Journal of Korean Medicine Rehabilitation (한방재활의학과학회지)

The society of Korean Medicine Rehabilitation (한방재활의학과학회)
권호 표지
DOI QR코드

DOI QR Code

Research Trends in Korean Medicine Treatment for Sarcopenia: Scoping Review

근감소증에 대한 한의 치료 연구 동향: 스코핑 리뷰

  • Seo-Eun Kim (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Yun-Hee Han (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Seung-Kwan Choi (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Jung-Ho Jo (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Hyeon-Jun Woo (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Byeong-Hyeon Jeon (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Won-Bae Ha (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University) ;
  • Jung-Han Lee (Chuna Manual Medicine Research Group, College of Korean Medicine, Wonkwang University)
  • 김서은 (원광대학교 한의과대학 추나의학연구회) ;
  • 한윤희 (원광대학교 한의과대학 추나의학연구회) ;
  • 최승관 (원광대학교 한의과대학 추나의학연구회) ;
  • 조정호 (원광대학교 한의과대학 추나의학연구회) ;
  • 우현준 (원광대학교 한의과대학 추나의학연구회) ;
  • 전병현 (원광대학교 한의과대학 추나의학연구회) ;
  • 하원배 (원광대학교 한의과대학 추나의학연구회) ;
  • 이정한 (원광대학교 한의과대학 추나의학연구회)
  • Received : 2023.06.20
  • Accepted : 2023.07.09
  • Published : 2023.07.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives This study examined the trends in domestic and international research on the treatment of sarcopenia and analyzed the effectiveness of the treatment. Based on the results, we suggest directions for future Korean medicine research on sarcopenia. Methods The study was conducted using Arksey and O'Malley's scoping review methodology. It included three international databases (PubMed, EMBASE, Cochrane Library) and five domestic databases (Korean studies Information Service System, Korean Medical database, Oriental Medicine Advanced Search Integrated System, Research Information Sharing Service, ScienceON) were used. Literatures published until April 30, 2023, including the contents of 'sarcopenia' and Korean Medicine treatment', were searched. Results A total of 45 studies were included in the analysis. The number of studies on Korean medicine treatments for sarcopenia is steadily increasing, with the majority of studies coming from Asian countries. Of the 45 studies, 30 were conducted in the field of medicine, and the study design was analyzed into 10 clinical studies and 35 non-clinical studies. Among the 10 clinical studies, the most common treatment interventions were herbs (n=4), followed by Daoist exercises (n=3). The most common diagnostic criteria used in clinical studies were those published by the Asian working group for sarcopenia, and various physical examinations and laboratory tests were used as outcome measures. Conclusions The future direction of Korean medicine research on sarcopenia should be to expand the number of clinical studies applying Korean medicine treatment interventions.

Keywords

References

  1. Kim MC, Cheon JY, Kim HI, Chung DK, Bae WS. Analysis of the correlation between sarcopenia and locomotive syndrome in the elderly in Korea. Journal of Korean Society of Integrative Medicine. 2022;10(2):1-11.
  2. Janssen I, Heymsfield SB, Baumgartner RN, Ross R. Estimation of skeletal muscle mass by bioelectrical impedance analysis. Journal of Applied Physiology. 2000;89(2):465-71. https://doi.org/10.1152/jappl.2000.89.2.465
  3. Kim TN, Park MS, Yang SJ, Yoo HJ, Kang HJ, Song W, Seo JA, Kim SG, Kim NH, Baik SH, Choi DS, Choi KM. Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS). Diabetes Care. 2010;33(7):1497-9. https://doi.org/10.2337/dc09-2310
  4. Lim SK, Kong S. Prevalence, physical characteristics, and fall risk in older adults with and without possible sarcopenia. Aging Clinical and Experimental Research. 2022;34(6):1365-71. https://doi.org/10.1007/s40520-022-02078-z
  5. Yeung SSY, Reijnierse EM, Pham VK, Trappenburg MC, Lim WK, Meskers CGM, Maier AB. Sarcopenia and its association with falls and fractures in older adults: a systematic review and meta-analysis. Journal of Cachexia, Sarcopenia and Muscle. 2019;10(3):485-500. https://doi.org/10.1002/jcsm.12411
  6. Kim JH. Concept analysis of frail elderly based on Walker and Avant's method. Journal of the Korea Academia-Industrial Cooperation Society. 2019;20(5):394-405. https://doi.org/10.5762/KAIS.2019.20.5.394
  7. Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R. The healthcare costs of sarcopenia in the United States. Journal of the American Geriatrics Society. 2004;52(1):80-5. https://doi.org/10.1111/j.1532-5415.2004.52014.x
  8. Social Statistics Planning Division Statistics Korea. 2022 elderly population statistics [serial online] 2022 Sep[cited 2023 Jun 10]. Available from: URL: https://www.kostat.go.kr/board.es?mid=a10301060500&bid=10820&act=view&list_no=420896.
  9. Social Statistics Planning Division Statistics Korea. 2019 elderly population statistics [serial online] 2019 Sep[cited 2023 Jun 10]. Available from: URL: https://www.kostat.go.kr/board.es?mid=a10301060500&bid=10820&act=view&list_no=377701.
  10. Papadopoulou SK. Sarcopenia: a contemporary health problem among older adult populations. Nutrients. 2020;12(5):1293.
  11. Barajas-Galindo DE, Gonzalez Arnaiz E, Ferrero Vicente P, Ballesteros-Pomar MD. Effects of physical exercise in sarcopenia. A systematic review. Endocrinologia, Diabetes y Nutricion. 2021;68(3):159-69. https://doi.org/10.1016/j.endinu.2020.02.010
  12. Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, Moher D, Peters MDJ, Horsley T, Weeks L, Hempel S, Akl EA, Chang C, McGowan J, Stewart L, Hartling L, Aldcroft A, Wilson MG, Garritty C, Lewin S, Godfrey CM, Macdonald MT, Langlois EV, Soares-Weiser K, Moriarty J, Clifford T, Tuncalp O, Straus SE. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Annals of Internal Medicine. 2018;169(7):467-73. https://doi.org/10.7326/M18-0850
  13. Arksey H, O'Malley L. Scoping studies: towards a methodological framework. International Journal of Social Research Methodology. 2005;8(1):19-32. https://doi.org/10.1080/1364557032000119616
  14. Levac D, Colquhoun H, O'Brien KK. Scoping studies: advancing the methodology. Implementation Science. 2010;20(5):69.
  15. Morinaga A, Nakamura H, Hattanmaru K, Rokot NT, Kimura Y, Ito T. Good rehabilitation outcomes and improved nutritional status after treatment with the Japanese herbal medicine Ninjin'yoeito in an elderly patient with hip fracture and sarcopenia: a case report. Frontiers in Nutrition. 2020;26(7):85.
  16. Lim NJ, Shin JH, Kim HJ, Lim Y, Kim JY, Lee WJ, Han SJ, Kwon O. A combination of Korean mistletoe extract and resistance exercise retarded the decline in muscle mass and strength in the elderly: a randomized controlled trial. Experimental Gerontology. 2017;87(Pt A):48-56. https://doi.org/10.1016/j.exger.2016.11.003
  17. O'Leary MF, Jackman SR, Sabou VR, Campbell MI, Tang JCY, Dutton J, Bowtell JL. Shatavari supplementation in postmenopausal women improves handgrip strength and increases vastus lateralis myosin regulatory light chain phosphorylation but does not alter markers of bone turnover. Nutrients. 2021;13(12):4282.
  18. Cho YH, Lee SY, Lee CH, Park JH, So YS. Effect of Schisandra chinensis Baillon extracts and regular low-intensity exercise on muscle strength and mass in older adults: a randomized, double-blind, placebo-controlled trial. The American Journal of Clinical Nutrition. 2021;113(6):1440-6. https://doi.org/10.1093/ajcn/nqaa447
  19. Morawin B, Tylutka A, Chmielowiec J, Zembron-Lacny A. Circulating mediators of apoptosis and inflammation in aging; physical exercise intervention. International Journal of Environmental Research and Public Health. 2021;18(6):3165.
  20. Niu K, Liu YL, Yang F, Wang Y, Zhou XZ, Qu Q. Efficacy of traditional Chinese exercise for sarcopenia: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Neuroscience. 2022;16:1094054.
  21. Huang CY, Mayer PK, Wu MY, Liu DH, Wu PC, Yen HR. The effect of Tai Chi in elderly individuals with sarcopenia and frailty: a systematic review and meta-analysis of randomized controlled trials. Ageing Research Reviews. 2022;82:101747.
  22. Soares Mendes Damasceno G, Teixeira THMM, de Souza VC, Neiva TS, Prudente Pereira K, Teles Landim MF, de Melo GF, Romao JFFE, Toledo Nobrega O, de Azevedo Carvalho G. Acupuncture treatment in elderly people with sarcopenia: effects on the strength and inflammatory mediators. Journal of Aging Research. 2019;2019:8483576.
  23. Guo CY, Ma YJ, Liu ST, Zhu RR, Xu XT, Li ZR, Fang L. Traditional Chinese medicine and sarcopenia: a systematic review. Frontiers in Aging Neuroscience. 2022;14:872233.
  24. Negm AM, Lee J, Hamidian R, Jones CA, Khadaroo RG. Management of sarcopenia: a network meta-analysis of randomized controlled trials. Journal of the American Medical Directors Association. 2022;23(5):707-14. https://doi.org/10.1016/j.jamda.2022.01.057
  25. Beaudart C, Rizzoli R, Bruyere O, Reginster JY, Biver E. Sarcopenia: burden and challenges for public health. Archives of Public Health. 2014;72(1):45.
  26. Lee YS, Kong SA. Comparison analysis of quality of life and exercise regularity in the possible sarcopenia group according to the criteria for sarcopenia diagnostic: using the 7th Korean National Health and Nutrition Examination Survey(2016~2018). Journal of Digital Convergence. 2022;20(1):361-8
  27. Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, Chou MY, Chen LY, Hsu PS, Krairit O, Lee JS, Lee WJ, Lee Y, Liang CK, Limpawattana P, Lin CS, Peng LN, Satake S, Suzuki T, Won CW, Wu CH, Wu SN, Zhang T, Zeng P, Akishita M, Arai H. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. Journal of the American Medical Directors Association. 2014;15(2):95-101. https://doi.org/10.1016/j.jamda.2013.11.025
  28. Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, Jang HC, Kang L, Kim M, Kim S, Kojima T, Kuzuya M, Lee JSW, Lee SY, Lee WJ, Lee Y, Liang CK, Lim JY, Lim WS, Peng LN, Sugimoto K, Tanaka T, Won CW, Yamada M, Zhang T, Akishita M, Arai H. Asian Working Group for Sarcopenia: 2019 Consensus update on sarcopenia diagnosis and treatment. Journal of the American Medical Directors Association. 2020;21(3):300-7. https://doi.org/10.1016/j.jamda.2019.12.012
  29. Sayer AA, Cruz-Jentoft A. Sarcopenia definition, diagnosis and treatment: consensus is growing. Age Ageing. 2022;51(10):afac220.
  30. Bauer J, Morley JE, Schols AMWJ, Ferrucci L, Cruz-Jentoft AJ, Dent E, Baracos VE, Crawford JA, Doehner W, Heymsfield SB, Jatoi A, Kalantar-Zadeh K, Lainscak M, Landi F, Laviano A, Mancuso M, Muscaritoli M, Prado CM, Strasser F, von Haehling S, Coats AJS, Anker SD. Sarcopenia: a time for action. An SCWD position paper. Journal of Cachexia, Sarcopenia and Muscle. 2019;10(5):956-61. https://doi.org/10.1002/jcsm.12483
  31. Lee SH. Review on Wei symptom in general with this rare clinical study on 1case of patient with Wei symptom finally dianosed as Guillain-Barre syndrome and whether distinction should be made in treatment and categorizating in clinical aspect. Journal of Physiology & Pathology in Korean Medicine. 2007;21(1):298-302.
  32. Kim KM, Kang HJ. Effects of resistance exercise on muscle mass, strength, and physical performances in elderly with diagnosed sarcopenia: a systematic review and meta-analysis. Exercise Science. 2020;29(2):109-20. https://doi.org/10.15857/ksep.2020.29.2.109
  33. Shin JS, Kim HJ. The effect of 12-week resistance exercise on muscle loss and metabolic syndrome-related variables in obese elderly with sarcopenia. Journal of The Korean Society of Integrative Medicine. 2022;10(4):165-73.
  34. Ni Lochlainn M, Bowyer RCE, Steves CJ. Dietary protein and muscle in aging people: the potential role of the gut microbiome. Nutrients. 2018;10(7):929.
  35. Liao Y, Peng Z, Chen L, Zhang Y, Cheng Q, Nussler AK, Bao W, Liu L, Yang W. Prospective vews for whey protein and/or resistance training against age-related sarcopenia. Aging and Disease. 2019;10(1):157-73. https://doi.org/10.14336/AD.2018.0325
  36. Yin L, Li N, Jia W, Wang N, Liang M, Yang X, Du G. Skeletal muscle atrophy: from mechanisms to treatments. Pharmacological Research. 2021;172:105807.