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A Clinical Analysis of Surgically Managed Thyroid Nodule (외과적으로 치료한 갑상선 결절에 대한 임상적 고찰)

  • Jung In-Kyu;Kim Lee-Su;Choi Won-Jin
    • Korean Journal of Head & Neck Oncology
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    • v.9 no.1
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    • pp.16-24
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    • 1993
  • During 7 years, from Jan. 1986 to Dec. 1992, authors studied 208 cases of the surgically managed thyroid nodules at the Department of General Surgery, Han Kang Sacred Heart Hospital and obtained the following results. 1) Among the total 208 cases, male to female ratio was 1:11.2 in benign thyroid diseases and 1:9 in malignant thyroid diseases. The benign disease was prevalent between second and forth decade comparing with malignant disease between third and fifth decade. 2) The most common duration of illness was 3 months(26.0%). 3) Palpable neck mass was the most common chief complaint(100%). Palpitation. fatigue, and sweating were common complaints in patient with benign disease, and fatigue, palpitation, and sweating in malignant disease in decreasing order of frequency. 4) 55.8 % of lesions were in right lobe, 33.2% in left lobe, 5.8% in diffuse type, 4.8% in bilateral lobes, and 0.5% in isthmus. 5) The most common size of nodule was between 2.0cm and 3.9cm in diameter, which consisted of 55.1% of benign disease and 48.0% of malignant disease. 6) 86.5% of thyroid function test showed euthyroidism, 10.1% hyperthyroidism, and 3.4% hypothyroidism. 7) Thyroid scanning of 176 patients revealed cold nodules in 92.5% of benign diseases and in 92.9% of malignant diseases. 8) The most common benign disease was adenomatous hyperplasia(62.7%), and the most common malignant disease was papillary adenocarcinoma(80.0%). 9) Fine needle aspiration cytology was performed in 91 cases, and it showed 69.0% of sensitivity, 90.3% of specificity, and 83.5% of accuracy. 10) Frozen biopsy was performed in 109 cases. and it showed 93.9% of sensitivity, 100.0% of specificity, and 98.2% of accuracy. 11) The most commonly performed operation was unilateral lobectomy(including unilateral lobectomy with isthmectomy)(79.1%) in benign disease. and total thyroidectomy(62.0%) in malignant disease. 12) Postoperative complication showed 5 cases of wound infection (2.4%), 3 cases of transient hypoparathyroidism(1.4%), 3 cases of transient hoarseness(1.4%), 2 cases of postoperative bleeding(1.0%), 1 case of permanent hypoparathyroidism(0.5%), 1 case of permanent hoarseness(0.5%), and 1 case of postoperative pneumonia (0.5%).

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Preparation and Characterization of Organic Solvent-resistant Polybenzimidazole Membranes (용매저항성 폴리벤즈이미다졸 분리막의 제조 및 특성평가)

  • Jeong, Moon Ki;Nam, Sang Yong
    • Applied Chemistry for Engineering
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    • v.28 no.4
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    • pp.420-426
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    • 2017
  • Recently, solvent-resistant nanofiltration membranes have been studied for the separation of solvents or solutes using a molecular weight cut-off system of the polymer which is resistant to a specific solvent. Required conditions for these membranes must have are excellent physical properties and solvent resistance. Polybenzimidazole, which is known to be one of the most heat-resistant commercially available polymers, has an excellent inherent solvent resistance and it is even insoluble in stronger organic solvents when cross-linked. Therefore, in this study, the applicability of polybenzimidazole as a solvent resistant nanofiltration membrane was discussed. The membrane was fabricated using the non-solvent induced phase separation method and showed a suitable morphology as a nanofiltration membrane confirmed by field emission scanning electron microscopy. In addition, the permeance of the solvent in the presence or absence of cross-linking was investigated and the stability was also confirmed through long operation. The permeance test was carried out with five different solvents: water, ethanol, benzene, N, N-dimethylacetamide (DMAc) and n-methyl-2-pyrrolidone (NMP); each of the initial flux was $6500L/m^2h$ (water, 2 bar), $720L/m^2h$ (DMAc, 5 bar), $185L/m^2h$ (benzene, 5 bar), $132L/m^2h$ (NMP, 5 bar), $65L/m^2h$ (ethanol, 5 bar) and the pressure between 2 and 5 bar was applied depending on the type of membrane.

Modification of the Existing Binders for Highly-Shattering, Short-Stem Rice Varieties (I) (탈립성(脱粒性), 단간종(短稈種)인 통일계품종(統一系品種)에 적합(適合)한 바인더의 개량(改良) 개발(開發)에 관(關)한 연구(硏究)(I))

  • Choi, Hee Seung;Chung, Chang Joo
    • Journal of Biosystems Engineering
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    • v.7 no.1
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    • pp.17-32
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    • 1982
  • The binders introduced in Korea were originally designed to be used for Japonica-type varieties which have relatively long stem and are highly resistant to shattering. In order to use it for Tongil varieties which are short and easy to be shattered, mechanical modifications are necessary to reduce a grain loss incurred during binder operation. This study was intended to investigate analytically and experimentally the major sources of grain losses caused by three kinds of binders now introduced in Korea. Actual modification for each of three binders was done and experimentally compared to see if any improvement on grain loss was achieved. The results obtained in this study are summarized as follows; 1. It was required that the power transmission of binder should have a shifting mechanism so that velocities of pick-up and traveling units could be changed independently as desired according to the Japonica-type and Tongil varieties. In other words, the desired velocity of traveling unit should be obtained by shifting the transmission and the velocity of pick-up unit should be selected by reaping clutch according to the variety independent of the velocity of traveling unit as shown in Fig. 6. 2. To reduce grain loss it was desired that the moving parts of the pick-up unit should have the lowest possible velocities in harvesting Tongil varieties, unless the reduction of the speed be hindered the conveyance of the material. Based on the study, it was concluded that the velocities of pick-up unit be reduced by about 35% of those of the existing units. 3. It was found that the lug at the upper rotating section of pick-up case gave a severe impact on the ears of rice to increase grain loss. The optimum design of pick-up case to protect the ears from the protruding part of the lug was recommended by the result of analysis of the trajectory of the end-point of lug at the position. 4. It was proved analytically and experimentally that pick-up unit at the lower-rotating part was the other important source of grain loss in pick-up and divider assembly. In order to reduce a grain loss incurred by lugs at their lower-rotating section, it was suggested to improve it by (1) widening the space between right and left lower-rotating section, (2) shortening the length of lugs, (3) enlargement of the angle between the pick-up case and ground-level, and (4) attaching guard to right and left dividers so that the rotating lug could not give a high impact to the paddy hill. 5. Pick-up and divider assembly of the original binder of three models studied was modified according to the suggestions that were given by the preliminary study. Field test showed that the modified binders were able to reduce grain losses by about 0.4-0.7 percentage points compared to those without modification.

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Effect of Bundle icing Forces on the Shattering Loss of Grains (바인다의 효출력이 곡물탈립손실에 미치는 영향)

  • 백풍기;정창주
    • Journal of Biosystems Engineering
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    • v.3 no.1
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    • pp.20-36
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    • 1978
  • The effect of binder kicking forces on the shattering losses of paddy rice, which has been widely understood as an outstanding loss factor in harvesting with a binder, were experimentally assessed in this thesis.Through the field tests the optimum time of harvest, in terms of grain moisture contents, was found by considering harvesting losses for two rice varieties, harvested by two different binders, at four or five grain moisture levels.A device was designed and manufactured to apply various kicking forces to the bundles and was used in the bundle kicking tests. It was intended to find out the optimum range of kicking force to minimize the kicking losses. Based on the study, modification of the existing binder kicking mechanism was suggested. The following is a summary of the results of this thesis. 1. In Suweon 258 variety, as the grain moisture content is reduced, so the cutting loss and the kicking loss increase. The grain losses range from 0.77 to 0.82 percent of total field yield for the cutting loss, from 1.83 to 2.01 percent for the kicking loss, and from 2.60 to 2.83 percent for the field loss, when the moisture content is about 22 percent. 2. In Jinheung variety , the field losses increased as the grain moisture content decreased . When the moisture content was 20 percent, the field loss, cutting loss and kicking loss was 0.42-0.49 % , 0.30-0.35, and 0.12 -0.14% of the total field yield, respectively. 3. The difference in the field loss , cutting loss, and kicking loss for the two binders was 0.23% , 0.05% and 0.18% respectively in Suweon 258 variety, and 0.07% , 0.02% and 0.05% respectively ini Jinheung variety. The grain losses for binder B were slightly higher than those for binder A. 4. In the statistical analysis of each variety , the kicking force and the moisture content of the grain, and its interaction were all highly significant at 1% level by T test .The optimum kicking force was found to be in the 3.0-0.4kg range. This does not interrupt the binder operation, while ioses are kept to an acceptale level. 5. To reduce the kicking force of the eXlstmg binder mechanism, the speed of rotation of the kicking arm needs to be redued by increasing the number of driving sprocket teeth, and the position and gear ratio of the knotter-bill and driving bevelgear have to be change to give a !motter-bill speed of 1110 rpm. It is also desirable to attach a belt conveyor which smoothly carries the bundle to the ground. 6. The optimum harvesting time cased on maximum field yield was found to be at a grain moisture content of around 22 percent for Suweon 258 variety, and 20 percent for Jinheung variety. Tota] field yield and field yield at the time amounted to 9, 812.5 kg/ha, 9, 302. 5kg/ha respectively for the Suweon 258, and 7, 819.5 kg/ ha, 7, 158.7 kg/ha respectively for the Jinheung variety.

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Magnetic Resonance Imaging Assessment of Acromion Morphology and Superior Displacement of the Humeral Head in the Impingement Syndrome (충돌 증후군에서 견봉 형태 및 상완골 두 상방 전위의 자기공명영상 분석)

  • Koo Bon Seop;Kim Kyung Chul;Oh Jung Hee
    • Clinics in Shoulder and Elbow
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    • v.2 no.1
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    • pp.28-34
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    • 1999
  • Purpose: We studied magnetic resonance imaging of acromion morphology and superior displacement of the humeral head in the patients with diagnosis of rotator cuff impingement syndrome, and also documented the relationship of type Ⅲ acromion to the rotator cuff tear. Materials and Methods: We reviewed retrospectively 40 patients(40 shoulders) who had arthroscopic treatment for the diagnosis of stage II impingement or rotator cuff partial tear and did not have other risk lesions except acromion factor. The mean age was 48.7 years at operation. 21 men(2l shoulders), mean age of 26 years, were used as controls. Acromial type, tilt, and superior displacement of humeral head in sagittal plane, and acromial lateral angulation in coronal plane were measured. Four parameters of the patients were compared with those of control group. And then, the data were subdivided and analyzed with respect to acromial type and patient age in the impingement group. Student t test and multi-way ANOVA were used. Results: In impingement group, Farley's type I acromion, 33%, type Ⅱ, 38%, type Ⅲ, 27% and type Ⅳ, 2%. Superior displacement of humeral head( 4.8mm) were characteristic in the impingement group compared with the control group(1.3mm)(p<0.05). But acromial tilt and lateral angulation were not statistically different. In the analysis of the impingement group, the change of 4 parameters was not significant with respect to age(p>0.05), but lateral angulation in type I acromion(18 degree) and superior displacement of humeral head in type Ⅲ acromion(6.3mm) were significantly increased(p<0.05). All 4 parameters were not different between two subdivided types of type Ⅲ acromion. Conclusion: All types of acromian and large lateral angulatian cauld develop impingement syndrame, but acromial tilt was nat risk factar. Appearance of type Ⅲ acromian and increased superiar displacement of humeral head were characteristic findings in the impingement syndrame. Superiar displacement of humeral head as a result of degenerative change of rotatar cuff was probably primary cause far impingement. The type Ⅲ acromian might be an acquired farm, which cauld be expected to accelerate the tear of rotatar cuff as a cansequence.

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Low Noise Vacuum Cleaner Design (저소음 청소기 개발)

  • Joo, Jae-Man;Lee, Jun-Hwa;Hong, Seun-Gee;Oh, Jang-Keun;Song, Hwa-Gyu
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.11a
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    • pp.939-942
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    • 2007
  • Vacuum cleaner is a close life product that can remove various dusts from our surroundings. However well vacuum cleaner clean our environments, many people are looking away from it, due to its loud noise. Its noise causes a big trouble in the usual life, for example, catch calls, TV watching and discussing etc. To reduce these inconveniences, noise reduction methods and systematic design of low noise vacuum cleaner are studied in this paper. At first, sound quality investigation is performed to get the noise level and quality that make people TV watching and catch calls available. Based on the European and domestic customer SQ survey result, sound power, peak noise level and target sound spectrum guideline are studied and introduced. As a second, precise product sound spectrums are designed into each part based on the sound quality result. Fan-motor, brush, mainbody, cyclone spectrums are decided to get the final target sound based on the contribution level. Fan-motor is the major noise source of vacuum cleaner. Specially, its peak sound, RPM peak and BPF Peak, cause the people nervous. To reduce these peak sounds, high rotating impeller and diffuser are focused due to its interaction. A lot of experimental and numerical tests, operation points are investigated and optimization of flow path area between diffusers is performed. As a bagless device, cyclones are one of the major noise sources of vacuum cleaner. To reduce its noise, previous research is used and adopted well. Brush is the most difficult part to reduce noise. Its noise sources are all comes from aero-acoustic phenomena. Numerical analysis helps the understanding of flow structure and pattern, and a lot of experimental test are performed to reduce the noise. Gaps between the carpet and brush are optimized and flow paths are re-designed to lower the noise. Reduction is performed with keeping the cleaning efficiency and handling power together and much reduction of noise is acquired. With all above parts, main-body design is studied. To do a systematic design, configuration design developments technique is introduced from airplane design and evolved with each component design. As a first configuration, fan-motor installation position is investigated and 10 configuration ideas are developed and tested. As a second step, reduced size and compressed configuration candidates are tested and evaluated by a lot of major factor. Noise, power, mass production availability, size, flow path are evaluated together. If noise reduction configuration results in other performance degrade, the noise reduction configuration is ineffective. As a third configuration, cyclones are introduced and the size is reduced one more time and fourth, fifth, sixth, seventh configuration are evolved with size and design image with noise and other performance indexes. Finally we can get a overall much noise level reduction configuration. All above investigations are adopted into vacuum cleaner design and final customer satisfaction tests in Europe are performed. 1st grade sound quality and lowest noise level of bagless vacuum cleaner are achieved.

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The effects of Hyangbujapalmultang on Learning and Memory of AD Rats using Morris water maze paradigm (향부자팔물탕(香附子八物湯)이 Alzheimer's disease 모델 백서(白鼠)의 학습과 기억에 미치는 영향(影響))

  • Kang Hyun-Geun;Kim Jong-Woo;Whang Wei-Wan
    • Journal of Oriental Neuropsychiatry
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    • v.10 no.1
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    • pp.39-51
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    • 1999
  • The effects of Hyangbujapalmultang on the enhancement of learning and memory of AD model rats were studied with Morris water maze. Sample group was electrolytically lesioned on nucleus basalis of Meynert(nbM), and then daily treated with the medicine for two months. Control group with nbM lesion, and sham group with the sham operation were treated the vehicle for the same duration. The following results were observed. 1. As the learning trials of Morris water maze were proceeded, sham group showed the escape latency from $54.7{\pm}2.28$ seconds in 1st trial to $13.3{\pm}3.27$ seconds in 7th. The control group showed the escape latency from $58.0{\pm}1.78$ seconds in 1st trial to $51.3{\pm}3.52$ seconds in 7th. The sample group showed the escape latency from $57.0{\pm}2.21$ seconds in 1st trial to $28.4{\pm}4.82$ seconds in 7th. Therefore, these data shows that all three groups were improved in learning capacity as trials were proceeded, but the sample group showed more prominent improvement in learning compared with the control group(p<0.05). 2. In memory retention test of Morris water maze that counts the staying time in the target area during 30 seconds of freely swimming period, sham group stayed for $4.81{\pm}1.15$ seconds, the control group stayed for $1.27\pm}0.78$ seconds, and the sample group stayed for $4.17{\pm}1.47$ seconds. The analysis of the memory retention data shows that the sample group marked more improvement in memory retention compared with the control group, but could not obtained statistically significant result(p<0.05). With the experimental results above, Hyangbujapalmultang can be supposed to have the improving effects on the learning of AD model rats induced by electrolytic lesion of nbM.

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A Study on Evaluating Length Limit in Tangent Section of Highway Based on Driver's Workload (운전자 작업부하를 고려한 최장 허용 직선길이 결정에 관한 연구)

  • 정봉조;강정규;김주영;장명순
    • Journal of Korean Society of Transportation
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    • v.20 no.2
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    • pp.17-26
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    • 2002
  • Driver's psychophysiological load is one of the key measures for evaluating the safety of the highway. The purpose of this study is to propose and to test the methodology of evaluating the length limit of tangent section using driver's psychophysiological load. Driver's psychophysiological data is represented by the data acquire by frontal and occipital lobe. In order to compare the differences between tangent segments and the orders, real road driving experiments were performed. We collected psychophysiological data during the operation of vehicles. The experimental data were analyzed using FFT (Fast Fourier Transform) and relative power spectrum tools. These routine produces the beta value which is a major factor in consideration of driver's condition. The results in this study are summarized as follows: (1) A new methodology of evaluating the length limit in tangent section of highway using driver's psychophysiological load was proposed. (2) It was observed that driver's work load at tangent section was three times lower than that at the other section types. The beta value at tangent section is 2.219, while that at general section is 0.821. (3) It was observed that the driver's work load was significantly dropped to 0.428 after the continuous driving of 4.2km tangent section. (4) Based on the experimental subjects(from 27 Years to 31). we suggest that 30 times of design speed(3.0 km) could be acceptable as the length limit of tangent section in highway rather than the Previous limit which is 20 times of design speed(2.0km).

Demand Surveys for Big Research Facilities and Equipments to Advance National S&T Research Infrastructure (과학기술 하부구조 선진화를 위한 대형 연구장비의 수요 조사)

  • 권용수;민철구
    • Proceedings of the Technology Innovation Conference
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    • 1997.12a
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    • pp.159-176
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    • 1997
  • This paper deals with demand surveys for big science and technology research facilities and equipments to advance national S'||'&'||'T research infrastructure. We perform surveys thrice based on applied Delphi method on the future demand of big S'||'&'||'T research facilities and equipments among Korean scientists and engineers. We employ the concept of big S'||'&'||'T research facilities and equipments as follows: \circled1 The operating size of it is equivalent to that of an institute or research center, and/or \circled2 The users in various disciplines are many, and/or \circled3 The application areas or spill-over effects are large, and/or \circled4 The scale and scope of research objects is equivalent to that of mega science area such as earth.oceanography.space, and/or \circled5 The expenses for installing and operating it are to be supported by government, and/or \circled5 The facilities are expected as necessary for international joint research, and/or \circled7 It is necessary for promoting creative basic science and developing creative technology. We ask the respondents to answer the following questionnaire: - How to prioritize the equipments according to the degree of importance\ulcorner $\square$ Promotion of basic science and mega science, the development of the technologies to enhance the public welfare, the competitiveness of industrial technologies, the job creation for the S'||'&'||'T personnel, and international cooperation. - Who should be in charge of acquisition and operation of the equipments\ulcorner $\square$ Industry, Government Research Institutes, Academy, ERC and SRC. - When shall we acquire the equipment\ulcorner $\square$ Within 2000, 2002, 2007, 2012, and 2017. - How shall we acquire the equipments\ulcorner $\square$ International Joint Development, Domestic Development, Acquisition from Overseas, - How much will the equipment generate spill-over effects to national competitiveness\ulcorner $\square$ Promotion of basic science, contribution to the economy, supply of S'||'&'||'T personnel, and international cooperation. We suggest the following equipments as prioritized candidates after consulting the officers from MOST, MOE, MIC, MOEN and experts from KBSI and STEPI:(table omitted) where, #1, Korea Advanced Liquid Metal Reactor, #2. 800 MHz Superconduction Fourier-Transform Nuclear Magnetic Resonance Spectrometer, #3. Ion Accelerator, #4. Seismic Test Facility, #5. Transonic Wind Tunnel, #6. Radio Telescope for Very Long Baseline Interferometer, #7. 3000t Universal(or Large Structure) Testing Machine, #8. Compost Facility or Plasma Pyrolysis Facility.

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Congenital cystic adenomatoid malformation (선천성 낭포성 선종양기형 -1례 보고-)

  • Sun, Kyung;Baek, Kwang-Je;Lee, Chol-Sei;Chae, Sung-Soo;Kim, Hark-Jei;Kim, Hyung-Mook
    • Journal of Chest Surgery
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    • v.17 no.1
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    • pp.118-124
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    • 1984
  • Congenital Cystic Adenomatiod Malformation (C.C.A.M.) is rare, but one of the most common congenital pulmonary anomalies that cause acute respiratory distress in the newborn infants. It is characterized and differentiated from the diffuse pulmonary cystic disease pathologically, i.e. adenomatoid appearance due to marked proliferation of the terminal respiratory components. An 2/12 year old male patient was suffered from respiratory distress and cyanosis on crying since birth, but no specific therapy was given. With progression of symptoms, he came to Korea University Hospital for further evaluation and then transfered to Dept. of Chest Surgery for operative correction under the impression of Congenital Obstructive Emphysema suggested by a pediatrician. On gestational and family history, there was nothing to be concerned such as congenital anomaly. Physical examinations showed; moderate nourishment and development (Wt. 5.5kg), cyanosis on crying, both intercostal and lower sternal retraction on inspiration, Lt. chest building with tympany, Rt. shifting of cardiac dullness, decreased breathing sound with expiratory wheezing on entire Lt. lung field, decreased breathing sound on Rt. upper lung filed, and tachycardia. The remainders were nonspecific. Laboratory findings were normal except WBC $14000/mm^3$ (lymphocyte 70%), Hgb 9.8m%, Hct 28%, negative Mantaux test, and sinus tachycardia and counter-clockwise rotation on EKG. Preoperative simple Chest PA revealed marked hyperlucent entire Lt. lung, herniation of Lt. upper lobe to Rt., collapsed Rt. upper lobe, tracheal deviation and mediastinal shifting to Rt., and no pleural reaction. At operation, after Lt. posterolateral thoracotomy, 4th rib was resected. Operative findings were severe emphysematous changes limited to both lingular segmentectomy was done. The resected specimen showed slight solidity, measuring $8{\times}4.5{\times}2cm$ in size, and small multiple cystic spaces filled with air. Microscopically, entire tissue structures were glandular in appearance, cyst were lined by ciliated columnar epithelium, and occasional cartilages were noted around the cystic spaces. Bronchial elements were dilated but normal pattern on histologically. The patient had a good postoperative courses clinically and radiologically, and discharged on POD 10th without event. The authors report a case of Cogenital Cystic Adenomatoid Malformation (C.C.A.M.)

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