• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.1A
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• pp.31-43
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• 2009

In this study, the numerical method is presented, which can consider the various train types and can solve the equations of motion for a vehicle-bridge interaction analysis by non-iteration procedure through formulating the coupled equations of motion. The coupled equations of motion for the vehicle-bridge interaction are solved by the Newmark ${\beta}$ of a direct integration method, and by composing the effective stiffness matrix and the effective force vector according to a analysis step, those can be solved with the same manner of the solving procedure of equilibrium equations in static analysis. Also, the effective stiffness matrix is reconstructed by the Skyline method for increasing the analysis effectiveness. The Cholesky's matrix decomposition scheme is applied to the analysis procedure for minimizing the numerical errors that can be generated in directly calculating the inverse matrix. The equations of motion for the conventional trains are derived, and the numerical models of the conventional trains are idealized by a set of linear springs and dashpots with 16 degrees of freedom. The bridge models are simplified by the 3 dimensional space frame element which is based on the Euler-Bernoulli theory. The rail irregularities of vertical and lateral directions are generated by the PSD functions of the Federal Railroad Administration (FRA). The results of the vehicle-bridge interaction analysis are verified by the experimental results for the railway plate girder bridges of a span length with 12 m, 18 m, and the experimental and analytical data are applied to the low pass filtering scheme, and the basis frequency of the filtering is a 2 times of the 1st fundamental frequency of a bridge bending.

• Molecules and Cells
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• v.46 no.9
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• pp.545-557
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• 2023

Sphingomyelinase (SMase) catalyzes ceramide production from sphingomyelin. Ceramides are critical in cellular responses such as apoptosis. They enhance mitochondrial outer membrane permeabilization (MOMP) through self-assembly in the mitochondrial outer membrane to form channels that release cytochrome c from intermembrane space (IMS) into the cytosol, triggering caspase-9 activation. However, the SMase involved in MOMP is yet to be identified. Here, we identified a mitochondrial Mg²⁺-independent SMase (mt-iSMase) from rat brain, which was purified 6,130-fold using a Percoll gradient, pulled down with biotinylated sphingomyelin, and subjected to Mono Q anion exchange. A single peak of mt-iSMase activity was eluted at a molecular mass of approximately 65 kDa using Superose 6 gel filtration. The purified enzyme showed optimal activity at pH of 6.5 and was inhibited by dithiothreitol and Mg²⁺, Mn²⁺, Ni²⁺, Cu²⁺, Zn²⁺, Fe²⁺, and Fe³⁺ ions. It was also inhibited by GW4869, which is a non-competitive inhibitor of Mg²⁺-dependent neutral SMase 2 (encoded by SMPD3), that protects against cytochrome c release-mediated cell death. Subfractionation experiments showed that mt-iSMase localizes in the IMS of the mitochondria, implying that mt-iSMase may play a critical role in generating ceramides for MOMP, cytochrome c release, and apoptosis. These data suggest that the purified enzyme in this study is a novel SMase.

• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.6
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• pp.79-85
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• 2023

Skid resistance pavement is an accessory to the road and is a facility for the safe driving of cars by increasing the skid resistance of road pavement. In particular, in bad weather conditions such as snow, rain, and black ice, the skid resistance performance of skid resistance pavement greatly affects the safety of road traffic and drivers. However, BPT(British Pendulum Tester) has a test area of only 0.009 m², making it difficult to represent the overall packaging surface. A reliable method of evaluating slip resistance performance is needed for maintaining non-slip packaging. In this study, the conventional BPT test and the skid resistance performance evaluation method of the PFT(Pavement Friction Tester) and µGT(Micro Grip Tester) tests were compared through guidelines and standard investigations and applied to the field skid resistance performance evaluation. In addition, skid resistance pavement with different skid resistance performance was installed at the test-bed and actual road demonstration sites to compare BPN(British Pendulum Number), SN(Skid Number), GN(Grip Number), and to derive correlations for each performance evaluation method. As a result of the experiment, SN and GN showed similar skid resistance performance, and the GN value was derived similar to BPN × 0.01.

• Journal of Biomedical Engineering Research
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• v.44 no.6
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• pp.450-464
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• 2023

Pulse oximetry, a non-invasive technique for evaluating blood oxygen saturation, conventionally depends on isolated measurements, rendering it vulnerable to factors like illumination profile, spatial blood flow fluctuations, and skin pigmentation. Previous efforts to address these issues through imaging systems often employed red and near-infrared illuminations with distinct profiles, leading to inconsistent ratios of transmitted light and the potential for errors in calculating spatial oxygen saturation distributions. While an integrating sphere was recently utilized as an illumination source to achieve uniform red and near-infrared illumination profiles on the sample surface, its bulkiness presented practical challenges. In this work, we have enhanced the pulse oximetry imaging system by transitioning illumination from an integrating sphere to a multi-wavelength LED configuration. This adjustment ensures simultaneous emission of red and near-infrared light from the same position, creating a homogeneous illumination profile on the sample surface. This approach guarantees consistent patterns of red and near-infrared illuminations that are spatially uniform. The sustained ratio between transmitted red and near-infrared light across space enables precise calculation of the spatial distribution of oxygen saturation, making our pulse oximetry imaging system more compact and portable without compromising accuracy. Our work significantly contributes to obtaining spatial information on blood oxygen saturation, providing valuable insights into tissue oxygenation in peripheral regions.

• Journal of Korean Neurosurgical Society
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• v.66 no.6
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• pp.681-689
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• 2023

Objective : Subarachnoid hemorrhage (SAH) is a condition characterized by bleeding in the subarachnoid space, often resulting from the rupture of a cerebral aneurysm. Delayed cerebral ischemia caused by vasospasm is a significant cause of mortality and morbidity in SAH patients, and inflammatory markers such as systemic inflammatory response index (SIRI), systemic inflammatory index (SII), neutrophil-to-lymphocyte ratio (NLR), and derived NLR (dNLR) have shown potential in predicting clinical vasospasm and outcomes in SAH patients. This article aims to investigate the relationship between inflammatory markers and cerebral vasospasm after aneurysmatic SAH (aSAH) and evaluate the predictive value of various indices, including SIRI, SII, NLR, and dNLR, in predicting clinical vasospasm. Methods : A retrospective analysis was performed on a cohort of 96 patients who met the inclusion criteria out of a total of 139 patients admitted Trakya University Hospital with a confirmed diagnosis of aSAH between January 2013 and December 2021. Diagnostic procedures, neurological examinations, and laboratory tests were performed to assess the patients' condition. The Student's t-test compared age variables, while the chi-square test compared categorical variables between the non-vasospasm (NVS) and vasospasm (VS) groups. Receiver operating characteristic (ROC) curve analyses were used to evaluate the diagnostic accuracy of laboratory parameters, calculating the area under the ROC curve, cut-off values, sensitivity, and specificity. A significance level of p<0.05 was considered statistically significant. Results : The study included 96 patients divided into two groups : NVS and VS. Various laboratory parameters, such as NLR, SII, and dNLR, were measured daily for 15 days, and statistically significant differences were found in NLR on 7 days, with specific cut-off values identified for each day. SII showed a significant difference on day 9, while dNLR had significant differences on days 2, 4, and 9. Graphs depicting the values of these markers for each day are provided. Conclusion : Neuroinflammatory biomarkers, when used alongside radiology and scoring scales, can aid in predicting prognosis, determining severity and treatment decisions for aSAH, and further studies with larger patient groups are needed to gain more insights.

• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.779-785
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• 2023

In the creation of non-verbal dance performance, stage costumes are an important element of visual expression and serve an expanded role in addition to its fundamental decorativeness, representation of status reflective of the historical setting of the act and functionality for the dance movement. We intends that the purpose of this research is to analyze the expanded role of the costumes in the creative ballet <'That' Girl>, and through this exercise, provide foundational data on and suggest new future directions for stage costume design. <'That' Girl> is composed of two acts, offering condolences and eliciting empathy by conveying the fear experienced by the victims of the time. The second dance act representing freedom and "Haan" requires this expanded application of costume design. The costume design was inspired by the "Statue of Peace" representing comfort women, and completed through three draft designs and material experiments testing the ease of operation of the strings and fabrics installed in the costumes as well as the functionality of the associated ballet movements. In conclusion, expansion of time & space, expansion of form and expansion of symbolic expression were shown in the dance of liberation using strings wrapped around the arms and through the cloth embodying 'Haan' hidden in front of the costume.

• Journal of the Korean Institute of Landscape Architecture
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• v.52 no.1
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• pp.34-45
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• 2024

Companion animals are increasingly being recognized as members of society in outdoor public spaces. However, the presence of dogs in cities has become a subject of conflict between pet owners and non-pet owners, causing problems in terms of hygiene and noise. This study was conducted to analyze public complaint data using the keywords 'dog,' 'pet,' and 'puppy' through text mining techniques to identify the causes of conflicts in outdoor public spaces related to dogs and to identify key issues. The main findings of the study are as follows. First, the majority of dog-related complaints were related to the use of outdoor public spaces. Second, different types of outdoor public spaces have different spatial issues. Third, there were a total of four topics of dog-related complaints: 'Requesting a dog playground', 'Raising safety issues related to animals', 'Using facilities other than dog-only areas', and 'Requesting increased park management and enforcement related to pet tickets'. This study analyzed the perceptions of citizens surrounding pets at a time when the creation and use of public spaces related to pets are expanding. In particular, it is significant in that it applied a new method of collecting public opinions by adopting complaint data that clearly presents problems and requests.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.26 no.4
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• pp.17-34
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• 2023

Camera trapping has been used as a non-invasive survey method that minimizes anthropogenic disturbance to ecosystems. Nevertheless, it is labor-intensive and time-consuming, requiring researchers to quantify species and populations. In this study, we aimed to improve the preprocessing of camera trapping data by utilizing an object detection algorithm. Wildlife monitoring using unmanned sensor cameras was conducted in a forested urban forest and a green space on a university campus in Cheonan City, Chungcheongnam-do, Korea. The collected camera trapping data were classified by a researcher to identify the occurrence of species. The data was then used to test the performance of the YOLO-X object detection algorithm for wildlife detection. The camera trapping resulted in 10,500 images of the urban forest and 51,974 images of green spaces on campus. Out of the total 62,474 images, 52,993 images (84.82%) were found to be false positives, while 9,481 images (15.18%) were found to contain wildlife. As a result of wildlife monitoring, 19 species of birds, 5 species of mammals, and 1 species of reptile were observed within the study area. In addition, there were statistically significant differences in the frequency of occurrence of the following species according to the type of urban greenery: Parus varius(t = -3.035, p < 0.01), Parus major(t = 2.112, p < 0.05), Passer montanus(t = 2.112, p < 0.05), Paradoxornis webbianus(t = 2.112, p < 0.05), Turdus hortulorum(t = -4.026, p < 0.001), and Sitta europaea(t = -2.189, p < 0.05). The detection performance of the YOLO-X model for wildlife occurrence was analyzed, and it successfully classified 94.2% of the camera trapping data. In particular, the number of true positive predictions was 7,809 images and the number of false negative predictions was 51,044 images. In this study, the object detection algorithm YOLO-X model was used to detect the presence of wildlife in the camera trapping data. In this study, the YOLO-X model was used with a filter activated to detect 10 specific animal taxa out of the 80 classes trained on the COCO dataset, without any additional training. In future studies, it is necessary to create and apply training data for key occurrence species to make the model suitable for wildlife monitoring.

• The Korean Journal of Air & Space Law and Policy
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• v.17
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• pp.55-89
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• 2003

What are the international aviation regimes? It is said that they are sets of principles, norms, rules, and decision-making procedures of international aviation around which aviation actors' (states-actors, intergovernmental aviation organization, international aviation conventions, airlines and their organizations etc.) expectations converge in a given aviation issue-area for the purposes of the human welfare and the operations of the stable civil aviation. In this regards, the purposes of this study are focused on the aviation actors' shifts. Chronologically, international aviation regimes have been developed by some stages as followings; The 1st stage is the period from 1944 Chicago Convention to 1978 US Deregulation Act, when the aviation regulations and rules within the international aviation relations were implemented by Chicago-Bermuda regimes as Christer Jonsson pointed out. In this first stage, the sovereignty for the airspace over their countries is absolute. The second stage is the period from 1978 to '1992 Open Skies Agreement' between US and Netherlands. In this regime, airlines' activities as well as state-actors' have been actuated. The third stage is the period from 1992 to the contemporary. In this stage, airlines' activities for the consumers such as 'Open Skies Agreements', 'e-commerce business', 'airspace open policy within EU area', 'service open policy of WTO', and 'airlines' strategic alliance' are the central focal points in the world aviation relationship. In the conclusion, this phenomenon of the core actors in the international aviation rules has been shifted from the states-actors to the non-states actors especially, operating airlines, or consuming customers. Finally, I' d like to suggest that international aviation regimes should be developed to promote and facilitate the globalized level for the people's movements among the global aviation society. That is the way to proceed to the welfare and peace for all human beings of the World.

• Journal of the Korean Institute of Landscape Architecture
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• v.39 no.3
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• pp.83-97
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• 2011

The purpose of this study is to perform a gap analysis between public-private partnership urban parks of Korea currently in their initial stage and various foreign cases that have been established in terms of planning(formation of public-private partnership${\rightarrow}$creation of parks${\rightarrow}$operation and management of parks) and to propose improvements for each process of planning. As a result of the gap analysis on domestic and foreign public-private partnership urban parks, the future course to be followed by urban Korean parks can be summarized as follows. First, if the public-private urban parks that exist at present were led by a single or small number of partners centered on local government entities, urban parks from that point on must be created and managed based on efficient multi-sector partnerships. Since urban parks are public spaces where public benefit is more important than profit, diverse voices of public-private sectors must be reflected with a long-term perspective. Second, urban parks are not a place to be completed but a public space which continues to develop. Therefore, they must be approached with a focus on the process instead of the result. The existing concept of domestic public-private partnership is inclined to creation of urban parks. This suggests than the government had been focusing only on quantitative increase in urban parks. In order to create values as a public space for local communities, public-private partnership is also required in operation and management of urban parks. Third, public-private partnership management of urban parks can become more effective through active community participation. Participation by local communities takes long time because transition in the consciousness about values of urban parks must be presumed. Thus in Korea, non-profit organization like Seoul Green Trust should accumulate successful creation and management of small and large urban parks through public-private partnership will settle in our nation.