• 제목/요약/키워드: optimum contents

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오만둥이(Styela plicata)에서 글리코스아미노글리칸의 최적 추출조건 설정 및 주름개선 효능 (Establishment of Optimum Extraction Conditions and Wrinkle Improvement Evaluation of Glycosaminoglycans in Styela plicata)

  • 네리 테리스 아리안;최병대
    • 한국수산과학회지
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    • 제53권5호
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    • pp.717-724
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    • 2020
  • Styela plicata are naturally-occurring marine resources easily found along the coastlines that have established their niche as functional food and nutraceuticals ingredient along with their increasing consumer demand. Ascidian contain a large amount of dietary fiber but only the meat has been utilized and consumed while the rest of its parts are discarded. Also, various studies have been conducted on the meat of ascidians while studies on the functionality of the ascidian tunics, which were mostly undervalued, were scarce. In this study, we investigated and explored the glycosaminoglycans (GAGs) contents in the tunics of S. plicata, and their potential use as functional ingredient in pharmaceutical and nutraceutical applications. Sulfated GAGs and uronic acids contents were 8.9-10.7 g/100 g and 9.4-11.3 g/100 g, respectively. Highest GAGs content was extracted with optimum Brix at 7-9. Extraction efficiency using hot water at 121℃ was 4.22% while enzyme extraction using Protamex was more efficient at 5.91%. GAGs extracted from S. plicata tunics exhibited collagenase inhibitory activity of 75.2% at 100 ㎍/mL and procollagen synthesis activity of 80.1% at 100 ㎍/mL.

Six 시그마를 이용한 연료전지 촉매구조의 최적화 (Fuel Cell Catalyst Optimization by Six Sigma)

  • 김세현;김선회
    • 한국콘텐츠학회논문지
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    • 제11권8호
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    • pp.468-474
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    • 2011
  • 연료전지에 사용되는 백금촉매 제조 공정상의 변수로서 환원제를 사용 하였다. 환원조절 횟수, 환원온도, 환원제의 양 그리고 공정시간의 네 가지의 제어인자에 변화를 주어 입자의 크기와 ICP 수율 등의 촉매 구조에 관한 최적화의 평가를 위해 six sigma 의 design of experiment 기법을 사용하여 각각의 변수간의 최적점을 확인해 보았다. 부분요인배치를 통해 입자크기 2.2nm 이하와 ICP수율 75% 이상의 촉매제조를 위하여 도출된 결과로서 주된 제어인자는 환원 시간과 환원 온도로서 밝혀졌고 각 변수의 최적 조건으로서는 환원조절횟수 1회, 환원온도 $67-88^{\circ}C$, 환원제의 양 0.5ml 그리고 10분의 공정시간에서 최적화가 이루어졌다.

저마직물의 펙티나제 정련 시 황산나트륨의 영향 (Effect of Sodium Sulfate on Ramie Fabrics Treated with Pectinase)

  • 박소영;송화순;김인영
    • 한국염색가공학회지
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    • 제22권3호
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    • pp.220-228
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    • 2010
  • This study examines the scouring effect of pectinase on ramie fabric and influence of sodium sulfate as an activator for pectinase. The scouring effects were measured by the weight loss and pectin contents. SEM, weight loss, stiffness, moisture regain and dye ability of ramie fabric teated with pectinase/sodium sulfate were also measured. When ramie fabrics were desized with $\alpha$-amylase, the optimum conditions were pH 6.5 at $60^{\circ}C$ for 80 min with 1%(o.w.f) $\alpha$-amylase concentration. When ramie fabrics were scoured with pectinase, the optimum conditions were pH 8.5 at $55^{\circ}C$ for 30 min with 10%(o.w.f) pectinase concentration. Addition of sodium sulfate improved enzyme activity significantly, which increased proportionally with increasing sodium sulfate concentration. When 50 g/l of sodium sulfate was added, the surface became cleaner compared to the enzyme treatment without salt: weight and tensile loss, moisture regain and dyeability of the treated fabrics increased, while pectin contents and stiffness decreased. Therfore, sodium sulfate was effective activator for the pectinase treatment of flax fiber.

비페닐 디메칠 디카르복실레이트 고체분산체 정제 처방의 최적화 (Formulation Optimization of the Tablet Prepared with Solid Dispersion of Biphenyl Dimethyl Dicarboxylate with Poloxamer)

  • 이장원;박은석;지상철
    • Journal of Pharmaceutical Investigation
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    • 제28권4호
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    • pp.267-274
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    • 1998
  • Biphenyl dimethyl dicarboxylate (DDB) has been used for the treatment of acute and chronic hepatitis. However, its poor solubility in water, $2.5\;{\mu}g/ml$, caused low bioavailability of the drug after its oral administration. In order to increase the dissolution of DDB in gastrointestinal tracts, consequently to increase the bioavailability of the drug, DDB tablet was prepared with solid dispersion of DDB with poloxamer 338 or 407 using a direct compression method. To improve the flowability of the solid dispersion, Aerosil was used as an adsorbent. The effect of formulation variables (poloxamer and Aerosil contents) on the dissolution rate of DDB from tablets was investigated using an analysis of variance. The dissolution rate of DDB from tablets was evaluated with KP II (paddle) method. The dissolution patterns of the drug from the tablet prepared with poloxamer 407 were affected significantly by the contents of poloxamers and Aerosil over the range employed, but those of the drug from the tablet prepared with poloxamer 338 were not. The optimum formulation of the DDB tablet, showed the same dissolution pattern as that of the reference, was obtained after polynomial equations of drug dissolution profiles for each formula were fitted to contour plots. The optimum formulation ratios of DDB:poloxamer 407:Aerosil were 1:2.5:2.5 and 1:5:5.

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Tencel FR/Cotton 복합원단의 물리적 특성 및 난연성에 관한 연구 (Study on the Physical Properties and Flame Retardancy of Tencel FR/Cotton Complex Knit Fabrics)

  • 김현아;김현철
    • 한국의류학회지
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    • 제36권7호
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    • pp.703-713
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    • 2012
  • This study analyzed the physical properties and flame retardancy of Tencel FR/Cotton complex knit fabrics in order to satisfy two aspects of eco-friendliness and functionality. The flame retardant (FR) treatment of complex knit fabrics was applied by a pad-dry-cure method for additional functionality. Tensile strength, extension, bursting strength, LOI, and flame retardancy were measured by the KS (Korean Standard) K manual. The hand value knit fabrics were measured by KES-FB system. Subsequently, tensile strength and extension of wale and tensile strength of course increased in tandem with the Tencel FR yarn content. Tencel FR/Cotton complex knit fabrics were suitable for summer-weight and for baby clothes through the KES-FB system measurements. The bursting strength of Tencel FR/Cotton complex knit fabrics decreased as the contents of the Tencel FR increased; in addition, LOI increased as the contents of Tencel FR increased. This was due to the Tencel FR flame resistance function; however, the tensile strength decreased. The optimum fiber content of Tencel FR/cotton content was 1:1. The optimum conditions of flame retardant treatment were a treatment temperature $130^{\circ}C$ and the concentration of finishing agent and assistance binder (AR4260) was 35% and 1%, respectively.

다시마 추출액을 이용한 식초 제조 (Processing of Vinegar Using the Sea Tangle (Laminaria Japonica) Extract)

  • 김경은;최옥수;이영재;김해섭;배태진
    • 생명과학회지
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    • 제11권3호
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    • pp.211-217
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    • 2001
  • Optimum processing conditions of vinegar using esa tangle extracts were investigated. Sea tangle vineagr was prepared by adding 3% and 5% of glucose, 6% and 10% of ethanol to sea tangle extracts and inoculating acetic acid bacteria. After fermentation for 30 days at 3$0^{\circ}C$, pH was similar to 3.22, 3.21, 3.25 and 3.28 days it was 4.75%, 4.77%, 5.61% and 5.87% respectively. Contents or reducing sugar was 0.70%, 0.70%, 0.88% and 0.89% in initial time of fermentation but it was rapidly decreased by 10 days of fermentation to 0.20%, 0.19%, 0.22%, and 0.21%, respectively. Ethanol contents was 5.88%, 9.77%, 5.75% and 9.68% in initial time of fermentation but it was rapidly decreased by 15 days of fermentation to 1.05%, 1.62%, 0.45% and 1.23%, respectively and it was addition of 5% glucose and 6% ethanol and fermentation for 20 days at 3$0^{\circ}C$. Quality for sea tangle vinegar manufactured using optimum condition were as follows respectively; pH 3.25, acidity 5.38%, total sugar 1.72%, iodine 1,537.2 ppm.

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재생미분말을 사용한 콘크리트 제품 개발에 대한 기초적인 연구 (The Fundamental Study on Development of Concrete-Product by Using Recycled Concrete Powder)

  • 선정수;김하석;곽은구;전명훈;김봉주;김진만
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2006년도 춘계학술논문 발표대회 제6권1호
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    • pp.19-22
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    • 2006
  • The quantity of Recycled concrete powder is increased, because it hal been ever so often crushing for production of a good quality recycled aggregates This Study is on the Development of Concrete-Product by Using Recycled Concrete Powder and alto for know performance of concrete-producted having low water contents and it is to know for all of performance of concrete-producted having low water contents The conclusions of this study are following. The use of replacement cement is not effective, because it has strengh of less than 10MPa But It is possible to develop high strength concrete-producted having 39MPa above compressive strength by using recycled concrete powder. Because strength enhancement effects by recycled concrete powder are responsible to optimum grading. The conclusions of this study are following. The use of replacement cement is not effective, because it has strengh of less than 10MPa. It is possible to develop high strength concrete-producted having 39MPa above compressive strength by using recycled concrete powder. Because strength enhancement effects by recycled concrete powder are responsible to optimum grading.

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아임계수 가수분해를 통한 돈지로부터 지방산 생산의 최적화 (Optimization of Fatty Acids Production from Lard via Subcritical Water-Mediated Hydrolysis)

  • 류재훈;신희용
    • Korean Chemical Engineering Research
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    • 제53권2호
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    • pp.199-204
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    • 2015
  • 지방산 생산을 위한 돈지의 아임계수 가수분해 공정을 최적화하기 위하여 17-run 중심합성법(central composite design)에 기초한 반응표면법(response surface methodology)이 사용되었다. 반응 온도, 오일 대비 물의 몰 비, 반응 시간과 같은 변수 및 이들의 상관관계가 지방산 함량에 미치는 영향을 조사하였으며, 지방산 함량을 예측하기 위하여 2차 다항 회귀방정식이 제안되었다. 최대 지방산 함량을 얻을 수 있는 반응 조건은 $288.5^{\circ}C$, 39.5몰 비, 29.5분이었으며, 이 조건에서의 예측 및 실제 지방산 함량은 각각 97.06% 및 96.99%였다.

알루미늄 합금의 표면경화 (Formation of Thicker Hard Alloy Layer on Surface of Aluminum Alloy by PTA Overlaying with Metal Powder)

  • Lee, Young-Ho
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 1996년도 특별강연 및 추계학술발표 개요집
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    • pp.3-15
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    • 1996
  • The formation of a thicker hard alloyed layer have been investigated on the surface of aluminum cast alloy (AC2B) by PTA overlaying process with Cr, Cu and Ni motel powders under the condition of overlaying current 125-200A. overlaying speed 150 mm/min and different powder feeding rate 5-20 g/min. In addition the characteristics of hardening and wear resistance of alloyed layer here been examined in relation to the microstructure of alloyed layer. Main results obtained were summarized as follows: 1) There was an optimum overlaying condition to get a good alloyed layer with smooth surface. This good layer became easy to be formed as increasing overlaying current and decreasing powder feeding rate under a constant overlaying speed. 2) Cu powder was the most superior one in metal powders used due to a wide optimum overlaying condition range, uniform hardness distribution of Hv250-350, good oar resistance and freedom from cracking in alloyed layer with fine hyper-eutectic structure. 3) On the contrary, irregular hardness distribution was usually obtained in Cr ar Ni alloyed layers of which hardness was increased as Cr or Ni contents and reached to maximum hardness of about Hv400-850 at about 60wt%cr or 40wt%Ni in alloyed layer. 4) Cracking occurred in Cr or Ni alloyed layers with higher hardness than Hv250-300 at mere than 20-25wt% of Cr or Ni contents in alloyed layer. Porosity was observed in all alloyed layers but decreased by usage of spherical powder with smooth surface.

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Isolation of Phytase-Producing Pseudomonas sp. and Optimization of its Phytase Production

  • Kim, Young-Hoon;Gwon, Moon-Nam;Yang, Si-Yong;Park, Tae-Kyu;Kim, Chan-Gil;Kim, Chang-Won;Song, Min-Dong
    • Journal of Microbiology and Biotechnology
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    • 제12권2호
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    • pp.279-285
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    • 2002
  • Phytase (myo-inositol hexakisphosphate phospho-hydrolase, EC 3.1.3.8) catalyzes the hydrolysis of phytate (myo-inositol hexakisphosphate) to release inorganic phosphate. A bacterial strain producing phytase was isolated from soil around a cattle shed. To identify the strain, cellular fatty acids profiles, the GC contents, a quinine-type analysis, and physiological test using an API 20NE kit were carried out. The strain was identified to be a genus of Pseudomonas sp. and named as Pseudomonas sp. YH40. The optimum culture condition for the maximum productivity of phytase by Pseudomonas sp. YH40 were attained in a culture medium composed of $1.0\%$ (w/v) glycerol, $2.0\%$ (w/v) peptone, and $0.2\%$ (w/v) $FeSO_4{\cdot}7H_2O$. Within the optimal medium condition, the production of phytase became highest after 10 h of incubation, and the maximal phytase production by Pseudomonas sp. YH40 was observed at $37^{\circ}C$ and pH 6.0.