• Title/Summary/Keyword: nerve system

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Effect of Electrical Stimulation of Peripheral Nerve on Pain Reaction (말초신경자극이 동통반응에 미치는 영향)

  • Paik, Kwang-Se;Chung, Jin-Mo;Nam, Taick-Sang;Kang, Doo-Hee
    • The Korean Journal of Physiology
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    • v.15 no.2
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    • pp.73-81
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    • 1981
  • Experiments were conducted in ischemic decerebrate cats to study the effects of electroacupuncture and electrical stimulation of peripheral nerve on pain reaction. Flexion reflex was used as an index of pain. The reflex was elicited by stimulating the sural nerve(20 V, 0.5 msec duration) and recorded as a compound action potential from the nerve innervated to the semitendinosus muscle. Electroacupuncture was performed, using a 23-gauge hyperdermic needle, on the tsusanli point in the lateral upper tibia of the ipsilateral hindlimb. The common peroneal nerve was selected as a peripheral nerve which may be associated with electroacupuncture action, as it runs through the tissue portion under the tsusanli point. Both for electroacupuncture and the stimulation of common peroneal nerve a stimulus of 20 V-intensity, 2 msec-duration and 2 Hz-frequency was applied for 60 min. The results are summerized as follows: 1) The electroacupuncture markedly depressed the flexion reflex; this effect was eliminated by systemic application of naloxone $(0.02{\sim}0.12\;mg/kg)$, a specific narcotic antagonist. 2) Similarly, the electrical stimulation of the common peroneal nerve significantly depressed the flexion reflex, the effect being reversed by naloxone. 3) When most of the afferent nerves excluding sural nerve in the ipsilateral hindlimb were cut, the effect of electroacupuncture on the flexion reflex was not observed. Whereas direct stimulation of the common peroneal nerve at the proximal end from the cut resulted in a significant reduction of the flexion reflex, again the effect was reversible by naloxone application. 4) Transection of the spinal cord at the thoracic 12 did not eliminate the effect of peripheral nerve stimulation on the flexion reflex and its reversal by naloxone, although the effect was significantly less than that in the animal with spinal cord intact. These results suggest that: 1) the analgesic effect of an electroacupuncture is directly mediated by the nervous system and involves morphine-like substances in CNS, 2) the site of analgesic action of electroacupuncture resides mainly in the brainstem and in part in the spinal cord.

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A Study on the Design of Sensory Nerve Conduction Velocity Measurement System (감각신경 전도속도 측정시스템 설계에 관한 연구)

  • Yoo, S.K.;Min, B.G.;Kim, J.W.;Kim, J.W.;Yoon, H.R.;Kim, S.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.11
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    • pp.89-92
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    • 1992
  • The sensory nerve study is the important index to diagnosis peripheral neuromyotic disease. This paper discusses about the design of parameter - latency, amplitude, conduction velocity - measurement system in the sensory nerve. This system consists of three parts which are Main Control Unit(MCU), Stimulator, and external output unit. Also new measurement algorithms which is adaptive threshold method is presented in this paper. The designed system is controlled by MCU includes automatic detection algorithms and self-diagnostic functions.

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A Case Report of Bun-Ton Disease Treated by Yang-Ji-Tang (상복부 통증을 奔豚(奔豚)으로 진단하고 양지장(良枳場)을 투여하여 호전된 1례)

  • Seok, Seon-Hee;Park, Se-Hwan;Kim, Geun-Woo;Koo, Byung-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.19 no.2
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    • pp.265-278
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    • 2008
  • Stress reaction can be shown widely in the systems of psychology, endocrinology, immunology and so on. Stress promotes catecholamine from the autonomic nerve system, and this activates the sympathetic nerve system. As the sympathetic nerve system is activated, high blood pressure, tachycardia, vertigo, anxiety, diaphoresis, myotonic reaction and others can happen. Autonomic imbalance is the syndrome that people suffer from various symptoms accompanying no organic lesions and no psychological disorders by losing the hormonies between the sympathetic and parasympathetic nerve system. We experienced a 55 year-old female who complained of sudden abdominal pain after being frightened at trouble with her husband. Her abdominal pain was very characteristic, "Something is like rising in my abdomen.", that occurred several times a day. We diagnosed 'Bun-Ton Disease' from her abdominal sign. Several oriental medicine books recorded aspects of Bun-Ton disease and treatments, we had given herbal medicine and treated acupuncture be based on those. Results from studies to date suggest the Bun-Ton Disease's main cause is fright or shock, and they stimulate releasing epinephrine or norepinephrine, that result in various symptoms. In this case report, we will present this patient's case and review the Bun-Ton Disease.

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A Study on the Development of Remote Diagnosis System for Nerve Conduction

  • Kim, Jong-Weon
    • Journal of Electrical Engineering and information Science
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    • v.3 no.3
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    • pp.286-291
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    • 1998
  • A remote measurement system for nerve conduction has been developed to aid patients with spinal cord injury by accident. Existing cooperation between rescuers and doctors can be supported through the introduction of multimedia desktop video conferencing. Such facilities provide several advantages over conventional video conferencing. In particular, patients may feel free because they can see a doctor through the video conferencing facilities. This paper describes the system implementation and evaluation. The author considers the network capability and image data handling, and introduces a method a transmit image data for this system.

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The Effect of Acupuncture Stimulation at the BL60, HT8 Acupoint to the Inferior Mesenteric Nerve Activity, Heart Rate and Mean Arterial Blood Pressure in Rats (곤륜(崑崙).소부(少府) 침자(鍼刺)가 하장간막신경(下腸間膜神經) 활성(活性)과 혈압(血壓) 및 심박수(心搏數)에 미치는 영향(影響))

  • Lee Kang-Uk;Yun Yeo-Chung;Kim Jeong-Sang;Na Chang-Su
    • Korean Journal of Acupuncture
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    • v.19 no.2
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    • pp.41-49
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    • 2002
  • Objectives : The aim of the present study is to observe effects of acupuncture related with the nerve system, Inferior mesenteric nerve activity(IMNA) was examined on BL60 acupuncture closely connected with the bladder and HT8 with little tied. Materials and methods : Acupunctures were performed during 100 seconds after stabilization. IMNA was measured by micromanipulator, preamplifier, mean arterial pressure(MAP) and heart rate were observed by blood pressure transducer, 4-channel transducer amplifier in anesthetized rat. Results : On BL60 acupuncture, the heart rate was not significantly decreased but IMNA, MAP were significantly decreased and Maximum peak of IMNA was increased during inserted acupuncture, decreased after ejected acupuncture respectively. On HT8 acupuncture, IMNA was decreased during acupuncture than before acupuncture but the others did not showed signigicant difference. Conclusions : Our results demonstrated a meridian interaction between BL60 acupoint in the bladder channel and Inferior mesenteric sympathetic nerve related to the bladder. This fact suggest that BL60 acupuncture have effect on the bladder through the nerve system. Meanwhile, IMNA was decreased during HT8 acupuncture. This result is supposed HT8 to have not meridian function but acupoint function by another mechanism. It needs to be closely examined other meridians and nerve by the optimal approaching method.

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신경경로의 정보처리에 대한 전기적 특성 연구

  • 박상희;이명호
    • 전기의세계
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    • v.28 no.8
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    • pp.66-71
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    • 1979
  • This paper describes electrical analysis of the information processing of the nervous system. A general-purpose electrical neuronal model for simulating the electrical activity in a single nerve cell and in small groups of nerve cell has constructed. This model consists of two basic electronic modules to represent respectively a "cell body" and an "axon (with synapses)", together with various related appurtenances. The primary advantages of this method are; holistic view, actual physical representation of various electrical activities in a single nerve cell, display of the activity of all nerve cells flexibility with respect to network parameters. Moreover, this model can effectively help push forward our general ability to explore and conceptualize the electrical activity of interconnected networks of nerve cell behaving in concert. Also, this electronic module technique is the best of various means for this task of realistic representation of aggregates of neurons.gregates of neurons.

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A study on the mechanism for reduction of lead-induced toxicity in nervous system by aloe vera (Aloe vera의 연 유도성 신경계 독성 저감 기전에 관한 연구)

  • 정명규;곽영규
    • Journal of Environmental Health Sciences
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    • v.22 no.3
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    • pp.8-16
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    • 1996
  • Effects of water extract of aloe vera on lead-induced neurotoxicity were investigated in sciatic nerve isolated from rat. The mechanism on toxicity reduction by measuring activities of axonal enzymes, metabolism of myo-inositol in nerve, lead concentration in several organs and so on were further examimed. In the lead-treated rats, the transport rate of axonal enzyme, such as acetyl cholinesterase and choline acetyltransferase, was reduced by from 50% to 30% respectively. Reduction in myo-inositol concentration and $Na^+/K^+$ ATPase activity were also observed in sciatic nerve from lead-treated rat. However, the aloe extract administration significantly eliminated the impairment and maintained myo-inositol concentration to about 85% of normal level. Also aloe extract promoted the excretion rate of lead which is accumulated in blood, sciatic nerve and kidney. These results suggest that lead-induced neurotoxicity was significantly reduced by administration of aloe extract and the mechanism might be partly increase in kidney excretion rate of lead and parity normalization of $Na^+/K^+$ ATPase activity which is critical factor in order to keep nerve maintaining normal myo-inositol level.

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Persistent Hiccups Treatment with Cervical Epidural Block -Case reports- (경부 경막외 차단을 이용한 연속성 딸꾹질의 치험 3예 -증례 보고-)

  • Lee, Ji-Hyang;Kim, Jong-Il;Min, Byung-Woo
    • The Korean Journal of Pain
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    • v.10 no.2
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    • pp.241-245
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    • 1997
  • Persistent hiccup is defined as duration lasting longer than 48 hours. Reflex arc of hiccup is divided into three parts : afferent, central, efferent. Afferent portion of the neural pathway of hiccup formation is composed of vagus nerve, phrenic nerve, and sympathetic chain arising from T6 to T12. Efferent limb is phrenic nerve. Hiccup center is located in brain stem, midbrain, reticular system and hypothalamus. Persistent hiccup is very difficult to treat by conventional methods. We performed cervical epidural block of the phrenic nerve root for three patients suffering from persistent hiccup. The therapeutic effect was perfect. The mechanism of the cervical epidural block is not yet defined however it is thought to block the efferent nerve fibers and suppress the reflex arc of hiccup. We conclude cervical epidural block is relatively safe and very effective for treating persistent hiccup.

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Narrative Review of Pathophysiology and Endoscopic Management of Basivertebral and Sinuvertebral Neuropathy for Chronic Back Pain

  • Hyeun Sung Kim;Pang Hung Wu;Il-Tae Jang
    • Journal of Korean Neurosurgical Society
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    • v.66 no.4
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    • pp.344-355
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    • 2023
  • Chronic lower back pain is a leading cause of disability in musculoskeletal system. Degenerative disc disease is one of the main contributing factor of chronic back pain in the aging population in the world. It is postulated that sinuvertebral nerve and basivertebral nerve main mediator of the nociceptive response in degenerative disc disease as a result of neurotization of sinuvertebral and basivertebral nerve. A review in literature is done on the pathoanatomy, pathophysiology and pain generation pathway in degenerative disc disease and chronic back pain and management strategy is discussed in this review to aid understanding of sinuvertebral and basivertebral neuropathy treatment strategies.

Ultrasound Imaging for Position of the Sciatic Nerve Division in Korean Female (한국 여성에서 좌골 신경 분지 위치에 대한 초음파 영상)

  • Nam, Il Hyun;Yeo, Eui Dong;Yu, Ji Soo;Lee, Jun Ho;Lee, Young Koo
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.7 no.1
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    • pp.28-32
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    • 2014
  • Purpose: We aim to determine sciatic nerve bifurcation location and depth at the level of the popliteal fossa in Korean female. Materials and Methods: Thirty three subjects were enrolled in Korean female. M-turbo ultrasound system (SonoSite, bothell, WA, USA)with 38 mm high frequency linear array transducer, 13-6 MHz probe was used for ultrasound measurements. With subject lying prone, the location of the sciatic nerve in relation to the popliteal crease and skin to nerve distance were assessed via ultrasound. Analyses were performed with SAS version 9.3 using multiple linear regression. Results: Thirty three subjects were enrolled. Distance from the popliteal crease to the sciatic nerve was 4.5-7.5 (mean 5.7 cm), and the depth of the sciatic nerve from the skin was 1.8-3.2 (mean 2.4 cm). Multiple linear regression for the usefulness of the model has a p value of 0.036, shows between weight and depth. Conclusion: We show that variability exists for sciatic nerve bifurcation location in Korean female, The success rate is creased if consider the relations between weight and depth when performs sciatic nerve block in Korean female. In our study, a sciatic nerve block is recommend that performed 7.5 cm proximal to the crease in the popliteal fossa.

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