• 한국식품영양학회지
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• 제21권2호
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• pp.210-217
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• 2008

This study evaluated the hypolipidemic effects of Eleutherococcus senticosus combined with several oriental medicinal herbs. In addition, it addressed whether consuming a diet of healthy food along with a daily supplement of this composite could affect the health status of individuals suffering from diet-related disease such as obesity and hyperlipidemia. The effects of the combined medicinal herbal extracts(MHE) extracted with hot water on reducing serum lipids and improving blood parameters were examined in rats fed a high-fat diet for 5 weeks. Sprague-Dawley rats were randomly assigned to 4 groups: basal diet only(BDG), high fat diet without MHE(FCG), high fat diet and 10% MHE(F10E) and high fat diet and 20% MHE(F20E). Serum lipid contents and blood variables were examined after the experimental period. The results of were as follows. The hematological data for the 4 groups were similar indicating no significant differences. There were moderate level of serum GOT activity in the F10E and F20E groups as compared to the FCG group. Total cholesterol, LDL-cholesterol, triglyceride in serum and the atherogenic index were remarkably reduced in the MHE-supplemented groups as compared to the control group. However, F10E and F20E groups had significantly higher HDL-cholesterol levels than the control group. These results imply that combination of several medicinal herbal extracts could be used to reduce of serum lipid concentrations. The data from this study will be used as basic information with the field of functional food research to address how we can apply oriental medicinal resources to foods. Such research currently drawing considerable attention world-wide.

• 동의생리병리학회지
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• 제21권3호
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• pp.596-604
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• 2007

For countless time, many have been made in our oriental medicine. To understand such prescription and to use, we must study the monarch(jun), minister(chen), adjuvant(zou) and guide(shi) theory that is most of the prescription structure principle's the basis. The monarch is the center of the prescription. Two kind is greatly in the method to select the monarch, in the prescription. One method is that a medicinal herb of the high class of medical herb of the Sinnong's Classic becomes the monarch, and the other method is a medicinal herbs which there is most many qunantity in the prescription becomes the monarch. Additionally, a medicinal herbs name of a prescription name can become the monarch. The minister assist the monarch and this is a criteria of the prescription grouping with the monarch. The minister has close relation with the monarch. The adjuvant helps the monarch and the minister nature of drug or restains. So this makes the prescription effectiveness act accurately. The guide does the activity to help the harmony of the prescription and the activity to help the prescription to act in correct place. If we understand the monarch, minister, adjuvant and guide theory well, we have some advantage. The interpreting of the prescription comes to De easy. and, an application range of the prescription is enhanced. the increase and decrease of the medicinal herbs comes to be easy in the prescription. Finally that theory will be used for the principle to make new prescription.

• 생명과학회지
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• 제20권6호
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• pp.922-928
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• 2010

한방 생약재로부터 안전하면서도 신규의 항혈전제를 개발하기 위해, 현재 국내에서 유통되고 있는 국내 및 국외산 한방 생약재 33종을 대상으로 40종의 에탄올 추출물을 조제하고, 이들의 thrombin time (TT), prothrombin time (PT), activated partial thromboplastin time (aPTT)을 평가하였다. 생약재중 중국산은 28종으로 대부분이 국외산이었으며, 부위별로는 종자 및 뿌리 부위가 19종을 차지하였다. 평균 수분함량은 $6.85{\pm}2.26%$, 평균 추출율은 $5.27{\pm}4.25%$를 나타내었다. 조제된 시료의 TT평가 결과, 사인(중국), 고본, 팔각향, 계지, 당삼, 계혈등, 행인, 오배자, 괄루근 및 포황에서 우수한 트롬빈 저해활성을 확인하였으며, 다양한 농도에서 평가 결과 계혈등, 행인, 팔각향, 계지, 오배자 추출물 순으로 트롬빈 저해능이 강력함을 확인하였다. PT 평가 결과 오배자, 계혈등, 행인에서, aPTT 평가결과 오배자 및 계혈등에서 우수한 항혈전능을 확인하였다. 한편 추출물의 인간적혈구 용혈활성을 평가한 결과, 계혈등, 팔각향, 계지, 오배자 추출물은 $500\;{\mu}g/ml$ 농도에서도 용혈활성이 없음을 확인하여 이들 4종을 최종 선정하였다. 본 연구결과는 이미 대량생산이 확립된 한방생약제로부터 우수한 항혈전제 개발이 가능함을 제시하고 있으며, 트롬빈 및 혈장 응고 인자에 대한 특이 저해제 개발이 가능함을 제시하고 있다.

• 대한한방소아과학회지
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• 제24권2호
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• pp.59-74
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• 2010

Objectives The purpose of this study is to analyzing clinical trials of the current acupoint sticking treatment on Sambok* to prevent winter diseases through summer prophylactic treatment. Methods 33 Chinese clinical studies published in last fifteen years were selected for analysis. Results Acupoint sticking treatment on Sambok* is used in asthma, rhinitis, bronchitis. Commonly used herbs are Sinapis Semen(白芥子), Asari Herba Cum Radix(細辛), Euphorbiae Kansui Radix(甘遂), Corydalis Tuber(玄胡索), Moschi Moschus(麝香), Ephedrae Herba(麻黃), Cinnamomi Cortex Spissus(肉桂) and Commonly used acupoints are Feishu(肺兪), Kohwang(膏肓), Shinsu(腎兪), Pisu(脾兪). 33 studies showed that the effect of treatment in different age, symptom, acupoints, herbs, methods. However, it shows that acupoint sticking treatment on Sambok* is effective in various diseases, especially in respiratory disease. Conclusions This study shows that acupoint sticking treatment on Sambok* is effective in preventing many diseases. More clinical studies about acupoint sticking treatment and standardizations to evaluate effectiveness are needed to prove its efficacy clearly.

• 대한한의학원전학회지
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• 제24권2호
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• pp.109-149
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• 2011

Objectives : The study contains formulas, medicinal herbs, how to make of paste preparations in "Dongeuibogam". Methods : I will try to find paste preparations in "Dongeuibogam" using a word, paste(膏). Results : Paste preparations are categorized into two types: the external and the internal medicine. Paste preparations were used not only in the dermatology disease but in the internal disease. The same formula name to have different information was written by other people. Various kinds of medicinal herbs, minerals, animals were used and type of oil or juice was used to dissolve these. Methods to process paste preparations were to grind medicines or extract from medicinal materials. Paste preparations for the external was used to put in eyes or to push into wound and apply them to the skin. Paste preparations for the internal was used to take with wine, water and herbal tea. Some paste preparations were used both external and internal. Conclusion : These results explain that Paste preparations were variously used in "Dongeuibogam".

• Korean Journal of Acupuncture
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• 제28권4호
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• pp.137-145
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• 2011

Objectives : This research dealt with the content of the hot medicinal compress technique in Donguibogam in order to develope the hot medicinal compress technique as a new therapy technique. Methods : In this research, we searched for the hot medicinal compress treatment in Donguibogam. Results : The hot medicinal compress technique mainly cures the diseases on the body surface and it can be applied to digestive troubles and gynecologic diseases. The hot medicinal compress technique is operated mainly at wound around the affected parts and it is applied to the constitutional symptom at the abdominal region. In the hot medicinal compress technique was used much more with medication, and the herbs used in the treatment consists of hot tastes and the warm characteristics. In the hot medicinal compress method with direct heating the herbs was mainly used. Conclusions : The hot medicinal compress technique is considered as treatment which can be utilized easily and it can be used an easy and useful self-treatment.

• 대한한의학회지
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• 제21권2호
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• pp.14-24
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• 2000

Objectives : To direct methods of management and development of herbs and their derived products, and at the end of this study to inform the process of making new herbal drug regulations in Korea. Methods : This study analyzed the regulations and laws of western medicine drugs. Results : We have got some herbal prescriptions which are not in the eleven books of oriental medicine now in use but which have proved effective. We need to establish standards for permissions to produce medical products through those prescriptions. Besides, we need the special permissions to produce herbal products through prescriptions, especially those which have been used to treat incurable diseases. And, we can contribute to globalization of oriental medicine and to well situating of herb products and medicinal acupunctures if we produce them according to international standards. It is thought that herbal medicine has no side effect in the medical society in Korea. But, it is getting popular to administer herbal medicine and western medicine together. Thus, the side effects of taking both medicines at the same time should be documented. Conclusions : Herbal medicines and herbal products should be under the control over the whole process of production, circulation, and sales. Now, it is time for herbal medicine to be known to all over the world. Therefore, herbal medicine must meet and adhere to the standards set by the western society and WHO.

• 한방안이비인후피부과학회지
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• 제27권4호
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• pp.87-100
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• 2014

Objectives : This study is aimed to analyse immunohistochemical research trend on psoriasis and consider the results in terms of Korean medicine. Methods : We analyse both immunohistochemical research papers and Korean medical papers on psoriasis, which I searched using KISS(Korean studies Information Service System) and OASIS(Oriental Medicine Advanced Searching Integrated System). Results : Psoriasis is characterized by hyperporliferation of the epidermis, inflammatory cell accumulation and increased tortuosity and dilatation of dermal papillary blood vessels. Recently, angiogenesis is considered to play a major role in pathogenesis of psoriasis. Conclusion : In Korean medicine, blood-tonifying, blood-cooling and blood-activating medicinal herbs have generally been used to treat psoriasis. I consider these herbs which also treat vessel problem can have an effect on angiogenesis of psoriasis.

• 동아시아식생활학회지
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• 제16권2호
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• pp.136-144
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• 2006

This research evaluated how the composition of Yak-sun(oriental diet therapy), taken as a nutritional supplement with daily meals, can effect the medical condition of those suffering from modern diseases like obesity and hyperlipideia. We produced Yak-sun tea, determined its nutrient composition and physical characteristics and evaluated how this tea effects affects the active oxygen concentration inside the body by clinical practices. The study results indicated that this tea significantly decrease active oxygen concentration. We think that scientific and objective evaluation was done on the components of Yak-sun tea prescription. We concluded that we could apply the components not only in the form of tea, but also in other food forms. The information we received from this conclusion will provide basic information for the application of oriental medicinal resources into other foods and will also be a steppingstone in the field of functional food research for the development of medicinal herbs which is already an important research field world-wide.

• 사상체질의학회지
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• 제14권1호
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• pp.1-9
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• 2002

We analyzed 44 and 16 types of herbal medicines for Taeumin and Taeyangin, clinically applied in Dongyisoosebowon. In order to discover the standard of herbal classification for the Sasang constitutions, four concepts of Sasang Medicine were applied. These included 'Sadangron (theory of four groups)', 'Seungganggaehap (ascending-descending and gathering-dispersing)', 'Pyorihanyoul (exterior-interior and hot-cold)',and 'Hyungchiaekmi (fragrance, smell, bodily fluid and taste)'. According to these analyzing methods of herbal properties, we have reached the following conclusions: Herbal medicines for 'Taeumin' are characterized by opening energetics that reinforce dispersing Qi. The 'Exterior cold disease' is treated with herbs that ventilate the lungs and disperse dampness in three ways: by moistening the lungs, by releasing exterior, and by resolving dampness. The 'Interior heat disease' is treated with herbs that clear the liver and disperse heat in two ways. One by clearing liver heat through dispersing damp-heat of the small intestine and the other by opening orifices. Herbal medicines for Taeyangin are characterized by those that gather energy inward. They include herbs that treat beriberi, dystrophy of the extremities and vomiting, as well as, fish, shellfish, fruits and vegetable.