• 생명과학회지
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• 제23권9호
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• pp.1177-1182
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• 2013

선모충(Trichinella spiralis)은 감염 후 nurse cell 형성과정에서 영양분 공급 및 배설을 위해 혈관신생인자인 vascular endothelial cell growth factor (VEGF)를 유도하여 혈관신생을 촉진한다. 하지만 이러한 과정 중 선모충이 어떻게 VEGF의 발현을 유도하는지에 대해서는 아직 밝혀지지 않았다. Nurse cell 형성 과정에서 저산소현상이 발생되고 이러한 저산소 현상이 VEGF의 발현을 유도할 것이라는 제안이 있지만 실제 nurse cell 형성 과정에 저산호 현상이 일어나는지도 조사되지 않았으며 저산소 현상이 실제 VEGF를 통한 혈관신생을 유도하는지도 규명되지 않았다. 최근 연구결과에 의하면 VEGF의 발현을 유도하는 티모신베타4 단백질이 초기의 선모충 감염 nurse cell에서 강력하게 유도되는 것이 관찰되었다. 게다가 저산소 현상이 nurse cell 형성 과정에서 관찰되지 않았고 면역세포들이 응집되어 있는 파괴되는 nurse cell에서만 관찰되는 것이 밝혀졌다. 이러한 결과는 티모신베타4가 저산소 현상과 무관하게 선모충 감염 nurse cell에서의 VEGF 유도 및 혈관신생을 유도할 가능성을 제시해 준다.

• Applied Microscopy
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• 제25권4호
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• pp.17-25
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• 1995

This paper aims to probe the cell differentiation and gene activity in early Oogenesis from Dendrolimus spectabilis Butler by transmission electron microscope. The 8 cystocytes are formed by mitosis of the Oogonia, and differentiated to the 1 Oocyte and 7 nurse cells. The oocyte and nurse cells are connected by ring canals, through which the cytoplasmic organelles such as mitochondria, free ribosomes, and electron dense granular materials are passed from nurse cells to o cyte. Many replication fork in the cystocyte nuclei and 2 transcriptional units of $2.7{\mu}m\;and\;0.36{\mu}m\;or\;0.5{\mu}m$ in the nurse cells are observed by the chromatin spreading technique. It is possible that transcriptional units are passed from nurse cells to Oocyte.

• 디지털융복합연구
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• 제16권3호
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• pp.363-373
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• 2018

본 연구는 조혈모세포이식병동 간호사의 자율성과 직무만족도를 파악하고, 자율성과 직무만족도와의 상관관계를 규명하기 위한 조사연구이다. 국내 7개의 대학병원에 근무하는 간호사 79명을 대상으로 2013년 5월 20일부터 6월 4일까지 설문조사를 실시하였다. 분석방법은 SPSS 14.0을 이용하여 t-test, ANOVA, Pearson correlation coefficient를 실시하였다. 자율성 평균은 $165.47{\pm}19.56$점, 직무만족도 평균은 $3.15{\pm}0.35$점으로 나타났다. 자율성과 직무만족도는 상관관계를 보이지 않았으나, 직무만족도의 하부영역 중 자율성영역(r=.273)과 상호작용영역(r=.257)은 자율성과 유의한 정적 상관관계를 보였다. 이에 조혈모세포이식병동 간호사의 직무만족도 향상을 위해서 직무만족도의 하부영역인 자율성을 높일 필요가 있을 것이다. 따라서 본 연구결과는 조혈모세포이식병동 간호사들의 자율성과 직무만족도를 증가시킬 수 있는 교육과 정책프로그램을 개발에 유용한 기초자료로 이용될 수 있다.

• 종양간호연구
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• 제6권1호
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• pp.37-46
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• 2006

Purpose: The purpose of this study was to identify the influencing factors on anxiety of patients who had received hemopoietic stem cell transplantation(HSCT). Method: A total of 81 patients who had undergone a HSCT at a university hospital were recruited from July of 2001 to June of 2002. They were asked to complete questionnaires about anxiety, self-esteem, family support, doctor's support and nurse's support. Result: The mean score of anxiety, self-esteem, family support, doctor's support and nurse's support was 41.9, 3.0, 4.6, 7.6 and 7.3, respectively. A significant negative correlation was found between anxiety and self-esteem. Self-esteem was positively correlated with family support, doctor's support and nurse's support. The major variable that influenced anxiety was the self-esteem, explaining 25.4% of the anxiety. Conclusion: On the basis of these results, it is necessary for HSCT patients to develop a nursing intervention for the enhancement of self esteem. Also, family support, doctor's support and nurse's support should be considered as a main support system in the nursing strategy for improving the quality of life of patients undergone HSCT.

• 종양간호연구
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• 제5권2호
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• pp.116-125
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• 2005

Purpose: The purpose of the present study was variables in patients hemopoietic stem cell transplantation(HSCT) for leukemia. Method: A total of 88 participants were recruited at St. Mary's Hospital. The data were gathered from July, 2001 to June, 2002 using questionnaires. Result: The mean score of hope was $3.39{\pm}0.35$. Positive relationships were found between hope and self-esteem, physician's support, nurse's support, and satisfaction of life. And negative relationships were found between hope and depression, trait-anxiety, and state-anxiety. The major variable, that associated with hope, was the state-anxiety, explained 35.4% in the variance of the hope. Conclusion: Leukemic patients undergoing HSCT tended to have a high level of hope. Higher levels of self-esteem, physician's support, nurse's support and satisfaction of life were related with higher level of hope. And, higher the levels of depression and anxiety were related with a lower level of hope.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2008년도 춘계학술대회
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• pp.125-125
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• 2008

• Applied Microscopy
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• 제15권1호
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• pp.86-100
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• 1985

A observation of the ovarian development and oogenesis of Pieris rapae Linne has been carried out during metamorphosis using stereo-microscope, light microscope and electron microscope. The results obtained through this experiment are as follows: 1. The ovarian development and vitellogenesis begin at the 3-day old pupa and the 6-day old pupa respectively, and the adult ovary right after their emergence contains a few mature eggs. 2. The species described above are further observed at six different stages in oogenesis, and the results are summarized as follows. 1) Pieris rapae has polytrophic ovarioles. The cell organelles of the nurse cells are transfered to the oocyte through the ring canal at the early oogenesis. 2) At stage 2, the nuclear envelope of oocyte nucleus is less infolding than that of nurse cell nucleus. In the oocyte cytoplasm a large number of ribosomes are observed. 3) At stage 3 and 4, many micropinocytotic vesicles are observed in the oocyte cytoplasm. These vesicles are fused together to form large proteid yolks. 4) At stage 5, the vitelline membrane is laid down in the intercellular space between the follicle cells and oocyte. 5) At stage 6, the chorion is formed by the follicle cells. 6) A micropyle and a number of aeropyle are observed on the surface of a mature egg.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2005년도 ICCAS
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• pp.1409-1412
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• 2005

Therefore this study focused on developing real-time system, which makes it possible for nurses to check the residual quantity and changing time of Ringer's solution in nurses' room. Load Cell is utilized as a sensor to check the residual quantity of Ringer's solution. This Load Cell detects the physical changes of Ringer's solution and transfers electronic signal to the amplifier. Amplified analog signal is converted into digital signal by A/D converter. Developed Embedded system, which computes these data with microprocess(8052) then makes it possible to monitor the residual quantity of Ringer's solution real-time on a server computer. A Checking system on Residual Quantity of Ringer's Solution Using Load cell cut costs using a simple design for a circuit

• 한국임상수의학회지
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• 제24권2호
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• pp.172-176
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• 2007

The objective of this study was to determine the relationship between udder and teat characteristics and somatic cell count (SCC). A total of 749 (73.1%) milk samples from 1,024 quarters of 259 Holstein cows contained less than 200,000 somatic cells/ml, while 132 (12.9%) quarters contained more than 500,000 somatic cells/ml. Prior to data analysis, somatic cell counts were transformed to natural logarithm. The mean SCS {$log_e(SCS/10^3)$} of milk samples from the front quarters was lower than milk samples from the rear quarters. The highest SCS was observed from cows with the step-shaped udder and the pear-shaped teats, respectively. Increased SCS was observed from cows with large teat diameter, short teat length, short distance between the teat tip to floor (p<0.05) and with increase in parity, respectively.

• 한국동물학회지
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• 제38권4호
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• pp.505-513
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• 1995

P-lement의 germ line transformation을 이용하여 초파리 난소에서의 세포특이적 유전자발현 양상을 조사하였다. 표지유전자인 lacZ의 발현양상은 생식세포, 체세포, 두 종류의 세포에서 모두 발현되는 경우로 대별되며, 생식세포에서 lacZ의 발현은 조세포 또는 조세포와 난자에서 동시적으로 발현되는 경우로 구분되었다. 난자주변 난포세포에서의 lacZ 발현은 난자형성 9-10기 난포의 경우 모든 세포에서 균일하게 발현되거나 일부 세포에서만 발현되는 양상으로 구분되었다. 일부의 난포세포에서 발현되는 경우 난자와 조세포 경계의 난포세포에서 발현되는 경우, 이들을 제외한 난포세포에서 발현되는 경우로 구분되었다. 난자주위의 난포세포에서 난자의 전후축을 따른 구배현상도 관찰되었다. 극세포 또는 경계세포에서 발현되는 3개의 독립라인을 분리하였다. 독립된 EDL의 난소에서 나타난 lacZ의 발현양상은 초파리 난자형성에 관여하는 유전자의 시간과 공간적인 발현을 반영하며 이들 유전자 분리의 기초를 제공할 것으로 사료된다.