• Title/Summary/Keyword: obese factor

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A study on breast from classification of elderly womend (노년여성 흉부 체형유형화에 관한 연구(I))

  • 이경화
    • Journal of the Ergonomics Society of Korea
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    • v.13 no.2
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    • pp.25-31
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    • 1994
  • This research examines classifying and characterizing breast form's classification on elderly women, 242 subjects from 55 to 75 years of age participated. 27 direct anthropometric measurement were applied to classify the breast typesl. We analyzed measurement data using factor analysis, cluster analysis, analysis of variance. The results of the study were as follows. 1) 55-64 aged group was taller and higher than 65-79 aged group. Typical breast form in 55-64 aged group was more obese than breast form in 65-79 aged group. 2) We extracted 5 factors(obesity of breast, height of breast, height of breast items, location & size of breast, width of upper chest & shouldet length, height of breast & lower length of nipples) from total items through factor analysis. 3) Through cluster analysis, we categorized 3 clusters. Namely, type 1; characterized the best slender type, type 2; characterized middle sized type, type 3: characterized obesity type. Type 2 is the typical type on elderly women.

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Upper Body Type Analysis for Middle-aged Women Aged 50-69 Years (50-69세의 중장년 성인여성을 위한 상반신 체형분석)

  • Lee, Jin Hee;Kim, Eun Kyong
    • Journal of the Korea Fashion and Costume Design Association
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    • v.24 no.3
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    • pp.49-61
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    • 2022
  • This study aims to provide upper body shape information by analyzing the measurement data of middle-aged women aged 50-69, including baby boomers, whose economic power and activity have improved compared to the previous generations. In order to provide accurate upper body shape information by analyzing the body type using the 8th Size Korea measurement data, body shapes were classified through factor and cluster analysis using 75 direct measurement items. Upper body type was classified according to the factors, and the associated characteristics were analyzed. As a result of the comparative analysis of the upper body measurements from the 4th to the 8th Size Korea measurement, it was found that in the height item, both the waist height and the hip height increased, making the overall height greater and the leg length longer. The body circumference items tended to increase, but were found to decrease significantly in the 8th Size Korea (2021) measurement. Middle-aged women were classified using five factors. Factor 1 was the upper body obesity factor, and Factor 2 was the trunk vertical factor. Factor 3 was the width of the back shoulder, Factor 4 was the vertical factor behind the back, and Factor 5 was the length factor of the front garment composition. Middle-aged women were classified into four body types through cluster analysis. Type 1 is relatively small and skinny, Type 2 has the most obese upper body and developed back shoulders, and Type 3 is skinny and has a long back and short front. In Type 4, the upper body was relatively long and the shoulders were narrow.

Sasa borealis leaves extract improves insulin resistance by modulating inflammatory cytokine secretion in high fat diet-induced obese C57/BL6J mice

  • Yang, Jung-Hwa;Lim, Hyeon-Sook;Heo, Young-Ran
    • Nutrition Research and Practice
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    • v.4 no.2
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    • pp.99-105
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    • 2010
  • Obesity is considered a mild inflammatory state, and the secretion of inflammation-related cytokines rises as adipose tissue expands. Inflammatory cytokines, including tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interlukin 6 (IL-6) and monocyte-chemoattractant protein 1 (MCP-1), are modulated by adipose tissue and known to play an important role in insulin resistance which is the common characteristics of obesity related disorders. In this study we analyzed the effects of Sasa borealis leaves extract on inflammatory cytokines and insulin resistance in diet induced obese C57/BL6J mice. The obese state was induced by a high fat diet for 20 weeks and then the mice were divided into two groups; obese control group (OBC, n = 7) and experimental group (OB-SBE, n = 7). The OBC group was fed a high fat diet and the OB-SBE group was fed a high fat diet containing 5% Sasa borealis leaves extract (SBE) for 12 weeks. We also used mice fed a standard diet as a normal control (NC, n = 7). The body weight and adipose tissue weight in the OB group were significantly higher than those in the NC group. The effects of the high fat diet were reduced by SBE treatments, and the body weight and adipose tissue deposition in the OB-SBE group were significantly decreased compared to the OBC group. The OBC group showed higher serum glucose and insulin levels which resulted in a significant increase of incremental area under the curve (IAUC) and HOMA-IR than the NC group. Also, serum leptin, TNF-${\alpha}$, and IL-6 levels were significantly higher in the OBC group than in the NC group. In contrast, the OB-SBE group showed a reversal in the metabolic defects, including a decrease in glucose, insulin, IAUC, HOMA-IR, TNF-${\alpha}$, IL-6 and leptin levels. These results suggest that BSE can suppress increased weight gain and/or fat deposition induced by a high fat diet and theses effects are accompanied by modulation of the inflammatory cytokines, TNF-${\alpha}$ and IL-6 secretion resulting in improved insulin resistance.

Effects of Long-Term High-Fat Diet Feeding on Gene Expression of Inflammatory Cytokines in Mouse Adipose Tissue

  • Oh, Nu-Ri;Hwang, Ae-Rang;Jeong, Ja-In;Park, Sung-Hyun;Yang, Jin-Seok;Lee, Yong-Ho
    • Biomedical Science Letters
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    • v.18 no.1
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    • pp.56-62
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    • 2012
  • This study was to investigate the effects of high-fat diet feeding for a very long period of time on gene expression of inflammatory cytokines in mouse adipose tissue and to determine whether caloric restriction (CR) or insulin sensitizer treatment changes the cytokine gene expressions even in obese mice fed a high-fat diet for a very long term-period. Gene expression levels of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-6 (IL-6), and monocyte chemoattractant protein-1 (MCP-1) were examined by real-time PCR in subcutaneous abdominal adipose tissue (SubQ) from obese and non-obese male C57BL/6 mice at 16, 26, 36, 47, and 77 weeks of age on either normal diet (ND) or high-fat diet (HFD) after starting at 6 weeks of age. In addition, gene expression levels of TNF-${\alpha}$, IL-6 and MCP-1 were determined in SubQ before and after rosiglitazone treatment or CR on 47-week-old obese mice. The results demonstrated that gene expression levels of TNF-${\alpha}$, IL-6 and MCP-1 were significantly increased with aging in SubQ of mice in both groups of diet. MCP-1 gene expression of SubQ in all ages tested was significantly or marginally increased in mice on HFD compared with ND. While TNF-${\alpha}$ expression was significantly reduced by rosiglitazone, IL-6 and MCP-1 were significantly decreased by CR. The basic data in this study will be useful for characterizing the C57BL/6 mouse as an animal model of obesity induced by high-fat diet feeding for a very long period of time, and a better understanding of inflammatory cytokine regulation in diet induced obesity which may facilitate the development of new therapeutic strategies to prevent the complications of obesity.

Distribution and Correlates of Obesity School Children in a Region (일 지역 학령기 아동의 비만수준과 비만관련 요인)

  • Choi, Gil-Soon;Kwon, Hay-Rran
    • The Korean Journal of Emergency Medical Services
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    • v.12 no.1
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    • pp.53-67
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    • 2008
  • Purpose : This study is descriptive correlation research to provide basic materials for developing program which can give practical assistance in preventing and managing obesity through more comprehensive approaches of influential factors on obesity found in existing literatures. Methods : Data were collected from the 4th, 5th and 6th graders at 2 elementary schools in Gwangju Metropolitan City and 4 elementary schools in Jeollanamdo province using questionnaire and students' physical examination results from June 15 to July 27, 2006 and data obtained from 1,866 students were used for analysis. Data collected were analyzed with technical statistics and correlation analysis using SPSS/PC(version 12.0). Results : 1. Obesity level of elementary school students was examined as follows; 33.2% had low weight, 44.3% normal, 10.8% overweight and 11.7% obese. 14.8% of boys and 8.6% of girls, 13.5% of the 4th graders, 12.1% of the 5th graders and 9.2% of the 6th graders, and 13.7% of urban students and 9.6% of rural students were obese. 2. According to general characteristics and obesity of the subjects, there were significant differences by sex(${\chi}^2=29.55$, p= .000), grade(${\chi}^2=12.84$, p= .046), region(${\chi}^2=41.96$, p= .000) and pocket money(${\chi}^2=33.43$, p= .001). 3. As genetic factors, all variables including sibling's obesity r= .128(p= .000), mother's obesity r= .098(p= .000) and father's obesity r= .081(p= .001) had influence on children's obesity. 4. Concerning environmental factors, there was positive correlation between eating habits r=- .052(p= .02) and school record r=- .048(p= .04) and there was negative correlation between internet using time r= .050(p= .03) and conflict with parents r= .048(p= .04). 5. Self-respect as psychological factor had negative correlation as r=- .048(p= .04). Conclusion : Consequently, the influential factors on obesity of elementary school students were as follows. Obesity was higher in boys than in girls, in urban areas than in rural areas, in lower grade than in higher grade, in children with obese siblings, obese father and mother, irregular and wrong eating habits, frequent internet uses, parents in conflict and lower school record and self-respect. Therefore, since it was found that these variables were more exact causes to increase children's obesity, development of various obesity mediation programs considering these variables at home, school and society is urgently required.

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The Metabolic Syndrome in Obese Children (소아 비만에서 대사증후군의 고찰)

  • Yom, Hye Won;Shin, Jee Seon;Lee, Hyun Joo;Park, So Eun;Jo, Su Jin;Seo, Jeong Wan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.7 no.2
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    • pp.228-238
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    • 2004
  • Purpose: Obesity is rapidly increasing in Korean children. Obesity is a risk factor for cardiovascular morbidity and is frequently associated with hypertension, diabetes mellitus and coronary artery disease. This study was designed to evaluate risk factors of the metabolic syndrome in obese children. Methods: From February 2000 to June 2004, eighty eight obese (body mass index ${\geq}95th$ percentile) children aged 4 to 15 years were included. We measured serum lipid levels (total cholesterol, triglyceride, HDL cholesterol, LDL cholesterol), fasting sugar levels and insulin levels. Insulin resistance was determined by homeostasis model assessment, fasting insulin/glucose ratio and quantitative insulin sensitivity check index. Results: Clustering of risk factors for the metabolic syndrome in obese children demonstrated that 60.2% had more than one risk factors. Hypertension (14.8%), hypertriglyceridemia (14.8%), HDL-hypocholesterolemia (14.8%), LDL-hypercholesterolemia (12.5%) and hyperinsulinemia (12.5%) were observed. As BMI increased, there was statistically significant increase in systolic blood pressure, insulin and insulin resistance values. Insulin resistance was correlated to systolic blood pressure, serum lipid and insulin levels. The more risk factors for the metabolic syndrome obese children had, the higher was their insulin resistance. Conclusion: The increase in insulin resistance and clustering of risk factors for the metabolic syndrome are already apparent in obese children. Monitoring these risk factors for the metabolic syndrome should become a part of routine medical care for obese children.

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A Study of the Relationship between Childhood Obesity and Beverage Intake (소아비만과 음료 섭취량의 관계에 대한 연구)

  • Oh, Ji Hyun;Kwak, In Keun;Yang, Seung;Hwang, Il Tae;Jung, Ji Ah;Lee, Hae Ran
    • Clinical and Experimental Pediatrics
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    • v.46 no.11
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    • pp.1061-1066
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    • 2003
  • Purpose : The rising prevalence of childhood obesity may be due to an energy imbalance between food intake and energy expenditure. Recently, consumption of beverages in children has increased. The aim of this study is to provide useful information for the prevention and the control of childhood obesity by assessment of variable beverage consumption. Methods : Fight hundred seventy seven children(M : F=1 : 1.02, mean age; 9.7 years) from two primary schools in Seoul in May 2003 were enrolled. Body mass index(BMI) was calculated and the degree of obesity was classified into normal, overweight and obese groups by BMI percentile. Parental BMI, socio-economic factor, 3-day dietary intake, calory intake and beverage intake were examined by questionnaires. We researched beverages and classified them into six categories, milk, other milk products, soda, sports beverage, other beverage. Results : The prevalence of obesity was 7.2%. The parental BMI of the obese group were higher than those of the other groups. There was no significant difference in birth weight, or parents' intellectual and economic levels between the obese group and the other groups. There was no significant difference in daily total calory intake between the obese group and the other groups. The obese group of 7-9 year-old-males was higher than the other groups in sodas, and sports beverages intake. The obese group of 10-12 year-old-males was higher than the other groups in total beverage intake and other beverage intakes. The obese group of 10-12 year-old-females was higher than the other groups in other milk products. Conclusion : Excessive intake of beverages is associated with childhood obesity. Efforts to decrease intake of beverages may be important approaches to counter the rise in the prevalence of obesity.

The Role of Adipokines in the Pathogenesis of Non-alcoholic Fatty Liver Disease in Obese Children; the Relationship between Body Fat Distribution and Insulin Resistance (비만아의 비알코올성 지방간 발병에 있어 Adipokine과 체지방분포 및 인슐린 저항성과의 연관성에 대한 연구)

  • Yang, Hye-Ran;Ko, Jae-Sung;Seo, Jeong-Kee
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.10 no.2
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    • pp.185-192
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    • 2007
  • Purpose: This study was conducted to evaluate the role of adiponectin, leptin, and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) in obese children, and to elucidatethe relationship between these adipokines and insulin resistance. Methods: A total of 61 obese children (M : F=42 : 19, mean age 11.2${\pm}$1.3 years) admitted to our facility between March 2004 and June 2005 were included in this study. Patients were divided into three groups based on their NAFLD status obese children without fatty liver (N=23); obese children with simple steatosis (N=20); and obese children with non-alcoholic steatohepatitis (NASH) (N=18). The serum levels of adiponectin, leptin, and TNF-${\alpha}$ were measured, and insulin resistance determined by homeostasis model assessment (HOMA-IR) was calculated to estimate insulin resistance. In addition, the VSR (visceralsubcutaneous fat ratio) was estimated using abdominal computed tomography. Results: There was no difference in serum TNF-${\alpha}$ and leptin levels observed between the 3 groups (22.13${\pm}$6.37 vs. 21.35${\pm}$6.95 vs. 25.17${\pm}$9.30; p=0.342 & 20.29${\pm}$8.57 vs. 16.42${\pm}$6.85 vs. 20.10${\pm}$7.86; p=0.330). However, the serum adiponectin level was significantly lower in children with non-alcoholic steatohepatitis (NASH) than in the other two groups (6.08${\pm}$1.38 in children without steatosis vs. 5.69${\pm}$0.79 in simple steatosis vs. 4.93${\pm}$1.75 in NASH; p=0.026). In addition, the VSR was significantly increased in the NASH group (0.31${\pm}$0.08 vs. 0.32${\pm}$0.11 vs. 0.47${\pm}$0.14; p=0.001), and HOMA-IR revealed a significant difference among the three groups (4.77${\pm}$3.67 vs. 6.89${\pm}$7.05 vs. 10.42${\pm}$6.73; p=0.000). However, there was no significant correlation observed between the adiponectin levels and the HOMA-IR or the VSR (r=-0.117; p=0.450 & r=-0.106; p=0.499). Conclusion: Insulin resistance may affect the development of hepatic steatosis and steatohepatitis in children, and the results of this study suggest that, of several adipokines evaluated, adiponectin is important in the progression of steatosis to steatohepatitis in obese children.

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HIF-1α-Dependent Induction of Carboxypeptidase A4 and Carboxypeptidase E in Hypoxic Human Adipose-Derived Stem Cells

  • Moon, Yunwon;Moon, Ramhee;Roh, Hyunsoo;Chang, Soojeong;Lee, Seongyeol;Park, Hyunsung
    • Molecules and Cells
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    • v.43 no.11
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    • pp.945-952
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    • 2020
  • Hypoxia induces the expression of several genes through the activation of a master transcription factor, hypoxia-inducible factor (HIF)-1α. This study shows that hypoxia strongly induced the expression of two carboxypeptidases (CP), CPA4 and CPE, in an HIF-1α-dependent manner. The hypoxic induction of CPA4 and CPE gene was accompanied by the recruitment of HIF-1α and upregulation in the active histone modification, H3K4me3, at their promoter regions. The hypoxic responsiveness of CPA4 and CPE genes was observed in human adipocytes, human adipose-derived stem cells, and human primary fibroblasts but not mouse primary adipocyte progenitor cells. CPA4 and CPE have been identified as secreted exopeptidases that degrade and process other secreted proteins and matrix proteins. This finding suggests that hypoxia changes the microenvironment of the obese hypoxic adipose tissue by inducing the expression of not only adipokines but also peptidases such as CPA4 and CPE.

Study of Real Somatotype and Perceived Body Classified by Body Index of College Women (여대생(女大生)들의 지수치(指數値)에 의한 체형(體型) 집단(集團)별 실제체형(實際體型)과 신체인식(身體認識)에 관한 연구(硏究))

  • Lee, Jung-Soon
    • Journal of Fashion Business
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    • v.11 no.5
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    • pp.100-109
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    • 2007
  • The purpose of this research is to study the recognition of real somatotype and body of college women. The study was carried out by classifying somatotypes into three categories based on the body index; slim, normal, and obese somatotype. The subject of this study was 106 college women, and real measurement and survey were used. Data was analyzed by SPSS 12.0 and cross tabulation analysis, t-test, Anova, and correlation analysis were operated. The result is as follows. 1. The height of the subjects was 163.5cm, weight was 53.3kg, Rohrer index was 1.2, BMI was 19.9, Vervaeck index was 84.4 and the classification based on the body index belonged to the normal group. 2. The characteristics of groups divided by the body index are that slimmer groups is longer in length factor and smaller in the factors related with volume than other groups. The characteristics of groups classified by self-consciousness shows significant difference in all girth factors, back intersyce breadth, front intersyce breadth, neck to nipple length, and nipple to nipple breadth. 3. Conscious about the somatotype with using body index generally shows similarity. In the length factor including height, slim somatotype group is perceived as longer than normal somatotype group, and in the girth factor including weight, normal somatotype group is recognized as bigger and thicker than others.