• Journal of Microbiology and Biotechnology
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• v.16 no.6
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• pp.880-888
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• 2006

Pleurocidin, an $\alpha$-helical cationic antimicrobial peptide, was isolated from skin mucosa of winter flounder (Pleuronectes americamus). It had strong antimicrobial activities against Gram-positive and Gram-negative bacteria, but had very weak hemolytic activity. The Gly$^{13,17}\rightarrow$Ala analog (pleurocidin-AA) showed similar antibacterial activities, but had dramatically increased hemolytic activity. The bacterial cell selectivity of pleurocidin was confirmed through the membrane-disrupting and membrane-binding affinities using dye leakage, tryptophan fluorescence blue shift, and tryptophan quenching experiments. However, the non-cell-selective antimicrobial peptide, pleurocidin-AA, interacts strongly with both negatively charged and zwitterionic phospholipid membranes, the latter of which are the major constituents of the outer leaflet of erythrocytes. Circular dihroism spectra showed that pleurocidin-AA has much higher contents of $\alpha$-helical conformation than pleurocidin. The tertiary structure determined by NMR spectroscopy showed that pleurocidin has a flexible. structure between the long helix from $Gly^3$ to $Gly^{17}$ and the short helix from $Gly^{17}$ to $Leu^{25}$. Cell-selective antimicrobial peptide pleurocidin interacts strongly with negatively charged phospholipid membranes, which mimic bacterial membranes. Structural flexibility between the two helices may play a key role in bacterial cell selectivity of pleurocidin.

• Journal of Korea Multimedia Society
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• v.10 no.11
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• pp.1384-1397
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• 2007

This paper proposes fast storage techniques for hybrid query of data streams. DSMS(Data Stream Management System) have been researched for processing data streams that have busting income. To process hybrid query that retrieve both current incoming data streams and past data streams data streams have to be stored into disk. But due to fast input speed of data stream and memory and disk space limitation, the main research is not about querying to stored data streams but about querying to current incoming data streams. Proposed techniques of this paper use circular buffer for maximizing memory utility and for make non blocking insertion possible. Data in a disk is compressed to maximize the number of data in the disk. Through experiences, proposed technique show that bursting insertion is stored fast.

• Journal of the Society of Naval Architects of Korea
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• v.51 no.4
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• pp.265-273
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• 2014

Wave-body interaction is simulated using a developed code based on the flux-difference splitting scheme for immiscible and incompressible fluids and the hybrid Cartesian/immersed boundary method. A free surface is captured as a moving contact discontinuity within a fluid domain and an approximated Riemann solver is used to estimate the inviscid flux across the discontinuity. Immersed boundary nodes are identified inside an instantaneous fluid domain near a moving body, then dependent variables are reconstructed at those immersed boundary nodes based on interpolation along local normal lines to the boundary. Free surface flows around an oscillating cylinder are simulated and the computed wave elevations are compared with other reported results. The generation of a solitary wave by a moving wave-maker is simulated and the time histories of wave elevations at two different points are compared with other results. The developed code is applied to simulate body motion of an elastically mounted circular cylinder as a solitary wave passes the body. The force acting on an elastically mounted cylinder is compared with the force acting on a fixed cylinder. Grid independency of the computed body motion is established based on a comparison of results using three different-size grids.

• Wind and Structures
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• v.8 no.2
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• pp.107-120
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• 2005

The quasi-steady approaches to simulate the wind induced vibrations of inclined cables, especially on the rain-wind induced vibration, have been tried by many researchers. However, the steady wind force coefficients used in those methods include only the effects of water rivulet, but not the axial flow effects. The problem is the direct application of the conventional techniques to the inclined cable aerodynamics. Therefore, in this study, the method to implement the axial flow effects in the quasi-steady theory is considered and its applicability to the inclined cable aerodynamics is investigated. Then, it becomes clear that the perforated splitter plate in the wake of non-yawed circular cylinder can include the effects of axial flow in the steady wind force coefficients for inclined cables to a certain extent. Using the lateral force coefficients measured in this study, the quasi-steady theory may explain the wind induced instabilities of the inclined cables only in the relatively high reduced wind velocity region. When the Scruton number is less than around 40, the high speed vortex-induced vibration occurs around the onset wind velocity region of the galloping, and then, the quasi-steady approach cannot be applied for estimating the response of wind-induced vibration of inclined cable.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.74.1-74.1
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• 2014

We study a wraping instability of a geometrically thin, non-self-gravitating disk surrounding binary supermassive black holes on a circular orbit. Such a circumbinay disk is subject to not only tidal torques due Line 8 to the binary gravitational potential but also radiative rorques due to radiation emitted from each accretion disk. We find tat a circumbinary disk initially aligned with the binary orbital plane is unstable to radiation-driven warping beyond the marginally stable warping radius, which is sensitive to both the ratio of vertical to horizontal shear viscosities and the mass-to-energy conversion efficiency. As expected, the tidal torques give no contribution to the growth of warping modes but tend to align the circumbinary disk with the orbital plane. Since the tidal torques can suppress the warping modes in the inner part of circumbinary disk, the circumbinaary disk starts to be warped at the radii larger than the marginally stable warping radius. If the warping radius is of the order of 0.1 pc, a resultant semi-major axis is estimated to be of the order of 10-2 pc to 10-4 pc for 107 Msun black hole. We also discuss the posibility that the central objects of observed warped maser disks in active galactic nuclei are binary supermassive black holes with a triple disk: two accretion disks around the individual black holes and one circumbinary disk surrounding them.

• Journal of Environmental Science International
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• v.20 no.4
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• pp.501-509
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• 2011

Unlike many laboratory-scale studies on absorption of organic compounds (VOCs), limited pilot-scale studies have been reported. Accordingly, the present study was carried out to examine operation parameters for the effective control of a hydrophilic VOC (methyl ethyl ketone, MEK) by applying a circular pilot-scale packed-absorption system (inside diameter 37 cm ${\times}$ height 167 cm). The absorption efficiencies of MEK were investigated for three major operation parameters: input concentration, water flow rate, and ratio of gas flow-rate to washing water amount (water-to-gas ratio). The experimental set-up comprised of the flow control system, generation system, recirculation system, packed-absorption system, and outlet system. For three MEK input concentrations (300, 350, and 750 ppm), absorption efficiencies approached near 95% and then, decreased gradually as the operation time increased, thereby suggesting a non-steady state condition. Under these conditions, higher absorption efficiencies were shown for lower input concentration conditions, which were consistent with those of laboratory-scale studies. However, a steady state condition occurred for two input concentration conditions (100 and 200 ppm), and the difference in absorption efficiencies between these two conditions were insignificant. As supported by an established gas-liquid absorption theory, a higher water flow rate exhibited a greater absorption efficiency. Moreover, as same with the laboratory-scale studies, the absorption efficiencies increased as water-to-gas ratios increased. Meanwhile, regardless of water flow rates or water-to-gas ratios, as the operation time of the absorption became longer, the pH of water increased, but the elevation extent was not substantial (maximum pH difference, 1.1).

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.28 no.4
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• pp.274-279
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• 2002

The purpose of this study is to evaluate the critical maintenance period of absorbable membrane for guided bone regeneration. Fortynine Sprague-Dawley rats weighing about 300g were divided into seven groups. An 8 mm circular full-thickness defect in calvarial bone was made and then cellular acetate porous filter (Millipore $filter^{(R)}$.) was placed on the calvarial bone defect. The filter was removed at 2, 3, 4, 5, 6, 8 and 11 weeks after placement. Rats were sacrificed at 12 weeks the placement of cellular acetate porous filter. The specimens were stained with Hematoxylin-Eosin and observed under light microscope. The amount of regenerated bone was measured from both margin of calvarial bone defect (unit : mm). The results were as follows. Bone regeneration of each experimental group was increased gradually and the bond defect was almost completely filled with new bone in 5-, 6-, 8-, and 11-week experimental group. Histologic findings showed mild inflammatory response and granulation tissue formation without apparent adverse effects on the healing process. In 11-week experimental group, the bone defect was completely filled with new bone containing abundant osteoid which was oriented to the dural side and contribute to bony thickening. We suggest that non-absorbable membrane and bioabsorbable membrane presumably should remain intact for longer than 5 weeks to be effective.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.9
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• pp.775-783
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• 2017

In this paper, an impulsive rendezvous problem by using minimum energy of spacecraft in different orbits is addressed. In particular, the orbits considered in this paper are the general orbits including the elliptic orbit, while most of the orbits considered in the literature have been restricted within co-planar or circular orbits. The constraints for solving this optimization problem are the Kepler's equation formulated with the universal variable, and the final position and velocity of two spacecraft. Also, the Lagrange coefficients, sometimes called as f and g solution, are used to describe the orbit transfer. The proposed method technique is demonstrated through numerical simulation by considering the minimum energy, and both the minimum energy and the wait time, respectively. Finally, it is also verified by comparing with the Hohmann transfer known as the minimum energy trajectory. Although a closed-form solution cannot be obtained, it shows that the suggested technique can provide a new insight to solve various orbital transfer problems.

• Parasites, Hosts and Diseases
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• v.54 no.6
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• pp.803-807
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• 2016

Toxascaris leonina is a common parasitic nematode of wild mammals and has significant impacts on the protection of rare wild animals. To analyze population genetic characteristics of T. leonina from South China tiger, its mitochondrial (mt) genome was sequenced. Its complete circular mt genome was 14,277 bp in length, including 12 proteincoding genes, 22 tRNA genes, 2 rRNA genes, and 2 non-coding regions. The nucleotide composition was biased toward A and T. The most common start codon and stop codon were TTG and TAG, and 4 genes ended with an incomplete stop codon. There were 13 intergenic regions ranging 1 to 10 bp in size. Phylogenetically, T. leonina from a South China tiger was close to canine T. leonina. This study reports for the first time a complete mt genome sequence of T. leonina from the South China tiger, and provides a scientific basis for studying the genetic diversity of nematodes between different hosts.

• Structural Engineering and Mechanics
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• v.27 no.6
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• pp.713-739
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• 2007

Nowadays computers can perform symbolic computations in addition to mere number crunching operations for which they were originally designed. Symbolic computation opens up exciting possibilities in Structural Mechanics and engineering. Classical areas have been increasingly neglected due to the advent of computers as well as general purpose finite element software. But now, classical analysis has reemerged as an attractive computer option due to the capabilities of symbolic computation. The repetitive cycles of simultaneous - equation sets required by the finite element technique can be eliminated by solving a single set in symbolic form, thus generating a truly closed-form solution. This consequently saves in data preparation, storage and execution time. The power of Symbolic computation is demonstrated by six examples by applying symbolic computation 1) to solve coupled shear wall 2) to generate beam element matrices 3) to find the natural frequency of a shear frame using transfer matrix method 4) to find the stresses of a plate subjected to in-plane loading using Levy's approach 5) to draw the influence surface for deflection of an isotropic plate simply supported on all sides 6) to get dynamic equilibrium equations from Lagrange equation. This paper also presents yet another computationally efficient and accurate numerical method which is based on the concept of derivative of a function expressed as a weighted linear sum of the function values at all the mesh points. Again this method is applied to solve the problems of 1) coupled shear wall 2) lateral buckling of thin-walled beams due to moment gradient 3) buckling of a column and 4) static and buckling analysis of circular plates of uniform or non-uniform thickness. The numerical results obtained are compared with those available in existing literature in order to verify their accuracy.