• 제목/요약/키워드: old adult

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토마토의 성장과정에 따른 카탈리아제 (Catalase) 활성에 관한 연구 (Studies on the Catalase Activities of Tomato (Lycopersicum esculentum) as a Function of Age)

  • 박시원;김덕심
    • 대한화학회지
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    • 제37권12호
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    • pp.1068-1075
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    • 1993
  • 토마토(Lycopersicum esculentum)를 파종하여 1년간 성장시키면서 성장기간에 따른 잎과 뿌리의 catalase 활성 변화를 측정하였다. 뿌리에 있어서의 catalase 활성은 잎의 경우에 비해 전반적으로 매우 미약하였다. 반면에 잎의 catalase 활성은 매우 현저한 변화 양상을 나타냈는데 주로 peroxisomal 분획에 존재하였고 특히 발아 후 2주 이내의 발아초기에 76 ${\mu}mol$/ml/min의 최고 활성은 기점으로 하여 급격히 감소했다가 성장기 4 ∼ 5 개월에 즈음하여 상당히 증가된 활성을 보였으며 11 ∼ 12개월째 노화기에 가장 저조한 활성을 보였다. 이와 같이 성장시기에 따라서 변화하는 catalase 활성에 영향을 미치는 인자로서 첫째 발아기에는 glyoxylate cycle과 $\beta$-oxidation이 일어나는 glyoxisomal 반응 그리고 둘째 발아기 이후에는 광합성 반응이 각각 해당시기에 $H_2O_2$를 발생시키는 반응으로 작용할 것으로 간주된다. 이 외에도 NADPH는 불활성화된 catalase(compound II)를 다시 활성화시켜 해로운 기질인 $H_2O_2$로부터 catalase 보호제로서의 역할을 함으로써 토마토의 생장기간 전체에 걸쳐 작용하는 것으로 나타났다.

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대사증후군의 체질병증 모델 구축을 위한 예비연구 - 40대 태음인을 중심으로 - (A Pilot Study for the Construction of Sasang - Constitutionally Differentiated Model of the Metabolic Syndrome with Focus on 40 $\sim$ 49 year old Taeumin)

  • 김윤희;이준희;이의주;고병희
    • 사상체질의학회지
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    • 제21권2호
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    • pp.123-136
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    • 2009
  • 1. Objectives : This study is a pilot study to construct of metabolic syndrome model with constitutional type. We focused on the correlation of Metabolic syndrome(MetS) and ordinary symptoms with Taeumin at 40. 2. Methods : 32 subjects who had taken health examinations and diagnosis of Sasang constitution from Oct 1, 2008 to Dec 31, 2008 at Kyung-Hee medical center were included and underwent B-mode ultrasonography for measurement of intima-media thickness of common carotid arteries. MetS was defined by the criteria of the criteria of the National Cholesterol Education Program Adult Treatment Panel III. 3. Results and Conclusions : Mean intima-media thickness of common carotid artery was higher in subjects with MetS compared with control subjects(0.56$\pm$0.12 vs 0.54$\pm$0.08mm) however. The ordinary symptoms shown to differentiate the MetS group and the control group were related to "dark urine color," "dryness of eyes," and "night sweat". Therefore, these ordinary symptoms can be said to be indicators of the Taeumin with Mets syndrome.

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임신유우(姙娠乳牛)의 혈청중(血淸中) Vitamin E 농도(濃度) (Serum Vitamin E Levels in Pregnant Dairy Cows)

  • 용만중
    • 대한수의학회지
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    • 제14권2호
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    • pp.201-205
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    • 1974
  • Blood serum from 30 pregnant cows, 6 non-Pregnant cows (one month after delivery), 6 sterile cows (ovarian cyst), and 6 heifers (16 months old) were analyzed for total vitamin E concentration by the ferric chloride-bipyridyl reaction. The pregnant group was determined periodically throughout pregnancy. The results obtained were as follows: 1. The mean value of serum vitamin E level in pregnant group was $0.651{\pm}0.068(SE)mg/100ml$, in non-pregnant group $0.647{\pm}0.119(SE)mg/100ml$, in sterile group $0.488{\pm}0.053(SE)mg/100ml$, and in heifer group $0.083{\pm}0.016(SE)mg/100ml$. Samples below 0.19mg/100ml were net observed and most of the pregnants (83.3%) showed the values of 0.40 to 0.99mg/100ml during pregnancy 2. The difference of vitamin E level between pregnant group and non-pregnant group was net significant, but these trio groups showed a significantly higher value than that of sterile group. On the other hand, in heifer group was recognized significantly lower value compared with adult groups. 3. The change of serum vitamin E level in pregnant group revealed the tendency of decrease as gestation progresses and significantly dropped at the eighth month, thereafter, the value was rose slightly at the tenth month of gestation but no differences were observed. The coefficient of correlation between months and serum vitamin E levels during pregnancy was r=-0.956(p<0.01), and a regression equation was Y (serum vitamin E levels, mg/100ml)=1.034-0.063x(month).

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소아에서 발생한 전신성 모세혈관 누출 증후군(Systemic Capillary Leak Syndrome) 1례 (A Case of Systemic Capillary Leak Syndrome in a Child)

  • 이택영;정유미;강희경;하일수;정해일;최용
    • Clinical and Experimental Pediatrics
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    • 제45권10호
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    • pp.1298-1301
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    • 2002
  • 전신성 모세혈관 누출 증후군(Systemic Capillary Leak Syndrome)은 Clarkson 등이 처음 기술한 이래 50여명의 증례가 보고된 매우 드문 질환이며, 소아에서는 1995년 Ivan Foeldvari 등이 보고한 예가 유일하다. 저자들은 빈호흡, 청색증, 부종, 소변량 감소를 주소로 내원한 6세 여아에서 저혈압, 혈액농축, 저알부민혈증의 소견을 확인하고 전신성 모세혈관 누출 증후군으로 진단한 예를 문헌 고찰과 함께 보고하는 바이다.

뽕잎분말 첨가 절편 섭취가 남자 대학생의 혈청 지질 수준에 미친 효과 (The Effects of Mulberry Leaf-Jeolpyun on the Serum Lipid Level in Male University Students)

  • 김애정;김명희;김성수;곽한병
    • 동아시아식생활학회지
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    • 제10권5호
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    • pp.387-393
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    • 2000
  • Recently, it appears to have a trend of adult having weight increase in Korea. The number of obese people is increasing in Korea due to the changes of meal pattern and the lack of physical activities. Currently, obesity is the prevalent health problem in the world. The purpose of this study was to investigate the effect of mulberry leaf-Jeolpyun on the serum lipids of overweighted male university students. After 3 days of education and adaptation on this study, twenty male university students with 20.9yrs old average were fed a uniformed dormitory foodservice, and they ate constant amount of 9% mulberry leaves added-rice cake, Jeolpyun(100g) instead of boiled rice(l00g) , on each meal. Experiment was conducted during 14 days period. All meals were provided promptly. and the subejects were required to have breakfast, lunch, and dinner on weekdays. Mean height, weight, and BMI were 176.55cm, 90.OOkg, and 28.73, respectively. Although it was not very significant, body weight of the subjects appeared to be reduced after consuming the 100g substitute diet of mulberry leaf-Jeolpyun. Daily energy Intake of the subjects was 2,360.6kcal, which represents 94% of the Korean RDA. The ratio of energy obtained from carbohydrate, protein, and fat was 55: 17'27 As compared with the Korean RDA, 65 : 15 20, carbohydrate consumption was decreased but protein and fat consumption was a little bit increased. The ratio of animal-protein source was 58%, and animal-fat intake was 42%. Triglyceride concentrations decreased. but HDL-cholesterol was in the reversed manner The concentrations of HDL-cholesterol increased significantly after the 2wk-lOOg subtitute diet of mulberry leaf-Jeolpyun (p<0.05) . However, there were no significant differences in total cholesterol and LDL-cholesterol con concentrations .

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전완 원위부 심 수지 굴근에 발생한 선천성 혈관 외피세포종 - 증례 보고 - (Congenital Hemagiopericytoma in the Flexor Digitorium Profundus Muscle of the Distal Forearm - A Case Report -)

  • 김정렬;장규윤;이상용
    • 대한골관절종양학회지
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    • 제13권2호
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    • pp.146-151
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    • 2007
  • 혈관 외피 세포종은 드문 악성 혈관 종양으로 대부분 성인에서 발생한다. 영아에서 발생하는 경우는 선천성 또는 영아형 혈관 주변 세포종이라 불리우며, 아주 드물게 발생하고 성인형에 비해 양호한 예후를 보이지만 재발을 막기 위해서는 충분한 절제연을 가지고 절제 되어져야 한다. 본 증례는 출생후 1일째 내원하여, 65일째 광범위 절제술을 시행한 좌측 전완부의 혈관 외피 세포종의 증례를 보고하고자 한다.

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모바일게임 이용자의 게임 태도가 지속사용 의도에 미치는 영향 (An Effect of Gaming Behavior by Mobil Game User on Intention of Continuous Usage)

  • 심선애;임천혁;정형원
    • 한국융합학회논문지
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    • 제8권7호
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    • pp.141-149
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    • 2017
  • 본 연구는 모바일게임 이용자의 게임 태도와 게임 지속사용 의도 간의 관계를 알아보고자 하였다. 태도는 어떤 대상이나 사태에 반응하는 행동을 말하는 것으로 보편적으로 일관성 있는 행동을 하게 되고 또한 이후의 반응을 예측할 수 있기 때문이다. 연구를 위해 한국과 중국의 20세 이상 성인 모바일게임 이용자를 대상으로 설문조사를 시행하였으며, 수집된 데이터는 통계패키지 프로그램인 SPSS 20.0을 사용하여 위계적 다중회귀분석을 시행하였다. 연구결과 첫째, 게임 태도를 고려하지 않는다면, 남자일수록, 대한민국 국적이 아닐수록(중국 국적일수록) 지속사용 의도가 높게 나타났다. 둘째, 모바일게임 이용자의 게임 태도가 지속사용 의도에 미치는 영향을 알아본 결과 인지적 태도, 행동적 태도는 모두 유의한 정(+)의 상관관계를 나타내는 것으로 확인되었다.

Effect of Valproic acid, a Histone Deacetylase Inhibitor, on the Expression of Pluripotency and Neural Crest Specific Marker Genes in Murine Multipotent Skin Precursor Cells

  • Hong, Ji-Hoon;Park, Sang-Kyu;Roh, Sang-Ho
    • International Journal of Oral Biology
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    • 제35권4호
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    • pp.209-214
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    • 2010
  • Cells that have endogenous multipotent properties can be used as a starting source for the generation of induced pluripotent cells (iPSC). In addition, small molecules associated with epigenetic reprogramming are also widely used to enhance the multi- or pluripotency of such cells. Skinderived precursor cells (SKPs) are multipotent, sphereforming and embryonic neural crest-related precursor cells. These cells can be isolated from a juvenile or adult mammalian dermis. SKPs are also an efficient starting cell source for reprogramming and the generation of iPSCs because of the high expression levels of Sox2 and Klf4 in these cells as well as their endogenous multipotency. In this study, valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, was tested in the generation of iPSCs as a potential enhancer of the reprogramming potential of SKPs. SKPs were isolated from the back skins of 5-6 week old C57BL/6 X DBA/2 F1 mice. After passage 3, the SKPs was treated with 2 mM of VPA and the quantitative real time RT-PCR was performed to quantify the expression of Oct4 and Klf4 (pluripotency specific genes), and Snai2 and Ngfr (neural crest specific genes). The results show that Oct4 and Klf4 expression was decreased by VPA treatment. However, there were no significant changes in neural crest specific gene expression following VPA treatment. Hence, although VPA is one of the most potent of the HDAC inhibitors, it does not enhance the reprogramming of multipotent skin precursor cells in mice.

소아에서 골절된 하악과두의 골개조 양상에 관한 임상 및 방사선학적 연구 (A CLINICO-RADIOLOGIC STUDY OF BONY REMODELING OF THE FRACTURED CONDYLES IN CHILDREN)

  • 조정신;박창서
    • 치과방사선
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    • 제25권2호
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    • pp.471-482
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    • 1995
  • Bony remodeling pattern of condyle fractures in children are different from in adult for growing of condyle, also might affect treatment and prognosis of the condyle fracture. Subjects of this clinical and radiologic study were 26 temporomandibular joints diagnosed as condyle fracture in 23 patients under 15 years old age. They were treated with conservative method at Dental Hospital of Yonsei University from Jan., 1986 to Oct., 1994. Bony remodeling related with fracture pattern was evaluated. The results obtained are as follows: 1. The ratio of male to female in patients with condyle fracture was 1 : 0.9 and the difference of sex ratio was not noted. Comparing with preschool-age group and school-age group, age frequency was higher in preschool-age group(83%). 2. Fallen down(54%) was the most frequent cause of condyle fractures. Traffic accident and slip down were followed. 3. The most common clinical sign of condyle fractures was tenderness to paipation09 cases). Mouth opening limitation07 cases), swelling(7 cases), malocclusion(3 cases) were next in order. 4. According to sites of condyle fractures, unilateral fractures were in 20 patients and bilateral fractures in 3 patients, therefore total 23 patients-26 cases of condyle fracture were observed. According to fracture distribution, condyle fractures were in 10 patients(44%). Condyle fractures with symphysis fracture(9 patients, 39%), condyle fractures with ascending ramus fracture(2 patients, 9%), condyle fracture with mandibular body fracture(1 patient, 4%), and condyle fractures with mandibular angle fracture(1 patient, 4%) were followed. 5. In displacement pattern of fractured fragment of mandibular condyle, dispiacement(17 cases, 66%) was most common. Dislocation(5 cases, 19%) and deviation (4 cases, 15%) were next in order. 6. During the observation period of fractured condyles, remodeling patterns of fracture sites related with articular fossa were observed with usual condylar shape in 23 cases and with prominently different shape in 3 cases.

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한복에 대한 태도를 중심으로 한 사회심리학적 의복연구-서울의 성인여성을 중심으로- (Attitude Toward Traditional Korean Clothing as Related to Selected Social Psychological Factors)

  • 강혜원
    • 대한가정학회지
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    • 제17권3호
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    • pp.1-11
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    • 1979
  • The purposes of this study were ; (1) to investigate attitudes toward Korean clothing in relation to 3 aspects of clothing behavior , and in relation to attitudes toward women's role, age and education, and (2) to ascertain the extent to which Korean clothing was used and valued. Clothing measures consisted of statements dealing with positive and negative attitudes toward psychological and practical aspects of Korean clothing, frequency of use of Korean clothing, and modesty and confirmity -individuality measure. The measure of attitudes toward women's role consisted of items selected form the Inventory of Feminie Values and the Sex Role Ideology Scale. Product-moment correlation was used to analyze the data which consisted of the responses of 700 adult Korean women to questionnaires administered by the researcher. The results obtained are as follows : 1) Positive attitudes toward Korean clothing for both psychological and practical aspects were, (1) related negatively to nontraditional attitudes toward women's role and education, and (2) related positively to age, frequency of wearing Korean clothing and modesty in clothing. 2) Negative attitudes toward Korean clothing for practical aspect was related negatively to age and education , whereas, the psychological aspect was negatively related to attitudes toward women's role. 3) Conformity-individuality in clothing was related positively to attitudes toward women's role and education. 4) Modesty in clothing was related negatively to attitudes toward women's role and education, conformity individuality, and was related positively to age. 5) In 1945 most of the subjects over 51 -year-old wore Korean clothing always or most of time, whereas, about 1/3 of them wore the same in 1976 , Only 4% of the total participants regardless of their ages wore Korean clothing for everyday life in 1976. 6) In general , highly positive attitudes toward Korean clothing were found on psychological aspect, whereas, highly negative attitudes toward Korean clothing were found on practical aspect.

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