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Antioxidation and Anti-inflammation Activity of Isodon inflexus (Thunb.) Kudo Extract and Its Isolated Substance (산박하 추출물과 분리물질의 항산화 및 항염증 활성)

  • Bu, Hee-Jung;Lee, Sunjoo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.3
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    • pp.257-268
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    • 2016
  • The functions of anti-oxidation and anti-inflammation were investigated with the crude 80% methanol extract, subfractions and henryin isolated from Isodon inflexus (Thunb.) Kudo (I. inflexus (Thunb.) Kudo). Antioxidative ability was evaluated by bioassays using 2, 2-diphenyl-1-1-picrydrazyl (DPPH) free radical scavenging activity, xanthine oxidase inhibition, and superoxide radical scavenging effects. Ethyl acetate and butanol fractions exhibited free radical scavenging activity on superoxide with $IC_{50}$ values of $0.9{\mu}g/mL$, $0.2{\mu}g/mL$, respectively, which were stronger activity than that of allopurinol ($2.2{\mu}g/mL$) as reference. For the inhibition of anti-inflammatory activity in RAW 264.7 cell, the ethyl acetate fraction showed strong inhibition activity NO production, and henryin isolated from its subfraction reduced the activity in a dose-dependent manner. Ethyl acetate fraction and henryin suppressed not only mRNA expression of iNOS and COX-2, but also the mRNA expression of pre-inflammatory cytokines such as, TNF-${\alpha}$, 1L-$1{\beta}$, IL-6, in a dose-dependent manner. These results suggested that ethyl acetate fraction of I. inflexus (Thunb.) Kudo has considerable potential as a cosmetics ingredient with an antioxidant and anti-inflammatory effects and henryin can be applied as an functional reference.

Self-differentiation of University Students and their Responses to Kinetic House-Tree-Person Drawings (대학생의 자아분화와 동적 집-나무-사람 그림 반응특성 연구)

  • 정윤정;최외선
    • Journal of Families and Better Life
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    • v.22 no.4
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    • pp.43-61
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    • 2004
  • The purpose of this study was to verify the usefulness of kinetic House- Tree- Person drawing as a diagnostic measure for the degree of self-differentiation, which is an essential part of college students' development. Participants for the study were four hundred thirty five(272 male and 163 female) university freshmen enrolled in 4-year colleges located in Pusan. The Participants completed a scale of self-differentiation and a Kinetic House- Tree-Person drawings test. The evaluation system for kinetic House-Tree-Person drawings was established based on the indexes of Buck(1948) and Bums(1972) and used exiting literatures as reference. The data were analyzed using means, standard deviations, t-test, one-way ANOVA, and Scheffe's test. The results obtained from the study are as follows: First, the mean level of college students' self-differentiation was 2.81, which is about average. Some significant gender differences were found in the areas of self-intergration, family projection, and emotional separation. Male students scored higher on self-intergration, whereas female students score higher on family projection and emotional separation. Second. self-differentiation was higher when the student drew a house with smoke coming out of the chimney, a single-story house with flat roof, or with detailed description of curtains, roof and roof tiles. Third, self-differentiation seemed to be higher when branches and fruits were included, when there was no expression of roots, when large crowns and branch openings were presented, and when no slant lines or base lines appeared. Forth, self-differentiation showed ㅁ higher level when the portrait shows eyes, mouth and neck without omission, when it included the whole body instead of face only, and when there was no person with just a profile, a back, or with a stiff posture, and when there was no weak and thin lines. Individuality also marked higher if a person was in motion and than one person was added. Finally, self-differentiation showed significant difference according to the overall harmony of the drawing, ordering of contents, hand pressure, the kind and shape of tree, and presence of other persons. The more harmonious the picture was, and the more family members are added, the higher the level of self-differentiation was.

Conservation Strategy on Stream Water Quality in the Mt. Bughansan National Park (II) -­With a Special Reference to the Factor influenced on Stream Water Quality Pollution­- (북한산국립공원의 계류수질 보전 전략 (II) ­-계류수질오염 영향인자를 중심으로­-)

  • Park, Jae-Hyeon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.5 no.1
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    • pp.8-18
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    • 2002
  • This research was conducted to establish the conservation strategy of stream water quality by analyzing the factors influenced on stream water quality in the northeastern part of Mt. Bughansan National Park from July 1998 to October 2001. The number of visitors resulted in the significant increase of electrical conductivity, which affected on pollution of the stream water quality. According to the multiple regression analysis, the pH of the stream water was related to dissolved oxygen and temperature of water at the 1% significant level. The electrical conductivity of the stream water was related to number of visitors, amount of $K^+$ and ${NO_3}^-$, total amount of ions, percentages of $Cl^-$ and $Na^+$ caused by solifluction soil at the 1% significant level. The anions($Cl^-$, ${NO_3}^-$ and ${SO_4}^{2-}$) of the stream water were related to number of visitors, electrical conductivity, air temperature, hardness, amount of ${NO_3}^-$, ${SO_4}^{2-}$, total ions, percentage of $Cl^-$, ${NO_3}^-$, ${SO_4}^{2-}$, amount of $Ca^{2+}$ caused by solifluction soil at the 1% significant level. To prevent the pollution of stream water in the northeastern part of Mt. Bughansan National Park, it is recommended that the number of visitors in the park should be managed and rehabilitated rapidly by measure to eco-friendly during the spring season.

A COMPARATIVE STUDY ON THE SEVERAL FACIAL MEASUREMENT METHOD FOR VERTICAL DIMENSION (수직고경 설정을 위한 안면 계측방법에 관한 비교 연구)

  • Park, Jong-Hwan;Oh, Sang-Chun;Dong, Jin-Keun
    • The Journal of Korean Academy of Prosthodontics
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    • v.33 no.1
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    • pp.75-84
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    • 1995
  • This study was designed as a reference of vertical dimension in prosthetic treatment. The author analyzed six facial measurements, namely, (1) the height of lower face at maximum intercuspal position, (2) the height of lower face at resting position, (3) midface, (4) external ear and lateral wall of orbit, (5) interpupillary distance, (6) distance between pupil and mouth in the 100 Won-kwang Univ. Dental collage students(50 : male, 50 : female), who have normal occlusion, no posterior prosthesis, no experience of orthodontic treatment, and no deformity of facial soft tissue and no temporomandibular dysfunction. The results of this study were as follows : 1. The length of midface was shortest and the inter-pupillary distance was longest in both male and female. 2. The length difference with the length of midface and lower face at maximum intercuspal position was 5.64mm in male and 2.23mm in female, so the lower face was longer, 3. The facial measuring component, similar to lower face at maximum intercuspation, was the length of between medial wall of external ear and lateral wall of orbit. It's difference was 1.3mm in male, 1.77mm in female, and the lower face was shorter. 4. The difference of lower facial length in resting position and maximum intercuspation was 2.48mm in male, 2.24mm in female, the length of resting position was therefore longer. 5. The most clost correlation with the height of maximum intercuspal positioning lower face was resting lower face in both groups.

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A study on physical activities by applying a social cognitive theory (사회인지이론을 적용한 신체활동에 관한 문헌고찰)

  • Han, Eun-Ok;Moon, In-Ok
    • The Journal of Korean Society for School & Community Health Education
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    • v.6
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    • pp.117-126
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    • 2005
  • This study attempted to extract a suggestive point to help the design of a program, which is used to promote physical activities, by applying a social cognitive theory based on literature review on the physical activity based on a social cognitive theory. This study considers 10 journal articles that used a social cognitive theory, physical activity, and exercise as the major variable using the EBSCOhost Academic Search Premier and Educator's Reference Desk (ERIC). The type of papers was analyzed using a certain criterion, which can be configured according to the number of each year's papers, characteristics of research subjects, application type of a social cognitive theory, and classification of the application of objects in a social cognitive theory. The characteristics of each year's papers presented no specific characteristics for each year's papers, but the study in 2004 especially presented a high level. The characteristics of research subjects presented four highest cases in the case of the college student, and there were zero cases for children. The application type of studies on physical activities using a social cognitive theory can be largely classified as three types. The results of the measurement using a sectional investigation for SCT objects were 2 cases, the application of SCT for promoting physical activities was 1 case, and the demonstration of evaluation for the effect of SCT objects presented 8 highest cases. Although the social cognitive theory in the characteristics of the classification of object applications can be classified as 10 objects, there were no cases that used 10 all objects, partial applications of the object were measured in 8 studies, and two cases presented no detailed considerations on the object. Most of studies used a part of the object where the application of self-efficacy were measured by 8 highest cases. In addition, there were no measurements on the situation, observation learning, answer and response, and self-management. The elements of attitude, cognitive activity, self-efficacy, and handicaps among the SCT object were commonly used, and studies that the self-efficacy largely affects on the promotion of physical activities presented the main current.

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Worker Symptom-based Chemical Substance Estimation System Design Using Knowledge Base (지식베이스를 이용한 작업자 증상 기반 화학물질 추정 시스템 설계)

  • Ju, Yongtaek;Lee, Donghoon;Shin, Eunji;Yoo, Sangwoo;Shin, Dongil
    • Journal of the Korean Institute of Gas
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    • v.25 no.3
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    • pp.9-15
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    • 2021
  • In this paper, a study on the construction of a knowledge base based on natural language processing and the design of a chemical substance estimation system for the development of a knowledge service for a real-time sensor information fusion detection system and symptoms of contact with chemical substances in industrial sites. The information on 499 chemical substances contact symptoms from the Wireless Information System for Emergency Responders(WISER) program provided by the National Institutes of Health(NIH) in the United States was used as a reference. AllegroGraph 7.0.1 was used, input triples are Cas No., Synonyms, Symptom, SMILES, InChl, and Formula. As a result of establishing the knowledge base, it was confirmed that 39 symptoms based on ammonia (CAS No: 7664-41-7) were the same as those of the WISER program. Through this, a method of establishing was proposed knowledge base for the symptom extraction process of the chemical substance estimation system.

A comparison of subtracted images from dental subtraction programs (디지털공제프로그램간의 디지털공제영상 비교)

  • Han Won-Jeong
    • Imaging Science in Dentistry
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    • v.32 no.3
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    • pp.147-151
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    • 2002
  • Purpose: To compare the standard deviation of gray levels on digital subtracted images obtained by different dental subtraction programs. Materials and Methods: Paired periapical films were taken at the lower premolar and molar areas of the phantoms involving human mandible. The bite registration group used Rinn XCP equipment and bite registration material, based on polyvinyl siloxane, for standardization. The no bite registration group used only Rinn XCP equipment. The periapical film images were digitized at 1200 dpi resolution and 256 gray levels by a flat bed scanner with transparency unit. Dental digital subtraction programs used for this study were Subtractor (Biomedisys Co., Korea) and Emago (Oral Diagnostic Systems, The Netherlands). To measure the similarities between the subtracted images, the standard deviations of the gray levels were obtained using a histogram of subtracted images, which were then analyzed statistically. Results: Subtracted images obtained by using the Emago program without manual selection of corresponding points showed the lowest standard deviation of gray levels (p<0.01). And the standard deviation of gray levels was lower in subtracted images in the group of a bite registration than in the group of no use of bite registration (p < 0.01). Conclusion: Digital radiographic subtraction without manual selection of reference points was found to be a convenient and superior method.

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Voltammetric Studies of Anion Transfer Reactions Across a Microhole Array-Water/PVC-NPOE Gel Interface

  • Hossain, Md. Mokarrom;Girault, Hubert H.;Lee, Hye-Jin
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1734-1740
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    • 2012
  • Voltammetric characterization of hydrophilic anion transfer processes across a 66 microhole array interface between the water and polyvinylchloride-2-nitrophenyloctylether gel layer is demonstrated. Since the transfer of hydrophilic anions including $Br^-$, $NO_3{^-}$, $I^-$, $SCN^-$ and $ClO_4{^-}$ across the liquid/gel interface usually sets the potential window within a negative potential region, a highly hydrophobic organic electrolyte, tetraoctylammonium tetrakis(pentafluorophenyl)borate, providing a wider potential window was incorporated into the gel phase. The transfer reaction of perchlorate anions across the microhole-water/gel interface was first studied using cyclic voltammetry and differential pulse voltammetry. The full voltammetric response of perchlorate anion transfer was then used as a reference for evaluating the half-wave transfer potentials, the formal transfer potentials and the formal Gibbs transfer energies of more hydrophilic anions such as $Br^-$, $NO_3{^-}$, $I^-$, and $SCN^-$. The current response associated with the perchlorate anion transfer across the micro-water/gel interface versus the perchlorate concentration was also demonstrated for sensing applications.

Target Velocity Estimation using FFT Method

  • Lee, Kwan Hyeong
    • International Journal of Internet, Broadcasting and Communication
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    • v.12 no.3
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    • pp.1-8
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    • 2020
  • This paper studied a method of estimating target information using a radar in wireless communication. Position information on the target can be estimated angle, distance and velocity. The velocity information can be estimated since the Doppler frequency is changed in the moving target. The signal incident on the receiving array antenna is multiplied by the delay time and the reference signal to represent the output signal. This output signal is estimated by applying FFT (Fast Fourier Transform) after calculating signal correlation through correlation integrator. Since the output signal must be calculated within the correlator, it should be processed with the Dwell time. The correlation signal of the correlation integrator outside this Dwell time is indicated by the velocity measurement error. The FFT is applied to the signal that has passed through the correlated integrator in order to estimate the distance of the signal. The Doppler resolution must be improved because the FFT estimates target information using the Doppler information. The Doppler resolution decreases with increasing the integration time. The velocity information estimation should have no spread of the velocity. As a result of the simulation, there was no spread of the target velocity in this study.

A New DPWM Method to Suppress the Low Frequency Oscillation of the Neutral-Point Voltage for NPC Three-Level Inverters

  • Lyu, Jianguo;Hu, Wenbin;Wu, Fuyun;Yao, Kai;Wu, Junji
    • Journal of Power Electronics
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    • v.15 no.5
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    • pp.1207-1216
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    • 2015
  • In order to suppress the low frequency oscillation of the neutral-point voltage for three-level inverters, this paper proposes a new discontinuous pulse width modulation (DPWM) control method. The conventional sinusoidal pulse width modulation (SPWM) control has no effect on balancing the neutral-point voltage. Based on the basic control principle of DPWM, the relationship between the reference space voltage vector and the neutral-point current is analyzed. The proposed method suppresses the low frequency oscillation of the neutral-point voltage by keeping the switches of a certain phase no switching in one carrier cycle. So the operating time of the positive and negative small vectors is equal. Comparing with the conventional SPWM control method, the proposed DPWM control method suppresses the low frequency oscillation of the neutral-point voltage, decreases the output waveform harmonics, and increases both the output waveform quality and the system efficiency. An experiment has been realized by a neutral-point clamped (NPC) three-level inverter prototype based on STM32F407-CPLD. The experimental results verify the correctness of the theoretical analysis and the effectiveness of the proposed DPWM method.