• Journal of Trauma and Injury
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• 제32권2호
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• pp.86-92
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• 2019

Purpose: There is increasing interest in intra-abdominal pressure (IAP) and intra-abdominal hypertension (IAH) in critically ill patients. This study investigated the effects and outcomes of elevated IAP in a trauma intensive care unit (ICU) population. Methods: Eleven consecutive critically ill patients admitted to the trauma ICU at Pusan National University Hospital Regional Trauma Center were included in this study. IAP was measured every 8-12 hours (intermittently) for 72 hours. IAP was registered as mean and maximal values per day throughout the study period. IAH was defined as $IAP{\geq}12mmHg$. Abdominal compartment syndrome was defined as $IAP{\geq}20mmHg$ plus ${\geq}1$ new organ failure. The main outcome measure was in-hospital mortality. Results: According to maximal and mean IAP values, 10 (90.9%) of the patients developed IAH during the study period. The Sequential Organ Failure Assessment (SOFA) score was significantly higher in patients with $IAP{\geq}20mmHg$ than in those with IAP <20 mmHg (16 vs. 5, p=0.049). The hospital mortality rate was 27.3%. Patients with a maximum $IAP{\geq}20mmHg$ exhibited significantly higher hospital mortality rates (p=0.006). Non-survivors had higher maximum and mean IAP values. Conclusions: Our results suggest that an elevated IAP may be associated with a poor prognosis in critically ill trauma patients.

• 대한한방내과학회지
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• 제40권3호
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• pp.312-330
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• 2019

Objectives: The present study aimed to provide clinical evidence on the effect of herbal medicine on the treatment of hepatitis C using a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: This study included RCTs that verified the effects of herbal medicine for the treatment of hepatitis C. A literature search of English, Chinese, and Korean databases was performed, and the selected literature was assessed to investigate the risk of bias. Results: The analysis included 14 RCTs. The total effective rate was the most commonly used outcome measure. The meta-analysis revealed that the total effective rate and total bilirubin difference were higher and that the recurrent rate was lower in the herbal medicine group than in the western medicine group (RR: 1.20, 95% CI: 1.06-1.35, p=0.003, I2=52; MD: 0.52, 95% CI: -0.62 to 1.66, p=0.37, I2=0; RR: 0.35, 95% CI: 0.11-1.09, p=0.07, I2=0). The included RCTs had relatively poor quality and a small sample size. Conclusion: Treatment with herbal medicine was found to be partially effective in treating hepatitis C. The included RCTs had relatively poor quality and a small sample size. This study can serve as a foundation for further clinical studies on the development of treatment methods for hepatitis C based on herbal medicine.

• 척추신경추나의학회지
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• 제14권1호
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• pp.119-134
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• 2019

Objectives : This study was conducted to investigate current research trends in Chuna manual therapy for the treatment of anxiety disorders in China. Methods : Using China Academic Journal and Pubmed, we performed a literature search of studies that were published from 2010 onwards. In total, 15 published studies were included in our analysis. Results : Of the 15 analyzed studies, nine were randomized controlled trials, two were non-randomized controlled trials, and four were case reports. Of the total patients, 80% were treated daily and received ${\leq}30$ treatments in total (excluding one study). In most studies(11 out of 15, 73.33%), the total effective rate of treatment was used to measure the outcome, with the Hamilton Anxiety Rating Scale being used most frequently. The case report demonstrated a therapeutic effect > 90%. In the control study, except for the two studies that reported significant improvement in the follow-up period, all of the measures were significantly improved (P<0.05) after treatment compared with before treatment. The An(按) and Rou(?) methods were the most frequently used. The Chuna method is categorized into four types: 1) It is performed around shoulders, neck, and face; 2) performed around abdomen, back, and neck; 3) performed on the whole body; 4) performed at the simply-stimulated acupoints. The most commonly used acupoint was Taiyang (Ex-HN 5), and the most frequently used acupoints were predominantly distributed in the head, face, and neck. Conclusions : This study demonstrated that Chuna manual therapy has significant effects when used as a treatment for anxiety disorder, warranting further investigation.

• 한국정보통신학회논문지
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• 제23권1호
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• pp.63-69
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• 2019

안와 내에서 안구의 상대적 위치는 여러 병적인 상태를 짐작할 수 있는 하나의 기준이 될 수 있다. 특히 안와골절, 갑상선 안질환, 안와 종양 등의 진단과 이에 약물 및 수술적 치료의 결과를 판단하는데 유용하다. 현재 안구 돌출 값을 측정하기 위해 주로 사용되는 대표적 측정 기기인 Hertel과 Naugle 안구돌출계 등은 검사자가 다를 경우, 같은 검사자가 반복적으로 측정하더라도 검사할 때마다 안와의 고정부위가 달라지는 현상, 또한 동일한 안구돌출계라고 하더라도 제조 회사가 다르다면 안와의 고정부위 디자인이 달라 검사자에 의한 측정 오차 발생이 필연적이다. 본 논문에서는 백색광 간섭계를 이용한 안구 돌출 측정 장치를 설계 및 제작하고 실제 사람의 안구 돌출을 측정하여 수동식 측정 방법에 비해 정밀도 및 반복 정도가 크게 높아진 것을 확인하였다.

• 한국문헌정보학회지
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• 제52권4호
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• pp.179-194
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• 2018

본 연구의 목적은 도서관의 성과를 측정하기 위해서 잠재성장모형을 적용하고 그 활용가능성을 논하는 것이다. 도서관의 성과를 측정하기 위하여 도서관 활동에 대한 데이터, 즉 이용자의 대출 데이터를 이용하였다. 시간에 따른 변화를 담고 있는 종단자료를 분석하기 위한 통계적인 모형으로 잠재성장모형을 이용하였다. 서울 소재 공공도서관의 2010년부터 2014년까지의 95,962명의 이용자의 대출데이터를 무조건모형, 조건모형, 혼합성장모형을 적용하여 대출의 특성을 분석하였다. 분석결과, 대출량은 절편요인이 4.19, 기울기요인이 0.24의 선형성장을 보였다. 성별에 따른 차이분석에서 큰 차이를 보이지 않았으나 4개의 그룹으로 나누었을 때, 10세 미만의 어린이의 대출 패턴이 급속히 증가하는 추세를 보였다. 향후 문헌정보학 분야에서 종단연구자료를 분석할 때, 잠재성장모형이 활용될 것으로 기대된다.

• 한방재활의학과학회지
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• 제29권3호
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• pp.61-74
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• 2019

Objectives This study aimed to review clinical studies about Korean medicine used in peroneal nerve palsy. Methods In 11 online databases (Earticle, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, KMbase, Korean Traditional Knowledge Portal, National Digital Science Library, MEDLINE/Pubmed, Ebscohost, Cochrane CENTRAL, EMBASE, China National Knowledge Infrastructure), we searched clinical studies about Korean medicine. Among the studies that we've searched, we excluded the studies that are not related to Korean medicine, case reports, randomized controlled trials and retrospective studies. As a result, 16 case studies and 1 randomized controlled trial are included. Results Total number of patients was 123. In these studies, acupuncture (100%), herbal medicine (58.8%), pharmacopuncture (58.8%), Korean physical therapy (58.8%), moxibustion (41.1%), cupping (41.1%) etc. were used. In acupuncture, GB34 and ST36 were most frequently used. Most of the herbal medicines used in these studies were different. Range of movement were most frequently used in outcome measure. Conclusions In this study, we reviewed studies about Korean medicine used in peroneal nerve palsy. It was difficult to clearly determine which intervention has improved the symptom. In the future, Further clinical studies will be needed to retain the evidence for the treatment of peroneal nerve palsy. And also more randomized controlled clinical trials to prove the efficacy of Korean medicine will be needed.

• 대한한방소아과학회지
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• 제33권3호
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• pp.82-102
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• 2019

Objectives The purpose of this study is to investigate clinical studies on the efficacy and safety of herbal medicine inhalation therapy in children by analyzing recent randomized controlled trials conducted in China. Methods We searched the clinical studies from the China Academic Journal (CAJ) in China National Knowledge Infrastructure (CNKI) using a by key word '霧化吸入' and specific criteria from 1st January 2010 to 2nd July 2019. Data regarding years of publication, demographic information, target diseases or symptoms, treatment methods, outcome measure, results and adverse events are collected for this study. Results Total of 44 randomized controlled trials were selected and analyzed. Respiratory diseases and symptoms (84.1%) were the most frequent target diseases that herbal medicine inhalation therapy was used. Acute stomatitis was another disease state that the therapy was used. In most of the studies, the herbal medicine inhalation in children showed significant efficacies. The most commonly used herbal medicines were Ephedrae Herba (麻黃), Lonicera Flos (金銀花), Armeniacae Semen (杏仁), Glycyrrhizae Radix et Rhizoma (甘草), Scutellaria Radix (黃芩), Forsythia Fructus (連翹) etc. Hardly any adverse effects were reported from the trials selected. Conclusions Based on the results of the clinical studies from China, herbal medicine inhalation therapy in children can be an effective and safe option for treatment and symptom improvement.

• 디지털융복합연구
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• 제17권4호
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• pp.211-217
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• 2019

국내 만성질환 관리에서 모바일 헬스 적용이 임상적으로 유용하다는 보고가 증가됨에 따라, 본 연구는 텍스트 마이닝 기법을 적용하여 국내 외 학술지에 게재된 국내 만성질환자 대상 모바일 헬스 중재연구의 특성 및 중심 키워드의 변화를 파악하고자 시도된 이차분석연구이다. 분석대상 논문은 2005년부터 2018년까지 학술지에 게재된 최종 20편으로, 추출한 텍스트는 Microsoft Excel을 활용하여 논문별 분석을 실시하였고, Text Analyzer를 사용하여 주제어를 추출하였다. 연구결과, 모바일 헬스 중재 연구는 고혈압, 당뇨병, 뇌졸중 관상동맥질환자에 주로 적용되었다. 가장 많이 사용된 중재 유형은 애플리케이션 개발이었으며, 최근 연구에서는 주로 '유용성', '모바일 헬스', '결과측정' 등의 단어들이 가장 많이 출현하였다. 추후 만성질환자 대상 모바일 헬스 중재에 관한 국내 외 연구 모두를 포함하여 주제어 간의 연관성을 확인할 수 있는 사회연결망 분석방법을 적용하여 그 효용성을 확인해볼 것을 제안한다.

• The Journal of Asian Finance, Economics and Business
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• 제8권9호
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• pp.273-285
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• 2021

This study estimates the financial value of return on investment (ROI) of research funds. Four simulation estimations are employed to measure ROI finance value that considers the outputs, outcomes, impacts and total ROI from the allocation input received. Research outputs, outcomes, and impacts can be quantitatively measured based on improvements to existing systems. In terms of input, the Malaysian government has allocated MYR301,350,000 for fundamental research in the 2021 budget compared with 2019, up 9.5 percent from 2019. It brings up the question: To what extent does the input of research funds allocated by the government yield a good return in outputs, outcomes, and impacts to the academic community, society, and country? The result of total ROI shows around MYR7 return is generated by researchers for each Malaysian ringgit channeled by the funder. More specifically, for a research project, it is more difficult to produce impacts and outcomes compared to research outputs. The positive return is evidence that all the allocated funds are beneficial to the stakeholders. The government can apply this approach in calculating ROI for evaluation and fund allocation to universities. Furthermore, the positive financial value of research output, outcome, and impact automatically contribute to a positive innovation environment in Malaysia.

• 대한한방소아과학회지
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• 제33권4호
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• pp.47-59
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• 2019

Objectives The purpose of this study is to analyze recent Chinese randomized controlled trials on efficacy and safety of the retention enema with herbal medicine in pediatric diarrhea. Methods We searched the recent Chinese randomized controlled trials from the China National Knowledge Infrastructure (CNKI) by using key words; '保留灌腸', '小兒', '腹瀉' and '泄瀉' with data range from January $1^{st}$, 2010 to March $2^{nd}$, 2019. Year of the publication, demographic information, disease, intervention, outcome measure, results, adverse events and composition of herbal medicine were analyzed for this study. Results 19 out of 32 studies were selected and analyzed. The most commonly used herbal medicine was Galgeungeumlyeon-tang modification (葛根芩連湯加減), and the most widely used retention enema method was to retain for 15 minutes and administer twice a day for 3 days. In most of the studies, retention enema with herbal medicine in pediatric diarrhea showed significant efficacies. No adverse effects were reported from the studies. Conclusions The results of these studies from China showed that the retention enema with herbal medicine in pediatric diarrhea may be effective and safe.