• Advances in Traditional Medicine
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• v.7 no.5
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• pp.501-508
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• 2008

Anti-nociceptive and anti-inflammatory effects of Clematidis Radix (CR)-distillates were investigated in three different pain animal models. Highly purified distillate of CR was injected to Zusanli (ST36) acupoint, called CR herb-acupuncture in the Korean traditional medicine. In tail flick latency test, the CR herb-acupuncture treatment did not show a significant effect of relieving acute phasic pain. To investigate the anti-inflammatory effect of CR herb-acupuncture, inflammatory pain was induced by subcutaneous injection of formalin to the plantar tissue or intra-articular injection of carrageenan to the tibio-tarsal joint in the rats. And the medicinal effect of CR herb-acupuncture was evaluated by analyzing pain behavior such as licking or biting behavior, or by measuring weight distribution ratio between two foot and ankle circumference. In the rat formalin test, the analgesic effect of CR herb-acupuncture was more pronounced in the late phase (for 20 min after the early phase) than in the early phase (for the first 10 min post formalin injection). It also significantly alleviated the carrageenan-induced monoarthritis, in terms of weight distribution ratio and ankle edema. These results revealed that CR herb-acupuncture was effective to treat the inflammatory pain and could be used as an analgesic treatment with an antiinflammatory effect.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.4
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• pp.25-42
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• 2014

Objectives: To observe the effects of Herb medication on Polycystic Ovary (PCO) in rats. Methods: Riss (Research Information Sharing Service) was searched for Oriental medicine about PCO on 2000~2014. So, Experimental studies using PCO model induced by Estradiol Valerate (EV) was selected to analyze how effects they were. Consequently, 10 studies published on 2000~2014 were selected to analyze about weight of model and both ovaries, the number aries, the number of follicle and corpus of follicle and corpus luteum, the level of serum Androstenedione (ADD) and total estrogen, the level of Nerve Growth Factor (NGF) and Corticotropin Releasing Factor (CRF), the crossover rate and the number of implantation. Results: Among them, there was significantly difference between treatment group and control group in weight of both ovaries, the number of follicle and corpora lutea, the crossover rate and the number of implantation. Conclusions: The effects of Herb medication was observed on making weight of ovaries with PCO to promote. The study about effect of Herb medication on NGF and CRF with PCOS had to be conducted. The further research have to focus on treatment of subfertility and infertility, that is field showing the advantage of Oriental medicine.

• Journal of Oriental Neuropsychiatry
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• v.20 no.1
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• pp.89-106
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• 2009

Objectives : The purpose of this study is to analysis of the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun". Methods : The herb medications of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong(上.中.下統) and "Enlargement side prescriptions" (增補方) are selected by comment on the chief virtue including reference word of corresponded with neuropsychiatry. Results and Conclusion : "Bang-Yak-Hap-Pyun" is a book most people who have a background or career in Han Medicine(韓醫學) would pore over. They corresponded with neuropsychiatry among the herb medications of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong(上.中.下統) are 55 prescriptions that Sang-Tong(上統) is 8 prescriptions, Jung-Tong(中.統) is 23 prescriptions and Ha-Tong(下統) is 24 prescriptions. And the herb medications corresponded with neuropsychiatry of "Enlargement side prescriptions" (增補方) are 40 prescriptions. And then the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun" received much influence from "Dong-Eui-Bo-Gam". Incidentally the herb medications corresponded with neuropsychiatry of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong showed the high percentage in Neurosis. And the herb medications corresponded with neuropsychiatry of "Enlargement side prescriptions" showed the high percentage in Psychosis. Besides not only put "Enlargement side prescriptions a premium on "Dong-Eui-Bo-Gam", but also made it the herb medications which were recorded on books flowed after "Dong-Eui-Bo-Gam" known. It was entered up books quoted from "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong but the herb medications were that were not succeeded from "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong. Therefore "Enlargement side prescriptions" shows the efforts for supplement of "Bang-Yak-Hap-Pyun" Sang.Jung.Ha-Tong.

• Herbal Formula Science
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• v.10 no.2
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• pp.47-55
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• 2002

In Oriental medicine, So-gal(消渴) is similar to Diabetes Mellitus in the symptoms. In the medical treatment of So-gal(消渴), one kind of herb medicine is recorded in ancent medicine literatures. That herb medicine is a juice of vegetable drunken with herb medicine of So-gal(消渴). Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁), sang-gang-jup(生薑汁) etc. is that. In that juices, Milk(牛乳汁), human milk(人乳汁), gam-ja-jup(甘蔗汁), wo-jul-jup(藕節汁), li-jup(梨汁) have sweety tastes, and cold nature. So they cure So-gal(消渴) come from dry and hot nature. Sang-gang-jup(生薑汁) is different with others in the taste and nature that sweety and hot taste and hot nature. Sang-gang-jup(生薑汁) cure the sequela of So-gal(消渴) by his hot nature. We think In Diabetes Mellitus, that juice can be used by drink for the treatment of diet because of simility between So-gal(消渴) and DM.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.558-562
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• 2011

Women are very weak and liable to various disease in postpartum. So postpartum care is very important. The two patient who was diagnosed with postpartum disease was traeated and improve. We thought that their symptoms was deficiency of Qi. The two patient was treated by herb medicine, acupuncture and moxibustion. Their symptoms was disappeared. After the oriental medical treament, the postpartum disease differentiated deficiency of Qi was improved. The oriental medical treament(herb medicine, acupuncture and moxibustion) relieves postpartum disease with Postpartum Sweating.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.1-8
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• 2004

Objectives: The prostatitis is characterized as relatively uncurable chronic recurrent illness. Because it is so difficult to treat, this study was designed to evaluate the clinical effects of herb medicine, acupuncture, and herbal acupuncture therapy on chronic prostatitis. Methods: A clinical observation was made on thirty patients with chronic prostatitis. They were treated with herb medicine, acupuncture, and herbal acupuncture therapy. Before and after treatment we measured NIH-CPSI(National Institutes of Health Chronic Prostatitis Symptom Index). Results: After treatment NIH-CPSI was decreased considerably. Conclusions: This suggests a role for oriental medical therapy in treating prostatic diseases. Further study into approach and application of these treatments for prostatitis is needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.389-397
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• 2011

This study tried to integrate the traditional oriental medical theories and results of experimental studies of herbaceous plants on anti-diabetes. And I tried to analyze recent experimental study trend on the anti-diabetic herb. I searched anti-diabetic herb studies on 4 korean databases and 10 korean journals by keywords, 'diabetes', 'blood glucose', 'glycometabolism', 'pancreatic ${\beta}$-cell', etc. In order to see detail review, searching was performed from 2000 to 2010. And I searched 125 study cases concerning anti-diabetic herb and 72 varieties herbaceous plants used in study of anti-diabetes. and I analyzed the choice motives of each herb for anti-diabetic study, the extract methods and anti-diabetic evaluation contents. And I analyzed anti-diabetic herbs from a traditional oriental medical point of view. When the researchers chose herb for anti-diabetic experiment, just 8.8% of the choice was based on the oriental medical evidences. I found that 60.6% of the herb shown to be effective in diabetes experimentally had oriental medical theory-based Properties(性). There were studies with whole plants(16.8%), aqueous extract(45.6%), methanol extract(8.0%), ethanol extract(8.0%) and comparative studies of more than 2 types of extracts or various fractions(18.4%). The most frequent experimental diabetic models was diabetic mouse induced by streptozotocin(STZ)(87.8%). And there were db/db mouse(6.7%), ob/ob mouse(1.1%), etc. 33.6% of all studies just measured hematological indices of diabetes, and 66.4% researches analyzed details. To improve herbaceous plants study on diabetes, we oriental medical scientists have to integrate the oriental medical theories and results of experimental studies.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.242-249
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• 2005

Purpose : The purpose of this paper is to report the effect of oriental medicine to primary infertility caused by uterus unicornis. Methods : The patient in this case, 30 years-old female was treated with herb medication(Sosihotang, Gyejibokryeonghwan) for one month. Before oriental treatment, she had been diagnosed as primary infertility caused by uterus unicornis in Samsung Cheil Hospital and treated medication and injection for IUI(intrauterine insemination) in 2 times. But she had failed in gestation. Results : After taking herb medication she became pregnant. Conclusion : According to this result, we concluded that herb medication could improve fertility rate. After this paper, further study and clinical approach based on oriental medicine will be needed about infertility caused by uterus unicornis.

• The Journal of Korean Medicine
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• v.18 no.2
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• pp.326-339
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• 1997

The Background and Purpose : Many herb-medicines are frequently used in China but they are not in Korea. It is required to prove them worthy to introduce into Korea and to find substitutes for them. The Objective and Methods : During stay in China as a Professor extraordinary, I investigated applications of Chinese modicines, books and theses. The Results and Conclusions : 1. In China the cheap herb-medicines are chosen preferentially and the classic rules of oriental medicine are truly observed. 2. in China it is impossible to prove virtue of ready made herb-medicines because constituents are not opened. 3. Commonly used herb-medicines are drug of clean away heat(淸熱藥) which are antinflammatories or anti-toxins. 4. Antitumorigenic effects was frequently reported but they don't get complete agreement also in China. 5. Herb-medicines which are frequently used in China but not in Korea have no significant differences from commonly used herb-medicines in Korea.

• The Journal of Internal Korean Medicine
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• v.30 no.1
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• pp.249-255
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• 2009

Currently, drug-induced liver injury (DILl) has been reported to be common cause of acute hepatitis, and oriental medicine and folk remedies are no exception. However, because many studies about DILl have been reported by western medical society. they has taken the initiative of DILl not only for western drugs but also herbs. So, academia of oriental medicine should make an effort to progress herb-related DILl studies. We describe a patient of acute liver injury which had been caused by comfrey, albizzia julibrissin, ulmus davidiana var. japonica, red ginseng. We hope that this report helps for studying the diagnosis and management of herb-derived DILl. and for establishing a standard of oriental therapy to DILL.