• 생약학회지
• /
• 제33권4호통권131호
• /
• pp.312-318
• /
• 2002

Effect of the acid hydrolysate of silk fibroin on obesity was investigated in obese(057BL/KsJ-db/db) mice. After 8 weeks feeding of 1%(w/w) or 3%(w/w) fibroin hydrolysate, the extents of reduction in body weight were significantly higher than that of obese control. The weight reduction in female mice was higher than that in male mice. Plasma leptin in male mice increased up to 1.8-fold higher level than obese control by feeding hydrolysate. In case of female mice, however, it rather decreased with increased feeding concentration of hydrolysate. From the results of high glycine and serine contents of peptide fractions contained in fibroin hydrolysate, it was inferred that fibroin peptides might affect xylosyltransferase(XT) activity on chondroitin sulfate synthesis causing to change susceptibility of adipocytes to hormones such as insulin followed by the reduced leptin synthesis in female mice. The result of the higher lipolysis in hydrolysate-fed group than obese control indicated that the reduction in body weight was due to the increased lipolytic activities in male and female mice in common.

• Preventive Nutrition and Food Science
• /
• 제2권2호
• /
• pp.144-148
• /
• 1997

Insulin secretory response to various calcium concentrations was investigated in 10- to 12-week old male lean and obese Zucker rats using an in vitro pancreatic perfusion procedure. There was no significant difference in insulin secretion response to low, medium, and high calcium concentrations in the lean rat. However, the obese rat shows a characteristics of hypersecretion of insulin. The obese rat pancreas perfused with the low calcium concentration released as low insulin as the lean rat. When perfused with the medium calcium concentration, th obese rat pancreas released twice as much insulin as the lean rat. eh hypersecretory phenomenon was also seen in the obese rat pancreas perfused with the high calcium concentration during the first phase of erfusion period, but his phenomenon was gradually diminished during he second phase of perfusion period. These results indicate that there may be a selective insulin secretory response to the extracellular calcium in he obese Zucker rat pancreas.

• 대한지역사회영양학회지
• /
• 제11권6호
• /
• pp.683-694
• /
• 2006

The purpose of this study was to determine the body weight control, food habits and nutrient intakes according to the obese index in male middle school students. This study was carried out through questionnaires and measurement by body fat analyzer (Inbody 4.0). The subjects were 275 male middle school students in Iksan. Chonbuk province. The average age, height, weight, and BMI of the subjects were 14.4 years old, 167.8 cm, 60.2 kg and $21.3kg/m^2$, respectively. Seventeen point one percent of the subjects were the underweight group, 47.6% were the normalweight group, and 35.3% were the overweight group by the classification of the Korean Pediatrics Society standard. Body fat of underweight, normalweight, and overweight were 16.1%, 19.0%, and 26.6%, respectively. Thirty one point nine percent of underweight, 39.7% of normalweight. and 31.9% of overweight had misperceptions of their weight (p<0.001). Sixty two point two percent of the males were dissatisfied with their body weight, and 55.3% of the whole tried to reduce their body weights. Even though they were normalweight, half of them dissatisfied with their weight. The source of weight control method was friends and family, TV radio, Internet, and school nutrition education, in order. The subjects exercised 3.4 days per week, 70.2 minutes per day, but it was not different significantly by the obese index. Forty percent of the subjects had meals fast, 58.5% of them have biased food habits even if they didn't differ by the obese index. Activity rate was different by the obese index significantly (p < 0.05), the number of severe activity was most in underweight. In conclusion, nutrition education programs should contain the necessity of normalweight, and regularity of lift habits and activities for energy expenditure in overweight students. It made them to recognize their weight correctly, establish healthy body images, and raise the ability to promote health and improve nutritional status.

• Journal of Nutrition and Health
• /
• 제23권6호
• /
• pp.451-458
• /
• 1990

고혈압 증세를 나타내는 정상체중과 비만의 SHR/Mcc-cp 숫쥐들에게 0.001% estrone 식이를 생후 6주부터 18주까지 투여하고, 매주 일회 24시간 금식 시키는 동안 뇨를 채취하여 뇨단백량을 측정하였다. Estrone 식이를 시작하기 직전에는 정상체중의 쥐와 비만의 주 모두에게서, estrone 식이군과 대조군 사이에 뇨단백량이 있어서, 유의한 차이가 없었다. 그러나, 정상체중의 쥐에게서, estrone 투여후 1주부터 estrone 식이군의 뇨단백량이 내조군에 비해 유의적으로 낮았다(p<0.05). 비만인 쥐도 estrone 식이후 1주부터 estrone 식이 군의 뇨단백량이 대조군에 비해 현저하게 낮아지기 시작해서 제 5주부터는 유의한 차이가 보였다. 그러므로, 0.001% estrone 식이가 성장기의 정상체중과 비만의 SHR/Mcc-cp 숫쥐들의 단백뇨 상태를 호전시킴을 발견했다. 또한, SHr/Mcc-cp 쥐들이 13주령 이전에는 정상체중의 쥐들이 비만인 쥐들보다, 더 높은 뇨단백량을 보였으나, 그이후부터 18주 사이의 주령에는 정상체중의 쥐와 비만의 쥐들 사이에는 유의적 차이가 없었다. 그러므로, SHR/Mcc-cp 쥐에게 있어서, 비만증 자체가 단백뇨 증세를 악화시키는 요인이 아님을 알 수 있었다.

• Journal of Preventive Medicine and Public Health
• /
• 제31권2호
• /
• pp.199-214
• /
• 1998

This study was undertaken to explain weight control behavior and intention of obese children and adolescents as measured by the elements of the health belief model. A total of 732 obese students from 28 schools in Seoul metropolitan area and their mothers were assessed with a self-administered questionnaire. The analyzed results are as follows; 1. Among obese students, 45.3% of male students and 57.2% of female students, a significantly higher portion than male students, reported that they had tried to lose weight within the recent year. Exercise was the most frequently used method to lose weight followed by diet control, drug use, and specialized clinic visits, in descending order. 2. Male students were more likely to try to lose weight if they perceived a low threat level and their mother had a job, and female students were more likely to try to lose weight if they were younger in age, perceived a low threat level and had strong external motivating factors. 3. Female students showed a significantly higher level of intention to obesity control than male students, and the intention level of their mothers also showed the same trend. 4. In male students, the degree of weight dissatisfaction, weight control experience, the level of obesity related beliefs of students, the educational level of the mother and economic status of the family were significant predictors of intention to obesity control, and in females, age, the level of obesity related beliefs of students and intention of their mothers were significant. In the mothers of male students, obesity index of students, age of the mother and the level of obesity related beliefs of the mother were significant predictors of intention of the mother, and in the mothers of female students, obesity index of students, occupational status of the mother and obesity related beliefs of the mother were significant. 5. According to the path model of intention to obesity control, the degree of weight dissatisfaction had the most powerful effect in male students, and perceived net benefit level was the most important variable in female students. Since the weight control behavior and intention of obese students were more predictable by the degree of weight dissatisfaction than the obesity index, we can conclude that only the students dissatisfied with their weight are well motivated for obesity control. There can be a discrepancy between the mother and her child's beliefs and intention status(especially in male students), so the therapists should also assess the student's opinion as well as the mother's. In female students, the perceived net benefit level wag the most important predictor of intention to obesity control, therefore the intervention program should pay particular attention to the positive benefits of weight control rather than negative aspects(threats) of obesity.

• 대한영양사협회학술지
• /
• 제12권1호
• /
• pp.55-67
• /
• 2006

The purpose of this study was to compare the food behavior and nutrient intakes, and the analysis of constituent parts of blood related to iron nutrition conditions and to investigate the correlation between iron nutrition conditions and obesity. Each subject was assigned to one of such as normal(n=55) and obese groups(n=60) according to their obesity index. Their nutritional status, serum iron status were evaluated based in 24-hr dietary recalls, questionnaire and blood analysis. The mean age of the normal group(10.76 years) and that of the obese group(10.95 years) made little difference. The height(p<0.05), weight(p<0.001), and obesity index(p<0.001) in the obese group were higher than those of the normal group in every respect. The 63.55% of the subject of this study gave an answer 'They eat breakfast daily', and the frequency of eating breakfast made little difference. The average intakes of energy were 1669.44 kcal(84.19% of EER) in the obese group and 1673.59 kcal(86.72% of EER) in the normal group respectively, which made little difference between two groups. The intake of nutrients such as calcium and folate was as insufficient as below 75% of RI. The heme iron intake of the obese group was low that of the normal group(p<0.05). Among the major 20 iron resources the iron intake through animal food intake were 1.43 mg(12.00%) in the obese group and 1.93 mg(17.72%) in the normal group respectively. The rating of iron condition in the blood showed that the number of red blood cell(p<0.01), the hemoglobin(p<0.001), and hematocrit(p<0.01) of the obese group were lower than those of the normal group. These results suggest that there should be the right choice of food according to its bioavailability and nutritive guidance to appropriate food behavior, in addition to increasing iron intake to improve iron nutrition conditions of obese male elementary school students.

• Journal of Nutrition and Health
• /
• 제21권5호
• /
• pp.283-294
• /
• 1988

To study the factors related to childhood obesity, 75 subjects were selected as an obese group and 75 subjects were selected as a control group according to their obesity index and BMI among the 583 children of 5th and 6th grade in elementary school in Seoul. For each subject, skinfold thickness was measured, information on the characteristics of family, nutrient intake and activity time of the subjects were obtained by questionnarie. The results were summarized as following: 1) Parents' obesity indices of obese group were significantly higher than those of control group(Father's Obesity Index : P<0.01, Mother's Obesity Index : P<0.05). 2) Questions about eating rate and behavior showed that subjects in obese group were significantly faster in their eating rate(p<0.05) and always more eager to eat food(p<0.001) compared to control group. 3) Dietary intake data showed that average daily intake of all the nutrients exceeded Korean recommended dietary allowances for the age group. In female children, fat intakes of obese group were significantly higher than control group(P<0.05). There was no such significant difference in male subjects. 4) Activity time record of subjects reveal that there was a trend for males to spend more time in moderate and high activity and less time in light activity compared to females. Subjects in obese group spent significantly more time for light activity(P<0.001) and significantly less time for moderate activity (P<0.001) compared to subjects in control group. The difference of activity was more pronounced in male subjects. 5) Correlation matrix of the variables showed that obesity index, BMI, and skinfold thickness of the subjects were highly correlated with each other. These indices were positively correlated to parent's obesity indices and the time spent for light activity, but negatively correlated to the time spent for moderate activity. Nutrient intakes were not significantly correlated to obesity indices. Form the results shown above, although both obese and control groups are from high socioeconomic class, obese children tended to come from family with fat parents. They eat fast and are always eager to eat. They tend to eat more fat but are very different from controls in nutrient intake. Obese children are significantly lower in their actinity compared to controls. So, for the prevention and treatment of childhood obesity, it seems to be more important to increase their activity levels.

• 한국식생활문화학회지
• /
• 제28권5호
• /
• pp.547-552
• /
• 2013

This study compared the nutrient intake of obese versus non-obese non-insulin dependent diabetes mellitus (NIDDM) patients for Diabetes Medical Nutrition Therapy. The study was conducted at medical hospitals in Gyeonggi and Seoul from April 2009 to November 2009. Fifty-six adult male NIDDM patients were enrolled and divided into two groups: 36 into an obese group (BMI ${\geq}25$) and 20 into a non-obese group (BMI<25). To conduct this study, anthropometric measurements, and daily nutrient intake of obese and non-obese NIDDM patients were measured. Daily nutrient intake was estimated by 24hr-recall and analyzed by the CAN program. In the results, anthropometric measurements of the two groups showed significant differences in weight and BMI (p<0.001). Daily nutrient intake of the two groups showed no significant differences, except for vitamin E intake (p<0.05). The total energy intake of the non-obese and obese groups were $2,669.9{\pm}964$ kcal and $2,555.4{\pm}803$ kcal, respectively, which were both above 113% of the recommended Dietary Reference Intakes for Korean (KDRIs). Cholesterol and sodium intake were $378.1{\pm}215.6$ mg and $6,478.9{\pm}2755.1$ mg, respectively for the non-obese group. Cholesterol and sodium intake were $308.1{\pm}155.6$ mg and $6,306.8{\pm}2788.9$ mg, respectively, for the obese group. Both groups were above 150% of the recommended levels set by the Korean Diabetes Association (KDA). However, their antioxidant nutrient intake was appropriate. Meanwhile, their fiber intake was $10.7{\pm}5.1$ g and $9.8{\pm}5.2$ g, respectively, which was lower than 40% of the recommended intake set by the KDA. The results show that the nutritional education for obese and non-obese NIDDM male patients must aim to reduce total energy, cholesterol, and sodium intake, while increasing fiber intake. In addition, the factors related to a patient's glycosylated hemoglobin, serum lipids, blood pressure, and weight change must be calibrated for the appropriate energy, fat, cholesterol, sodium, and dietary fiber intake.

• Journal of Nutrition and Health
• /
• 제38권6호
• /
• pp.445-454
• /
• 2005

The purpose of this study was to compare the validity of obese index among body mass index (BMI), waist to hip ratio (WHR), and waist circumference (WC) and to determine which is the best in relation to cardiovascular disease (CVD) risk in Korean elderly more than 65 ages. Data from the 1998 Korean Health and Nutrition Survey were used (n=1017). Anthropometric indices and CVD risk factors were measured, and chi-square test, analysis of variance following duncan's multiple range test, partial correlation analysis, and Receiver Operator Characteristic (ROC) curves were used in the analysis. Anthropometric values were decreased in both male and female when ages were goes up. In female elderly, it specially showed the characteristics of upper body fat and systolic blood pressure risk (p<0.05). Among life style factors the current smokers were prevalent in obese male (p<0.05), but not prevalent in female having obese or upper body fat. Also, person with upper body obesity have more exercise than that of normal group (p<0.01). Mean BMI values of the current smoker was lower than that of normal group in both sexes (p<0.01). Mean BMI value of person with other risk factors were higher than that of normal groups (p<0.05). Among 7 CVD risk factors in partial correlation analysis, WC had the highest correlation coefficient in 5 in male, whereas BMI in 4 in female. In ROC analyses of 12 risk factors and health conditions, the largest area under curve of obese indices for risk factors were WC>WHR>BMI in male and BMI>WHR>WC in female. The optimal cutoff values of each index (BMI : WHR : WC) for one or more risk factors were 19.02 : 0.84 : 71.3 in male and 19.04 : 0.88 : 85.6 in female. In conclusion, Most Korean elderly showed non-obese and abdominal obesity likewise other Asians. Also CVD risk factors were prevalent in Korean elderly within normal limits of obese indices. Therefore the upper body fat indices reflected in the aged whose muscle mass is replaced by fat must be used as an indicator of CVD risk together with BMI. Although WHR was the worst index based on partial correlation analysis and so located between BMI and WC in ROC curve analysis in both sexes, it need to be use with WC to screen the cardiovascular risk group.

• 지역사회간호학회지
• /
• 제12권3호
• /
• pp.732-745
• /
• 2001

This study attempted to identify obese students' stress and coping method in middle and high schools. The data were collected from the total of 600 obese students from middle and high schools in Pusan. The author used a convenience sampling method. The data collection was done from March 2 to April 30. 2001. The analysis of the data was done with SPSS Win(10.0) for descriptive statistics. t-test. and ANOVA. The instrument used for the obese students' stress and coping method was a questionnaire developed by Kim. Yi-Soon and Kim. Young-Hae(200l). The tool was composed of 65 items (33stress items: 32coping method items) with the five-point Likert scale. The results were as follow: 1. The average score of stress was 2.49 (SD = .86) points in the male students. and 2.83(SD= .86) points in the female students. The subcategories were: (outward appearance), (boyfriend/girlfriend), (occurrence of an outbreak of a disease), (relationship within the family), (an obese appearance), (difficulty in exercise). The highest degree of stress came from 'an obese appearance' for the male students (mean=2.64. SD=0.87) and (mean=2.64. SD=0.87) for the female students. 2. The subcategories of the coping method were: (be concerned about other matters), (recreation activities), (self-violence), (relaxation), (hobby activities), (avoid a situation), (communication), (music), (negative behavior), (positive thinking). The highest degree of coping method were (recreation activities) in the male students (mean=3.07. SD=0.86) and (music) in the female students (mean=3.47. SD=1.01). 3. The results comparing stress with demographic variables were significant for gender (t=7.010. p=0.000). grades at school (F=2.918. p=0.02l), degree of obesity (F=5.205. p=0.006). grades (F=2.550. p=0.027). standard of living(F=8.277. p=0.000). the state of health (F=2.882, p=0.022), relationship with the father (F=4.790, p=0.001), relationship with the mother (F=6.080, p=0.000), and the educational level of the father (F=3.192, p=0.013). 4. The results comparing the coping method with demographic variables were significant for gender (t=4.597. p=0.000). These findings contribute to the understanding of the degree of stress and the type of coping methods of obese students in middle and high schools. Therefore, the result of this study aids in an effective nursing intervention to improve the mental health program for the obese.