• Clinical and Experimental Pediatrics
• /
• v.63 no.3
• /
• pp.110-114
• /
• 2020

Background: Subclinical hypothyroidism (SH) is a common condition in obese children. However, its effect on glucose and lipid metabolism in obese children remains controversial. Purpose: The present study aimed to investigate the association between SH and metabolic parameters. Methods: A total of 215 obese children and adolescents aged 6-18 years were included in this retrospective cross-sectional study. The patients' anthropometric measurements such as thyrotropin (TSH), free thyroxine (fT4), fasting plasma glucose, and insulin levels, as well as homeostasis model assessment for insulin resistance (HOMA-IR) index, and lipid profiles were evaluated. The patients were allocated to the SH group (fT4 normal, TSH 5-10 mIU/L) (n=77) or the control group (fT4 normal, TSH<5 mIU/L) (n=138). The glucose and lipid metabolisms of the 2 groups were compared. Results: SH was identified in 77 of 215 patients (36%). Mean body mass index was similar in both groups. The mean serum insulin, HOMA-IR, and triglyceride (TG) levels were higher and the mean high-density lipoprotein cholesterol level was lower in the SH group than in the control group (P=0.007, P=0.004, P=0.01, and P=0.02, respectively). A positive correlation was observed between TSH level and insulin level, HOMA-IR, and TG level. Conclusion: SH was identified in some of the obese children and adolescents. A clear association was observed between SH, insulin resistance, and dyslipidemia in obese children.

• Journal of Korean Medicine for Obesity Research
• /
• v.2 no.1
• /
• pp.53-61
• /
• 2002

Objective: Obesity is closely related to several factors such as genetic factors, energy intake and energy expenditure. It was said that alcohol & food habits were important to formation of obesity. The purpose of this study are to find out the alcohol & food habitual characteristic of obese adult men and to promote the health of these men. Method: From May, 2000 to November, 2001, We collected 75 eases obese patients, who visited to the Health Examination Center Dept. of Kangnam oriental medicine hospital, Dongguk University who took the health examination, and control group who were matched by age and sex. We investigated the alcohol & food habits by questionnaire. Results and Conclusions: 1. The patients over BMI 25 were in excess of the standard of obesity such as Modified Broca $^{\circ}{{\O}}s$ Index. Percent Body Fat, Abdominal Fat Distribution. But, the patients below BMI 20 were normal range of obesity degree. 2. Abdominal Fat Distribution was increased according to age and physical activity was decreased in obese group. 3. The mean of total calory by alcohol in a month was 4324.6kcal in obese group while control group was 2206.8kcal. 4. In the comparison of food habit, obese group is higher than control group in 7 articles of the 13 articles which influenced obesity.

• Journal of Pharmacopuncture
• /
• v.24 no.2
• /
• pp.54-58
• /
• 2021

Objectives: The purpose of this study is to investigate the effects of aerobic exercise and acupuncture treatment in obese patients. Methods: The effects of exercise in obese patients receiving acupuncture therapy were investigated in this retrospective, case-controlled study in which subjects complying with exercise were enrolled in the case and non-compliers were enrolled in the control group. Results: There was a statically significant weight loss in both the study case group (94.39 ± 20.36; 88.91 ± 19.00; n = 22; p = 0.001) and the control group (103.18 ± 21.92; 99.56 ± 21.92; n = 34; p = 0.001) after 3 months. Weight loss occurred in all 22 patients in the case group. In the control group, while weight loss occurred in 27 of the 34 patients, weight gain occurred in three patients. Conclusion: In conclusion, the addition of modalities such as acupuncture, exercise and diet may provide effective improvement in weight control.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.5
• /
• pp.1411-1418
• /
• 2005

Obesity is not classed in general psychiatry disease. But, psychoneurotic factor has been known to be a risk factor of obesity. In order to evaluate and understand the psychoneurotic state on obese patient, this study used Minnesota Multiphasic Personality Inventory(MMPI). Total patients were classified into 3 or 5 clusters. MMPI scores were compared according to education, BMI and Sasang Constitution. Multiple regression analysis were used for psychological factor on obese patients by age, height, weight, education, percent body fat, fat distribution, BMI. Based on this study, it was no significantly difference by education level, BMI, sasang(四象) constitution except L profile according to BMI. These result is different from our general recognition of the psychoneurotic state on obese patient. Therefore, the bigger sample study is needed.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.22 no.5
• /
• pp.470-478
• /
• 2019

Purpose: The incidence of non-alcoholic fatty liver disease (NAFLD) in children is gradually increasing. The aim of this study was to investigate the use of serum adiponectin and soluble adiponectin receptor 2 (soluble Adipo R2) levels for the diagnosis of fatty liver disease in obese and overweight children. Methods: The study included 51 obese and overweight children between the ages of 6 and 18 years diagnosed with NAFLD using ultrasonography and 20 children without fatty liver disease. Patients whose alanine transaminase level was two times higher than normal (${\geq}80U/L$) were included in the non-alcoholic steatohepatitis (NASH) group. Results: NASH was observed in 11 (21.6%) of the patients with NAFLD. The incidence of obesity was higher in patients with NASH (80% and 45%, p=0.021). While the adiponectin levels were similar in patients with NAFLD and those without, they were below the normal level in the whole study group. Adiponectin and soluble Adipo R2 levels of patients with NASH were lower than those in patients without NASH; however, this difference was not statistically significant (p=0.064 and p=0.463). Soluble Adipo R2 levels in obese patients with NAFLD were higher than those in obese children without NAFLD (p<0.001). Conclusion: Soluble adiponectin receptor 2 level is a noninvasive marker that can be used for the diagnosis of NAFLD in obese children.

• The Journal of Pediatrics of Korean Medicine
• /
• v.19 no.2
• /
• pp.1-11
• /
• 2005

Objectives : The purpose of this study is to investigate the effect of fasting therapy on the changes of body composition in obese adolescents. Methods : We examined the body composition of obese adolescents three times; before fasting, on the second refeeding day, two or four weeks later. Results : Body weight, body mass index(BMI), basal metabolic rate(BMR) and lean body mass (LBM) were decreased during the fasting, whereas percent-fat was increased. After fasting, patients have the dietary period. During this period BMR and LBM were increased and the decrease of percent-fat was continued. Conclusions : It seems that fasting therapy with keeping up well-controlled dietary period and receiving oriental medical management can be useful to decrease percent-fat in obese patients.

• Asian Spine Journal
• /
• v.12 no.6
• /
• pp.1085-1091
• /
• 2018

Study Design: Case-control. Purpose: To determine optimal cut-off value for body mass index (BMI) in predicting surgical success in patients with lumbar spinal canal stenosis (LSCS). Overview of Literature: BMI is an essential variable in the assessment of patients with LSCS. Methods: We conducted a prospective study with obese and non-obese LSCS surgical patients and analyzed data on age, sex, duration of symptoms, walking distance, morphologic grade of stenosis, BMI, postoperative complications, and functional disability. Obesity was defined as BMI of ${\geq}30kg/m^2$. Patients completed the Oswestry Disability Index (ODI) questionnaire before surgery and 2 years after surgery. Surgical success was defined as ${\geq}30%$ improvement from the baseline ODI score. Receiver operating characteristic (ROC) analysis was used to estimate the optimal cut-off values of BMI to predict surgical success. In addition, correlation was assessed between BMI and stenosis grade based on morphology as defined by Schizas and colleague in total, 189 patients were eligible to enter the study. Results: Mean age of patients was $61.5{\pm}9.6years$. Mean follow-up was $36{\pm}12months$. Most patients (88.4%) were classified with grades C (severe stenosis) and D (extreme stenosis). Post-surgical success was 85.7% at the 2-year follow-up. A weak correlation was observed between morphologic grade of stenosis and BMI. Rates of postoperative complications were similar between patients who were obese and those who were non-obese. Both cohorts had similar degree of improvement in the ODI at the 2-year followup. However, patients who were non-obese presented significantly higher surgical success than those who were obese. In ROC curve analysis, a cut-off value of ${\leq}29.1kg/m^2$ for BMI in patients with LSCS was suggestive of surgical success, with 81.1% sensitivity and 82.2% specificity (area under the curve, 0.857; 95% confidence interval, 0.788-0.927). Conclusion: This study showed that the BMI can be considered a parameter for predicting surgical success in patients with LSCS and can be useful in clinical practice.

• Journal of Korean Physical Therapy Science
• /
• v.7 no.2
• /
• pp.683-696
• /
• 2000

To examine the blood lipids, muscle strength and flexibility at low back, and muscle strength in the knee joint, 44 women, who were diagnosed as chronic low back pain patients and aged between 40 to 50 years old, were recruited as the subjects. The women were divided into two groups: 1) body fat content less than 25% and 2) body fat content more than 30%. The results were: 1) No differences were found between two groups in blood lipids status. 2) The total cholesterol were less 3.78% in the normal group than the obese group. 3) The HDL-cholesterol were higher 4.85% in the normal group than the obese group. 4) The TG were less 13.1% in the normal group than the obese group. 5) No differences were found between two groups in muscle strength and flexibility 6) No differences were found between two groups in the peak torque of knee joint 7) The total work of the knee joints were higher in the normal group than the obese(P<.05). 8) The abdominal strength were higher 34.04% in the normal group than the obese group. 9) The flexibility of low back were higher 44.54% in the normal group than the obese group.

• Journal of Oral Medicine and Pain
• /
• v.47 no.3
• /
• pp.135-143
• /
• 2022

Purpose: This study aimed to evaluate polysomnographic and cephalometric characteristics of patients with OSA according to obesity level based on the World Health Organization (WHO) Asian-Pacific BMI criteria. Methods: One hundred and thirty-one consecutive patients with obstructive sleep apnea (OSA) were evaluated using standard level 1 polysomnography and cephalometric analyses. The subjects were categorized into normal, overweight and obese groups according to the WHO Asian-Pacific BMI criteria. Respiratory indices and cephalometric parameters were compared among groups. Results: The 131 patients consisted of 111 males and 20 females, with a mean age of 44.1±12.4 years. The mean value of BMI was 25.3±3.4 kg/m² for all subjects, 20.6±2.2 kg/m² for normal (n=27), 24.0±0.5 kg/m² for overweight (n=33) and 27.6±2.2 kg/m² for obese (n=71). The obese group had a significantly higher apnea-hypopnea index (AHI) and respiratory arousal index and lower oxygen saturation level than the normal group (p<0.05). Total AHI, mean oxygen saturation level and respiratory arousal index were significantly correlated with BMI (p<0.001). A longer soft palate and anterior position of the hyoid bone were significantly correlated with BMI level (p ≤0.05). Conclusions: Obese patients have a higher risk of compromised craniofacial skeletal features and soft tissue structures, and severe OSA than non-obese patients.

• Journal of Trauma and Injury
• /
• v.35 no.4
• /
• pp.240-247
• /
• 2022

Purpose: Studies on the relationship between obesity and injuries, especially those sustained in pedestrian traffic accidents, are lacking. We aimed to assess the effects of obesity on the severity of injury at the time of admission to the emergency room in patients who experienced pedestrian traffic accidents. Methods: This study included trauma patients registered in the Korean Trauma Database from July 1, 2018 to December 31, 2020, whose mechanism of injury was pedestrian traffic accidents and who were treated at a single institution. Those aged below 15 years were excluded. Patients were assigned to nonobese and obese groups based on a body mass index of 25 kg/m². An Injury Severity Score of 25 or greater was considered to indicate a critical injury. Results: In total, 679 cases of pedestrian traffic accidents were registered during the study period, and 543 patients were included in the final analysis. Of them, 360 patients (66.3%) and 183 patients (33.7%) were categorized as nonobese and obese, respectively. The median age was significantly higher in the nonobese group than in the obese group (60 vs. 58 years). Multivariate analysis demonstrated that the odds ratio for critical injury in obese patients was 1.59 (95% confidence interval, 1.01-2.48) compared with nonobese patients. Conclusions: Obesity affected the likelihood of sustaining severe injuries in pedestrian traffic accidents. Future studies should analyze the effects of body mass index on the pattern and severity of injuries in patients with more diverse injury mechanisms using large-scale data.