• 동의신경정신과학회지
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• 제34권2호
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• pp.95-113
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• 2023

Objectives: To review studies evaluating effects of acupuncture on pain and depressive symptoms in fibromyalgia. Methods: Quantitative evidences (RCTs) were systematically reviewed. Literature were searched for a combination of fibromyalgia and depression (The Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, medline (via PubMed), Kmbase, KISS, ScienceON, OASIS, CiNii, CNKI). Quantitative research findings were critically appraised by Cochrane risk of bias (RoB) tool and pooled. Meta-analysis was then conducted using Review Manager (RevMan) 5.4. Results: Eighteen studies were selected. American College of Rheumatology (ACR) classification criteria for Fibromyalgia Syndrome was most frequently used as diagnostic criteria for fibromyalgia. As for outcome measurement, Hamilton Rating Scale for Depression (HAMD), Visual Analog Scale (VAS), and Total Effective Rate (TER) were used most commonly. Meta-analysis of ten studies revealed that both Depression and VAS scores of the Acupuncture+Western Medicine group were significantly lower than those of Western Medicine group (Depression: SMD, -0.94, 95% CI, -1.17 to -0.70; VAS: MD, -1.51, 95% CI, -1.83 to -1.19). Also, TERs of both Acupuncture group and Acupuncture+Western Acupuncture+Western Medicine group were significantly higher than those of the Western Medicine group (OR: 2.38, 95% CI: 1.29 to 4.41; and OR: 7.40, 95% CI: 3.41 to 16.07). There was no significant difference in Depression or VAS score between the Acupuncture Group and the Western Medicine Group. Conclusions: Acupuncture might be an effective option for pain and depressive symptoms of fibromyalgia when it is combined with Western Medicine treatment. For more accurate results, more types of Korean medicine treatment should be conducted.

• 한방재활의학과학회지
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• 제33권3호
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• pp.97-113
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• 2023

Objectives This study examined the trends in domestic and international research on the treatment of sarcopenia and analyzed the effectiveness of the treatment. Based on the results, we suggest directions for future Korean medicine research on sarcopenia. Methods The study was conducted using Arksey and O'Malley's scoping review methodology. It included three international databases (PubMed, EMBASE, Cochrane Library) and five domestic databases (Korean studies Information Service System, Korean Medical database, Oriental Medicine Advanced Search Integrated System, Research Information Sharing Service, ScienceON) were used. Literatures published until April 30, 2023, including the contents of 'sarcopenia' and Korean Medicine treatment', were searched. Results A total of 45 studies were included in the analysis. The number of studies on Korean medicine treatments for sarcopenia is steadily increasing, with the majority of studies coming from Asian countries. Of the 45 studies, 30 were conducted in the field of medicine, and the study design was analyzed into 10 clinical studies and 35 non-clinical studies. Among the 10 clinical studies, the most common treatment interventions were herbs (n=4), followed by Daoist exercises (n=3). The most common diagnostic criteria used in clinical studies were those published by the Asian working group for sarcopenia, and various physical examinations and laboratory tests were used as outcome measures. Conclusions The future direction of Korean medicine research on sarcopenia should be to expand the number of clinical studies applying Korean medicine treatment interventions.

• 대한융합한의학회지
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• 제3권1호
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• pp.5-13
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• 2022

Objectives: Smoking had a long negative impact on public health. The ingredients of a cigarette are major risk factors for several diseases. Owing to the problems about economic and quality of life, we need to ensure smoking cessation (SC). There are several approaches for SC including pharmacological therapy, nicotine replacement therapy, education, and behavioral intervention. However, due to some limitations, other alternative approaches are gaining popularity. Acupuncture has been reported to have few side effects and be more effective than some conventional treatments in several articles. However, there are no systematic reviews on the comparison of acupuncture combination treatment with other conventional monotherapies. Methods: Randomized controlled trials that used acupuncture as an adjunct treatment for SC will be searched and data will be summarized according to the predefined criteria. The primary outcome will be the abstinence rate, and secondary outcomes will be adverse events and biochemical indicators. We will use Review Manager to perform a meta-analysis, Cochrane Collaboration Risk of Bias tool for the risk of bias assessment, and the Grades of Recommendation, Assessment, Development and Evaluation approach to determine the quality of evidence. We will investigate the efficacy and safety of acupuncture combination treatment for SC with this study. Ethics and dissemination: This study will provide reliable clinical evidence on additional effect of acupuncture on smoking cessation. We will publish our results in a peer-review journal.

• 한국식생활문화학회지
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• 제22권4호
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• pp.492-497
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• 2007

본 연구는 2000에서 2004년까지 5년 동안 방송 3사와 신문 3사에서 비브리오에 관한 보도기사를 내용분석 하여 언론의 비브리오 관련 보도에 대한 실태를 파악하고, 이를 통해서 사회적 관심을 높이고자 하였다. 기존 비브리오에 관련된 연구는 생물학적 관점에서 균의 특성이나 방지 시스템 또는 예방에 관한 것이 대부분이므로 비브리오에 관한 언론의 보도를 좀 더 객관적ㆍ체계적으로 조명하고 이러한 보도에 따른 부정적 영향을 줄이기 위한 방안에 초점을 맞추는 것이 연구의 목적이라 할 수 있다. 본 연구의 주요 분석결과를 요약하면 다음과 같다. 비브리오 관련보도기사는 방송이 신문보다 많았고, 여름철 5월에서 9월 사이에 집중적으로 보도되었다. 기사유형은 뉴스가 압도적으로 많았고, 지면은 사회면이 가장 많았다. 대부분의 기사는 40줄 이하로 짧았고, 전체기사 중에 23.6%는 유사보도였다. 유사보도를 긍정적인 면에서 해석을 한다면 비브리오에 국한된 보도 보다는 다양한 장르에서 폭넓은 정보를 전해 준다고 볼 수 있다. 기사제목에 비브리오라는 단어가 대부분 포함 되어 있고 주의보 발령, 감염자 입원치료, 감염자 사망 등을 집중적으로 부각하고 있다. 반면에 퇴치노력이나 예방조치 사항은 상대적으로 적게 다루고 있다. 따라서 비브리오는 혐오스러운 전염병으로 인식이 되어 외식업에는 상당히 부정적으로 작용하고 있다. 내용의 강도에서는 저강도와 고강도가 비슷했고, 방향은 대체적으로 부정적이었다. 정보원은 지자체 보건당국, 국립보건원과 감염자의 진료병원 등의 비중이 컸다. 보도의 중심은 상대적으로 생산과 유통 및 외식관련업계의 입장을 고려하는 보도기사가 미흡했다. 기사의 표현방식은 사실적이고, 자극적인 기사가 많았고, 전문적이고, 분석적이며, 심층적인 기사가 상대적으로 매우 적었다. 기사의 성격은 사실기사가 압도적으로 많은 반면에 기획이나 분석기사는 적었다. 감염자의 연령은 40대에서 60세 사이의 중장년층이 가장 많았고, 감염자의 성별은 남녀가 비슷했다. 그러나 성별을 구별할 수 없는 기사의 비중이 많았다. 매체별 기사의 특성분석 결과는 다음과 같다. 매체별 기사강도는 전반적으로 방송보도가 신문기사 보다 고강도로 나타났으며, 기사의 방향에 있어서도 방송이 신문보다 부정적인 면이 높게 분석되었다. 매체별 기사의 중심은 생산자의 입장에서는 방송보다 신문이 높게 나타났으며, 소비자의 입장에서는 방송이 신문보다 훨씬 높았다. 방송과 신문 모두 지자체 보건당국과 국립보건원, 감염자를 진료한 병원에서 정보를 얻는 것으로 분석되었다. 기사의 표현방식은 방송이 신문보다 더 자극적이고 혐오적인 표현이 많은 것으로 분석되었다. 기사의 성격에서는 신문과 방송 모두 사실기사가 91.5%로서 대부분을 차지했다. 유사보도에 있어서는 방송이 23.0%이고, 신문은 77.0%로서 신문이 훨씬 많았다. 유사보도를 긍정적인 측면에서 보았을 때 보다 폭넓은 정보를 제공해준다는 면이 있고, 방송보다는 신문이 더 많이 다루고 있음을 알 수 있다.

• 한국심리학회지 : 문화 및 사회문제
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• 제23권2호
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• pp.159-181
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• 2017

국내의 심리학자들은 사회문제를 다루는 연구와 실천을 위하여 많은 노력을 하고 있다. 이를 표방하여 발간되는 [한국심리학회지: 문화 및 사회문제]지에 게재된 논문들을 분석하여 이같은 노력을 점검해 보고자 하였다. 1994년 발간 후 2015년까지 22년간 게재된 논문들을 연구유형, 연구내용, 연구방법에 대해 분석하였다. 총 464편의 논문 중, 실증적 연구 337편의 연구내용은 대부분이 개인수준의 변인으로 다루어졌고, 이 중 개인을 둘러싼 공동체 또는 사회문화적 환경을 분석수준으로 다룬 연구들의 비중이 낮았다(예측변인 기준 29.1%). 사회적 소수자를 비롯한 특정성격의 인구보다는 일반인을 대상으로 한 연구들이 압도적으로 많았으며(특정 직업군 일반인 포함 80.9%), 연구참가자의 인구학적 특성이 논문에 구체적으로 제시되지 않은 연구들도 다수 발견되었다. 특히 한국인이 인식하는 사회문제로 지적된 주제들(한덕웅, 최훈석, 2006)에 대한 연구는 희소하여 일반인이 인식하는 사회문제와 연구되는 주제로서의 사회문제와는 괴리가 있는 것으로 나타났다. 분석결과를 바탕으로 현대한국사회에서 심리학 및 [한국심리학회지: 문화 및 사회문제]가 할 수 있는 역할에 대하여 논의하였다.

• 한방재활의학과학회지
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• 제33권4호
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• pp.45-59
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• 2023

Objectives The aim of this study was to analyze the trends of researches on oriental medicine treatments for supraspinatus tendinopathy. Methods We used five databases for searching researches; Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, PubMed, and China National Knowledge Infrastructure. Only randomized controlled trials suitable for the subject were selected. The methodological quality of included randomized controlled trials (RCTs) was assessed by the Cochrane risk of bias tool. Results Twenty randomized controlled trials were analyzed. There were 9 types of treatment interventions; acupuncture, acupotomy, pharmacopuncture, electroacupuncture, fire needling, warming needle, catgut-embedding therapy, herbal medicine, cupping. The most frequently used treatment intervention was acupuncture and acupotomy. There were 9 outcome measurements including visual analog scale (VAS), Constant-Murley Score (CMS), and range of motion. The most used measurement was VAS. As a result of meta-analysis, acupuncture was more effective than control group in VAS. Additionally, acupotomy was clinically significant compared to control groups in VAS and CMS. Conclusions In this review, we analyzed researches on effectiveness of oriental medicine for supraspinatus tendinopathy. A provisional conclusion can be produced that acupuncture and acupotomy showed beneficial effect to supraspinatus tendinopathy. Although there were some RCT studies, many of them had a high risk of bias, so it is hard to conclude that our study can include overall clinical status. Further well-designed trials are needed.

• 한방재활의학과학회지
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• 제34권2호
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• pp.135-147
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• 2024

Objectives The aim of this study is to investigate the research trends in traditional Chinese medicine (TCM) treatment for pes anserine bursitis using the search results from the China National Knowledge Infrastructure (CNKI). Methods We searched for clinical studies on pes anserine bursitis in the CNKI electronic database. We analyzed the publication year, study type, participant demographics, treatment methods and duration, evaluation criteria, adverse events, and the results of each article. Results Seventeen studies published from January 1, 2014 to January 1, 2024 were selected. Among the 17 selected studies, 14 were randomized controlled trials and 2 were case reports. The most frequently used treatment intervention was acupuncture. Nine types of acupuncture were identified, including electro-acupuncture, pharmacopuncture, acupotomy, floating acupuncture, and other new types of acupuncture. The most commonly used evaluation outcome was effective rate. Conclusions Various TCM treatments for pes anserine bursitis were introduced, and we could identify the effectiveness of TCM in treating pes anserine bursitis. However, it is anticipated that more well-designed and high-quality evaluation studies will be required in the future.

• 한방비만학회지
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• 제24권1호
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• pp.87-93
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• 2024

Objectives: Obesity is a globally prevalent public health issue. Hence, there is a need for the development of safer and more effective anti-obesity drugs. Lythrum salicaria, a traditional medicinal herb used for centuries, has been reported to improve lipid metabolism and fat accumulation. It also has a low toxicity profile. Therefore, its potential as a functional ingredient in health functional foods needs to be evaluated. Methods: In this randomized, double-blind, placebo-controlled clinical trial, 90 participants will be randomly assigned to either the experimental or control group. Each subject will orally receive L. salicaria extract (1,350 mg/day) (500 mg L. salicaria+850 mg lactose as vehicle) or lactose (1,350 mg/day) as a hard capsule formula for 84 days (12 weeks). The primary outcome will be body fat mass (kg), which will be assessed using dual-energy x-ray absorptiometry (DXA) (performed only at visits 2 and 4). Secondary outcomes include body mass index, body weight, waist-to-hip ratio, body fat percentage (%) measured using DXA, lean body mass (kg) measured using DXA (assessed only at visits 2 and 4), lipids (total cholesterol, triglyceride, high-density lipoprotein cholesterol, and calculated low-density lipoprotein cholesterol), free fatty acid, high sensitivity C-reactive protein, adiponectin, and leptin. Conclusions: This protocol will be implemented after approval of Institutional Review Board of Pusan National University Korean Medicine Hospital (approval number: PNUKHIRB-2022-08-002) and registration with the Korean National Clinical Research Information Service (CRIS) (CRIS-KCT0008060). The results of this trial will provide potential of L. salicaria as a new anti-obesity functional food with fat-reducing effects and low toxicity.

• Korean Circulation Journal
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• 제52권12호
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• pp.865-875
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• 2022

Background and Objectives: Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure. However, in pediatric and congenital heart disease (CHD) patients, current adult indications cannot be directly applied because of heterogeneity in anatomy and diagnosis. Therefore, CRT responses and clinical outcomes in these patients were investigated to derive possible candidates for CRT. Methods: This study retrospectively analyzed 16 pediatric and CHD patients who underwent CRT implantation at a single center in early (0.7±0.2 year) and late (4.7±0.3 years) follow-up period after CRT. Results: The median age at CRT implantation was 2.5 (0.3-37.2) years, and median follow-up duration was 6.3 (0.1-13.6) years. Thirteen had non-transvenous CRT. Two had congenital complete atrioventricular (AV) block with previous right ventricular pacing, 5 had dilated cardiomyopathy (DCM) with left bundle branch block, and 9 had CHD. The mean ejection fraction of the systemic ventricle increased from 28.1±10.0% to 44.3±21.0% (p=0.003) in early and 51.8±16.3% (p=0.012) in late outcome. The mean functional class improved from 3.1±0.9 to 1.8±1.1 after CRT (p=0.003). Twelve patients (75%) showed improvement in ventricular function or functional class after CRT. Proportion of responders differed between patients without CHD (2/2 patients with complete AV block and 5/5 with DCM, 100%) and those with CHD (5/9, 56%), although statistical significance was not reached (p=0.088). Conclusions: CRT improved ventricular function and functional status according to the underlying condition in pediatric and CHD patients. However, further large and longer-term studies are needed to establish the guideline for the patient selection of CRT in these patients.

• Korean Circulation Journal
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• 제52권6호
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• pp.429-440
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• 2022

Background and Objectives: Endovascular therapy (EVT) first strategy has been widely adopted for the treatment of chronic limb threatening ischemia (CLTI) patients in real-world practice. This study aimed to investigate long-term outcomes of CLTI patients who underwent EVT and identify prognostic factors. Methods: From the retrospective cohorts of a Korean multicenter endovascular therapy registry, 1,036 patients with CLTI (792 men, 68.8 ± 9.5 years) were included. The primary endpoint was amputation-free survival (AFS) defined as the absence of major amputation or death. Secondary endpoints were major adverse limb events (MALE; a composite of major amputation, minor amputation, and reintervention). Results: Five-year AFS and freedom from MALE were 69.8% and 61%, respectively. After multivariate analysis, age (hazard ratio [HR], 1.476; p<0.001), end-stage renal disease (ESRD; HR, 2.340; p<0.001), Rutherford category (RC) 6 (HR, 1.456; p=0.036), and suboptimal EVT (HR, 1.798; p=0.005) were identified as predictors of major amputation or death, whereas smoking (HR, 0.594; p=0.007) was protective. Low body mass index (HR, 1.505; p=0.046), ESRD (HR, 1.648; p=0.001), femoropopliteal lesion (HR, 1.877; p=0.004), RC-6 (HR, 1.471; p=0.008), and suboptimal EVT (HR, 1.847; p=0.001) were predictors of MALE. The highest hazard rates were observed during the first 6 months for both major amputation or death and MALE. After that, the hazard rate decreased and rose again after 3-4 years. Conclusions: In CLTI patients, long-term outcomes of EVT were acceptable. ESRD, RC-6, and suboptimal EVT were common predictors for poor clinical outcomes.