• Title/Summary/Keyword: non-linear calibration

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Fundamental Investigation of Non-invasive Determination of Glucose by Near Infrared Spectrophotometry (근적외선 분광법을 이용한 비침투적 혈당 분석법 개발에 관한 기초 연구)

  • Kim, Hyo J.;Woo, Young A.;Chang, Soo H.;Cho, Chang H.;Cantrell, Kevin;Piepmeier, Edward H.
    • Analytical Science and Technology
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    • v.11 no.1
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    • pp.47-53
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    • 1998
  • This study is to improve the diagnosis of diabetes mellitus and the self-monitoring of blood glucose in people with diabetes by providing a non-invasive method of monitoring blood glucose. A near-infrared (NIR) spectrophotometer was used to measure absorption spectra of 80 glucose samples ranges from 1 mg/dL to 200 mg/dL, and shows the standard error of prediction 1.8 mg/dL. Also, to investigate the effect of interference in blood, NaCl and sand were added in glucose and found the standard error of prediction of 2.8 mg/dL and 3.8 mg/dL, respectively. A new and more accurate calibration system for the spectrophotometer was developed from systematic study of light scattering, which cause nonlinear spectrophotometer response.

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A Self-Calibrated Localization System using Chirp Spread Spectrum in a Wireless Sensor Network

  • Kim, Seong-Joong;Park, Dong-Joo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.7 no.2
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    • pp.253-270
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    • 2013
  • To achieve accurate localization information, complex algorithms that have high computational complexity are usually implemented. In addition, many of these algorithms have been developed to overcome several limitations, e.g., obstruction interference in multi-path and non-line-of-sight (NLOS) environments. However, localization systems those have complex design experience latency when operating multiple mobile nodes occupying various channels and try to compensate for inaccurate distance values. To operate multiple mobile nodes concurrently, we propose a localization system with both low complexity and high accuracy and that is based on a chirp spread spectrum (CSS) radio. The proposed localization system is composed of accurate ranging values that are analyzed by simple linear regression that utilizes a Big-$O(n^2)$ of only a few data points and an algorithm with a self-calibration feature. The performance of the proposed localization system is verified by means of actual experiments. The results show a mean error of about 1 m and multiple mobile node operation in a $100{\times}35m^2$ environment under NLOS condition.

Continuous Blood Pressure Monitoring using Pulse Wave Transit Time

  • Jeong, Gu-Young;Yu, Kee-Ho;Kim, Nam-Gyun
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.834-837
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    • 2005
  • In this paper, we describe the method of non-invasive blood pressure measurement using pulse wave transit time(PWTT). PWTT is a new parameter involved with a vascular that can indicate the change of BP. PWTT is measured by continuous monitoring of ECG and pulse wave. No additional sensors or modules are required. In many cases, the change of PWTT correlates with the change of BP. We measure pulse wave using the photo plethysmograph(PPG) sensor in an earlobe and we measure ECG using the ECG monitoring device our made in the chest. The measurement device for detecting pulse wave consists of infrared LED for transmitted light illumination, pin photodiode as light detector, amplifier and filter. We composed 0.5Hz high pass, 60Hz notch and 10Hz low pass filter. ECG measurement device consists of multiplexer, amplifier, filter, micro-controller and RF module. After amplification and filtering, ECG signal and pulse wave is fed through micro-controller. We performed the initial work towards the development of ambulatory BP monitoring system using PWTT. An earlobe is suitable place to measure PPG signal without the restraint in daily work. From the results, we can know that the dependence of PWTT on BP is almost linear and it is possible to monitoring an individual BP continuously after the individual calibration.

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Selecting Significant Wavelengths to Predict Chlorophyll Content of Grafted Cucumber Seedlings Using Hyperspectral Images

  • Jang, Sung Hyuk;Hwang, Yong Kee;Lee, Ho Jun;Lee, Jae Su;Kim, Yong Hyeon
    • Korean Journal of Remote Sensing
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    • v.34 no.4
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    • pp.681-692
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    • 2018
  • This study was performed to select the significant wavelengths for predicting the chlorophyll content of grafted cucumber seedlings using hyperspectral images. The visible and near-infrared (VNIR) images and the short-wave infrared images of cucumber cotyledon samples were measured by two hyperspectral cameras. A correlation coefficient spectrum (CCS), a stepwise multiple linear regression (SMLR), and partial least squares (PLS) regression were used to determine significant wavelengths. Some wavelengths at 501, 505, 510, 543, 548, 619, 718, 723, and 727 nm were selected by CCS, SMLR, and PLS as significant wavelengths for estimating chlorophyll content. The results from the calibration models built by SMLR and PLS showed fair relationship between measured and predicted chlorophyll concentration. It was concluded that the hyperspectral imaging technique in the VNIR region is suggested effective for estimating the chlorophyll content of grafted cucumber leaves, non-destructively.

Feature Based Multi-Resolution Registration of Blurred Images for Image Mosaic

  • Fang, Xianyong;Luo, Bin;He, Biao;Wu, Hao
    • International Journal of CAD/CAM
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    • v.9 no.1
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    • pp.37-46
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    • 2010
  • Existing methods for the registration of blurred images are efficient for the artificially blurred images or a planar registration, but not suitable for the naturally blurred images existing in the real image mosaic process. In this paper, we attempt to resolve this problem and propose a method for a distortion-free stitching of naturally blurred images for image mosaic. It adopts a multi-resolution and robust feature based inter-layer mosaic together. In each layer, Harris corner detector is chosen to effectively detect features and RANSAC is used to find reliable matches for further calibration as well as an initial homography as the initial motion of next layer. Simplex and subspace trust region methods are used consequently to estimate the stable focal length and rotation matrix through the transformation property of feature matches. In order to stitch multiple images together, an iterative registration strategy is also adopted to estimate the focal length of each image. Experimental results demonstrate the performance of the proposed method.

Sensitivity assessment for climate change on Daecheong Dam Basin stream flow (기후변화에 따른 대청댐 상류유역의 유출 민감도 분석)

  • Seo, Hyeong-Deok;Jeong, Sang-Man;Han, Kyu-Ha;Shin, Kwang-Seob
    • 한국방재학회:학술대회논문집
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    • 2008.02a
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    • pp.695-698
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    • 2008
  • The SWAT model was used to assess the impacts of potential future climate change on the hydrology of the Upper Geum River Basin(UGRB). Calibration and validation of SWAT were performed on a monthly basis for 1982-1995 and 1996-2005, respectively. The impact of ten 15-year(1988-2002) scenarios were then analyzed relative to a scenario baseline. Among them, scenario 1-6 were set to show the sensitivity response. A doubling of atmospheric CO2 concentration was predicted to result in an maximum monthly flow increase of 11 percent. Non-linear impacts were predicted among precipitation change scenarios of -42, -17, 17, and 42 percent, which resulted in average annual flow changes in UGRB of -55, -24, 26, and 65 percent.

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A Pilot Study of Evaluating the Reliability and Validity of Pattern Identification Tool for Insomnia and Analyzing Correlation with Psychological Tests (불면증 변증도구 신뢰도와 타당도 평가 및 심리검사와의 상관성에 대한 초기연구)

  • Jeong, Jin-Hyung;Lee, Ji-Yoon;Kim, Ju-Yeon;Kim, Si-Yeon;Kang, Wee-Chang;Lim, Jung Hwa;Kim, Bo Kyung;Jung, In Chul
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.1
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    • pp.1-12
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    • 2020
  • Objectives: The purpose of this study was to evaluate the reliability and validity of the instrument on pattern identification for insomnia (PIT-Insomnia) and verify the correlation between PIT-Insomnia and psychological tests. Methods: Two evaluators examined the pattern identification of the participants who met insomnia disorder diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition (DSM-5) and took the Insomnia Severity Index (ISI) score over 15 once manually and twice using the PIT-Insomnia to measure the inter-rater and test-retest reliability. We also conducted the following surveys: the Pittsburgh Sleep Quality Index (PSQI), the Korean version of Beck's depression inventory (K-BDI), the Korean version of the State-Trait Anxiety Inventory (STAI-K), the Korean Symptom checklist-95 (KSCL-95), and the EuroQol-5 dimension (EQ-5D), to measure concurrent validity and correlation between the PTI-Insomnia and psychological tests. Results: 1. The test-retest reliability analysis of the pattern identification results showed moderate agreement, and test-retest reliability analysis of each pattern identification score showed agreements from poor to moderate. 2. The inter-rater reliability analysis of the pattern identification results via manual showed slight agreement, when analysis was performed with calibration, the inter-rater reliability analysis of the pattern identification results via manual showed fair agreement. 3. The concordance analysis between results via manual and the PIT-Insomnia showed poor agreement, when the analysis was performed with calibration, concordance analysis showed fair agreement. 4. The concordance analysis between the PIT-Insomnia and the PSQI showed positive linear correlation. 5. The concordance analysis between the PIT-Insomnia and the PSQI, K-BDI, STAI-K, KSCL-95, and EQ-5D showed that non-interaction between the heart and kidney have positive linear correlation with the K-BDI, anxiety item of KSCL-95, dual deficiency of the heart-spleen have positive linear correlation with somatization item of KSCL-95, paranoia item of KSCL-95, heart deficiency with timidity have positive linear correlation with stress vulnerability item of KSCL-95, parania item of KSCL-95, phlegm-fire harassing the heart have positive linear correlation with K-BDI, paranoia item of KSCL-95, depressed liver qi transforming into fire have positive linear correlation with the anxiety item of KSCL-95, parania item of KSCL-95, all pattern identification have negative linear correlation with EQ-5D. Conclusions: The PIT-Insomnia has moderate agreement of reliability and reflects the severity of insomnia since it has some concurrent validity with the PSQI. There are some correlations between the PTI-Insomnia with specific psychological tests, so we could suggest it can be used appropriately in the clinical situation.

Numerical Investigation on Soot Primary Particle Size Using Time Resolved Laser Induced Incandescence (TIRE-LII) (시분해 레이저 유도 백열법을 이용한 매연 입자 크기에 관한 수치적 연구)

  • Lee, Jong-Ho;Kim, Jeong-Yong;Jeong, Dong-Soo;Chang, Young-June;Jeon, Chung-Hwan
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.29 no.9 s.240
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    • pp.1022-1031
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    • 2005
  • Temporal behavior of the laser induced incandescence (LII) signal is often used for soot particle sizing, which is possible because the cooling behavior of a laser heated particle is dependent on the particle size. In present study, LII signals of soot particles are modeled using two non-linear coupled differential equations deduced from the energy- and mass-balance of the process. The objective of this study is to obtain an appropriate calibration curve for determining primary particle size by comparing the gated signal ratio and double-exponential curve fitting methods. Not only the effects of laser fluence and gas temperature on the cooling behavior but also heat transfer mechanisms of heated soot particle have been investigated. The second-order exponential curve fitting showed better agreements with the LII signals than the gated signal ratio method which was based on the lust-order exponential curve fit. And the temporal decay rate of the LII signal and primary particle size showed nearly linear relationship, which was little dependent on the laser fluence. And it also could be reconfirmed that vaporization was dominant process of heat loss during first loons after laser pulse, then heat conduction played most important role while thermal radiation had little influence all the time.

The Radio-Immunoassay Method for Ginsenoside $Rg_1$ of Korean Ginseng

  • Han, Byung-Hoon;Han, Yong-Nam;Sankawa, Ushio;Akyama, Minko;Kawashima, Koichiro
    • Korean Journal of Pharmacognosy
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    • v.11 no.3_4 s.43
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    • pp.133-140
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    • 1980
  • In order to develop the radio-immunoassay procedure for the ginsenoside $Rg_1$ we prepared the $Rg_1-BSA$ conjugate and $Rg_1-tyramine$ conjugate by condensing the $Rg_1-azide$, which was prepared by a series of six step chemical modification of the $Rg_1-side$ chain, with bovine serum albumin(BSA) or with tyramine. Rabbits were immunized by repeated injection of $Rg_1-BSA$ conjugate with Freund's Complete Adjuvant for 5 month long to obtain very potent $anti-Rg_1$ serum. The radio-labelled haptene was prepared by direct radio-iodination $(125_J)$ of $Rg_1-tyramine$ according to the chloramine-T method. The radio-immunoassay procedure was successfully furnished by using DCC method (dextran coated charcoal) and the anti-body titer of the anti-serum was found as being $1600{\sim}3200$ by using 15000cpm tracer per test. Calibration test using non-labelled $Rg_1$ showed linear competetive binding response in the $(8-300){\times}34pg$. range of non-labelled $Rg_1$. The cross reaction test using 19 ginsenoside analogues enabled us a full structure-activity analysis on the antigen-antibody reaction that the anti-body in the serum would recognize the full structure of ginsenoside $Rg_1$ except the side chain moiety.

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Possibility of the Nondestructive Quality Evaluation of Apples using Near-infrared Spectroscopy (근적외 분광분석법을 응용한 사과의 비파괴 품질 측정 가능성 조사)

  • Sohn, Mi-Ryeong;Kwon, Young-Kil;Lee, Kyung-Hee;Park, Woo-Churl;Cho, Rae-Kwang
    • Applied Biological Chemistry
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    • v.41 no.2
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    • pp.153-159
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    • 1998
  • A possibility of evaluation of the major internal quality factors-Brix, moisture contents, firmness and acid content in the Korean domestic 'Fuji'apple fruits by near-infrared reflectance spectroscopic (NIRS) methods were investigated. A multiple linear regression(MLR) analysis between the data obtained by physico- chemical analysis method using refractometer, freeze drier, texture analyzer and titrater and NIR spectral data was carried out to make a calibration. The standard error of prediction(SEP) of Brix, moisture, firmness and acid content were $0.50^{\circ}Brix,\;0.64%,\;0.14kg/cm^2$ and 0.07%. It is concluded that NIRS methods can be used to evaluate Brix and moisture contents of in a apple non-destructive and rapid way but the accuracy for determination of firmness and acid content was slightly low.

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