• 지식경영연구
• /
• 제19권3호
• /
• pp.89-112
• /
• 2018

Under exhibition circumstances, exhibition advertising by organizer is a mean to promote exhibition service to exhibitors and visitors while general advertising is to promote products and services to consumers. The objective of this research is to suggest advertising strategies by seeing differences in the impact of information quality and media credibility on visitor intention depending on the types of exhibition. This study adopted Elaboration Likelihood Model to measure the impact of central and peripheral cues on advertising attitude and its consequence on visitor intention. We further examined how these influence processes were moderated by exhibition types of B2B and B2C. We conducted survey from B2B and B2C exhibitions respectively, and analyzed structural equation model and moderator regression. We found that first, among factors of information quality as a central cue, argument strength has a positive impact on attitude towards advertising. Second, we also found among factors of media credibility as a peripheral cue, media trustworthiness has a positive impact on attitude towards advertising. Lastly, this study revealed that a type of exhibition moderates the central and peripheral routes towards advertising attitude, showing that B2C visitors are influenced by factors of information quality, and B2B visitors rather by media credibility. This study yields implications in that it gives marketers of organizer a background to set different marketing strategies depending on the types of exhibition.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권18호
• /
• pp.8155-8161
• /
• 2016

The prognostic significance of AgNOR proteins in stage II-III rectal cancers treated with chemoradiotherapy was evaluated. Silver staining was applied to the $3{\mu}m$ sections of parafin blocked tissues from 30 rectal cancer patients who received 5-FU based chemoradiotherapy from May 2003 to June 2006. The microscopic displays of the cells were transferred into the computer via a video camera. AgNOR area (nucleolus organizer region area) and nucleus area values were determined as a nucleolus organizer regions area/total nucleus area (NORa/TNa). The mean NORa/TNa value was found to be $9.02{\pm}3.68$. The overall survival and disease free survival in the high NORa/TNa (>9.02) patients were 52.2 months and 39.4 months respectively, as compared to 100.7 months and 98.4 months in the low NORa/TNa (<9.02) cases. (p<0.001 and p<0.001 respectively). In addition, the prognosis in the high NORa/TNa patients was worse than low NORa/TNa patients (p<0.05). In terms of overall survival and disease-free survival, a statistically significant negative correlation was found with the value of NORa/TNa in the correlations tests. Cox regression analyses demostrated that overall survival and disease-free survival were associated with lymph node status (negative or positive) and the NORa/TNa value. We suggest that two-dimensional AgNOR evaluation may be a safe and usable parameter for prognosis and an indicator of cell proliferation instead of AgNOR dots.

• 대한의생명과학회지
• /
• 제10권4호
• /
• pp.361-366
• /
• 2004

The purpose of this study was to determine the effect of high voltage pulsed current (HVPC) stimulation on proliferative activities of basal keratinocytes by measured nucleolar organizer region (NOR) expression and thickness of spinous layer in aged rat skin. Fifty-one weeks old twelve male Sprague-Dawley rats (300∼350g) were divided into control and HVPC stimulation groups. Each animal's hair on the back were removed. The HVPC stimulation group received an negative monophasic twin peak pulsed current stimulation with 50 V, while the control group was given the same treatment without electricity. The rats were sacrificed after 3 weeks. The biopsy specimens were fixed in formalin, embedded in paraffin and stained with hematoxyline-eosin and silver nitrate. The thickness of basal to granular layer of the epidennis were measured using a light microscope and computerized image analysis system. The number of argyrophilic nucleolar organizer region (AgNOR) were counted using a light microscope and computerized image analysis system and calculated as the mean number of AgNOR per nucleus in the basal keratinocyte. By using a Student's t-test, an increase in the thickness of basal-spinous layer (P<0.001) of epidermis can be observed in HVPC stimulation rats as compared with the control rats, whereas the thickness of the granular layer is not affected. A Student's t-test showed a significantly higher mean NOR number per nucleus of the basal keratinocyte in the HVPC stimulation rats than control rats (P<0.001). There was significantly positive correlation between the NOR number and the thickness of basal-spinous layer (r=0.80, P<0.05). These results suggest that the HVPC stimulation may increase the thickness of spinous layer in the epidennis due to increased proliferative activities of basal keratinocytes in epidennis in aged rat skin.

• 생명과학회지
• /
• 제12권5호
• /
• pp.605-609
• /
• 2002

개의 염색체수는 2n=78이며 염색체의 형태를 보면 submetacentric chromosome metacentric chromosome인 X와 Y를 제외하고 모든 상염색체가 acrocentric chromosome이며 그 크기가 작고 크기의 차이가 나지 않는 염색체들이 많아 G-banding등에 의한 핵형의 표준화가 완전하게 이루어지고 있지 않다. 본 연구fl서는 G-banding high-resolution-banding NOR- banding등의 방법을 이용하여 개의 미소 염색체들에 대한 핵형 및 염색체 동정을 하고자 하였다. C-banding과 high-resolution banding에 의한 그 결과 아직 표준화가 되어 있지 않은 염색체 중 34번, 37번 등의 염색체에서 본 연구 결과가 차이가 있었으나 이는 해석상의 차이로 보이며 NOR-banding에 의한 분석결과 Y염색체와 3쌍의 상염색체에서 존재함을 확인 할 수 있었고 이는 개의 염색체 동정의 지표로 활용할 수 있으리라고 생각된다.

• 생명과학회지
• /
• 제17권2호통권82호
• /
• pp.192-197
• /
• 2007

외부 병원체 침입으로 이동하고 있는 T 세포는 두가지 뚜렷한 형태적인 변화, 즉, leading edge와 uropod를 형성하여 효과적으로 T세포 이동에 영향을 미친다. Uropod 구조물은 이동하는 림프구들의 뒤쪽에서 관찰 할 수 있는 아주 독특한 구조로 CD44, ERM, F-actin과 같은 단백질들이 서로 영향을 미치며 모인다. F-actin cytoskeleton은 세포의 형태를 유지하는 기본적인 틀을 제공한다. Rho A small GTPase는 이러한 cytoskeleton을 재구성하는 organizer로 역할을 한다고 보고되어 왔다. 지금까지, 다양한 경로를 통하여 Rho A가 활성화 되어 진다고 보고 되었다. 본 실험에서 PDZ 도메인이 세포 내부 RHo A에 GDP가 결합된 불활성화 형태의 Rho A를 GTP가 결합된 활성화 형태로 전환한다는 것을 알았고, F-actin cytoskeleton을 재구성 하며, PDZ 도메인을 함유한 세포는 uorpod 구조물이 없어졌으며 세포 이동 속도도 감소하는 것을 알았다. 따라서 Rho A와 F-actin cytoskeleton 사이의 신호 전달 과정이 uropod 형성에 아주 중요한 기능을 할 것이라는 것을 알았다.

• 한국언론정보학보
• /
• 제33권
• /
• pp.253-285
• /
• 2006

본고는 개별 시민들이 일상생활 속에서 체감하는 문제들을 네트 상에서 제기하고 동일한 이해를 갖는 시민들이 자발적으로 참여하여 조직되는 개인 차원의 온라인 시민 사회운동에 관심을 갖고 안티닉스 운동을 사례로 삼아 운동의 공론화는 누가 어떤 과정으로, 어떻게 진행했으며, 어떤 결과를 낳았는가와 안티닉스 운동의 공론화 과정에서 형성되는 담론의 특징은 무엇인가를 분석해 보았다. 연구 결과 안티닉스 운동은 사이트 운영자와 그를 따르는 적극적 참여자에 의해 주도된 것으로 나타났다. 또한 운동 전반에 걸쳐 사이트 운영자의 다양한 운동 전략이 사이트 방문자들의 적극적 참여를 유도하는 안티닉스 운동의 성공요인임을 확인할 수 있었다. 또한, 안티닉스 운동 게시판의 공론장은 익명성을 바탕으로 욕설과 비방이 주를 이루기보다는 전통적 공론장의 기능과 역할에 가깝다는 점을 발견할 수 있었다. 또한 일시적으로 난장의 요소가 지나쳐 공론장의 기능을 약화시키는 경우, 이를 견제하는 이성적인 참여자들이 등장하는 것을 발견할 수 있었다. 또한, 게시판 운영자의 전략적이며 효과적인 대응 역시 안티닉스 운동의 공론장이 전통적인 공론장에 가깝게 기능할 수 있도록 돕는 데 중요한 요소로 작용하고 있음을 확인 할 수 있었다.

• Molecules and Cells
• /
• 제44권10호
• /
• pp.723-735
• /
• 2021

Spemann organizer is a center of dorsal mesoderm and itself retains the mesoderm character, but it has a stimulatory role for neighboring ectoderm cells in becoming neuroectoderm in gastrula embryos. Goosecoid (Gsc) overexpression in ventral region promotes secondary axis formation including neural tissues, but the role of gsc in neural specification could be indirect. We examined the neural inhibitory and stimulatory roles of gsc in the same cell and neighboring cells contexts. In the animal cap explant system, Gsc overexpression inhibited expression of neural specific genes including foxd4l1.1, zic3, ncam, and neurod. Genome-wide chromatin immunoprecipitation sequencing (ChIP-seq) and promoter analysis of early neural genes of foxd4l1.1 and zic3 were performed to show that the neural inhibitory mode of gsc was direct. Site-directed mutagenesis and serially deleted construct studies of foxd4l1.1 promoter revealed that Gsc directly binds within the foxd4l1.1 promoter to repress its expression. Conjugation assay of animal cap explants was also performed to demonstrate an indirect neural stimulatory role for gsc. The genes for secretory molecules, Chordin and Noggin, were up-regulated in gsc injected cells with the neural fate only achieved in gsc uninjected neighboring cells. These experiments suggested that gsc regulates neuroectoderm formation negatively when expressed in the same cell and positively in neighboring cells via soluble factors. One is a direct suppressive circuit of neural genes in gsc expressing mesoderm cells and the other is an indirect stimulatory circuit for neurogenesis in neighboring ectoderm cells via secreted BMP antagonizers.

• Journal of Construction Engineering and Project Management
• /
• 제4권2호
• /
• pp.8-11
• /
• 2014

The interactions and interrelationships between stakeholders largely determine the overall performance of a construction project, and have the crucial responsibility for delivering a project to successful completion. An important component of stakeholder management is stakeholder analysis. Two case studies are conducted within Kerala (India). The main objective was to carry out stakeholder analysis using stakeholder organiser deluxe software, considering the data's collected from the project execution team using questionnaire. During data collection the key stakeholders were identified, to know how to manage them, their interest, power, attitude level etc, for quality improvement. Analyze the results using the software Stakeholder organizer deluxe and modeling of stakeholders is to be done. Finally validate the models of the projects. These findings may mainly reflect the stakeholder management environment in the respective regions of project implementation.

• 한국전자거래학회지
• /
• 제6권1호
• /
• pp.69-81
• /
• 2001

No organization can survive in today's modern society of information and high technology without internet and/or intranet. International convention industry is one of many high-technology dependent fields today which have started gathering new attention since the new millennium had begun. According to our survey, no professional convention organizer has used so far any type of integrated information system which is the vital source of support of the convention industry. Only the general purpose office softwares have been in use. The main purpose of this study is to design a model for ICIMS(International Convention Information Management System) to manage all the related information of international convention in a systematic and integrated way and to implement its prototype. International convention system in general had been analyzed to enhance the level of accuracy of the model for ICIMS. A simulation of an international conference was conducted to test the core module of the ICIMS model.

• 한국의류산업학회지
• /
• 제11권4호
• /
• pp.566-573
• /
• 2009

The purpose of this paper was to collect the information of textile and fashion trade show exhibiting such as the exhibition objectives, trade show selection criteria, reasons for not exhibiting, and exhibition performance. The data were collected from textile and fashion companies which participated in the Preview in Daegu or Seoul Fashion Sourcing Fair, or through the Research Company. The results showed that the most heavily weighted factor among reasons for not exhibiting was "high cost" and the most important exhibiting objective was "identifying the need and the preference of potential customers". "The quality and the quantity of sales lead" was ranked highly among exhibiting selection criteria. Also, the future of exhibition industry was also recognized positively and "effective PR and marketing activities" was assigned high importance among services provided by the organizer.