• The Journal of Korean Physical Therapy
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• v.12 no.1
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• pp.33-40
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• 2000

This study was carried out to compare the relation between vestibular function and balance skills in normal with heating-impaired children. The subjects were 20 normal children (8-10 years) and 20 hearing-impaired children (8-10 years). The SCPNT was used to assess vestibular function, then, functional reach test and backward walking test were usee to compare dynamic balance skills of normal and hearing-impaired children according to existence of visual input. The results were as follows : 1. In SCPNT, normal and hearing-impaired children showed statistical significance in all left-sided and right-sided rotations(p<.01), and the vestibular function responses of healing-impaired children were normal $20\%$, abnormal $45\%$, absent $35\%$. 2, To compare dynamic balance skills between normal and healing-impaired according to eye open and eye close, functional reach test did not show statistical significance in eye open situation(p>.05), but showed statistical significance in eye close situation(p<.05). 3. Backward walking test showed statistical significance in eye open and eye close situation(p<.01).

• Annals of Clinical Neurophysiology
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• v.19 no.1
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• pp.20-27
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• 2017

Background: We evaluated whether eye movements could reflect the efficacy of antiepileptic drugs in patients with epilepsy. Methods: Thirty patients with epilepsy of unknown cause as well as age- and sex-matched normal controls were enrolled in this study. We divided the patients into drug-controlled epilepsy (n = 22) and drug-resistant epilepsy (n = 8) groups according to their seizure controls. We analyzed the differences in the parameters of the eye movements in these two groups compared with normal controls using video-based electro-oculography. In addition, we investigated the differences in the cerebellar volumes of these two groups using whole-brain T1-weighted images. Results: The latency and accuracy of saccade in patients with epilepsy were significantly different from normal controls, but they were not different between patients with drug-controlled epilepsy and drug-resistant epilepsy. However, the gain of pursuit was significantly decreased in patients with drug-resistant epilepsy compared with normal controls (p = 0.0010), whereas it was not different between patients with drug-controlled epilepsy and normal controls (p = 0.9646). In addition, the patients with drug-resistant epilepsy had lower cerebellar volumes than normal controls (p = 0.0052), whereas the cerebellar volumes in patients with drug-controlled epilepsy were not different from normal controls (p = 0.5050). Conclusions: We demonstrated that pursuit eye movements could reflect the efficacy of antiepileptic drugs in patients with epilepsy, a finding that may be related to cerebellar dysfunction.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.1
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• pp.15-20
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• 2008

Purpose: To study on the confidence of dry eye diagnosis methods which need to prescribe contact lens. Methods: Non-invasive tear film break-up time (NIBUT) and tear film break-up time (TBUT) were measured in forty healthy subjects in their 20s, and then the subjects were classified into normal eye and dry eye. The results of McMonnies questionnaire, tear prism height measurement, Hardtack test, blink rate measurement and Schirmer test were compared with the results of NIBUT and TBUT. Results: The results of NIBUT and TBUT were as follows; 20 subjects had normal eyes, 10 subjects had dry eyes in both NIBUT and TBUT, and 10 subjects showed different results. In McMonnies questionnaire, the score of normal eye group averaged 8.2 and that of dry eye group averaged 18.5, which showed statistically significant difference. Furthermore, 100% of normal eye group classified by the results of NIBUT and TBUT corresponded with the result of McMonnies questionnaire and 90% of dry eye group showed the correspondence. Tear prism height of normal eye group averaged 0.32 mm and that of dry eye group averaged 0.23 mm, which were significantly different. Hardtack test, blink rate measurement and Schirmer test without local anesthesia showed no statistically significant difference between normal eye group and dry eye group. Conclusions: On dry eye diagnosis methods, the results of McMonnies questionnaire and tear prism height measurement had close correlation with the results of NIBUT and TBUT.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.17 no.2
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• pp.11-17
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• 2011

Background: To evaluate the influences of Eye movement program applied to elderly people on static balance. Methods: The subjects consisted of fourteen elderly people. The subjects were divided into two group. The control group (n=7) received no exercise and/or stimulation. The Eye movement program training (E/P) group (n=7) performed balance training using word card and batom. E/P group were accomplished during 4weeks (5 day/week, 60 min/day). All tests were completed before and after experiment. The static balance ability was measured by normal standing when eye open and close on good balance system, respectively. For each case, the experimental data were obtained in 3 item; mean X speed, mean Y speed and velocity moment. Results: The result of this study were as follows: 1. In E/P group, the statistically significants were shown on only mean Y speed in the case of normal standing when eye open (p<.05), but the statistically significants were not shown on mean X, Y speed and velocity moment in the case of normal standing when eye close (p>.05). 2. In control group, the statistically significants were not shown on all posture (p>.05). 3. There was a statistically significant difference on the mean Y speed and velocity moment in the case of normal standing when eye open between control group and E/P group (p<.05). Conclusions: The above results revealed that balance training using Eye movement program were partly effective for improving the static balance ability.

• The Journal of Korean Physical Therapy
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• v.11 no.2
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• pp.29-36
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• 1999

This study was carried out to compare the rotation between vestibular function and balance skills in normal and hearing-impaired children. The subjects were 20 normal children (8-10 years) and 20 bearing-impaired children (8-10 years). The SCPNT was used to assess vestibular function, then, one leg stance test was used to compare static balance skill of normal and hearing-impaired children according to existence of visual input and sex. The results were as follows: 1. In SCPNT, normal md hearing-impaired children showed statistical significance in all left-sided and right-sided rotations(p<.01), and the vestibular function responses of hearing-impaired children wore normal $20\%$, abnormal $45\%$, absent $35\%$. 2. To compare balance skills between normal and hearing-impaired according to eye open and eye close, one-leg stance Oat showed statistical significance in eye open(p<.05), but did not show statistical significance in eye close(p>.05). 3. SCPNT, ene-leg stance test did not show statistical significance according to sex(p>.05).

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.247-253
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• 2015

Purpose: The purpose of this study was to compare and analyze the ocular surface and the palpebral conjunctiva of categorized subjects, which were divided into normal eye group and dry eye group, by using a thermal camera. Methods: Subjects were 144 eyes of 72 normal university students, who didn't have any corneal disease, abnormal lacrimal ducts, medical records regarding ocular surgeries, or experience of using contact lens. Subjects were divided into two groups, which were normal eye group and dry eye group, based on the results of TBUT, Schirmer I test, and McMonnies test. After categorizing the subjects, the temperature of the subjects' ocular surface and the palpebral conjunctiva were measured and analyzed by using a thermal camera (Cox CX series, Answer co., Korea). Results: In the normal eye group's Central Ar.1, Nasal Ar.2, Temporal Ar.3, Superior Ar.4, Inferior Ar.5, the measured amount of temperature change on each area was $-0.13{\pm}0.08$, $-0.14{\pm}0.08$, $-0.12{\pm}0.08$, $-0.14{\pm}0.08$, $-0.10{\pm}0.09(^{\circ}C/sec)$. The dry eye group's results were $-0.17{\pm}0.08$, $-0.16{\pm}0.07$, $-0.16{\pm}0.08$, $-0.17{\pm}0.09$, $-0.15{\pm}0.08(^{\circ}C/sec)$. When compared with the normal eye group, the values of Ar.1, Ar.3, Ar.5 were significantly different in the dry eye group(p<0.05). The amount of temperature change, which was observed on the palpebral conjunctiva(Ar.1:central, Ar.2: nasal, Ar.3: temporal) of the normal eyes, measured by thermography, was $34.36{\pm}1.12$, $34.17{\pm}1.10$, $34.07{\pm}1.12^{\circ}C$ on each area. Same values taken from the dry eye group was $33.55{\pm}0.94$, $33.43{\pm}0.97$, $33.51{\pm}1.06^{\circ}C$ on each area. The values of Ar.1, taken from the dry eye group, had a significant difference, compared to the values of the normal eye group(p=0.05). Conclusion: The temperature of the ocular surface decreased faster on the dry eyes, compared to the normal eyes. The temperature measured on the palpebral conjunctiva of the dry eyes were also lower than the normal eyes. The temperature changes on the ocular surface, observed with a thermal camera, were objective values to assess the stability of tear films, and might provide useful data for studies related to dry eye syndrome.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.203-209
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• 1999

A 4-year-old female Shih-tzu with severe episcleral congestion and buphthalmos in left eye was referred to the Veterinary Teaching Hospital, Chonnam National University in October 1998. During two months in local veterinary clinics, the dog had been treated unsuccessfully with tarsorrhaphy and antibiotics. By history taking, cause of the glaucoma was ascertained as accidental nonpenetrated cornea trauma by owner, Ophthalmic examination revealed that the left eye was buphthalmic with severe episcleral congestion, pain and fever. The direct pupillary light response could not be evaluated in the left eye, but right eye had normal reaction. The intraocular pressure was 4.5 mmHg in the right eye and 33 mmHg in the left eye, as measured with a Schiotz tonometer, Ultrasonographic finding revealed hyperechoic vitrous body and central echofree material. The Schirmer tear test showed 20 mm in the left eye and 8 mm in the right eye. The hematologic examination revealed monocytosis. The initial medical treatment was admitted, but there was no response. Transpalpebral enucleation in the left eye under inhalation anesthesia with enflurane 1.2 vol% in oxygen was performed. The day after operation the left eye ravealed no exudate, and pain, and the systemic vital signs were normal. The prognosis is excellent.

• Korean Journal of Biological Psychiatry
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• v.2 no.2
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• pp.275-280
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• 1995

Smooth pursuit eye movement, one of the reliable biological markers of schizophrenia, is not always abnormal in schizophrenic patients. Therefore the authors studied it in schizophrenic patients and normal controls and compared the results according to the presence or abscence of family history of psychosis and types (type I and type II). The results are as follows: 1) In the 18 normal control group (8 mole, 10 female), there was no sex difference in the responses of smooth pursuit eye movement. 2) In th 44 schizophrenic group (28 male, 16 female), there also was no sex difference in the responses of smooth pursuit eye movement. 3) In comparison of 44 schizophrenic group to 18 normal control group, there was significantly increased abnormal response in smooth pursuit eye movement in schizophrenic group (P < 0.005). 4) In schizophrenic group, there was no difference in the responses of smooth pursuit eye movement between type I and type II schizophrenia. 5) The presence or abscence of family history of psychosis made no difference in the responses of smooth pursuit eye movement in schizophrenic group. 6) Subdivision of type I or type II in each case of presence or abscence of family history made no difference in the responses of smooth pursuit eye movement in schizophrenic group.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.3
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• pp.371-376
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• 2014

Purpose: The aim of this study was to explore the effect of artificially decreased eye in normal vision on eye-hand coordination (EHC) when using the Lee-Ryan Eye-Hand Coordination Test recently reported. Methods: Eleven adults with normal vision aged $29.46{\pm}5.94$ years participated for this study where a non-dominant eye artificially induced moderate refractive amblyopic vision at near by adding a plus lens conducted EHC tasks and then did the test again under normal vision following 2 weeks. To investigate the ability of EHC, 7 tasks including individually different level of difficulty in the Lee-Ryan EHC Test were selected to compare and analyze EHC in terms of two independent variables such as time taken and the number of errors. Results: In time taken, subjects with artificially decreased vision took more time than normal vision under monocular conditions (p=0.013), while those with the decreased vision completed their tasks faster than normal vision under binocular conditions (p=0.001). In the number of errors, subjects with the decreased vision made more mistakes (p<0.001) as shown in time taken, whereas there was no difference between monocular and binocular viewing conditions in the decreased vision. Conclusions: Unlike previous EHC tests including limitations for application, deficit in EHC can be screened by the Lee-Ryan EHC Test developed based on simple computer-based system. Therefore, it is considered that further studies relevant to deficits in visual function such as amblyopia will be carried out in clinics as well as research.

• Journal of Veterinary Science
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• v.24 no.2
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• pp.32.1-32.10
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• 2023

Background: The association between vitamin D and canine keratoconjunctivitis sicca (KCS) has not been investigated in dogs. Objectives: To investigate the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with Schirmer tear test 1 (STT-1) and tear film breakup time (TFBUT) in dogs. Methods: Sixty-one clinically healthy, client-owned dogs were enrolled. STT-1 and TFBUT were measured in 122 (61dogs) and 82 (41 dogs out of total 61 dogs) eyes, respectively. Serum 25(OH)D concentrations were evaluated by quantitative chemiluminescent immunoassay. The dogs were classified into 6 groups according to the evaluations (STT-1: group 1, normal [≥ 15 mm/min] in both eyes; group 2, normal in one eye and abnormal [< 15 mm/min] in the fellow eye; group 3, abnormal in both eyes; TFBUT: group 4, normal [≥ 20 sec] in both eyes; group 5, normal in one eye and abnormal [< 20 sec] in the fellow eye; group 6, abnormal in both eyes). Results: STT-1 was positively correlated with TFBUT (p < 0.001). Among the STT-1 groups, the mean serum 25(OH)D concentration in group 1 was significantly higher than in groups 2 and 3 with positive correlation (p < 0.001). However, there were no significant differences among the TFBUT groups 4, 5, and 6. Conclusions: In dogs, it was found that serum 25(OH)D concentrations had a greater effect on quantitative KCS than qualitative KCS. Therefore, it is considered that measurement of serum 25(OH)D concentration could be included in the diagnostic tests in canine quantitative KCS patients.