• The Korean Journal of Community Living Science
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• v.24 no.1
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• pp.141-149
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• 2013

The objective of this study is to find the effect of improving hyperlipidemia through Platycodi radix saponin. A hypercholoesterol diet and Platycodi radix saponin methanol extract were supplemented to the 6 week old male Spargue Dawley rats for four weeks. Results showed that the serum total cholesterol, triglyceride and LDL-cholesterol level decreased in the group supplemented with Platycodi radix saponin methanol extract(p<0.05), however, the serum total lipid and HDL-cholesterol did not show any difference from the control group according to the supplement of Platycodi radix saponin methanol extract. In the group supplemented with Platycodi radix saponin methanol extract, the total cholesterol decreased by 20%, triglyceride by 36% and LDL-cholesterol by 25% respectively, and there was no difference according to the level of Platycodi radix saponin methanol extract. AI(atherogenic index) and CRF(cardiac risk factor) were low in the group supplemented with Platycodi radix saponin methanol extract. Total lipid, total cholesterol and triglyceride in liver and feces were significantly low in the group supplemented with the Platycodi radix saponin methanol extract compared with the control group(p<0.05). According to this result, it is expected that the Platycodi radix saponin methanol extract supplemented in the hypercholesterol diet can lower atherosclerosis, the cause of cardiovascular disease, by reducing not only serum cholesterol and triglyceride but also liver cholesterol and triglyceride.

• Journal of Korean society of Dental Hygiene
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• v.15 no.3
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• pp.399-410
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• 2015

Objectives: The purpose of the study is to investigate the influencing factors of metabolic syndrome on the periodontal disease in the Korean adults over 40 years old. Methods: The data were extracted from the Fifth National Health Nutrition Survey 2010. The subjects were adults over 40 years old. The periodontal diseases were examined by direct survey. The questionnaire consisted of the general characteristics of the subjects, oral health behavior, metabolic syndrome, and relation to periodontal diseases. CPI(community periodontal index) was measured. CPI indicates periodontal condition and classified into alveolar arch of the upper jaw and the lower jaw. A periodontal disease is defined as $CPI{\geq}3$(over 4 mm). The variables for metabolic diseases included hypertension, diabetes mellitus, dyslipidemia, and obesity measured as BMI. Results: Diabetes mellitus is closely related to periodontal diseases prevalence. Low level of HDL increase the periodontal diseases. Number of toothbrushung, use of dental floss and interdental toothbrush as for the number of toothbrushing, more than twice toothbrushing a day, and use of dental floss and interdental toothbrush reduced periodontal diseases. Conclusions: The risk factors of periodontal disease in Korean adults over 40 years old were sex, age, residence, monthly income, education level, smoking, diabetes and low HDL cholesterol.

• Journal of Korean Public Health Nursing
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• v.31 no.3
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• pp.451-463
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• 2017

Purpose: The purpose of this study is to investigate the drinking, stress, and sleep on depression of Korean obese women. Methods: The data of this study were derived from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VI-3), conducted from January to December 2015 by Korea Centers for Disease Control and Prevention. The study subjects were 935 adult women between 20 and 70 years old (Body Mass Index${\geq}25$). The data were analyzed by the complex sampling design method applying the weights to the IBM SPSS 23.0 program. Results: The study result showed that the frequency of binge drinking, stress perception, sleeping time and depression of Korean obese women showed significant differences according to age group. In the 20-30's, the stress and sleeping time, the 40-50's were drinking at once, the frequency of drinking and stress, and the drinking and stress at 60-70's were significantly associated with an increased risk of depression in obese women. Conclusion: The intervention program for the management of depression in Korean obese women should include the strategies for managing stress and drinking, taking into account differences according to age.

• Asian-Australasian Journal of Animal Sciences
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• v.14 no.4
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• pp.535-539
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• 2001

The present study was conducted to evaluate the effect of fermented chub mackerel extract (FCME) on lipid metabolism in rats fed diets without cholesterol. Four week-old male rats were divided into three groups of 10 rats with 0, 1% or 2% FCME supplementation to the diets. Purified diets were used in the present study. Feed and water were fed ad libitum. FCME supplementation had no effect on the activities of acetyl-CoA carboxylase, fatty acid synthetase, and the content of free cholesterol, triglyceride and phospholipid in the liver (p>0.05). 1% FCME supplementation significantly increased serum triglyceride (p<0.05) and hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity (p<0.05) with no effect on serum total cholesterol, free cholesterol and phospholipid concentration. FCME supplementation significantly reduced serum LDL+VLDL-cholesterol (p<0.01) and atherogenic index (p<0.01) with no effect on HDL-cholesterol. The current study showed that FCME inclusion might reduce the risk of atherosclerosis in rats fed diet without cholesterol.

• Journal of Korean society of Dental Hygiene
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• v.16 no.6
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• pp.825-833
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• 2016

Objectives: The purpose of the study was to examine the relationship between smoking behavior and periodontitis in Korean adults. Methods: The study subjects were 4,896 from the sixth Korean National Health and Nutrition Examination Survey. Data were analysed by chi-square test and multiple logistic regression analysis using SPSS 20.0 program. Results: The rate of periodontitis was 27.5%. The prevalence rate of periodontitis was closely related to socio-economic characteristics including gender, age, living area, household income, educational level, history of diabetes mellitus, and regular dental visit. The rate of periodontitis in non-smoker, ex-smoker, and current smoker were 56.7%, 19.5%, and 23.8%, respectively. Smoking behavior was significantly related to socio-economic characteristics. After adjusting for gender, age, household income, educational level, history of diabetes mellitus, and dental visit within 1 year, the risk of periodontitis in ex-smoker and current group were 1.31 (95% CI; 1.04-1.65) and 2.31 (95% CI; 1.87-2.85), respectively. Conclusions: Smoking behavior had a significant impact on periodontitis prevalence in Korean adults.

• Journal of Korean society of Dental Hygiene
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• v.20 no.4
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• pp.421-433
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• 2020

Objectives: The aim of this study was to examine the relationship between periodontitis, obesity, and health behavior according to sex and age in Korean adults. Methods: Data on 11,032 adults aged 19-79 years were obtained from the 7th Korea National Health and Nutrition Examination Survey (KNHNES). We used multivariate logistic regression analysis to test for associations. Results: The final model that was adjusted for demographic characteristics and health status, showed a higher risk of periodontitis with increasing body mass index (BMI), smoking, failure to use oral care products, and no dental check up. In the sub-group analysis, only smoking was significant in the 19 to 39-year-old age groups. In the 40 to 64-year-old age group, a BMI of 30 or higher, and smoking, use of oral care products, and dental check-up were significantly associated with periodontitis. In the female group, BMI, smoking, use of oral care products, and dental check-up were significantly related to periodontitis. However, in males, only smoking was significant. Conclusions: Obesity management can be helpful for periodontal health as periodontitis prevalence in adults increased as BMI increased. For periodontal health, an oral health program should include smoking cessation and the use of oral care products and dental check up as part of obesity management.

• Journal of the Korean Dietetic Association
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• v.5 no.2
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• pp.145-152
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• 1999

This study was to investigate the risk factors for the development of diabetes mellitus on healthy offsprings of Korea non-insulin dependent diabetes mellitus(NIDDM) patients. Forty four offsprings who have at least 1 parent with NIDDM and age, sex and body mass index(BMI) matched forty four healthy control subjects were collected for this study. BMI, skinfold thickness, waist/hip circumference ratio(WHR), fasting blood glucose, serum insulin, serum lipid profile, nutrient intakes and food behaviors were measured. There were no significant difference in BMI, WHR, fasting blood glucose, insulin, total cholesterol, triglyceride and daily nutrients intake between offsprings and controls. But skinfold thickness, LDL-cholesterol level and sweety food eating frequency were significantly higher in male offsprings than in male controls. And HDL-cholesterol was significantly lower in male offsprings than in male controls. Although there were no significant difference, offsprings had a overeating habit and ate more confectionery and greasy food than controls.

• Journal of Preventive Medicine and Public Health
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• v.56 no.4
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• pp.338-347
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• 2023

Objectives: Young children's feeding characteristics can play an important role in eating habits and health during later childhood. This study was conducted to examine the associations of feeding characteristics with dietary patterns and obesity in children. Methods: This study utilized data from the Korea National Health and Nutrition Examination Survey conducted between 2013 and 2017. In total, 802 toddlers were included, with information on their demographic characteristics, feeding practices and duration, and 24-hour recall obtained from their parents. Feeding characteristics were categorized into feeding type, duration of total breastfeeding, duration of total formula feeding, duration of exclusive breastfeeding, and age when starting formula feeding. Dietary patterns were identified based on factor loadings for the food groups for 3 major factors, with "vegetables & traditional," "fish & carbohydrates," and "sweet & fat" patterns. Overweight/obesity was defined as ≥85th percentile in body mass index based on the 2017 Korean National Growth charts for children and adolescents. Multiple regression analysis was conducted to examine associations between feeding characteristics and dietary patterns. The association between dietary patterns and obesity was analyzed using multivariable logistic regression analysis. Results: The early introduction of formula feeding was inversely associated with the "vegetables & traditional" pattern (β=-0.18; 95% confidence interval [CI], -0.34 to -0.02). A higher "vegetables & traditional" intake was associated with a lower risk of obesity (odds ratio, 0.48; 95% CI, 0.24 to 0.95). Conclusions: Feeding characteristics are associated with dietary patterns in later childhood, and dietary patterns were shown to have a potential protective association against obesity.

• Journal of Yeungnam Medical Science
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• v.41 no.3
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• pp.141-149
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• 2024

Pediatric obesity has rapidly increased globally over the past few decades, including in Korea. We aimed to discuss trends in the prevalence of pediatric obesity and effective prevention strategies. Its prevalence has markedly increased in most high-income nations. According to recent reports, this increase has slowed in developed countries, but the levels remain alarmingly high. In Korea, the rate of pediatric obesity has surged notably since the 1990s; however, since the 2000s, this increase has become more gradual. According to recently published 2017 growth charts, the prevalence of pediatric obesity in Korea varies slightly depending on the data source. The National School Health Examination data showed that pediatric obesity gradually increase from 11.5% in 2014 to 15.1% in 2019, and after the coronavirus disease 2019 pandemic, it sharply increased to 19% in 2021. Based on data from the Korea National Health and Nutrition Examination Survey, the prevalence of pediatric obesity gradually increased from 10.8% in 2017 to 13.6% in 2019. This trend, which accelerated sharply to 15.9% in 2020 and 19.3% in 2021, was especially severe in boys and older children. Pediatric obesity not only affects health during childhood but also increases the risk of developing obesity and associated health conditions in adulthood. Despite ongoing research on treatment options, obesity prevention and control remain challenging. Hence, prioritizing early intervention and prevention of pediatric obesity through healthy eating habits and lifestyles is crucial. This requires intervention at the individual, family, school, and community levels.

• Journal of Preventive Medicine and Public Health
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• v.57 no.5
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• pp.421-434
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• 2024

Objectives: Schizophrenia is an organic disease and a severe mental disorder with a relatively high risk of relapse. The rising rate of schizophrenia relapse has motivated researchers and academics to innovate and develop interventions aimed at relapse prevention. This bibliometric study sought to examine the publication trends in schizophrenia relapse prevention from 1973 to 2023, assess the contribution of international collaborations across various journals, identify the most influential authors and articles, and forecast future developments in this field. Methods: The study included 683 articles obtained from the Scopus database, analyzed using VOSviewer software, and visualized with Tableau. Results: Reports of schizophrenia relapse prevention strategies have increased significantly over the last 3 decades. However, fluctuations persist, as evidenced by the annual number of publications ranging from 25 to 40 within the past 5 years. Nevertheless, this increasing trend underscores the sustained interest in this area of research. Regarding contribution size, the United States produced the largest volume of publications on this subject. John M. Kane authored the most articles, while Stefan Leucht exhibited the highest h-index. Frequently used keywords in this field include "relapse AND schizophrenia" AND "prevention." Conclusions: These results represent an important reference for determining the current state of research on schizophrenia relapse prevention and future research directions.