• Biomedical Science Letters
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• v.23 no.2
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• pp.133-137
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• 2017

Periodontitis is the major causation of tooth loss in the elderly population. Multiple risk factors include oral microorganisms, smoking, metabolic syndrome, and genetic factors influence periodontitis development. In this study, we conducted a replication study of using previous Korean GWAS results by examining an independent population. The study population was recruited from Mir Dental Clinic, Daegu, Korea. In total, 93 samples were evaluated from July 2016 to January 2017. The sample groups include relatively older patients (>60 years) with no periodontitis (n = 31) and relatively younger patients (range 40~60 years) with severe periodontitis (n = 62). A total of seven markers which were previously reported to be associated with periodontitis were genotyped. Among the seven SNPs, rs16846206 and rs2392510 showed a significant association by logistic regression analysis and Chi square test, respectively. The former SNP showed significant association with severe periodontitis, whereas this study also showed same tendency in which individuals with the minor allele are significantly more frequent in cases than those in controls. The SNP is located on a coding gene (SLC9C2), where the alanine residue 505 is replaced by glycine (Ala505Gly). The later SNP was significant when differed between case and control groups, but there was no significance by logistic regression analysis when controlled for age and sex as covariant. Although the study population size examined in the current study was relatively smaller compared to previous studies, our results implicated that at least the two SNPs (rs16846206 and rs2392510) might be important candidates for the further genetic study.

• Tuberculosis and Respiratory Diseases
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• v.61 no.3
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• pp.279-284
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• 2006

A multiple primary malignant tumor is a disease mainly encountered in the of the older age groups. Attempts should be made to rule out a second primary malignant neoplasm in the elderly patients with unusual signs and symptoms. We encountered a case of a 67-year-old male with triple primary malignant tumors of the stomach, larynx, and lung. The patient had been treated with a subtotal gastrectomy for early gastric cancer in 1991 and a Laser laryngectomy for the laryngeal squamous cell carcinoma in 2003. In 2005, lung cancer was found with the biopsy revealing an adenosquamous carcinoma. Systemic chemotherapy was performed.

• Journal of Korean Public Health Nursing
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• v.26 no.3
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• pp.478-490
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• 2012

Purpose: The purpose of this study was to investigate the effects of oral exercise on oral function and quality of life among community-dwelling elders. Methods: This was a quasi-experimental study. Sixty four participants were recruited from the dental clinic of a public health center in G City, Gyeonggi-do. Thirty one participants were assigned to the experimental group and 33 to the control group. Participants in the experimental group performed oral exercise once a week for a period of three months. Subjects in the The control group received usual oral education. The Scores for oral function and quality of life were measured before and after the treatment. Data were analyzed using SPSS WIN 14.0. Results: After the experiment, statistically significant differences were observed between the two groups. were observed. The amount of saliva (p<.001), and the scores of for oral function (p<.001), and quality of life (p<.001) were higher in the intervention group compared to the control group. Conclusions: Oral exercise programs were effective in improving the oral function and quality of life among community-dwelling elders. Oral exercise could be an effective oral health nursing intervention for older people in the community.

• Journal of Families and Better Life
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• v.15 no.2
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• pp.155-172
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• 1997

The purpose of this study is to examine the relation between the later personality adjustment types and the elderly percepted conflict with their married children. The subjects for this study are the aged over 60 years in Seoul both having the eldest sons' couples and perceiving their own economics level as the middle-upper. The results based on this are as followed: 1) The Active Integrated Coper is appeared in the higher educational level group in the better health condition in the 11-30 thousand won of personal expense in the professional and management occupation and in the more vigorous for social activity. The Failing Overcoper the Dependent Passive Coper and the Self-negating Undercoper is appeared in th female elder group in the later group of the older age in the lower educational level in the worse health condition in the group without spouse in one without income in the below 10 thousand won in the less preparation for the later life. 2) The problems of emotion and iew of values bring about the conflicts between them and theirs rather than the financial problem. when they are in the worse health condition in the group without religion in the group not cohabiting their eldest sons' couples and in the group not well-prepared for their later life as the socio-demographic variables the old recognized the seriousness of the conflict with their eldest sons' couples. 3) The lower the Active Integrated Coper is and the higher the Failing Overcoper is the more intense the conflict between them and their eldest sons' couples is. 4) The t-test to examine the difference in the old's conflict with their eldest sons' couples among the later groups shows that it is in the less the Active Integrated Coper and in the more the Failing Overcoper that the conflict is more surfaced. 5) The educational level the level of the later life preparation the contact frequency with their daughter the level of their social activity as the socio-demographic variables and the Failing Overcoper as the later personality adjustment type answer for 22 percentage of the conflict.

• Korean Journal of Community Nutrition
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• v.10 no.5
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• pp.645-653
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• 2005

The prevalence of undernutrition in hospital populations is known to be high. The presence of malnutrition is associated with depression, infections, sarcopaenia, falls, fractures, reduced autonomy and increased mortality. This study specifically examined the prevalence of malnutrition in patients aged 65 or older at the time of admission as determined by the Mini Nutritional Assessment (MNA) which has been a frequently used nutritional risk screening tools in detecting undernutrition in old people. This study was done for one hundred eight hospitalized geriatric patients in Seoul National University Bundang Hospital, Seoul, Korea. On admission baseline history, anthropometrics measurements, laboratory data and nutritional status by MNA were assessed. Length of hospital stay was obtained by reviewing medical charts. We used one-way analysis of variance to compare the differences in variables. Spearman's rank correlation coefficients were calculated for associations between MNA and variables. On admission, $22.3\%$ of patients were malnourished and $40.7\%$ were at risk of malnutrition according to the MNA. Percent of ideal body weight, anthropometrics data, albumin, and hemoglobin were lower in the malnourished patients (p<0.05). The malnourished patients stayed in the hospital 7.3 days longer, as compared with well nourished patients (p<0.05). Percent of ideal body weight, albumin, hemoglobin and total cholesterol were correlated inversely with nutritional status according to MNA (p<0.05). MNA can be used for nutritional assessment in Korean old people, because MNA significantly correlated with other nutritional assessment parameters, such as, anthropometric and laboratory data in hospitalized geriatric patients. The high prevalence of malnutrition in the elderly was observed and the presence of malnutrition on admission predicted a significant increase in the length of hospital stay in this study. Therefore further studies are needed to determine whether nutritional interventions in old people with low MNA scores can improve clinical outcomes during the hospital course.

• Journal of Korean society of Dental Hygiene
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• v.20 no.1
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• pp.41-51
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• 2020

Objectives: The purpose of this study was to investigate the effects of oral health behaviors of patients with hypertension and diabetic patients on the number of remaining teeth in Korean adults over 45 years of age, furthermore, we also aimed to develop oral health care programs and health promotion for patients with hypertension and diabetes. Methods: Altogether, 1,526 subjects with hypertension and diabetes from the 6th Korean National Health and Nutrition Survey (2013-2015) were analyzed. Results: A multiple logistic regression analysis was performed to determine the effects of oral health behavior and periodontal disease on residual teeth in patients with hypertension and diabetes after adjusting for age. We found 1.53 times the risk of having less than 20 remaining teeth in the group of brushing more than 3 times a day (95% CI: 1.00,2.35, p<0.001), 2.27 times (95% CI: 1.23-4.17, p<0.05) in the group not using the dental floss group 0.05), compared to the group undergoing regular dental check-up (95% CI: 0.93-1.85, p>0.05), compared to the non-smoking group 0.77 times (95% CI: 0.51-1.14, p>0.05), 1.33 times (95% CI: 0.98-1.80, p>0.05) in the drinking group compared to the non-drinking group, in the periodontal disease group, the risk of having less than 20 remaining teeth was 2.19 times higher (95% CI: 1.48-3.24, p>0.001) than in the normal group. Conclusions: As a super-aging society, develops in Korea, the prevalence of hypertension and diabetes will increase gradually. Therefore, an oral health policy should be implemented at the national level for the prevention and treatment of periodontal disease as well as the management of oral health the elderly.

• The Journal of Internal Korean Medicine
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• v.24 no.4_2
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• pp.1037-1045
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• 2003

Objectives: Dementia is a kind of chronic, progressive, degenerative disease. The symptoms results in troubles in intellectual functions. memory, orientation, intelligence, judgement, common sense and calculating ability. The Korean version of Mini-Mental State Examination(MMSE-K) has been used widely to screen cognitive impairment of the elderly in Korea. This instrument has been specifically developed and evaluated for the assessment of cognitive function in older Korean populations. Methods: Cognitive function was evaluated by the Korean version of Mini-Mental State Examination(MMSE-K). This patient was diagnosed as Vascular dementia and We treated her cognitive impairment with Gagambosim-tang(Jiajianbuxin-tang). Results: After treated with Gagambosim-tang(Jiajianbuxin-tang), Cognitive function was improved. Conclusion: This report may have a meaning to treat Vascular dementia.

• Journal of Chest Surgery
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• v.32 no.11
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• pp.1017-1022
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• 1999

Background: An increasing number of elderly are referred for open heart surgeries(OHS). These patients are assumed to have significantly increased morbidity and mortality because of compromised functional reserves in their vital organs. We reviewed the results of OHS patients who were 70 years old or older. Material and Method: Thirty six consecutive septuagenarians underwent OHS from 1995 to 1997. Operations were coronary artery bypass grafting(CABG) in 26 including 3 left main surgical angioplasty, valve replacement in 7, MVR+CABG in 2, and ASD closure+TAP in 1. Statistical tests were carried out to compare survivor group with nonsurvivor group in respect to risk factors including NYHA functional class, LVEF, emergent operation, IABP support, CPB/ACC time, ventilator time cardiac index, ICU stay and hospital stay for operative mortality. Result: Operative mortality rate and postoperative complication were 16%(6/36) and 50%(18/36). One-year and 3-year actuarial survival rates were 76%. Nine patients(25%) had major complications including third-degree A-V block(2), respiratory failure(1), stroke(3), renal failure requiring dialysis(3) and postoperative hemorrhage(2). The causes of death were pneumonia(1), bleeding(1), acute renal failure(1), low cardiac output(1), third-degree A-V block(1), and ventricular tachycardia(1). The univariate analysis of mortality shows that NYHA class IV, LVEF<40%, lesser values for C.I, and longer time for ventilatory support were associated with the risk factors(p value=0.03, 0.001, 0.007, and 0.014). The emergent operation, CPB/ACC time, IABP support, ICU stay and hospital stay were not significant. Conclusion: We conclude that cardiac operation can be performed in septuagenarians with acceptable outcomes when done in patients with normal to moderately depressed left ventricular function and adequate functional reserves in their vital organs.

• Journal of Korean Neurosurgical Society
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• v.58 no.3
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• pp.262-270
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• 2015

Objective : Long-term oral anticoagulation or antiplatelet therapy has been used with increasing frequency in the elderly. These patients are at increased risk of morbidity and mortality from expansion of intracranial hemorrhage. We conducted a single-center retrospective case control study to evaluate risk factors associated with outcomes and to identify the differences in outcome in traumatic brain injury between preinjury anticoagulation use and without anticoagulation. Methods : A retrospective study of patients who underwent craniotomy or craniectomy for acute traumatic cerebral hemorrhage, between January 2005 and December 2014 was performed. Results : A consecutive series of 50 patients were evaluated. The factors significantly differed between the two groups were initial Prothrombin Time-International Normalized Ratio, initial platelet count, initial Glasgow Coma Scale score, and postoperative intracranial bleeding. Mean Glasgow Outcome Scale (GOS) score were similar between the two groups. In the patient with low-energy trauma only, no significant differences in GOS score, postoperative bleeding and many other factors were observed. The contributing factors to postoperative bleeding was preinjury anticoagulation and its adjusted odds ratio was 12 [adjusted odds ratio (OR), 12.242; p=0.0070]. The contributing factors to low GOS scores, which mean unfavorable neurological outcomes, were age (adjusted OR, 1.073; p=0.039) and Rotterdam scale score for CT scans (adjusted OR, 3.123; p=0.0020). Conclusion : Preinjury anticoagulation therapy contributed significantly to the occurrence of postoperative bleeding. However, preinjury anticoagulation therapy in the patients with low-energy trauma did not contribute to the poor clinical outcomes or total hospital stay. Careful attention should be given to older patients and severity of hemorrhage on initial brain CT.

• Journal of the Korean Society of Safety
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• v.27 no.4
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• pp.101-107
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• 2012

The statistics of industrial accident reported by ministry of Employment and Labor denoted a significant increase of musculoskeletal disorders(MSDs) after 1993, and showed the higher incident rate by 71.3% over the overall worker's disorders. Also, it was expected that Korean society will become the post-aged society in 2026 with 20.8% of elderly who is over 65 years old. The reports suggest possible problems caused by the older worker known to have reduced working ability than the young counterparts. On this basis, the goal of this study was to investigate the relationship between MSDs symptoms and work ability in the shipbuilding industry. To achieve this goal, this study distributed a questionnaire for total 1,244 shipbuilding employers, and used 910 employers' reports which revealed validity for this study. The questionnaire included the MSDs symptoms report developed by the Korean Occupational Safety and Health Association(KOSHA) and the work ability index(WAI) developed by Finnish Institute of Occupational Health(FIOH). Results showed no relationship between MSDs symptoms and age, years of work and exercise. Also, the work ability was increased until 44 years old, but it was decreased after that time because of the reduced physical capacity. Meanwhile, the years of work and exercise have positive correlation with work ability. However, the results revealed significant relationships between WAI and age, years of work, task characteristics and exercise. All together, the MSDs symptoms have a close relationship with the work ability in that the work ability of workers with the MSDs symptoms was reduced. This study may suggest the needs of more efforts and attention on the MSDs prevention to increase the work ability.