Kim Seok Kyun;Jung Sang Mi;Ahn Kyong Hoon;Jeon Hyung Jun;Lee Dong Hun;Jung Kwang Mook;Jung Sung Yun;Kim Dae Kyong
Archives of Pharmacal Research
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v.28
no.8
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pp.923-929
/
2005
Methanol extracts of domestic plants of Korea were evaluated as a potential inhibitor of neutral pH optimum and membrane-associated 60 kDa sphingomyelinase (N-SMase) activity. In this study, we partially purified N-SMase from bovine brain membranes using ammonium sulfate. It was purified approximately 163-fold by the sequential use of DE52, Butyl-Toyopearl, DEAE-Cellulose, and Phenyl-5PW column chromatographies. The purified N-SMase activity was assayed in the presence of the plant extracts of three hundreds species. Based on the in vitro assay, three plant extracts significantly inhibited the N-SMase activity in a time- and concentration-dependent manner. To further examine the inhibitory pattern, a Dixon plot was constructed for each of the plant extracts. The extracts of Abies nephrolepis, Acer tegmentosum, and Ginkgo biloba revealed a competitive inhibition with the inhibition constant (Ki) of $11.9 {\mu}g/mL,\;9.4{\mu}g/mL,\;and\;12.9{\mu}g/mL$, respectively. These extracts also inhibited in a dose-dependent manner the production of ceramide induced by serum deprivation in human neuroblastoma cell line SH-SY5Y.
Current research explores the effect of language on the perception of facial emotion as suggested by the psychological construction theory of emotion by using a psychophysical method. In this study, we hypothesize that the perception of facial expression may be influenced if the observer is shown an affective word before he/she judges an expression. Moreover, we suggest that his/her understanding of a facial emotion will be in line with the conceptual context that the word denotes. During the two experiments conducted for this project, a control stimulus or words representing either angry or happy emotions were briefly presented to participants before they were shown a target face. These target faces were randomly selected from seven faces that were gradually morphed to show neutral to angry (in Experiment 1) and neutral to happy (in Experiment 2) expressions. The participants were asked to perform a two-alternative forced choice (2AFC) task to judge the emotion of the target face (i.e., decide whether it is angry or neutral, or happy or neutral). The results of Experiment 1 (when compared with the control condition) showed that words denoting anger decreased the point of subjective equality (PSE) for judging the emotion of the target as anger, whereas words denoting happiness increased the PSE. Experiment 2, in which participants had to judge expressions on a scale from happy to neutral, produced a contrasting pattern of results. The outcomes of this study support the claim of the psychological construction theory of emotion that the perception of facial emotion is an active construction process that may be influenced by information (such as affective words) that provide conceptual context.
The maritime blockade has long been used as a means of war in that it serves as a bridge for economic warfare by paralyzing enemy maritime transport, although it is not a decisive battle, and in the Korean War, U.N. forces have achieved significant results in the war with limited maritime blockade through the Clark Line. However, with China emerging as a maritime powers based on its strong naval power, there is a lack of consideration on how to set up a blockade to block maritime activities and how to respond neutral ships or carrying wartime contraband products if war breaks out again on the Korean Peninsula, In addition, since maritime blockade should be used as a sensitive and flexible naval force projection in that it has interests with neutral countries, it should be carefully reviewed in that it can be used only through careful and reasonable judgment considering the principle of ensuring the legality of maritime blockade Therefore, in this study, Reexamine the process of change in the application of the International Law of Blockade, and through this, Derive the basic principle of ensuring the legitimacy of maritime blockade. In addition, by reviewing the application of these basic principles in the waters off the Korean Peninsula at wartime, we presented answers to research questions by reviewing what needs to be done to neutral ships and ships carrying wartime contraband products, and considered the implications for us
Journal of Korean Society of Coastal and Ocean Engineers
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v.14
no.3
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pp.232-239
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2002
This paper studies the behavior of mooring line of silt protector according to the change of sea level. It is found from the analysis of the behavior that if the taut cable length has been determined appropriately within the range of safety factor, the tensioned cable has almost constant tension regardless of the water depth. The whole structure, however, becomes unstable due to the loss (zero tension) of the released cable tension. It is also recognized from the investigation for the effect of intial straight line angle on the behavior of mooring line that the design through the conceptually combined consideration of the cable tension, total scope and buoy deflection has to be required in the mooring analysis. Finally, the material of cable is not damaged because the cable tension is reduced by attached shellfish, but the whole structure may be also unstable by the effect on the anchor angle, total scope and buoy deflection.
Several studies have reported the presence of sodium excess objects having neutral atomic absorption lines at $5895{\AA}$ (NaD) and $8190{\AA}$ that are deeper than expected based on stellar population models that match the stellar continuum. The origin of these lines is therefore hotly debated. van Dokkum & Conroy proposed that low-mass stars (0.3M) are more prevalent in massive early-type galaxies, which may lead to a strong NaI 8190 line strength. It is necessary to test this prediction, however, against other prominent optical line indices such as NaD, Mgb, and Fe5270, which can be measured with a significantly higher signal-to-noise ratio than NaI 8190. We identified a new sample of roughly one thousand NaD excess objects (NEOs; ~8% of galaxies in the sample) based on NaD line strength in the redshift range 0.00${\alpha}$-enhanced" ([${\alpha}/Fe$] ~ 0.3), "metal-rich" ([Z/H] ~ 0.3), and, especially, "Na-enhanced" ([Na/Fe] ~ 0.3).
The application of the superconducting fault current limiter (SFCL) in a power distribution system is expected to contribute the voltage-sag suppression of the bus line as well as the fault-current reduction of the fault line. However, the application effects of the SFCL on the voltage sag of the bus line including the fault current are dependent on its application location in a power distribution system. In this paper, we investigated the fault current limiting and the voltage sag suppressing characteristics of the SFCL due to its application location such as the outgoing point of the feeder, the bus line, the neutral line and the 2nd side of the main transformer in a power distribution system, and analyzed the trace variations of the bus-voltage and fault-feeder current. The simulated power distribution system, which was composed of the universal power source, two transformers with the parallel connection and the impedance load banks connected with the 2nd side of the transformer through the power transmission lines, was constructed and the short-circuit tests for the constructed system were carried out. Through the analysis on the short-circuit tests for the simulated power distribution system with the SFCLs applied into its representative locations, the effects from the SFCL's application on the power distribution system were discussed from the viewpoints of both the suppression of the bus-voltage sag and the reduction of the fault current.
Kim, Jeom-Sik;Kim, Do-Young;Park, Yong-Beom;Kwon, Sin-Won;Gil, Kyung-Suk
The Transactions of the Korean Institute of Electrical Engineers P
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v.59
no.4
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pp.434-439
/
2010
This study fabricated a simulation facility which reduced the structure of a current distribution line to 50:1 in order to analyze the induced lightning shielding effect of a 22.9kV-Y distribution line according to ground resistance capacity, grounding locations, etc. When installing an overhead ground wire, the standard for grounding a distribution line with a current of 22.9kV-Y requires that ground resistance in common use with the neutral line be maintained less than $50\Omega$every 200m span. The reduced line for simulation had 7 electric poles and induced lightning was applied to the ground plane 2m apart from the line in a direction perpendicular to it using an impulse generator. If induced voltage occurred in the line and induced current flowed through the line due to the applied current, the induced voltage and current of the 'A' phase were measured respectively using an oscilloscope. When all 7 electric poles were grounded with a ground resistance of less than $50\Omega$ respectively, the combined resistance of the line was $7.4\Omega$. When an average current of 230A was applied, the average induced voltage and current measured were 1,052V and 13.8A, respectively. Under the same conditions, when the number of grounding locations was reduced, the combined resistance as well as induced voltage and current showed a tendency to increase. When all 7 electric poles were grounded with a ground resistance of less than $100\Omega$, the combined resistance of the line was $14.9\Omega$. When an average current of 236A was applied, the average induced voltage and current of the 'A' phase calculated were 1,068V and 15.6A, respectively. That is, in this case, only the combined resistance was greater than when all 7 electrical poles were grounded, and the induced voltage and current were reduced. Therefore, it is thought that even though ground resistance is slightly higher under a construction environment with the same conditions, it is advantageous to ground all electric poles to ensure system safety.
Specific or non-specific cytolytic processes of free-living amoebae causing meningoencephalitls have been emphasized and the cytolytic ability related to hydrolases in Entantoeba sp. and Naegleria sp. has also been reported since the latter half of 1970's. However, no information on hydrolase activities in Acanthamoeba sp. is available. Hydrolases in Acanthamoeba culbertsoni, a pathogenic species of free-living amoebae, were assayed and compared with those in a non-pathogenic species, A. royreba. Pathogenicity of these two species was confirmed through experimental infection to BALB/c mice. Hydrolase activities and cytotoxic effects between pathogenic and non.pathogenic species were compared in the trophozoites cultured in CGV media and in CHO cell line, respectively. The results are summarized as follows: 1. The mice infected with A. culbertseni were all dead 15 days after nasal inoculation, and the mean survival time was 8.5 days. Also the mice infected with this pathogenic species manifested typical meningoencephalitis, whereas the mice infected with A. royreba did not. 2. Hydrolases detected both in the cell extracts and culture media were acid phosphatase, ${\beta}-N-acetyl$ galactosaminidase, ${\beta}-N-acetyl$ glucosaminidase, ${\alpha}-mannosidase$, neutral proteinase and acid proteinase, all of which were detected with remarkably higher rate in A. culbertsoni than in A. royreba. 3. A. cuzbertsoni revealed strong cytotoxicity for the target CHO cells, whereas A. royreba did not show any specific cytotoxicity. About 80% of the target cells mixed with A. culbertsoni were dead 48 hours after cultivation, and more than 95% of the target cells were dead 72 hours after cultivation. 4. Hydrolase activities in A. culbertsoni cultured with the target cell line were assayed according to the culture time. The activities of acid phosphatase, ${\beta}-N-acetyl$ galactosaminidase, ${\beta}-N-acetyl$ glucosaminidase, ${\alpha}-mannosidase$ and acid proteinase in this pathogenic amoeba were detected higher in amoeba extracts than in culture media up to 120 hours after cultivation, but after 120 hours of cultivation those activities were detected higher in culture media than in the amoeba Iysates. Neutral proteinase activity in A. culbertsoni increased more in EBSS medium than in the Iysate specimens although the activity in the extracts was generally steady according to the cultivation time. Summarizing the above results, it is concluded that there were differences in hydrolase activities between Pathogenic A. culbertsoni and non-pathogenic A. royreba, and that some hydrolase activities were detected remarkably higher in A. culbertsoni which revealed strong cytotoxicity to the target CHO cell line.
Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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v.22
no.4
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pp.130-138
/
2008
The tendency of lightning surge to propagate is a eared variously depend on the power system and subject equipment of protection. However, looking into the subject equipment with the lightning surge, the invasion route of lightning surge can be divided in between the two lines of power, between the power line and the ground, the power line and the PE conductor, between the neutral line and the ground and the like. In addition, in the event of the communication equipment, there exists the route of lightning surge incoming from between the communication lines, the communication line and the ground in addition to the power lines. In this study, the tendency of propagation of lightning surge penetrated on to the subject equipment is analyzed through the empirical experiment in accordance with the ground method by using the independent ground, common ground and bypass arrester ground for safety improvement in power lines.
Kim, In-Soo;Han, Woong;Yeo, Sang-Min;Kim, Chul-Hwan;Weon, Bong-Ju;Lim, Yong-Hun
The Transactions of The Korean Institute of Electrical Engineers
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v.58
no.3
/
pp.431-436
/
2009
As the telecommunication lines bring into widespread use, one of the most important aspects related to power distribution systems is effectively to evaluate the effect on the telecommunication lines from power lines. One of the efficient methods to evaluate the effect is to measure the induced voltage of a telecommunication line as a result of a ground-loop. If the power lines cause high induced voltage, the ground reference in the telecommunication lines is no longer a stable potential, so signals may ride on the noise. A ground loop is common wiring conditions where a ground current may take more than one path to return to the grounding electrode at the arrangement between the power lines and telecommunication lines. When a multi-path connection between the power lines and telecommunication line circuits exists, the resulting arrangement is known as a ground loop. Whenever a ground loop exists, there are potential for damages or abnormal operations of the telecommunication lines. The power lines can induce the voltage on the communication line. The effects can be calculated by considering the inductances and capacitances. However, if we assume that there are only power lines, it doesn't have a practical meaning because there are conductors with other purpose in the neighborhood of the lines. If we consider that case, we need more complex system. Therefore we suggest more complex system considering the conductors with other purpose in the neighborhood of the lines. The neutral wires and the overhead ground wires are considered for calculating the induced voltage. We assume that there are the messenger wires beside the power line as a result of increased use of them. The main purpose of this paper is a study on a shielding effect of messenger wires in the distribution lines. EMTP(Electro-Magnetic Transients Program) program is used for the induced voltage calculation.
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