• Journal of Society of Preventive Korean Medicine
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• v.6 no.2
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• pp.112-127
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• 2002

Objectives: Younnyeniksoobulrodan(延年益壽不老丹) composed of Polygonum multiflorum THUNB. and some medical herbs is known as formula of senescence delay effect. The purpose of this study is to investigate the effect of Younnyeniksoobulrodan(延年益壽不老丹) on antioxidant enzyme activity such as Thiobarbituric acid reactive substance(TBARS), Superoxide dismutase(SOD), Catalase(CAT), Glutathione peroxidase (GSH-px) in rat erythrocytes and liver. Methods: Sprague-Dawley rats divided into 4 gorups, Young group(8 weeks old, N-8), Aging group(18 weeks old, N-18), pathologically induced aging gorup(injected D-galatose 50mg／kg, 1time／day for 6 weeks, CON) and Younnyeniksoobulrodan(延年益壽不老丹) administered group(D-galactose 50mg／kg and Younnyeniksoobulrodan extracts 840.0mg／kg 1time／day for 6 weeks, YIB). Rats were sacrificed and TBARS, SOD, CAT, and GSH-px were measured in rat erythrocytes and liver. Results: Plasma and liver TBARS concentrations of YIB group were significantly lower than those of control. Red blood cell(RBC) SOD activities of YIB group was increased(F=3.445, p=0.033, ANOVA test), and RBC catalase activities of all experimental group were not significantly different. RBC GSH-px activities of YIB group was increased(F=9.365,p=0.0001, ANOVA test). Liver SOD activities of YIB group was higher than those of control(F=4.967, p=0.008, ANOVA test). Liver catalase activities of all experimental group were not significantly different, and liver GSH-px activity of YIB group was significantly higher than that of control(F=3.846, p=0.022,ANOVA test). Conclusions: According to the above results, it is considered that Younnyeniksoobulrodan is effective in inhibiting lipid peroxidation and increasing antioxidative enzyme activities in D-galactose induced aging rat.

• Korean Journal of Oriental Medicine
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• v.3 no.1
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• pp.41-65
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• 1997

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analysing and differentiating of epidemic febrile disease - analysing and differentiating in accordance with the Sasang constitutional medicine baced on four-type recognition - differentiation of diease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance(-muscle born joint etc.) - standards for diagnosis of neuropsychiatric diease - standards for diagnosis of five sense organ diease - standards for diagnosis of external disease. The indivisual diagnosis pattern was arranged by the diagnostic requirments in the following odor : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattrrn, prognosis, a way of curing a diseases, prescription, herbs in common use, dieases appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirments in the following odor. another name, notion of diease, the main point of diagnosis, analysing and differentiating of disease, analysis of diease, discrimination of disease, prognosis, a way of curing and prescription of disease, dieases In western medicine appearing the disease in oriental medicine, documents.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.1
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• pp.121-126
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• 2020

In oriental medicine, it is rare to recommend the same herbal medicine to other patients because it is very effective in using a certain medicine for a patient with a certain disease. Because the same prescription works well for some people, but very bad results for some people. In order to solve this problem, we developed an algorithm that automatically recommends medicinal products when the patient biometric and Sasang constitution information are selected in the web program. Moreover, in this paper, it developed SWproducts to automatically determine the patients' constitution.

• Culinary science and hospitality research
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• v.22 no.6
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• pp.14-23
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• 2016

This purpose of this study is to examine the antioxidant and antimicrobial activities of Persicaria hydropiper L. extract in 70% ethanol and in water, a medicinal herb, as an effort to examine the potential of medicinal herbs for development of antioxidants and natural preservative substitutes. The total poly-phenol content in the 70% ethanol extract and in the water extract were 19.88 mg/g and 7.46 mg/g, respectively. The DPPH radical scavenging activity was 90.99% and 64.98% in the 70% ethanol extract and water extract, in which 70% ethanol extract showed a higher activity. The antioxidant effect of Persicaria hydropiper L. extract appears to be very good and due to its excellent growth inhibitory effect on food-poisoning-causing microorganisms in the food, it is thought to be utilized as a potential natural preservative substitute in many areas.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1562-1565
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• 2008

HCMCO5 is a herbal extract which comprises of eight different herbs. We studied whether this prescription has an acute toxicity in rats. SPF Sprague-Dawley male and female rats were administered orally with HMC05 extract of 2,000 mg/kg for 14days. We examined mortality, clinical signs, body weights and gross findings during the tests. The result showed no dead animals. We also could not find a significant body weight changes during the experimental period. In addition, no differences were found between control and HMC05 treated groups in clinical signs and other findings. These results indicate that HMC05 extract did not show any toxic effects, and oral ADL value was over 2,000 mg/kg in SD rats.

• Korean Journal of Pharmacognosy
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• v.24 no.2
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• pp.177-182
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• 1993

The pericarp of Cornus officinalis is well known famous medicinal drug in oriental countries. In this work, we have tried to evaluate the toxicity and also to find the lectin components from this seed. The lyophilized seed extract was lethal to experimental mouse at $250{\sim}300mg/kg$ and this toxic components were related to proteins. The lectins components were partially purified from the extract by ion exchange column chromatography. These lectins were relatively stable at temperature variations and also stable at pH $4{\sim}7$. The activity of these lectins did not inhibit by common carbohydrates molecules.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.5
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• pp.773-776
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• 2011

This study was focused on a certain clinical symptom, which could applicated by Pyeongwi-san, and the radical treatment. Pyeongwi-san is applicable to dampness retention in the spleen and stomach, accompanied by abdominal fullness, anorexia, nausea and regurgitation. Main action of Pyeongwi-san is to dry dampness, invigorate the spleen, promote the flow of gi, and regulate the stomach. The herbal remedy drying dampness like Pyeongwi-san however, is just indicatio symptomatica therefore radical treatment must be used together. Jeunginmaegchi, a medical book written by Gyeong-Myeong Jin, who was lived in Myeong dynasty. This book contains many clinical applicable symptoms and constituents derived from Pyeongwi-san. The herbal prescriptions composing Pyeongwi-san is composed of Changchul, Hubak, Jinpi, Gamcho. The major action of these herbs is drying dampness. Therefore, it shoud be seriously consider that curative therapy must eliminate the cause of endogenous dampness.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.5
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• pp.784-789
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• 2010

Syndrome of asthenia of spleen gi usually caused by improper diet, overstrain, emotional upsets, followed by syndrome of sinking of splenic gi. There are several pathologic categories of splenic gi deficiency syndrome. These include failure to nourish the body, failure to astringe liquid substances, failure of splenic gi to rise, gi stagnation in which gi can't disperse normally, failure of transportation. In the splenic gi deficient situation, body fluid is usually stagnated because the rest of the water absorbed from the food is transported to every part of the body by the action of splenic gi. In addition, there is abnormal sinking of clear gi, followed by fever due to gi deficiency. Bojungikgi-tang is composed of restoratives which are invigorating splenic gi and herbs which uplift splenic gi. It is mainly applicable to splenic gi deficiency syndrome accompanied by gi stagnation and fluid accumulation.

• The Journal of Korean Medicine
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• v.21 no.4
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• pp.260-263
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• 2000

This case study was performed to investigate the effects of Chongsimyonja-tang and Dong's acupuncture therapy on senile macular degeneration patient who has been treated in the Dong-Eui oriental hospital. A 57-year-old female with senile macular degeneration complained of headaches, heaviness of the ache, night sweat, dizziness. For a duration of 2 months, We prescribed Chongsimyonja-tang, and added 3-4 herbs according to the symtoms and also treated the patient with Dong s acupuncture therapy. After 2 months, the patient's eyesight improved ($0.2{\rightarrow}0.7$) and the headaches disappeared, as did heaviness of the ache, night sweat, and dizziness. In this case Chongsimyonja-tang and Dong's acupuncture therapy present valuable treatment of senile macular degeneration.

• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.77-86
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• 2013

Objectives Allergic purpura is frequent disease in children. The purpose of this study is to analyze traditional Chinese medicine treatments of Allergic purpura in children through traditional Chinese medical journal research. Methods 22 studies were selected based on title keyword "Allergic purpura" "Child" published in CAJ (China Academic Journal). The studies were about clinical effect, herbs, injections, treatments, and nursing in Allergic purpura in children. Results & Conclusions There are so many treatments studied on purpura in children based on CAJ. A Single or combination traditional Chinese medicine treatment is effective in Allergic purpura in children. Therefore, we need to study more about Allergic purpura in children and should make more clinical cases about it.