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Analysis of inter-fraction and intra-fraction errors during volumetric modulated arc therapy in Pancreas Ca (호흡 동조 췌장 암 용적 세기조절 회전 치료 시 Inter-fraction Intra-fraction 분석)

  • Jo, Young Pil;Seo, Dong Rin;Hong, Taek Kyun;Kang, Tae Yeong;Beck, Geum Mun;Hong, Dong Ki;Yun, In Ha;Kim, Jin San
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.2
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    • pp.247-256
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    • 2014
  • Purpose : To assess target motion during radiotherapy by quantifying daily setup errors and inter-fractional and intra-fractional movements of pancreatic fiducials. Materials and Methods : Eleven patients were treated via stereotactic body radiotherapy (SBRT) with volumetric modulated arc therapy. Bony setup errors were calculated using cone beam computed tomography (CBCT). Inter-fractional and intrafractional fiducial (seed) motion was determined via cone beam computed tomography (CBCT) projections and orthogonal fluoroscopy. Results : Using an off-line correction protocol, setup errors were 0.0 (-1.7-4.0), 0.3 (-0.5-3.0), and 0.0 (-4.1-6.6) mm for the left-right, anterior-posterior, and superior-inferior directions respectively. Random inter-fractional setup errors in the mean fiducial positions were -0.1, -1.1, and -2.3 mm respectively. Intra-fractional fiducial margins were 9.9, 7.8, and 12.5 mm, respectively. Conclusion : Online inter-fractional and intra-fractional corrections based on daily kV images and CBCT expedites SBRT of pancreatic cancer. Importantly, inter-fractional and intra-fractional motion needs to be measured regularly during treatment of pancreatic cancer to account for variations in patient respiration.

Experimental Study on Underwater Transient Noise Generated by Water-Entry Impact (입수 충격 수중 순간 소음에 대한 실험적 연구)

  • Jung, Youngcheol;Seong, Woojae;Lee, Keunhwa;Kim, Hyoungrok
    • The Journal of the Acoustical Society of Korea
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    • v.33 no.1
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    • pp.10-20
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    • 2014
  • To study the water-entry impact noise, on-board experiment using a small launcher firing various objects was performed in the Yellow Sea. As the launcher fires a cylindrical object from the ship vertically, generated noise is measured with a hydrophone on the starboard of Chung-hae, Marine surveyor. Three types of cylindrical objects, which have noses of flat-faced, conical, and hemisphere, were used during the experiment. The measured noise exhibits a time-dependency which can be divided into three phases: (1) initial impact phase, (2) open cavity flow phase, (3) cavity collapse and bubble oscillation phase. In most cases, the waveform of bubble oscillation phase is dominant rather than that of initial impact phase. Pinch-off time, where a cavity begins to collapse, occurs at 0.18 ~ 0.2 second and the average lasting time of bubble was 0.9 ~ 1.3 second. The energy of water-entry impact noise is focused in the frequency region lower than 100 Hz, and the generated noise is influenced by the nose shapes, object mass, and launching velocity. As a result, energy spectral density on the bubble frequency is higher in the order of flat-faced, conical, hemisphere nose, and the increase of initial energy raises the energy spectral density on the bubble frequency in the cylinder body of same shape. Finally, we compare the measurements with the simulated signals and spectrum based on the bubble explosion physics, and obtain satisfactory agreements between them.

Male Parental Care, Egg and Larval Development of the Smoky Damselfish, Chromis fumea (Pisces: Pomacentridae) (연무자리돔, Chromis fumea (Pisces: Pomacentridae)의 산란보호, 난발생 및 자어의 형태발달)

  • Kim, Jin-Koo;Kim, Yong-Uk;Park, Jin-Woo
    • Korean Journal of Ichthyology
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    • v.13 no.3
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    • pp.166-172
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    • 2001
  • Parental care of eggs of Chromis fumea (Tanaka) was observed by Skin Scuba gear in August 1995 off Cheju Island. The eggs and larval development were observed in the laboratory at Pukyong National University, Pusan. Eggs were deposited on a flat surface of hard substratum and formed a plain sheet of one layer of eggs. Males showed parental care of the eggs by hovering over the nest and attacking other fishes that approached the nest. The spawned eggs were transparent, elliptical in shape and measured 0.73~0.88 mm in long axis and 0.50~0.56 mm in short axis. An analysis by T-test of the long axis of the egg with time showed a significant difference (p<0.01). However, there was no significant difference in short axis with time. Eggs were reared at water temperatures of $23.0{\sim}25.5^{\circ}C$ and took about 4~5 days from embryonic body stage to hatching. The newly hatched larvae were 1.10~1.61 mm in notochord length (NL) had 21 myomeres, has closed mouth but open anus, preanus length was 45.8% of NL. Melanophores were distributed on the occipital region of head, the eye, the peritoneal region, and along the ventral contour. The larvae absorbed the yolk material and oil globule in 3~4 days after hatching and became postlarvae. On the third day after hatching, the larvae had attained 1.9~2.4 mm in NL, had 25 myomeres, and showed rapid growth. By the ninth day after hatching, the larvae had attained 2.9 mm in NL, had an swimbladder in the dorsal margin of ventral region, the preanus length was 37.9% of NL, and their melanophores were enlarged and reduced in number.

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Repair and Restoration of Joseon Historical Document Box (조선왕조 실록함의 수리복원)

  • Yi, Yonghee;Park, Junghae;Park, Suzin
    • Conservation Science in Museum
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    • v.15
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    • pp.122-137
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    • 2014
  • The National Museum of Korea own a historical document box K976 that was once used to store Joseon Wangjo Sillok Annals of the Joseon Dynasty of the Joseon Dynasty. The rectangular box has a lid, and the entire surface is varnished with black lacquer. The wood of the box had become warped and the upper part of the wooden frame had been damaged. In some areas, the paint was flaking off, exposing the underlying wood, and an iron ring that connected the lid to the body of the box was missing. Thus, in 2013, Conservation Science Department in National Museum of Korea began to repair and restore the Joseon document box. Before the treatment, analyses were conducted to examine the box's structure, damaged parts, species of wood, and lacquering techniques. The wood was found to be that of a linden tree. As for the lacquering technique, the surface of the box was first coated with a layer of lacquer and bone ash, and then covered with Korean traditional paper. Next, the box was painted with a layer of mud and ashes, followed by a layer of black pigment mixed with soot, and then varnished again with lacquer.

Convergent Influence Effect on the High - Quality CPR of 119 Paramedics by Wearing Personal Protective Equipment by Level (구급대원의 수준별 개인용 보호구 착용에 따른 심폐소생술 품질에 미치는 융합적인 영향)

  • Shin, Dong-Min;Cho, Byung-Jun;Yang, Hyun-Mo;Jeon, Seong-Man;Han, Yong-Taek
    • Journal of the Korea Convergence Society
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    • v.11 no.4
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    • pp.71-78
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    • 2020
  • The purpose of this study is to investigate the effect of wearing clothes, Level B, and Level C PPE on normal CPR using mannequins. The paramedics who participated in this experiment were 20 paramedics with more than 5 years of experience in firefighting area C. It was found that chest compressions in the process that hand off time was 11.9 seconds in the uniform wearing group, 11.4 seconds in the level C PPE wearing group, and 13.1 seconds in the SCBA wearing group. In other words, wearing personal protective equipment prevents the movement of paramedics and uses compensatory movements, which may increase the difficulty of efficient first aid. If this situation persists, it may cause fatigue and damage to the body of paramedics. Rescue and paramedics should wear level personal protective equipment in case of emergencies and conduct rescue and CPR training.

Study on the Improvement of Bovine Somatic Cell Nuclear Transfer Technique (소 체세포 핵이식기술의 효율 증진에 관한 연구)

  • 양윤희;최종엽;이상영;박춘근;양부근;김정익;정희태
    • Korean Journal of Animal Reproduction
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    • v.27 no.3
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    • pp.233-240
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    • 2003
  • This study was conducted to examine the effects of oocyte maturation period, phytohemagglutinin-P (PHA-P) treatment and activation agent on the enucleation, fusion, activation or in vitro development of bovine nuclear transfer embryos. Bovine oocytes were enucleated at 16∼24 h of in vitro maturation (IVM). Adult ear skin cells treated or non-treated with PHA-P were transferred into enucleated oocytes. Reconstituted oocytes treated or non-treated with PHA-P were fused by a pulse of 1.5 kV/cm for 30 $\mu$sec. Fused oocytes were activated with a combination of calcium ionophore (A23187) and cycloheximide (CHXM) or dimethylaminopurine (DMAP), and cultured in vitro for 7∼9 days. Enucleation rate was significantly increased when oocytes were matured for 16∼18 h (70.2∼92.3%, P<0.05) compared to that of oocytes were matured for 20∼24 h (44.3∼53.4%). The location of metaphase-II plate was far off from the 1st polar body as maturation time was increased. PHA-P treatment of donor cells or reconstituted oocytes significantly improved fusion rate (P<0.05). Cleavage and blastocyst formation rates were significantly increased after activation with a combination of A23187 and DMAP (78.6% and 32.9%, respectively) compared to those of embryos activated with a combination of A23l87 and CHXM (48.5 and 15.2%, respectively). From the present result, it is suggested that high enucleation efficiency can obtained by using oocytes matured for 18 h. It also shows that PHA-P treatment can improve the fusion rate, and activation with a combination of A23187 and DMAP can enhance the embryo development.

SMITH-MAGENS SYNDROME (SMS) : A CASE REPORT (Smith-Magenis Syndrome (SMS) 환아의 증례 보고)

  • Kim, Eun-Young;Lee, Keung-Ho;Choi, Yeong-Chul
    • Journal of the korean academy of Pediatric Dentistry
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    • v.30 no.3
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    • pp.341-347
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    • 2003
  • Smith-Magenis syndrome (SMS) is a clinically recognizable multiple congenital anomaly and mental retardation syndrome caused by an interstitial deletion of chromosome 17 p11.2. Physical features include short stature, characteristic facial appearance: flattened mid-face, down-turned mouth, prominent and often rosy cheeks; prominent jaw in older children and adults, chronic ear infections, hearing impairment, eye problems, including: strabismus (an eye which turns in or out) and myopia (nearsightedness), hoarse voice, short fingers and toes, heart defects or murmurs, problems related to the urinary system, scoliosis (curvature of the spine), an unusual gait (walking pattern), and decreased sensitivity to pain. Behavioral and developmental characteristics include speech delay and articulation problems, developmental delay, learning disability, mental retardation, hyperactivity, self-injury, including: head banging; hand biting; picking at skin, sores and nails; pulling off finger- and toenails; inserting foreign objects into ears, nose, or other body orifices, explosive outbursts, prolonged tantrums, destructive and aggressive behavior, excitability, arm hugging or hand squeezing when excited. This report is the case of a Korean 3-year-3-month old male with Smith-Magenis syndrome referred from local clinic for the treatment of dental caries. The patient was treated by physical restraint after prophylatic administration of antibiotic(Amoxacillin 50mg/kg).

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A survey of the state of nutrition & the clinic in Rural Korea (농촌영양실태(農村營養實態)와 임상(臨床)에 관(關)한 조사(調査) (II))

  • Lee, Geum-Yeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.3 no.1
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    • pp.47-51
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    • 1974
  • 1. As the low standard of living of the people who live in both the model and compared villages, is almose similar to each other, the state of their food intaking has nearly the same degree. 2. The villagers of the two kinds of village mentioned above do not cast off their traditional eating habits getting an energy from rice and vegetarian diet. They, however, have been so much interested in the problem of birth control that they have a few children in less than four-year-old. We have to go on the problems of driving a reasonable family plan, and replacing the traditional food life by taking a fatty food. 3. Their pool life forces them to have an over work for supporting their family. Even though they take much Fe from grains and vegetables day after day, Fe does not give a great influence on making Hb (Erythrocyte) in a body. Accordingly most of them have developed symptoms of anemia. This research, comparing with the research results of Ewha University and Seoul Medical College shows much lack of Hb. So it is need for them to take a large quantity of animal protain and make a healthful habit by reforming their food life.

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SUPPLY-DEMAND, COMMERCIAL DISTRIBUTION AND TRANSACTION OF THE CULTURED TUNA IN JAPAN - EMPHASIZING ON THE GLOBAL EXPANSION OF THE TUNA-FARMING BUSINESS -

  • Yamamoto, Naotoshi;Kameda, Kazuhiko;Nishida, Akari;Kitano, Shinichi
    • The Journal of Fisheries Business Administration
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    • v.39 no.1
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    • pp.87-114
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    • 2008
  • The cultured tuna production which has suddenly expanded at the short time and the demand for it attract attention. Farming mode, distribution transactions, change of the market (domestic and international) and the price trend are reviewed from the Japan's position which is the biggest consuming country. This paper tries to describe the current status of the food system related to the cultured tuna. Japanese government began the development of the tuna culture technology in 1970. It was by the Fisheries Agency's project. Kinki University which is the large scale private university in Japan participated in the project. After that, 32 years have passed. Kinki University established the full farming of the bluefin tuna in August, 2002. On the other hand, in 1974, one Japanese private enterprise began its tuna farming business in Canada. Kinki University gave this company technical cooperation. Also, in the early stages of the 90s, as for the policy of the overseas fishery cooperation foundation, it supported the tuna farming business in Australia. It is very clear to understand that the long-term technological-development has supported the take-off scene of the tuna culture business not only in foreign countries but also in Japan. The total shipment scale of the cultured tuna expanded very much within about 10 recent years. However, the decrease of the wild tuna catch, the reinforcement of the fisheries regulation and the tuna body to dwarf are remarkable now. Under the condition as the mentioned above, Japan's tuna consumption, especially, in the market at the fatty meat of tuna of the cultured tuna is building up firm status. At present, the Mediterranean Sea coastal countries, Australia, Mexico and Japan have the tuna farming sites. Australia farms the southern bluefin tuna. The others do the bluefin tuna. About for 3 years, Japan farms the juvenile of the tuna. The global production areas are as follows. 8 coastal countries of the Mediterranean Sea; 18,000 tons (61 % of the cultured tuna quantity in foreign countries), Mexico; 4,500 ton (15%), Australia; 7,000 tons (24%). In 2003, Japan has 32 managements and 39 offices for tuna farming. In Japan, Kyushu and Okinawa district, the share shows itself as 80 % of the domestic production quantity. Especially, the share of Amami-oshima Island in Kagoshima Prefecture exceeds 60 %. Therefore, this island has the maximum production scale of Japan. The amount of supply of BT and SBT was 56,000 tons in 2004. In Abroad, the tuna farming business forms a fixed connection between the importer and the wholesaler which have their office in Japan. In the field of the capital composition, the payment in advance, transaction and the way of settlement, each maintains their fixed relation. The market conditions of the cultured tuna are supported by "the decline of price level" and "the expansion of the general public consumption segment". These lead a team merchandising, and it is supported by the fixed business connection of each. This makes the profit of each business which are on the cultured tuna distribution. However, they have competition on the power balance among them.

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Developing a water discharge anchor & trap bolt to prevent basic salt from penetrating to harbor structures (해수 염기 침투방지를 위한 항만구조물 보수보강용 물배출 앵커 및 트랩볼트 개발에 관한 연구)

  • Ock, Jong-Ho;Moon, Sang-Deok;Lee, Hwa-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.3
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    • pp.535-541
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    • 2018
  • Most construction methods for the repair and reinforcement of old reinforced concrete harbor structures involve a process of applying a fiber complex or fiber complex panel just like wallpaper to the bottom of structures, such as slabs or beams. On the other hand, these techniques result in the sealing of repaired and reinforced portions of the structures by the fiber products, preventing moisture, such as rainwater entering the structures through the upper surfaces of the slabs or beams from being released, and causing the entire concrete covering of the structures to be peeled off in the long run. To prevent this, it is necessary to develop a technique to protect the basic salt from the sea water from penetrating into the structures while expelling the water absorbed in the structures swiftly. This study attempted to solve the problem by modifying the anchor bolts currently used to repair and reinforce the port structure. That is, by drilling holes into the body of anchor bolts and modifying the caps of the bolts to produce a structure that would let the water flow like a toilet trap, the moisture inside of the structure could be drained through the holes in the anchor bolts. The water discharge anchor bolts developed were tested and observed for 6 months; the water was discharged in 73% of the anchors (200 anchor installation, 145 anchors).