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Herbal Medicine for Coronavirus Disease 2019 (COVID-19) in Children: a Literature Review

  • Jihong Lee;In-Jun Yang
    • The Journal of Pediatrics of Korean Medicine
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    • v.37 no.3
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    • pp.17-34
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    • 2023
  • Objectives Few studies to date reviewed herbal medicines prescribed to pediatric patients with coronavirus disease 2019 (COVID-19). We aimed to summarize and analyze these herbal medicines. Methods Nine databases were searched for studies published up until November 24, 2020. Nine case reports and one case series involving 17 pediatric patients were included in the study. The clinical symptoms, interventions, outcomes, pattern identification, composition, and frequency of herbal medicine administration were analyzed. Results The symptoms of pediatric patients with COVID-19 treated with herbal medicines were mild or moderate. Herbal medicines have been used to alleviate symptoms, such as fever and cough. No adverse events were reported. All of the patients who received herbal medicines were discharged from the hospital after symptomatic relief. Pattern identification revealed that the lungs were the most affected organs. Epidemic toxins, wind, dampness, and heat were the primary etiological factors. More pediatric patients with COVID-19 were prescribed a combination of herbal and Western medicines than herbal medicines alone. The frequently used herbs include Glycyrrhizae Radix et Rhizoma, Lonicerae Flos, Scutellariae Radix, Armeniacae Semen, Citri Reticulatae Pericarpium, and Astragali Radix. Conclusions Our review can serve as a reference for the treatment of COVID-19 in children.

Normative Issues in Next Generation Sequencing Gene Testing

  • Na-Kyoung Kim
    • Development and Reproduction
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    • v.27 no.1
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    • pp.47-56
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    • 2023
  • Despite the commercialization of Next generation sequencing (NGS) gene testing, only a few studies have addressed the various ethical and legal problems associated with NGS testing in Korea Here, we reviewed the normative issues that emerged at each stage of the wet analysis and bioinformatics analysis of NGS gene testing. In particular, it was in mind to apply various international guidelines and the principles of bioethics to actual clinical practice. Considering the characteristics of NGS testing, wet analysis of additional testing can be justified if presumptive consent is recognized. Furthermore, the medical relationship between diseases needs to be established and it should be clear that the patient would have given consent if the patient had been aware of the correlation between genes. At the stage of bioinformatics analysis, the question of unsolicited findings arises. In case of unsolicited and relevant findings, according to American College of Medical Genetics and Genomics (ACMG), a recognized relationship between genes and diseases needs to be established. In case of unsolicited and not-relevant findings, it is almost impossible to determine whether knowing or not knowing the findings is more beneficial to the patient. However, it seems to be certain that the psychological harm an individual may suffer from such information is likely to be greater if the disease is severe and if there is no cure. The list of genes for which the ACMG guidelines impose reporting obligations is a good reference for judgment.

A Study on the Art Management and Cultural Activities in China from the K-Wave Case

  • Jia Ning LI;Su SHUAI;Zhang FAN
    • Journal of Koreanology Reviews
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    • v.2 no.1
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    • pp.27-31
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    • 2023
  • The purpose of this paper is to study the relationship between Art management and Cultural activities in China from the K-wave case. Research design, data, and methodology: This study used the method of the cases study survey, with the K-wave case in as the survey objects, 3 valid survey sample case were collected in this paper. Results: The two dimensions of art management and cultural activities differently influences from the K-wave, and the influence of availability on customer satisfaction is not significant. Conclusion: The results of this study will provide useful reference for the Art management and Cultural activities in China from the K-wave case. And improve the development of art management and cultural activities in China by improving the K-wave of service quality. Art management can shape urban commercial space in a beneficial way, create a good consumption atmosphere, and enhance the attractiveness and competitiveness of the city. The introduction of art elements into urban commercial space can create a strong cultural atmosphere, so that the city presents a smart look. Art management has a positive impact on K-Wave production and operation activities, which can promote the shaping of art commercial space, the promotion of urban cultural atmosphere.

Researching Visual Immersion Elements in VR Game <Half-Life: Alyx>

  • Chenghao Wang;Jeanhun Chung
    • International Journal of Internet, Broadcasting and Communication
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    • v.15 no.2
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    • pp.181-186
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    • 2023
  • With the development of VR technology, the visual immersion of VR games has been greatly enhanced nowadays. There has been an issue that has been troubling players in previous VR games, which is motion sickness. Therefore, VR games have been limited in terms of game mechanics, game duration, and game scale, greatly reducing the immersive experience of visual immersion. However, <Half-Life: Alyx> is different from previous VR games in that players can actually perform spatial displacement in the game scene, rather than being fixed in one place for 360-degree observation and interaction. At the same time, compared to traditional games, VR games no longer need to rely on screens, and the complete visual immersion enhances the fun and playability of the game. This research focuses on the VR game <Half-Life: Alyx> to explore its immersive factors in terms of visual perception. Through in-depth analysis of elements such as color, texture mapping, lighting, etc. in VR games, it was found that the game creates a strong sense of visual immersion in these aspects. Through analysis, it is helpful to gain a deeper understanding of the factors that contribute to visual immersion in VR games, which has certain reference value for game developers and related professionals.

A study on transmission of Chimgyeongyogyeol by Ryu, Seong-ryong (류성룡(柳成龍) 저술 『침경요결(鍼經要訣)』의 전승 연구)

  • Park Hun-pyeong
    • Journal of Korean Medical classics
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    • v.36 no.2
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    • pp.35-48
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    • 2023
  • Objectives : In this paper, the characteristics and significance of Chimgyeongyogyeol (=Chimguyogyeol) were analyzed. Furthermore, the purpose of this study is to examine which books were based on the origin of the medical knowledge enjoyed by Ryu, Seongryong at the time. Methods : The bibliography of each transmitted version of Chimgyeongyogyeol is considered, then the items are compared, and finally, the citations of the relevant contents are examined. Cited literature was analyzed by item, and sources were identified where the contents were cited. Results : 1. Chimgyeongyogyeol was published three times. 2. At present, it is not known which tradition text is the oldest. The transmission relationship between several transmission versions is not clear. 3. Chimgyeongyogyeol was written with reference to various other medical books, centered on Uihagibmun. 4. There is no information about 'Choose a day to perform acupuncture' and 'Zaoyuju acupuncture', which were widely popular in Joseon at the time. This reflects the purpose of writing to convey medical knowledge to the general public. Conclusions : Chimgyeongyogyeol was an acupuncture book written for the purpose of conveying medical knowledge to the common people by reflecting the latest medical achievements in China. Through this, the knowledge of acupuncture enjoyed by the author and what he aimed for through it were confirmed. However, it was impossible to completely compose the system of the first draft only with the extant version.

Perception of agricultural biotechnology according to information navigation activities on agricultural biotechnology

  • Bumkyu, Lee;Sung-Dug, Oh;Youn Sung, Cho
    • Korean Journal of Agricultural Science
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    • v.48 no.4
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    • pp.761-770
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    • 2021
  • A study was undertaken to identify variations in the level of awareness, the information collection status, the level of acceptance, and the characteristics of information collection as it pertains to agricultural biotechnology based on information collection in the field of agricultural biotechnology. When examining subjective awareness, objective awareness, and interest in agricultural biotechnology, the results showed that the levels of all three variables were higher in cases where information exploration of agricultural biotechnology had been experienced. Among the participants who have experience in voluntarily collecting information about agricultural biotechnology, helpful information at a rate of 51.6% and harmful information at a rate of 42.0% were acquired, values much higher than the 37% and 30% corresponding rates for participants who had no experience. However, it was also found that harmful information has a significantly greater impact on perceptions of the future. The characteristics of information collection for agricultural biotechnology indicated that those with experience in voluntary information collection particularly preferred the Internet, whereas those without any experience showed little difference with regard to television and/or the internet. According to a survey of participants' interest areas in agricultural biotechnology and their level of information acquisition, "Safety of human bodies" was rated the top interest area at 36.9%, which also had the highest level of information acquisition at 30.0%. In providing and sharing information in the future, this is a direct reference to the priorities and proportions of each field.

The Importance of Nursing Ethics for Establishing a Life-Respect Community -Focusing on the Korean War-

  • Eun Young, Jung
    • International Journal of Advanced Culture Technology
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    • v.11 no.2
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    • pp.202-209
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    • 2023
  • This study attempted to identify the ethical principles of nurses who realized care in the war field with a nurse's unique professional spirit, and to explore a more specialized and subdivided concept of ethical nursing in the future. War has occurred frequently in history, and the outcome has always been tragic. There are always different opinions about what it means to discuss the ethics of these wars. Despite these controversies, the ethics of nursing, which always takes care of the sick at the scene of war, is interpreted regardless of war. The ethical spirit of nursing is to respect life and take care of those who need help. Whether the person asking for help is a soldier or a civilian, it doesn't matter where it is or what the purpose of the war is. Nursing practiced nursing based on the principle of bioethics for all, even in war scenes where there was no ethical reference point. This study explains that it is necessary to inherit the spirit of nursing, which practiced ethical care even in such cruel scenes of the past, and to protect the ethical fundamental spirit of nursing even in the changing environment in the future society.

The Effect of Critical Work Factors on Job Motivation and Satisfaction: An Empirical Study from Vietnam

  • PHAM, Thao-Vy;HUANG, Yung-Fu;DO, Manh-Hoang
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.1
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    • pp.399-408
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    • 2022
  • This paper aims to evaluate the effects of Critical work factors on Work Motivation and Job Satisfaction of young Vietnamese employees. The four most essential work aspects were consisting of the Work environment, Employee empowerment, Salary, and Promotion opportunities. To empirically evaluate the proposed research model, the authors assemble data through conducting questionnaire interviews with young employees working in Vietnamese firms. A sample of 216 respondents was constructed using the PLS-SEM program to highlight the testing of thirteen hypotheses. The testing results indicate that four Critical work factors positively impact the job motivation of young employees, especially two factors as Salary and Promotion opportunities. Surprisingly, the hypothesis regarding the positive direct relationship between Promotion opportunities and Job satisfaction is not supported. Meanwhile, the rest influence factors have a significant connection with the Vietnamese worker's job satisfaction. The mediation role of Work motivation was also tested by examining the indirect positive relationship between four Critical work factors and Job satisfaction. This paper is the first study that focuses on young employees; hence, these research findings provide Vietnamese human resource managers some suggestions for reference, which can be considered the dynamic factors on the young Vietnamese employees.

The Impact of Oil Price Inflation on Economic Growth of Oil Importing Economies: Empirical Evidence from Pakistan

  • LIAQAT, Malka;ASHRAF, Ayesha;NISAR, Shoaib;KHURSHEED, Aisha
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.1
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    • pp.167-176
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    • 2022
  • By analyzing the impact of oil prices on economic growth, this study has shown a new insight into the link between oil price inflation and economic growth. The primary goal of this study is to determine if oil prices are pro-growth or anti-growth. To provide empirical proof, the series data for both the core and control variables from 1972 to 2020 was used to justify the association on empirical grounds. To account for the presence of a unit root, the Augmented Dickey-Fuller Test was used, and after making the series compatible for co-integration, the Autoregressive distributed lag model was used to determine the empirical estimate. Additionally, the empirical models were used to diagnose heteroscedasticity and autocorrelation. The reference point model reveals that in developing nations like Pakistan, economic growth is anti-growth with an increase in prices, and it responds negatively to economic growth in the long and short run. As a result, oil price inflation in Pakistan fails to have a significant beneficial impact on economic growth in both the long and short run, but it does raise the general price level in the economy.

Development of reverse-transcription loop-mediated isothermal amplification assays for point-of-care testing of human influenza virus subtypes H1N1 and H3N2

  • Ji-Soo Kang;Mi-Ran Seo;Yeun-Jun Chung
    • Genomics & Informatics
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    • v.20 no.4
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    • pp.46.1-46.7
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    • 2022
  • Influenza A virus (IAV) is the most widespread pathogen causing human respiratory infections. Although polymerase chain reaction (PCR)-based methods are currently the most commonly used tools for IAV detection, PCR is not ideal for point-of-care testing. In this study, we aimed to develop a more rapid and sensitive method than PCR-based tools to detect IAV using loop-mediated isothermal amplification (LAMP) technology. We designed reverse-transcriptional (RT)-LAMP primers targeting the hemagglutinin gene. RNAs from reference H1N1 and H3N2 showed specific RT-LAMP signals with the designed primers. We optimized the reaction conditions and developed universal reaction conditions for both LAMP assays. Under these conditions, the detection limit was 50 copies for both RT-LAMP assays. There was no non-specific signal to 19 non-IAV respiratory viruses, such as influenza B virus, coronaviruses, and respiratory syncytial viruses. Regarding the reaction time, a positive signal was detected within 25 min after starting the reaction. In conclusion, our RT-LAMP assay has high sensitivity and specificity for the detection of the H1 and H3 subtypes, making it suitable for point-of-care IAV testing.