• Journal of Embryo Transfer
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• v.26 no.4
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• pp.297-304
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• 2011

Polybrominated diphenyl ethers (PBDEs) are a class of "brominated" (bromine containing) man-made chemicals used as flame retardant additives in plastics, foams, and textiles. PBDEs are found in various environmental contaminants in air, soil, sediment, and water, and 209 individual forms (congeners) of PBDE exist. Among these, 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) is the dominant congener found in the environment. Exposure to BDE-47 is now worldwide, and levels of BDE-47 have been detected in the blood of animals, including humans. BDE-47 can adversely affect the developmental system in both humans and animals. BDEs have structural similarities to polychlorinated biphenyls and thyroid hormones. However, recent studies have shown that BDEs may act as hormonal disrupting chemicals with detrimental effects. Therefore, a reliable assessment of BDE-47 toxicological action is required to understand the detrimental impacts of BDE-47 on human health. In this review, we overview recent studies on the distribution and potential toxicological effects of BDE-47 in humans and animals.

• Korean Journal of Acupuncture
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• v.22 no.4
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• pp.169-174
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• 2005

Objectives : Functional Cerebrospinal Therapy (FCST) is a new physiologic therapeutics developed in Korea as a meridian yinyang balance approach. The theory of yinyang balance has been at the core of health enhancement approach of meridian and acupuncture medicine ever since its start. Methods : Introductory overview of FCST is presented in relation with meridian yinynag balance theory. Results : As the temporomandibular joint (TMJ) and related tissues have direct interconnection with brainstem proprioceptive or motor systems and the face is where all the meridians converge, FCST applies a fine adjustment of the posture of TMJ as a treatment tool for neurologic conditions or meridian imbalances. Conclusions : Highly sophisticated diagnostic and therapeutic techniques to adjust various subset aspects of yinyang balance are developed within FCST, which is supposed to be one of major contributions to natural healing.

• Journal of Sasang Constitutional Medicine
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• v.26 no.3
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• pp.213-223
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• 2014

Objectives This study was aimed to develop the clinical practice guideline for Soyangin symptomatology. It discussed the principle and method of application of clinical practice guideline for Soyangin symptomatology which focuses on symptomatology, not disease. Methods Based on the previous guidelines, we assessed the guidelines by Appraisal of Guidelines for Research and Evaluation (AGREE II). After AGREE II assessment, we chose and revised the clinical practice guideline. Member of writing committee reviewed and examined "Donguisusebowon" and many articles for developing clinical practice guidelines. Draft of clinical practice guideline was reviewed by advisory committee and approved by Society of Sasang Constitutional Medicine. Results & Conclusions By researching and discussing the Soyangin symptomatology, we establish the evaluation criteria for diagnosis including classification, definition and develop diagnostic algorithm and treatment assessing tool.

• Journal of Microbiology and Biotechnology
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• v.20 no.1
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• pp.5-14
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• 2010

Enterohemorrhagic Escherichia coli O157:H7 is a major foodborne pathogen causing severe disease in humans worldwide. Healthy cattle are a reservoir of E. coli O157:H7, and bovine food products and fresh produce contaminated with bovine waste are the most common sources for disease outbreaks in the United States. E. coli O157:H7 also survives well in the environment. The abilities to cause human disease, colonize the bovine gastrointestinal tract, and survive in the environment require that E. coli O157:H7 adapt to a wide variety of conditions. Three major virulence factors of E. coli O157:H7 have been identified including Shiga toxins, products of the pathogenicity island called the locus of enterocyte effacement, and products of the F-like plasmid pO157. Among these virulence factors, the role of pO157 is least understood. This review provides a board overview of E. coli O157:H7 with an emphasis on pO157.

• Journal of Sasang Constitutional Medicine
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• v.26 no.1
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• pp.1-10
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• 2014

Objectives This study was aimed to develop the clinical practice guideline for Soeumin symptomatology. This was the first clinical practice guideline, which focuses on symptomatology, not disease. Methods Donguisusebowon and many articles were reviewed and examined for developing clinical practice guidelines. Among the previous guidelines, we assessed the guidelines by Appraisal of Guidelines for Research and Evaluation (AGREE II). After AGREE II assessment, we chose and revised the clinical practice guideline. Results & Conclusions By researching and discussing the Soeumin symptomatology, we make the principle of the clinical practice guideline, including classification, definition, algorithm, and treatment assessing tool.

• Journal of Sasang Constitutional Medicine
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• v.27 no.1
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• pp.1-12
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• 2015

Objectives This study was aimed to develop the clinical practice guideline for Taeeumin, Taeyangin symptomatology. This was the second clinical practice guideline, which focuses on symptomatology. Methods Donguisusebowon and many articles were reviewed and examined for developing clinical practice guidelines. Among the previous guidelines, we assessed the guidelines by Appraisal of Guidelines for Research and Evaluation (AGREE II). After AGREE II assessment, we chose and revised the clinical practice guideline. Results and Conclusions By researching and discussing the Taeeumin, Taeyangin symptomatology, we make the principle of the clinical practice guideline, including classification, definition, algorithm, and treatment assessing tool.

• Journal of Korean Medicine Rehabilitation
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• v.34 no.1
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• pp.49-64
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• 2024

Objectives By bibliographically analyzing acupuncture treatment studies for temporomandibular disorders over the past 20 years, we found an overview of global trends and a new perspective on future research directions. Methods We searched on the Web of Science webpage through the formula (TS=[temporomandibular] OR TS=[craniomandibular] OR TS=[jaw]) AND (TS=[^*acupuncture] OR TS=[dry needl^*] OR TS=[warm needl^*] OR TS=[thread embed^*]) AND (PY=[2003-2022]). And it was analyzed by year, research field, academic journal, country, research institute, author, and keyword. Results 194 papers were searched, and 92 papers were finally selected. The number of papers published over the past 20 years has been on the rise. Research has been the most active in the field of Dentistry Oral Surgery Medicine. Brazil published the most papers. And by institution, Universidade de Sao Paulo published the most papers. Among the authors, Fernández-de-las-Peñas has published the most papers. In the analysis by keyword, the top five keywords were temporomandibular joint disorder, acupuncture, myofascial pain, pain and management. Conclusions This study will provide useful guidelines for setting the direction of research by referring to the research status and keyword analysis when conducting research on the acupuncture on temporomandibular disorder in the future.

• Journal of Korean Medical Ki-Gong Academy
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• v.20 no.1
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• pp.15-67
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• 2020

Objective : The purpose of this study is to identify the trends of vibration(or wave) therapy in Korea, to actively utilize vibration(or wave) therapy, and to help research activities of vibration therapy in Korean Medicine. Methods : The following Korean words "진동기", "진동요법", "진동운동", "진동치료", "파동요법", "파동운동", "파동치료" were searched on three specialized search sites (RISS, NAL, DBpia). Trends of vibration therapy were analyzed through the selected researches suitable for this study among these searched researches in an overview format. Results : 1. A total of 8,116 studies were searched and a total of 365 studies were finally selected 2. From 2000 to 2019, when research began to increase in earnest, there were 17.45±10.28 studies per year, and the AGR(Average Annual Growth Rate) was 11.92%. 3. In the main field of research, the 'Medicine and Pharmacy' was the largest with 147(40.16%) studies. In the Middle Field, the 'Kinesiology' was the largest with 99(27.05%) studies. In the study design, 'RCT(Randomized Controlled trial)' was the largest with 138(47.75%) studies. In the Age Group, 'Youth' was the largest with 126(48.84%) studies. 4. The average of the number of participants was 24.90±17.44. 5. The most used Intervention was the 'WBV(Whole Body Vibration)' with 177(61.25%) studies. 6. The average of Intervention Period was 5.99±4.14 weeks, while the maximum was 36 weeks. 7. The journal that published the most research papers is 'K. J. of Sports Science(체육과학연구;13)', and the society is 'Rehabilitation Engineering And Assistive Technology Society of Korea(한국재활복지공학회; 14)'. The University that published the most dissertations is 'Sahmyook University(11)'. 8. The authors who published the most studies are Ju-Hwan O(8) as the main author and Tae Kyu Kwon(18) as the co-author (including the thesis Director). In an integrated analysis of the authors and co-authors, Tae Kyu Kwon published the most numerous studies(19) Conclusions : 1. The study of vibration or wave therapy has been increasing noticeably every year. 2. The major academic Fields studying vibration or wave therapy are the 'Kinesiologic Field', 'Physical Therapy Field', and 'Biomedical Engineering Field'. 3. The most chosen method of study design on vibration or wave treatment was 'RCT', and there was no significant change in the annual presentation rate. 4. Types of vibration or wave therapy could be classified as 'LVS(Local Vibration Stimulation)', 'WBV(Whole Body Vibration)', 'MV(Micro Vibration)', 'BV(Bio Vibration)' and 'SWV(Sound Wave Vibration)', and the study on Whole Body Vibration is most active. 5. Most of the studies of vibration or wave therapy were on musculoskeletal systems, but there were very few studies on internal diseases.

• The Journal of Korean Medicine
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• v.28 no.3 s.71
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• pp.116-125
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• 2007

Objective : To overview the protocols of clinical acupuncture research on cancer in the USA. Methods : Using 'acupuncture' and 'cancer' as keyword search terms in Clinical Trials. gov, 28 clinical studies were found. Three studies by non-American institutions were excluded and 25 studies were analyzed. Analytic parameters were cancer condition, primary outcome, research institution, study design, and acupuncture intervention. Results : Breast cancer was the most frequent single condition in the searched protocols. Pain and quality of life were the primary outcomes in many studies. Memorial Sloan-Kettering Cancer Centerin New York has performed the largest number of acupuncture cancer studies. The majority of studies were randomized controlled trials with active controls or placebo/sham controls. Total enrollment varied between the range of 10 and 700 subjects and ages of these subjects were at least above 18 years old (except one protocol). Most protocols had strict exclusion criteria for acupuncture needling such as bleeding disorders, infection, heart disorder, and central nervous system disorder. Conclusions : Clinical acupuncture studies for cancer patients have focused on pain, quality of life, and side effects induced by anti-cancer therapies. Re-evaluation and cautions for strict exclusion criteria in foreign countries are required to perform multi-national acupuncture trials.

• The Journal of Internal Korean Medicine
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• v.38 no.4
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• pp.443-454
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• 2017

Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent. Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed. Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects. Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.