The Korean Journal of Food And Nutrition (한국식품영양학회지)

The Korean Society of Food and Nutrition (한국식품영양학회)
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Effects of Eleutherococcus senticosus and Several Oriental Medicinal Herbs Extracts on Serum Lipid Concentrations

가시오가피와 수종 한약자원 혼합 조성물이 고지방 식이에 있어 혈청 지질농도에 미치는 효과

  • Choi, Hua-Shan (College of Nursing, Yanbain University) ;
  • Kim, Yeung-Hee (School of Nutrition Hotel Culinary Art, Anyang Technical College) ;
  • Han, Jong-Hyun (Dept. Herbal Resources, Professional Graduate of Oriental Medicine, Wonkwang University) ;
  • Park, Sung-Hye (Dept. Health Care, Wonkwang Digital University)
  • 최화선 (연변대학교 간호학원) ;
  • 김영희 (안양과학대학 호텔조리영양학부 식품영양전공) ;
  • 한종현 (원광대학교 한의학전문대학원) ;
  • 박성혜 (원광디지털대학교 한방건강학과)
  • Published : 2008.06.30
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Abstract

This study evaluated the hypolipidemic effects of Eleutherococcus senticosus combined with several oriental medicinal herbs. In addition, it addressed whether consuming a diet of healthy food along with a daily supplement of this composite could affect the health status of individuals suffering from diet-related disease such as obesity and hyperlipidemia. The effects of the combined medicinal herbal extracts(MHE) extracted with hot water on reducing serum lipids and improving blood parameters were examined in rats fed a high-fat diet for 5 weeks. Sprague-Dawley rats were randomly assigned to 4 groups: basal diet only(BDG), high fat diet without MHE(FCG), high fat diet and 10% MHE(F10E) and high fat diet and 20% MHE(F20E). Serum lipid contents and blood variables were examined after the experimental period. The results of were as follows. The hematological data for the 4 groups were similar indicating no significant differences. There were moderate level of serum GOT activity in the F10E and F20E groups as compared to the FCG group. Total cholesterol, LDL-cholesterol, triglyceride in serum and the atherogenic index were remarkably reduced in the MHE-supplemented groups as compared to the control group. However, F10E and F20E groups had significantly higher HDL-cholesterol levels than the control group. These results imply that combination of several medicinal herbal extracts could be used to reduce of serum lipid concentrations. The data from this study will be used as basic information with the field of functional food research to address how we can apply oriental medicinal resources to foods. Such research currently drawing considerable attention world-wide.

Keywords

References

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