나무군락으로 각각 천이가 진행될 것으로 예측되었다. 본 조사지역의 잠재자연식생은 종조성, 토양환경 및 지형요인에 의하여 산지 중 상부의 신갈나무군락, 계곡부의 고로쇠나무-까치박달군락, 산지 중 하부는 졸참나무군락 의 3개 유형으로 구분되었다. 그리고 신갈나무군락과 고로쇠나무-까치박탈군락은 현존 식생이면서 잠재자연식생이며, 소나무군락은 현재의 종조성 및 해발 영역을 토대로 신갈나무군락과 졸참나무군락으로 각각 발달할 것으로 예측되었다.

• 한국환경과학회지
• /
• 제22권3호
• /
• pp.259-267
• /
• 2013

In this study, non-point source(NPS) contribution was investigated based on flow rates and water qualities of streams into the lake during rainfall events. Event mean concentration(EMC) and the pollution loads were calculated to establish a database for NPS control measurement in the survey area, and so on. The runoff characteristics of NPS were investigated and estimated on the basis of the ratio of an agricultural to forest area in the stream of sub-catch basin during rainfall events. Non-point source pollution loads were also calculated to establish a database for NPS control measure in the upstream lake Chinyang. At a rainfall event, BOD concentrations rise sharply at the early peak time of runoff, however, peaks of TSS concentration were observed at the similar time of peak flow. This was a phenomenon shown at the watersheds caused by forest and geological types. The discharged EMC range was 2.9-4.8 mg/L in terms of BOD. The discharged EMC range was 6.2-8.2 mg/L in terms of SS. The discharged EMCs of T-N and T-P were 1.4-2.5 mg/L and 0.059-0.233 mg/L, respectively. Total BOD loading rate through the 3 tributaries to the lake Chinyang was 1,136 kg/d during dry weather. The upper watershed area of the Nam-river dam in this study was divided into 14 catchment basins based on the Korean guideline for total maximum daily load(TMDL) of water quality pollutants. The higher the agricultural land-use ratio, the more NPS loading rate discharged, but the more occupied a forest area, the lower more NPS loading rate discharged. In an agricultural land-use area more than 20%, the increase of NPS loadings might be dramatically diffused by increasing the integrated complex-use like vinyl-house facilities and fertilizer use etc. according to the effective land-use utilization. The NPS loading rates were BOD 0.3 $kg/ha{\cdot}day$, SS 0.21 $kg/ha{\cdot}day$, TN 0.02 $kg/ha{\cdot}day$, TP 0.005 $kg/ha{\cdot}day$ under less than 10% agricultural land-use. In agricultural land-use of 20%-50%, these values were investigated in the range of 0.32 $kg/ha{\cdot}day$-0.73 $kg/ha{\cdot}day$ for BOD, 0.92 $kg/ha{\cdot}day$-3.32 $kg/ha{\cdot}day$ for SS, 0.70 $kg/ha{\cdot}day$-0.90 $kg/ha{\cdot}day$ TN, 0.03 $kg/ha{\cdot}day$-0.044 $kg/ha{\cdot}day$ for TP.