• Title/Summary/Keyword: organization system

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Role of Stem Cell Factor on the Recruitment of Mast Cells in the Development of Liver Fibrosis Induced by Bile Duct Ligation in the Rat (담관 결찰에 의한 간섬유증 발생에서 비만세포 동원에 미치는 Stem Cell Factor의 역할)

  • Jekal, Seung Joo;Ramm, Grant A.
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.163-172
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    • 2004
  • Mast cells (MCs) have been implicated in the pathogenesis of tissue fibrosis. However, the role of MC in the development of liver fibrosis has not been fully elucidated. Stem cell factor (SCF) is known to recruit MCs to the liver following injury as it induces mast cell proliferation, survival and differentiation from resident tissue precursors. This study examines the interaction between activated hepatic stellate cells (HSCs) and MCs in rat fibrotic liver, and SCF production by HSCs during culture in vitro. Rats were studied 4, 7, 14 and 21 days after bile duct ligation (BDL). Fibrogenesis was assessed by a measurement of collagen stained with sirius red F3B. Activated HSCs and MCs were identified by ${\alpha}$-smooth muscle actin (${\alpha}-SMA$) immunohistochemical and alcian blue staining and measured by a computerized image analysis system. SCF production was determined in rat HSC cultures using Western blotting. Mild fibrotic changes were noted in BDL rat livers as early as 4 days after induction of cholestasis. Significant expansion and organization of fibrous tissue has occurred in day 14 BDL rats which progressed to bridging fibrosis by day 21. In BDL rats, both a large number of activated HSCs and MCs were detected in portal tracts and fibrous septa. Both area of activated HSCs infiltration and density of MCs were significantly higher in all BDL group compared with Shams. In BDL rats, both areas of activated HSCs infiltration and density of MCs were no significant difference between day 4 and 7 and were significantly higher in day 14. However, the areas of activated HSCs infiltration were significantly lesser in day 21 and the densities of MCs were significantly higher in day 21 compared with day14 BDL. In BDL rats, both areas of activated HSCs infiltration and density of MCs were highly correlated with areas of fibrosis. Western blotting showed that SCF protein was consistently produced in activated HSCs by culture on plastic and freshly isolated HSCs expressed relatively little 30kD SCF compared to late primary culture activated HSCs (day 14) and passaged HSCs. These results suggest that HSCs activated in vitro produce SCF, and may play an important role in recruiting mast cells to the liver during injury and fibrosis.

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Study on the Korean Public Libraries under the period of the Japanese Rule (일제하의 공공도서관에 관한 연구)

  • Kim Po Ok
    • Journal of the Korean Society for Library and Information Science
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    • v.6
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    • pp.137-163
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    • 1979
  • The Purpose of this study is analyzed that (l) How the public Libraries under the Japanese Rule since the end of the Yi-Dynasty were recepted and generated by the people and (2) How they were organiged and managed. (3) Also it examined that how they affected the development of the libraries of today. 1. The following are the analyzed results: Three types of the public Libraries under the Japanese Rule for a period of 36 years engaged busily in colonization were Private's Public Libraries, Local Self-Government's Libraries and the Central Governmental Libraries, and were in order established. 2. They were eatablished by individuals, Confucian School Foundation, Young Men's Clubs, School Associations, Korean brethren residing abroad, or The Press Centering around the Local Self-Governments and the Japanese Government-General. 3. In 1932 of the period of the Japanese Rule, the number of Libraies gained the summit and reached 80 Libraries. The Public Libraries including the Central Governmental Libraries remained in existence until the end of the War had been kept up the functions of the Libraries, but the Private Libraries operated by the Koreans were very small and poor. As a result, most of them were closed up and some Libraries transferred their controls to the public. Until the end of the war, only a little over 10 Private Libraries were Kept up. From the aspects of it's organization system, the most of their libraries replaced their chief librarians with non-professional county-headmen or Local supporters. From the aspect of collections, they wate mainly consists of Japanese books for the proper quidance of the public thought based on the ideology of Japanese Rule to Korea and on the industrial promotion rather than books about Koreanology or Western books. At that time, the Library users were with the jobless men and students as the central figures. And the next ranking by the social position of readers was children, farmers, merchants, industrialists, public servants, miscellaneous and educators. Their reading tendencies laid stress on linguistics and literature, physical sciences and medicine, While the reading trend of military sciences and medicine, while the reading trend of military sciences and engineering were very inactive. This was because the Japanese Government-General had not kept the military collections on file. Besides, they were reluctant to make Korean's learn the professional knowledge and so the main reference materials of technology not provited. Most of the Libraries put practiced in circulation services were very important circulation in withinder of the reading room rather than in outside of the Library building. On the other hand, their circulation services has above came with many limitations. As stated above, the public Libraries' managements and activitives under the period of Japanese Rule were the way and means to achive the colonial and imperialistic purpose of the Japanese Empire.

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A Study on Developing the Classification Scheme of Library Goods (도서관용품 분류체계 개발에 관한 연구)

  • Noh, Young-Hee;Ahn, In-Ja;Park, Mi-Young;Joung, Hyun-Tae
    • Journal of the Korean Society for Library and Information Science
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    • v.45 no.1
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    • pp.125-147
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    • 2011
  • Recently, with a high demand for the construction and remodeling of libraries, and the rapid increase in the number of libraries during the last two years, the concern and need for library goods is also increasing sharply. The purpose of this study is to develop a new classification scheme of library goods by clarifying the terminology which could provide an accurate information on library goods and allow for their smooth circulation. In this study, library goods are defined as all kinds of products required for effectively collecting, organizing and providing services with library materials, and classified into library equipments and library supplies. The term, library equipment is principally used for those things that do not wear out within a certain time period, such as furniture and machinery. Library supplies refer to those things that are expendable. As the terminology is clarified, the classification scheme can be further refined. Library equipment, for example, can be classified as furniture, library system solutions, and computers and multi-media tools. Library supplies can be classified into library organization and repair supplies, sign systems, and miscellaneous articles. Finally, six major categories which include 117 different items are presented.

The Effect on the Job Performance of Open Source Software Usage in Software Development (오픈소스 소프트웨어 기반의 소프트웨어 개발 과정에서 업무 성과에 미치는 영향을 미치는 요인)

  • Kim, YoonWoo;Chae, Myungsin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.4
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    • pp.74-84
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    • 2016
  • Open Source Software (OSS) is a new paradigm for software development. The system is based on the notion of giving software (including sources) away for free, and making money on services, customizing and maintenance. For these reasons, many software companies have considered adopting and using OSS in Software R&D. A variety of factors may influence the use of decision making of OSS. The objective of this study was to explore the significant factors affecting the use decision of OSS and the job performance of OSS usage in software R&D. A research model was suggested based on the TOE Framework and Information Systems Success Model. These findings show that technical benefits of OSS have significant effects on OSS use. The technical benefits of OSS, and organization context, in turn, have significant effects on the use of OSS. On the other hand, the technical risks of OSS and the environment context have no effects on OSS use. In addition, OSS use and user satisfaction have significant effects on the individual job performance. This research contributes towards advancing the theoretical understanding of the OSS Benefits and Performance in Software Development.

Service Identification of Component-Based System for Service-Oriented Architecture (서비스 지향 아키텍처를 위한 컴포넌트기반 시스템의 서비스 식별)

  • Lee, Hyeon-Joo;Choi, Byoung-Ju;Lee, Jung-Won
    • Journal of KIISE:Software and Applications
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    • v.35 no.2
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    • pp.70-80
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    • 2008
  • Today, businesses have to respond with flexibility and speed to ever-changing customer demand and market opportunities. Service-oriented architecture (SOA) is the best methodology for minimizing the complexity and the cost of enterprise-level infrastructure and for maximizing the productivity and the flexibility of an enterprise. Most of the enterprise-level SOA delivery strategies deal with the top-down approach, which organization has to define the business processes, to model business services, and to find the required services or to develop new services. However, a lot of peoples want to maximally reuse legacy component-based systems as well as to deliver SOA into their organizations. In this paper, we propose a bottom-up approach for identifying business services with proper granularity. It can improve the reusability and maintenance of services by considering not data I/O of components of legacy applications but GUI event patterns. Our proposed method is applied to MIS with 129 GUIs and 13 components. As a result, the valiance of the coupling value of components is increased five times and three business services are distinctly exposed. It also provides a 49% improvement in reducing the relationship problems between services over a service identification method using only partitioning information of components.

Embracing Archival Arts in Contemporary Archival Practices ('아카이브 아트(archival art)'의 동시대 기록학적 함의 연구)

  • Lee, Kyong Rae
    • The Korean Journal of Archival Studies
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    • no.64
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    • pp.27-62
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    • 2020
  • The article has the characteristics of a preliminary writing about how to look at the trend of new archives 'fever' and 'impulsion' emerging around the domestic and foreign art world, which have not been paid much attention yet in the 'mainstream' archive research, and how to accept it independently. Specifically, this study aims to examine how archival art is involved in history and memory with aesthetic attitudes and methods through observation of recent tendency of domestic archive art, and what implications or influence the 'archival impulse' phenomenon in the art world can have on the research trend of 'archival studies.' First, I would like to look at the meaningful movement to reinterpret and actively accept archival impulses in concrete overseas cases, that is, the archive system of a public archive in the United States. This is followed by an attempt to explore the characteristics and characteristics of creative works that are carried out through the medium of archives, that has not yet reached the level of organization of specific archive methods but are sporadically attempted in the domestic art world. It examines how so-called 'archive artists' record unrecorded in a way that is not observed in the existing archival world, and how they summon and include excluded history in aesthetic language. In conclusion, this study explores the possibility of pulling the historical records of tradition out from archival boxes and reinterpreting them as living archives within the contemporary emotional structure from this new artistic trend called 'archival art'.

Biomimetic Analysis on the Spider Silk Apparatus for Designing the Nanofiber-spinning Nozzle (나노섬유 방사노즐 설계를 위한 거미 실크 방적장치의 생체모사 분석)

  • Moon, Myung-Jin;Kim, Hoon;Park, Jong-Gu
    • Applied Microscopy
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    • v.42 no.2
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    • pp.67-76
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    • 2012
  • The biomimetic approach on the cuticular spinning nozzles of the major ampullate silk glands in the golden-web spider Nephila calvata has been attempted using various visualizing techniques of light and electron microscopes to improve the design of spinning nozzle for producing synthetic nanofibers spun from electrospinning apparatus. The major ampullate spigot which has the most effective nozzle system to produce nanofibers for dragline silk with high strength and elasticity is connected via the bullet type spigot on anterior spinneret with flexible terminal segment. The excretory duct which transports the liquid silk feedstock from ampulla to spigot is divided into 3 limbs by loops back on itself to form an S-shape morphology that is bundled in connective tissue. Final diameter of the nanofibers at nozzle was dramatically reduced by gradual narrowing of duct cuticle less than 10 times comparing to its original size of funnel region. Moreover, the funnel has a characteristic cuticular organization with porous microstructure which seems to be related to water removal from feedstock of silk precursors. High magnification electron micrographs also reveal the presence of the spiral grooves on the surface of the cuticular intima near the valve which presumed to reduce friction during rapid flow of liquid silk.

A Study on Efficiency of Case Management Practical Model for Industrial Injury Inpatients (산업재해 입원환자를 위한 사례관리실천모형의 효과성에 관한 연구)

  • Baek, Eun-Joo
    • Korean Journal of Occupational Health Nursing
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    • v.10 no.1
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    • pp.24-40
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    • 2001
  • This study is to observe the effectiveness of the applied model and to present the improvement plan and directions for development for the case management practical model suitable for the actual condition of Korea Labor Welfare Co. and needs of the industrial injury patients. The concrete purpose of this study is: First, observe the difference of stressor experience and experience degree between the experimental group and the comparative group. Second, observe the difference of stress of the experimental group and the comparative group. Third, find out how the stress affects the support degree and satisfaction degree. Fourth, present the improvement plan of case management model, which can promote the psychosocial rehabilitation of the industrial injury patient based on the research results. The outline of the main research results identified in this study is as follows. The stressors the industrial injury patients perceived are health problems, family matters, the problems concerning hospital recuperation (hospital staff and environmental problems), economical problems, problems of coming back to society, problems with companies, problems with Korea labour Welfare Co. and other problems. And the experience of stressor was prominently lower in experimental group than comparative group in the whole problem, health problem, problems with Korea Labour-Welfare Co. and other problems. The stressor experience degree was conspicuously lower in experimental group in the whole problem experience degree, health problem experience degree, problem with Korea Labour Co. experience degree and other problem experience degree. Besides whether or not the case management is applied is having a prominent affect on the primary factor affecting the stressor experience degree, therefore the patients applied with case management has less stressor than the patient who didn't. The difference of degree of tension experienced by the stressor in both groups, the degree of stress, was not conspicuous in statistics so it shows that the application of case management in this research has not affected the degree of tension. The field which had been the most help was emotional support in help level the experimental group perceived through applying case management about industrial accident patients and recuperation, compensation problem, medical treatment problem, family matters has been helpful in this order. The help level of the whole problem was in higher level than the middle value. The stress factor which affects the case management problem settlement is the whole body of stress. The satisfaction level of help through applying case management was highest in emotional support and family matters, recuperation problem, company problem, compensation problem, and medical treatment problem was the next highest. The satisfaction level of the whole problem was higher than the middle value. The stress factor affecting the satisfaction level of help is the whole body of stress. Therefore to reduce the stress level of industrial accident patients and for them to come back to local societies, we need to reinforce the continuance and responsibility of case management model, increase staff, reinforce the role of counsel and medical treatment, intervene in the patient's plan of leaving the hospital, develop social support system and the need to establish After Care Center.

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The Impact of Family-Friendly Corporate Culture on Employees' Behavior (가족친화적 기업문화가 근로자의 행동에 미치는 영향)

  • Kim, Jeongwoo;Kim, Kyungmi;Park, Hyunjun
    • Journal of Korea Society of Industrial Information Systems
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    • v.23 no.2
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    • pp.75-92
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    • 2018
  • This study investigates the effects of family-friendly corporate policies on employees' job satisfaction, quality of life, organizational commitment, and turnover intention. Data was collected using a self-administered questionnaire from medium sized manufacturing company during the summer of 2017 and received 295 useful responses. The data was analyzed using the multiple and simple regressions. The results showed that the effects of family-friendly corporate policies were significantly positive from the employee's perspective. The employees' awareness of the family-friendly policy was positively correlated with their job satisfaction, quality of life, and organizational commitment, but it was negatively associated with turnover intention. It should be noted that the boss' support at work showed the insignificant effect on the family friendly policy awareness and this result was very different from the previous study. The study concludes that companies as well as employees benefit from family-friendly policies. The study that in order to create a family-friendly corporate culture, the company should not only introduce the policy to employees but also provide the support and atmosphere for the employees to utilize the family-friendly policy easily, and to establish a companywide support policy, organizational practitioners should find the way family-friendly policies to be rooted in the organization.

A Study on the Job Stress Factors of Dental Hygienists (울산 일부 치과위생사의 직무스트레스 요인에 대한 조사연구)

  • Kim, Ji-Hee
    • Journal of dental hygiene science
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    • v.8 no.4
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    • pp.337-345
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    • 2008
  • The purpose of this study was to investigate factors affecting dental hygienists's stress in order to provide dental hygienists's stress management methods. The results of this study were as follows. 1. A sample of 168 dental hygienists were selected to participate in this study. The participate of 66.1% was under 25 old years and 87.5% was unmarried. A majority of he dental hygienists's job place was clinical areas 86.9% and working experience was 1~4 years (47.6%). A average dental hygienists's salary was 1,000,000~1,500,000 won/month (63.7%). A average dental hygienists's working time was under 8 hours/day (57.1%). 5days/week (58.3%) was working and the participate of 78.0% was working on night-time. 2. Dental hygienists's stress under 25 years old was higher than over 26 years old (p < 0.05). It was found that dental hygienists was significantly related to stress from less income (p < 0.05), longer working time (p < 0.01). In job demand areas, Night-time workers (p < 0.05) and 5days/week (p < 0.05) worker was more stress than others participates. In job autonomy areas, longer working experience in present dental clinical(p < 0.01) and higher salary/ month (p < 0.01) were more stress. The job instability of unmarried dental hygienists were more stress than married subjects. In stress of organization system, longer working time/day (p < 0.05), under 25 years old (p < 0.01), high salary (p < 0.05), 5day/week (p < 0.05) dental hygienists's stress was higher than others.

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